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The map label for this gene is atpA

Identifier: 87200413

GI number: 87200413

Start: 2567075

End: 2568604

Strand: Direct

Name: atpA

Synonym: Saro_2400

Alternate gene names: 87200413

Gene position: 2567075-2568604 (Clockwise)

Preceding gene: 87200412

Following gene: 87200414

Centisome position: 72.08

GC content: 64.51

Gene sequence:

>1530_bases
ATGGAAATCCGCGCCGCTGAAATCTCGAAGGTCATCAAGGACCAGATCGCCAGCTTCGGCACCGAGGCCCAGGTCTCGGA
AGTCGGGTCGGTTCTCTCGGTCGGTGACGGCATCGCCCGCATCCACGGCCTCGACAAGGTCCAGGCCGGTGAAATGGTCG
AATTCTCGAACGGTGTGAAGGGCATGGCCCTGAACCTCGAAGCCGACAACGTCGGCGTCGTGATCTTCGGCTCGGACTCC
GAGATCAAGGAAGGCGACGTCGTCAAGCGCACCGGCACCATCGTCGACGTTCCCGTCGGCAAGGGCCTGCTCGGCCGCGT
GGTCGACGCGCTCGGCAACCCGATCGACGGCAAGGGCCCGATTGTCGACGCCACCCGCCAGCGCGTCGAAGTCAAGGCTC
CCGGCATCATCCCGCGCAAGTCGGTGCACGAACCCGTGCAGACCGGCCTCAAGGCGATCGACGCCCTCGTCCCCGTCGGC
CGTGGCCAGCGCGAGCTGATCATCGGTGACCGTCAGACCGGCAAAACCGCCGTCGCGATCGACACCTTCATCAACCAGAA
GGCCGTCAACGCCGGCACCGACGAAGGCAAGAAGCTCTACTGCATCTACGTCGCCGTCGGCCAGAAGCGCTCGACCGTCG
CGCAGATCGTCCGCCAGCTCGAAGAGAACGGCGCGATGGAATACTCCATCGTCGTGGCCGCGACCGCTTCGGAACCGGCT
CCGCTCCAGTACCTCGCGCCCTACACCGGTGCGACCATGGGTGAATTCTTCCGCGACAACGGCATGCACGCCGTGATCGT
GTACGACGACCTTTCCAAGCAGGCCGTCGCCTACCGTCAGATGTCGCTGCTGCTCCGCCGTCCTCCGGGCCGCGAAGCCT
ACCCCGGTGACGTGTTCTATCTCCACAGCCGCCTGCTCGAGCGCGCCGCGAAGATGAACGACGAAAACGGCGCTGGCTCG
CTCACCGCTCTGCCGATCATCGAAACCCAGGCGGGCGACGTGTCGGCCTACATCCCGACCAACGTGATCTCGATCACCGA
CGGCCAGATCTTCCTTGAAACCGGCCTGTTCTATCAAGGCATCCGTCCGGCCATCAACGTCGGTCTGTCGGTGTCGCGCG
TCGGCTCCTCGGCCCAGACCAAGGCGATGAAGAAGGTTGCCGGCTCAATCAAGCTGGAACTCGCGCAGTACCGCGAAATG
GCGGCCTTCGCGCAGTTCGGTTCGGACCTCGACGCCTCGACCCAGAAGCTCCTCAACCGCGGTGCGCGCCTGACTGAACT
GCTCAAGCAGCCCCAGTTCTCGCCGCTCGGCTTCGAAGAGCAGACCTGCGTGATCTTCGCCGGCACCCAGGGCTACCTGG
ATGCCGTTCCGGTGAACCGCGTCACCGAATACGAAGCCGAACTGCTCAGCTTCCTGCGCTCGCAGCATGCCGACCTGCTC
GGCCTGATCCGCGACACCAAGGACCTTGGCGACGAAGCCAAGGGCAAGCTGGTCGCGGCTCTCGACGCTTTCGCCAAGCA
GTTCGCATAA

Upstream 100 bases:

>100_bases
CGACAGCTCGATCCGCACCCGTCTCAATTCCCTCGCCCAGGCGATGAAGGCCTGACGGACCGCAAGGTTCCAGGCCAAAA
GGTTCCAGGAAGGACTGAAA

Downstream 100 bases:

>100_bases
TGCTGATGCTCGCGTCTATGTCTGTGCTAGCCGCGAGCACTTCAGGTTCGGCGGTGCCATTCTCACTTTTTCAAGAAGTC
TGGACAAAGTGTGTGGTAGC

Product: F0F1 ATP synthase subunit alpha

Products: NA

Alternate protein names: ATP synthase F1 sector subunit alpha; F-ATPase subunit alpha

Number of amino acids: Translated: 509; Mature: 509

Protein sequence:

>509_residues
MEIRAAEISKVIKDQIASFGTEAQVSEVGSVLSVGDGIARIHGLDKVQAGEMVEFSNGVKGMALNLEADNVGVVIFGSDS
EIKEGDVVKRTGTIVDVPVGKGLLGRVVDALGNPIDGKGPIVDATRQRVEVKAPGIIPRKSVHEPVQTGLKAIDALVPVG
RGQRELIIGDRQTGKTAVAIDTFINQKAVNAGTDEGKKLYCIYVAVGQKRSTVAQIVRQLEENGAMEYSIVVAATASEPA
PLQYLAPYTGATMGEFFRDNGMHAVIVYDDLSKQAVAYRQMSLLLRRPPGREAYPGDVFYLHSRLLERAAKMNDENGAGS
LTALPIIETQAGDVSAYIPTNVISITDGQIFLETGLFYQGIRPAINVGLSVSRVGSSAQTKAMKKVAGSIKLELAQYREM
AAFAQFGSDLDASTQKLLNRGARLTELLKQPQFSPLGFEEQTCVIFAGTQGYLDAVPVNRVTEYEAELLSFLRSQHADLL
GLIRDTKDLGDEAKGKLVAALDAFAKQFA

Sequences:

>Translated_509_residues
MEIRAAEISKVIKDQIASFGTEAQVSEVGSVLSVGDGIARIHGLDKVQAGEMVEFSNGVKGMALNLEADNVGVVIFGSDS
EIKEGDVVKRTGTIVDVPVGKGLLGRVVDALGNPIDGKGPIVDATRQRVEVKAPGIIPRKSVHEPVQTGLKAIDALVPVG
RGQRELIIGDRQTGKTAVAIDTFINQKAVNAGTDEGKKLYCIYVAVGQKRSTVAQIVRQLEENGAMEYSIVVAATASEPA
PLQYLAPYTGATMGEFFRDNGMHAVIVYDDLSKQAVAYRQMSLLLRRPPGREAYPGDVFYLHSRLLERAAKMNDENGAGS
LTALPIIETQAGDVSAYIPTNVISITDGQIFLETGLFYQGIRPAINVGLSVSRVGSSAQTKAMKKVAGSIKLELAQYREM
AAFAQFGSDLDASTQKLLNRGARLTELLKQPQFSPLGFEEQTCVIFAGTQGYLDAVPVNRVTEYEAELLSFLRSQHADLL
GLIRDTKDLGDEAKGKLVAALDAFAKQFA
>Mature_509_residues
MEIRAAEISKVIKDQIASFGTEAQVSEVGSVLSVGDGIARIHGLDKVQAGEMVEFSNGVKGMALNLEADNVGVVIFGSDS
EIKEGDVVKRTGTIVDVPVGKGLLGRVVDALGNPIDGKGPIVDATRQRVEVKAPGIIPRKSVHEPVQTGLKAIDALVPVG
RGQRELIIGDRQTGKTAVAIDTFINQKAVNAGTDEGKKLYCIYVAVGQKRSTVAQIVRQLEENGAMEYSIVVAATASEPA
PLQYLAPYTGATMGEFFRDNGMHAVIVYDDLSKQAVAYRQMSLLLRRPPGREAYPGDVFYLHSRLLERAAKMNDENGAGS
LTALPIIETQAGDVSAYIPTNVISITDGQIFLETGLFYQGIRPAINVGLSVSRVGSSAQTKAMKKVAGSIKLELAQYREM
AAFAQFGSDLDASTQKLLNRGARLTELLKQPQFSPLGFEEQTCVIFAGTQGYLDAVPVNRVTEYEAELLSFLRSQHADLL
GLIRDTKDLGDEAKGKLVAALDAFAKQFA

Specific function: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit

COG id: COG0056

COG function: function code C; F0F1-type ATP synthase, alpha subunit

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATPase alpha/beta chains family

Homologues:

Organism=Homo sapiens, GI50345984, Length=503, Percent_Identity=71.9681908548708, Blast_Score=748, Evalue=0.0,
Organism=Homo sapiens, GI4757810, Length=503, Percent_Identity=71.9681908548708, Blast_Score=748, Evalue=0.0,
Organism=Homo sapiens, GI19913428, Length=302, Percent_Identity=29.1390728476821, Blast_Score=118, Evalue=1e-26,
Organism=Homo sapiens, GI19913426, Length=370, Percent_Identity=27.8378378378378, Blast_Score=114, Evalue=1e-25,
Organism=Homo sapiens, GI32189394, Length=379, Percent_Identity=24.2744063324538, Blast_Score=92, Evalue=1e-18,
Organism=Homo sapiens, GI19913424, Length=250, Percent_Identity=26.4, Blast_Score=78, Evalue=2e-14,
Organism=Escherichia coli, GI1790172, Length=515, Percent_Identity=58.252427184466, Blast_Score=596, Evalue=1e-171,
Organism=Escherichia coli, GI1790170, Length=419, Percent_Identity=24.582338902148, Blast_Score=108, Evalue=7e-25,
Organism=Escherichia coli, GI1788251, Length=351, Percent_Identity=26.4957264957265, Blast_Score=100, Evalue=2e-22,
Organism=Caenorhabditis elegans, GI71988063, Length=503, Percent_Identity=71.5705765407555, Blast_Score=741, Evalue=0.0,
Organism=Caenorhabditis elegans, GI71988080, Length=503, Percent_Identity=71.5705765407555, Blast_Score=740, Evalue=0.0,
Organism=Caenorhabditis elegans, GI71988074, Length=503, Percent_Identity=66.0039761431412, Blast_Score=669, Evalue=0.0,
Organism=Caenorhabditis elegans, GI17570191, Length=332, Percent_Identity=29.2168674698795, Blast_Score=120, Evalue=2e-27,
Organism=Caenorhabditis elegans, GI17510931, Length=383, Percent_Identity=27.4151436031332, Blast_Score=114, Evalue=2e-25,
Organism=Caenorhabditis elegans, GI25144756, Length=394, Percent_Identity=24.6192893401015, Blast_Score=98, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI71988068, Length=75, Percent_Identity=54.6666666666667, Blast_Score=92, Evalue=6e-19,
Organism=Caenorhabditis elegans, GI17509265, Length=50, Percent_Identity=64, Blast_Score=77, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17565854, Length=266, Percent_Identity=26.3157894736842, Blast_Score=77, Evalue=2e-14,
Organism=Saccharomyces cerevisiae, GI6319370, Length=502, Percent_Identity=70.9163346613546, Blast_Score=743, Evalue=0.0,
Organism=Saccharomyces cerevisiae, GI6319603, Length=350, Percent_Identity=29.7142857142857, Blast_Score=124, Evalue=2e-29,
Organism=Saccharomyces cerevisiae, GI6322581, Length=379, Percent_Identity=26.1213720316623, Blast_Score=108, Evalue=2e-24,
Organism=Drosophila melanogaster, GI24658560, Length=505, Percent_Identity=69.7029702970297, Blast_Score=724, Evalue=0.0,
Organism=Drosophila melanogaster, GI281361666, Length=334, Percent_Identity=27.8443113772455, Blast_Score=120, Evalue=2e-27,
Organism=Drosophila melanogaster, GI24646341, Length=334, Percent_Identity=27.8443113772455, Blast_Score=120, Evalue=2e-27,
Organism=Drosophila melanogaster, GI17136796, Length=334, Percent_Identity=27.8443113772455, Blast_Score=120, Evalue=2e-27,
Organism=Drosophila melanogaster, GI28574560, Length=410, Percent_Identity=26.0975609756098, Blast_Score=95, Evalue=1e-19,
Organism=Drosophila melanogaster, GI24638766, Length=386, Percent_Identity=24.6113989637306, Blast_Score=94, Evalue=3e-19,
Organism=Drosophila melanogaster, GI20129479, Length=250, Percent_Identity=28, Blast_Score=77, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24583988, Length=267, Percent_Identity=26.2172284644195, Blast_Score=75, Evalue=1e-13,
Organism=Drosophila melanogaster, GI24583986, Length=267, Percent_Identity=26.2172284644195, Blast_Score=75, Evalue=1e-13,
Organism=Drosophila melanogaster, GI24583984, Length=267, Percent_Identity=26.2172284644195, Blast_Score=75, Evalue=1e-13,
Organism=Drosophila melanogaster, GI24583992, Length=267, Percent_Identity=26.2172284644195, Blast_Score=75, Evalue=1e-13,

Paralogues:

None

Copy number: 9,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): ATPA_NOVAD (Q2G5N7)

Other databases:

- EMBL:   CP000248
- RefSeq:   YP_497670.1
- ProteinModelPortal:   Q2G5N7
- SMR:   Q2G5N7
- STRING:   Q2G5N7
- GeneID:   3916719
- GenomeReviews:   CP000248_GR
- KEGG:   nar:Saro_2400
- NMPDR:   fig|48935.1.peg.2419
- eggNOG:   COG0056
- HOGENOM:   HBG565875
- OMA:   GSDRDIK
- PhylomeDB:   Q2G5N7
- ProtClustDB:   PRK09281
- BioCyc:   NARO279238:SARO_2400-MONOMER
- HAMAP:   MF_01346
- InterPro:   IPR020003
- InterPro:   IPR000194
- InterPro:   IPR005294
- InterPro:   IPR017458
- InterPro:   IPR018118
- InterPro:   IPR000793
- InterPro:   IPR004100
- PANTHER:   PTHR15184:SF3
- TIGRFAMs:   TIGR00962

Pfam domain/function: PF00006 ATP-synt_ab; PF00306 ATP-synt_ab_C; PF02874 ATP-synt_ab_N; SSF47917 ATPase_a/b_C; SSF50615 ATPase_a/b_N

EC number: =3.6.3.14

Molecular weight: Translated: 54570; Mature: 54570

Theoretical pI: Translated: 5.60; Mature: 5.60

Prosite motif: PS00152 ATPASE_ALPHA_BETA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEIRAAEISKVIKDQIASFGTEAQVSEVGSVLSVGDGIARIHGLDKVQAGEMVEFSNGVK
CCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCHHHHCCCCCCCCCCEEECCCCCC
GMALNLEADNVGVVIFGSDSEIKEGDVVKRTGTIVDVPVGKGLLGRVVDALGNPIDGKGP
EEEEEEECCCEEEEEECCCCCCCCCCEEEECCCEEEECCCCCHHHHHHHHHCCCCCCCCC
IVDATRQRVEVKAPGIIPRKSVHEPVQTGLKAIDALVPVGRGQRELIIGDRQTGKTAVAI
EECCCHHEEEEECCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCEEEEE
DTFINQKAVNAGTDEGKKLYCIYVAVGQKRSTVAQIVRQLEENGAMEYSIVVAATASEPA
HHHHHHHHCCCCCCCCCEEEEEEEEECCCHHHHHHHHHHHHHCCCEEEEEEEEEECCCCC
PLQYLAPYTGATMGEFFRDNGMHAVIVYDDLSKQAVAYRQMSLLLRRPPGREAYPGDVFY
CCEEECCCCCCHHHHHHHCCCCEEEEEECCCCHHHHHHHHHHHHHCCCCCCCCCCCHHHH
LHSRLLERAAKMNDENGAGSLTALPIIETQAGDVSAYIPTNVISITDGQIFLETGLFYQG
HHHHHHHHHHHCCCCCCCCCEEEEEEEECCCCCEEEECCCCEEEEECCEEEEECCCHHHC
IRPAINVGLSVSRVGSSAQTKAMKKVAGSIKLELAQYREMAAFAQFGSDLDASTQKLLNR
CCHHHHCCEEHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHC
GARLTELLKQPQFSPLGFEEQTCVIFAGTQGYLDAVPVNRVTEYEAELLSFLRSQHADLL
CHHHHHHHHCCCCCCCCCCCCEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHCHHHH
GLIRDTKDLGDEAKGKLVAALDAFAKQFA
HHHHHHHHCCCHHCCHHHHHHHHHHHHCC
>Mature Secondary Structure
MEIRAAEISKVIKDQIASFGTEAQVSEVGSVLSVGDGIARIHGLDKVQAGEMVEFSNGVK
CCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCHHHHCCCCCCCCCCEEECCCCCC
GMALNLEADNVGVVIFGSDSEIKEGDVVKRTGTIVDVPVGKGLLGRVVDALGNPIDGKGP
EEEEEEECCCEEEEEECCCCCCCCCCEEEECCCEEEECCCCCHHHHHHHHHCCCCCCCCC
IVDATRQRVEVKAPGIIPRKSVHEPVQTGLKAIDALVPVGRGQRELIIGDRQTGKTAVAI
EECCCHHEEEEECCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCEEEEE
DTFINQKAVNAGTDEGKKLYCIYVAVGQKRSTVAQIVRQLEENGAMEYSIVVAATASEPA
HHHHHHHHCCCCCCCCCEEEEEEEEECCCHHHHHHHHHHHHHCCCEEEEEEEEEECCCCC
PLQYLAPYTGATMGEFFRDNGMHAVIVYDDLSKQAVAYRQMSLLLRRPPGREAYPGDVFY
CCEEECCCCCCHHHHHHHCCCCEEEEEECCCCHHHHHHHHHHHHHCCCCCCCCCCCHHHH
LHSRLLERAAKMNDENGAGSLTALPIIETQAGDVSAYIPTNVISITDGQIFLETGLFYQG
HHHHHHHHHHHCCCCCCCCCEEEEEEEECCCCCEEEECCCCEEEEECCEEEEECCCHHHC
IRPAINVGLSVSRVGSSAQTKAMKKVAGSIKLELAQYREMAAFAQFGSDLDASTQKLLNR
CCHHHHCCEEHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHC
GARLTELLKQPQFSPLGFEEQTCVIFAGTQGYLDAVPVNRVTEYEAELLSFLRSQHADLL
CHHHHHHHHCCCCCCCCCCCCEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHCHHHH
GLIRDTKDLGDEAKGKLVAALDAFAKQFA
HHHHHHHHCCCHHCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA