Click here to switch to the map view.

The map label for this gene is atpH [H]

Identifier: 87200412

GI number: 87200412

Start: 2566457

End: 2567029

Strand: Direct

Name: atpH [H]

Synonym: Saro_2399

Alternate gene names: 87200412

Gene position: 2566457-2567029 (Clockwise)

Preceding gene: 87200411

Following gene: 87200413

Centisome position: 72.06

GC content: 64.4

Gene sequence:

>573_bases
ATGAAGGAACTTCGGCGCGTGGAGATTTCCAGCGGCATTACGGCCAGCCTGTCAGGGCGCTACGCCTCGGCATTGTTCGA
TCTGGCGAATGATCAGGGCTTCGTTTCGGCCGTGGAAGGCGATCTCGAGAAGCTCGACGCCGCGCTGCGCGAATCGGCCG
ACCTGAAGGGCCTCATCAACAACCCCCAGCTTGGCCGCGACGAAGCCGGCCGCGCGATGGATGCGGTTGCGGGCCTGCTT
GGCCTTGGTGAGCTTACGAAGAAGTTCGTCGGCGTCCTCGCCGCCAACCGCCGCCTTTCGGCCCTCCCCGACGTGATCCG
CGCCTTCGGCCAGATCGCCGCCGCCCAGCGTGGCGAAGTCAGCGCCGAAGTGACCAGCGCCCATGCGCTCGACGATGCCC
AGGTTGCCGCCCTCACCGAAAAGCTGAAGGCCCGTACCGGCAAGTCGATCAAGCTCAAGACCAGTGTCGATCCCGAAATC
CTCGGTGGCCTCGTCGTGAAAATCGGCAGCCAGATGATCGACAGCTCGATCCGCACCCGTCTCAATTCCCTCGCCCAGGC
GATGAAGGCCTGA

Upstream 100 bases:

>100_bases
TCGCATCTTGTCATAACGGCCCGACGTTGCTAGGCGCGCCCCGTCTGCGGGCCACCGGGTGTTCACCACACGGACTTGGT
CCGCTTCGGCTTATCCTTGG

Downstream 100 bases:

>100_bases
CGGACCGCAAGGTTCCAGGCCAAAAGGTTCCAGGAAGGACTGAAAATGGAAATCCGCGCCGCTGAAATCTCGAAGGTCAT
CAAGGACCAGATCGCCAGCT

Product: F0F1 ATP synthase subunit delta

Products: ADP; phosphate; H+

Alternate protein names: ATP synthase F(1) sector subunit delta; F-type ATPase subunit delta; F-ATPase subunit delta [H]

Number of amino acids: Translated: 190; Mature: 190

Protein sequence:

>190_residues
MKELRRVEISSGITASLSGRYASALFDLANDQGFVSAVEGDLEKLDAALRESADLKGLINNPQLGRDEAGRAMDAVAGLL
GLGELTKKFVGVLAANRRLSALPDVIRAFGQIAAAQRGEVSAEVTSAHALDDAQVAALTEKLKARTGKSIKLKTSVDPEI
LGGLVVKIGSQMIDSSIRTRLNSLAQAMKA

Sequences:

>Translated_190_residues
MKELRRVEISSGITASLSGRYASALFDLANDQGFVSAVEGDLEKLDAALRESADLKGLINNPQLGRDEAGRAMDAVAGLL
GLGELTKKFVGVLAANRRLSALPDVIRAFGQIAAAQRGEVSAEVTSAHALDDAQVAALTEKLKARTGKSIKLKTSVDPEI
LGGLVVKIGSQMIDSSIRTRLNSLAQAMKA
>Mature_190_residues
MKELRRVEISSGITASLSGRYASALFDLANDQGFVSAVEGDLEKLDAALRESADLKGLINNPQLGRDEAGRAMDAVAGLL
GLGELTKKFVGVLAANRRLSALPDVIRAFGQIAAAQRGEVSAEVTSAHALDDAQVAALTEKLKARTGKSIKLKTSVDPEI
LGGLVVKIGSQMIDSSIRTRLNSLAQAMKA

Specific function: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction [H]

COG id: COG0712

COG function: function code C; F0F1-type ATP synthase, delta subunit (mitochondrial oligomycin sensitivity protein)

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATPase delta chain family [H]

Homologues:

Organism=Homo sapiens, GI4502303, Length=175, Percent_Identity=33.1428571428571, Blast_Score=104, Evalue=6e-23,
Organism=Escherichia coli, GI1790173, Length=170, Percent_Identity=28.8235294117647, Blast_Score=73, Evalue=9e-15,
Organism=Caenorhabditis elegans, GI71984710, Length=174, Percent_Identity=32.7586206896552, Blast_Score=102, Evalue=1e-22,
Organism=Caenorhabditis elegans, GI71984717, Length=174, Percent_Identity=32.7586206896552, Blast_Score=102, Evalue=1e-22,
Organism=Saccharomyces cerevisiae, GI6320504, Length=178, Percent_Identity=29.7752808988764, Blast_Score=80, Evalue=3e-16,
Organism=Drosophila melanogaster, GI24647054, Length=167, Percent_Identity=37.125748502994, Blast_Score=103, Evalue=1e-22,
Organism=Drosophila melanogaster, GI24647056, Length=98, Percent_Identity=43.8775510204082, Blast_Score=76, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000711
- InterPro:   IPR020781 [H]

Pfam domain/function: PF00213 OSCP [H]

EC number: 3.6.3.14

Molecular weight: Translated: 19942; Mature: 19942

Theoretical pI: Translated: 9.65; Mature: 9.65

Prosite motif: PS00389 ATPASE_DELTA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKELRRVEISSGITASLSGRYASALFDLANDQGFVSAVEGDLEKLDAALRESADLKGLIN
CCCHHHHHHCCCCEEHHCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCC
NPQLGRDEAGRAMDAVAGLLGLGELTKKFVGVLAANRRLSALPDVIRAFGQIAAAQRGEV
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCC
SAEVTSAHALDDAQVAALTEKLKARTGKSIKLKTSVDPEILGGLVVKIGSQMIDSSIRTR
HHHHHHHHHCCHHHHHHHHHHHHHHCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHH
LNSLAQAMKA
HHHHHHHHCC
>Mature Secondary Structure
MKELRRVEISSGITASLSGRYASALFDLANDQGFVSAVEGDLEKLDAALRESADLKGLIN
CCCHHHHHHCCCCEEHHCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCC
NPQLGRDEAGRAMDAVAGLLGLGELTKKFVGVLAANRRLSALPDVIRAFGQIAAAQRGEV
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCC
SAEVTSAHALDDAQVAALTEKLKARTGKSIKLKTSVDPEILGGLVVKIGSQMIDSSIRTR
HHHHHHHHHCCHHHHHHHHHHHHHHCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHH
LNSLAQAMKA
HHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: Borate; diphosphate; HCO3- [C]

Metal ions: Co2+; Fe2+; Mn2+; Zn2+ [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; H2O; H+

Specific reaction: ATP + H2O + H+(in) = ADP + phosphate + H+(out)

General reaction: Phosphorous acid anhydride hydrolysis [C]

Inhibitor: Ca2+; CN-; Efrapeptin; Ethidiumbromide; Guanidines analogs; Oligomycin; Quercetin; Trialkyl tin derivatives; Venturicidin [C]

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA