Click here to switch to the map view.

The map label for this gene is vvpD [H]

Identifier: 87200319

GI number: 87200319

Start: 2445429

End: 2446217

Strand: Reverse

Name: vvpD [H]

Synonym: Saro_2305

Alternate gene names: 87200319

Gene position: 2446217-2445429 (Counterclockwise)

Preceding gene: 87200321

Following gene: 87200318

Centisome position: 68.68

GC content: 66.92

Gene sequence:

>789_bases
ATGCTTGGTGCGGCTTATCTATCCGCTTTCCCGCTCGGACTTCTCGTCTCCGGGGCGGCAGTTCTCGGCGCGGTGATCGG
CAGTTTCCTGGGCGCGTCGCTGGTGCGCCTTCCCGAAGGGCGCTCGGTCGTGAGCGGGCGTTCGGCCTGCGACGGGTGCG
GCAAGGCGTTGACAATCGCCGAGCTGGTTCCGGTGCTGTCGTGGCTCGTGCAGCGGGGCAAATGCCGCGCCTGCGGCGTC
CGGATCGGCGGATGGCAACTGGCCTGCGAGCTGGGTGGGGGCGCCGTCGGCGTCGGATCGGTCCTGCTGGCGAGGGAAGG
CCTTGTGCTGGCCGGAATGTTGTTTGGCTGGCAACTGCTACTGCTCGCACTGCTCGATCTCAGGCACCTGTGGCTGCCGC
GCGTTCTTGTCGGATTGCTGGCAGGGACGGGGCTTGCAGTCGTGTTCGCCCGCGCATGGAGCATCCAGGGGATGGACCCG
GTGCTGGTTTCGCTGGGAGGAGGAGCGCTGGGTTACCTCATGCTGTGGGCCATCGCACGTTTCTATCTGAAGGCGCGGGG
GCGGGAAGGCATGGGCGCGGGCGACCCTCCGCTGCTTGGCGCCATAGGCATCTGGGTCGGGCCGCTGGGCGTGGTGGAGG
TCATGCTGGGGGCCAGCATTCTCGGGATCGCGGTGGCTATTGTCATGCTTGTAAGCAGGCGTAACATTGCCGCCGACACG
GCCTTGCCGCTGGGAACCTGCCTTGCCGCTACGGCATGGCCGATCTTCCTGTTGCAGGGCCTCGGATAG

Upstream 100 bases:

>100_bases
TCCCTATGGAATCGGTGCTGATGGCGCCGCGCGGCGCCGGCTGACCTGTAACTTTGTAGTGTTGCAGCGCAGCGAAAGCA
AACGGGGCAGGGAGGGGCAC

Downstream 100 bases:

>100_bases
GCGATTCGGGGGACAAGCAATGAAGGACACGACGCGGGGCGAGATGCTGGCGCAGCTCGAGCGGCAGAAGGCGGCATTCA
CCCAGGCGCGCCCCGAACCC

Product: type 4 prepilin peptidase

Products: NA

Alternate protein names: Leader peptidase; Prepilin peptidase; N-methyltransferase [H]

Number of amino acids: Translated: 262; Mature: 262

Protein sequence:

>262_residues
MLGAAYLSAFPLGLLVSGAAVLGAVIGSFLGASLVRLPEGRSVVSGRSACDGCGKALTIAELVPVLSWLVQRGKCRACGV
RIGGWQLACELGGGAVGVGSVLLAREGLVLAGMLFGWQLLLLALLDLRHLWLPRVLVGLLAGTGLAVVFARAWSIQGMDP
VLVSLGGGALGYLMLWAIARFYLKARGREGMGAGDPPLLGAIGIWVGPLGVVEVMLGASILGIAVAIVMLVSRRNIAADT
ALPLGTCLAATAWPIFLLQGLG

Sequences:

>Translated_262_residues
MLGAAYLSAFPLGLLVSGAAVLGAVIGSFLGASLVRLPEGRSVVSGRSACDGCGKALTIAELVPVLSWLVQRGKCRACGV
RIGGWQLACELGGGAVGVGSVLLAREGLVLAGMLFGWQLLLLALLDLRHLWLPRVLVGLLAGTGLAVVFARAWSIQGMDP
VLVSLGGGALGYLMLWAIARFYLKARGREGMGAGDPPLLGAIGIWVGPLGVVEVMLGASILGIAVAIVMLVSRRNIAADT
ALPLGTCLAATAWPIFLLQGLG
>Mature_262_residues
MLGAAYLSAFPLGLLVSGAAVLGAVIGSFLGASLVRLPEGRSVVSGRSACDGCGKALTIAELVPVLSWLVQRGKCRACGV
RIGGWQLACELGGGAVGVGSVLLAREGLVLAGMLFGWQLLLLALLDLRHLWLPRVLVGLLAGTGLAVVFARAWSIQGMDP
VLVSLGGGALGYLMLWAIARFYLKARGREGMGAGDPPLLGAIGIWVGPLGVVEVMLGASILGIAVAIVMLVSRRNIAADT
ALPLGTCLAATAWPIFLLQGLG

Specific function: Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue [H]

COG id: COG1989

COG function: function code NOU; Type II secretory pathway, prepilin signal peptidase PulO and related peptidases

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase A24 family [H]

Homologues:

Organism=Escherichia coli, GI87082194, Length=250, Percent_Identity=31.6, Blast_Score=84, Evalue=8e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010627
- InterPro:   IPR014032
- InterPro:   IPR000045 [H]

Pfam domain/function: PF06750 DiS_P_DiS; PF01478 Peptidase_A24 [H]

EC number: =3.4.23.43 [H]

Molecular weight: Translated: 26743; Mature: 26743

Theoretical pI: Translated: 9.46; Mature: 9.46

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLGAAYLSAFPLGLLVSGAAVLGAVIGSFLGASLVRLPEGRSVVSGRSACDGCGKALTIA
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHCCCHHHHHHHHHHHHH
ELVPVLSWLVQRGKCRACGVRIGGWQLACELGGGAVGVGSVLLAREGLVLAGMLFGWQLL
HHHHHHHHHHHCCCCCCCCEEECCEEEEEECCCCHHHHHHHHHHHCCHHHHHHHHHHHHH
LLALLDLRHLWLPRVLVGLLAGTGLAVVFARAWSIQGMDPVLVSLGGGALGYLMLWAIAR
HHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCHHHEECCCHHHHHHHHHHHHH
FYLKARGREGMGAGDPPLLGAIGIWVGPLGVVEVMLGASILGIAVAIVMLVSRRNIAADT
HHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHC
ALPLGTCLAATAWPIFLLQGLG
CCHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MLGAAYLSAFPLGLLVSGAAVLGAVIGSFLGASLVRLPEGRSVVSGRSACDGCGKALTIA
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHCCCHHHHHHHHHHHHH
ELVPVLSWLVQRGKCRACGVRIGGWQLACELGGGAVGVGSVLLAREGLVLAGMLFGWQLL
HHHHHHHHHHHCCCCCCCCEEECCEEEEEECCCCHHHHHHHHHHHCCHHHHHHHHHHHHH
LLALLDLRHLWLPRVLVGLLAGTGLAVVFARAWSIQGMDPVLVSLGGGALGYLMLWAIAR
HHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCHHHEECCCHHHHHHHHHHHHH
FYLKARGREGMGAGDPPLLGAIGIWVGPLGVVEVMLGASILGIAVAIVMLVSRRNIAADT
HHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHC
ALPLGTCLAATAWPIFLLQGLG
CCHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9826339 [H]