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The map label for this gene is nuoG [H]

Identifier: 87200308

GI number: 87200308

Start: 2435747

End: 2437756

Strand: Reverse

Name: nuoG [H]

Synonym: Saro_2294

Alternate gene names: 87200308

Gene position: 2437756-2435747 (Counterclockwise)

Preceding gene: 87200309

Following gene: 87200307

Centisome position: 68.45

GC content: 64.98

Gene sequence:

>2010_bases
ATGCCTAAGGTTAAGGTAGACGGCGTAGAACTCGAAGTTCCGGCAGGCGCCACCGTCCTGCAGGCGTGCGAGCTGGCCGG
CAAGGAAATCCCGCGCTTCTGCTATCACGAACGGCTGAGCATTGCCGGCAATTGCCGCATGTGCCTGGTCGAAGTGAAGC
CCGGACCGCCGAAGCCGCAGGCTTCCTGCGCGCTCCCGGCGACCGAGGGCCAGGAAATCCGCACGGACTCCGAGATGGTC
AAGAAGGCGCGCGAAGGGGTGATGGAGTTCCTCCTCATCAACCACCCGCTCGACTGCCCGATCTGCGACCAGGGCGGTGA
ATGCGATCTGCAAGACCAGTCGGTCGCCTATGGCCGCGGTGCCTCGCGCTATCACGAAAACAAGCGCGCGGTGACCGAGA
AGTACATGGGCCCGCTCATCAAGACGACGATGACGCGCTGCATTCATTGCACCCGCTGCGTGCGTTTCTCGGAAGAGGTC
GCGGGCGTGGACGAGATCGGTGCGCTTTATCGCGGCGAGACGATGCAGATTTCGACCTATCTCGAGAAGGCTGCGGCGCA
CGAACTTTCGGCCAACGTGATCGACCTCTGCCCGGTCGGTGCGCTGACTTCGCGCCCCTATGCGTTCGAAGCGCGTCCGT
GGGAGCTGAAGAAGACGCTGTCGATCGACGTTTCGGATGCTCTGGGTTCGAACATCCGGCTCGACAGCCGTGGCCGCGAG
GTGCTGCGCATCCTGCCGCGCGTGAACGACGACGTGAACGAGGAATGGCTGTCCGACCGTGGCCGCTACATGGTCGACGG
GCTGACCCGCCGCCGCCTCGACAAGCCTTGGCTGCGCCGTGACGGCAAGCTGGTCGCAGCGACCTGGGCCGAAGCGTTCG
AAGCCGTTGCGAAGGTCAACCCGGGTTCGTCTGTCGCGGTCATCGCTGGCGATCTGGTCGATTGCGAGACGATGTTCGCG
GCAAAGAAGCTGGCCGGCGCACTGGGATCGTCCCTGCTCGAAGGCCGCCAGACCGGTTTGGCTTACGACACGTCGAACCT
CACCGCTGTGAACTTCAACTCGACGCTGGCTGGCATCGAGGACGCGGACGCCGTTCTGATCGTCGGTTCGATGATTCGTG
ACGAGGCTCCTCTGCTCAACACCCGCCTGCGCAAGGCGGCGAAGAAGGGCGCGAAGGTGTTCATCGTCGGCCCGCACTGG
GACCCGACCTATCCGGCGACGTTTCTGGGCGACGATCTGGCAGTGCTTGGAAACCTGCCGGCCGAAGTCAGCGATGCGTT
CGGTGCGGCACAGAAGCCGGCGATCATTGTCGGCGGCGCGGCGCTGGGCAAGGGTGCGCTGGCCGCGGGCTTGGCCTTCG
CCGAAAAGTTCAACCTCGTCCGTGAGGGCTGGAACGGCTTCAACGTCGTCCACATGGCGGCGAGCCGCATGGGTGGCCTG
ATGCTCGGCTATGCGCAGAAGGGTGGCATTGCCGACCTCGTTGCGGCCAAGCCGAAGATGGTGATCTCGCTCGGTGCCGA
CGAAGTGGACTTCACCAGGTTCGCGGGCAGCATGATCGTCCACATCGGCCATCATGGTGACAAGGCGGCGCACGCCGCCG
ACGTGATCCTGCCGGCCGCCGCGTTCAGCGAGAAGGACGGCACCTACGTCAACACCGAAGGCCGCGTGCAGTATGCGGAG
AAAGCCGTGTTCGCGCCGGGCGATGCCCGCGAGGACTGGACGATCTTGCGCGCCATGGCCGATGCGCTGGGAGTTTCGGT
CGGCTTCGACAGCTTCGAGCAGCTTCGCGCCGCCATGGTTGCCGAAGTTCCGGCACTGGGGTTGGAAGGTCTGGCCGATT
ACGGTGCGCTGCCTGCCGCGTCTGCCGACGTGAAGGCCGAGGGCGTGATCGCGGGCTATCCGATCAAGGACCGCTACCTG
ACCAACGCCATCGCCCGCTCCAGCCCGACGCTGCAGCGCTGCTCGGCGGAACTGCTCCACGGTGAAAGCTTCGCGGAGGC
CGCGGAATGA

Upstream 100 bases:

>100_bases
CGTCACCCTGAACTTGTTTCAGGGTCCATCTCTCGTCCCGCACCGTCCGTGTTCGTTGCGGGATGGATGCTGAAACAAGT
TCAGCATGACGGAGTGTTTC

Downstream 100 bases:

>100_bases
GCATGCGCACCGCTATCCAAACAAGCCACGTCACCCTGAACTTGTTTCAGGGTCCATGGTGCCCCACAGCACGAACCGTG
CAGGTTGAGGGATGGATGCT

Product: NADH dehydrogenase subunit G

Products: NA

Alternate protein names: NADH dehydrogenase I subunit G; NDH-1 subunit G [H]

Number of amino acids: Translated: 669; Mature: 668

Protein sequence:

>669_residues
MPKVKVDGVELEVPAGATVLQACELAGKEIPRFCYHERLSIAGNCRMCLVEVKPGPPKPQASCALPATEGQEIRTDSEMV
KKAREGVMEFLLINHPLDCPICDQGGECDLQDQSVAYGRGASRYHENKRAVTEKYMGPLIKTTMTRCIHCTRCVRFSEEV
AGVDEIGALYRGETMQISTYLEKAAAHELSANVIDLCPVGALTSRPYAFEARPWELKKTLSIDVSDALGSNIRLDSRGRE
VLRILPRVNDDVNEEWLSDRGRYMVDGLTRRRLDKPWLRRDGKLVAATWAEAFEAVAKVNPGSSVAVIAGDLVDCETMFA
AKKLAGALGSSLLEGRQTGLAYDTSNLTAVNFNSTLAGIEDADAVLIVGSMIRDEAPLLNTRLRKAAKKGAKVFIVGPHW
DPTYPATFLGDDLAVLGNLPAEVSDAFGAAQKPAIIVGGAALGKGALAAGLAFAEKFNLVREGWNGFNVVHMAASRMGGL
MLGYAQKGGIADLVAAKPKMVISLGADEVDFTRFAGSMIVHIGHHGDKAAHAADVILPAAAFSEKDGTYVNTEGRVQYAE
KAVFAPGDAREDWTILRAMADALGVSVGFDSFEQLRAAMVAEVPALGLEGLADYGALPAASADVKAEGVIAGYPIKDRYL
TNAIARSSPTLQRCSAELLHGESFAEAAE

Sequences:

>Translated_669_residues
MPKVKVDGVELEVPAGATVLQACELAGKEIPRFCYHERLSIAGNCRMCLVEVKPGPPKPQASCALPATEGQEIRTDSEMV
KKAREGVMEFLLINHPLDCPICDQGGECDLQDQSVAYGRGASRYHENKRAVTEKYMGPLIKTTMTRCIHCTRCVRFSEEV
AGVDEIGALYRGETMQISTYLEKAAAHELSANVIDLCPVGALTSRPYAFEARPWELKKTLSIDVSDALGSNIRLDSRGRE
VLRILPRVNDDVNEEWLSDRGRYMVDGLTRRRLDKPWLRRDGKLVAATWAEAFEAVAKVNPGSSVAVIAGDLVDCETMFA
AKKLAGALGSSLLEGRQTGLAYDTSNLTAVNFNSTLAGIEDADAVLIVGSMIRDEAPLLNTRLRKAAKKGAKVFIVGPHW
DPTYPATFLGDDLAVLGNLPAEVSDAFGAAQKPAIIVGGAALGKGALAAGLAFAEKFNLVREGWNGFNVVHMAASRMGGL
MLGYAQKGGIADLVAAKPKMVISLGADEVDFTRFAGSMIVHIGHHGDKAAHAADVILPAAAFSEKDGTYVNTEGRVQYAE
KAVFAPGDAREDWTILRAMADALGVSVGFDSFEQLRAAMVAEVPALGLEGLADYGALPAASADVKAEGVIAGYPIKDRYL
TNAIARSSPTLQRCSAELLHGESFAEAAE
>Mature_668_residues
PKVKVDGVELEVPAGATVLQACELAGKEIPRFCYHERLSIAGNCRMCLVEVKPGPPKPQASCALPATEGQEIRTDSEMVK
KAREGVMEFLLINHPLDCPICDQGGECDLQDQSVAYGRGASRYHENKRAVTEKYMGPLIKTTMTRCIHCTRCVRFSEEVA
GVDEIGALYRGETMQISTYLEKAAAHELSANVIDLCPVGALTSRPYAFEARPWELKKTLSIDVSDALGSNIRLDSRGREV
LRILPRVNDDVNEEWLSDRGRYMVDGLTRRRLDKPWLRRDGKLVAATWAEAFEAVAKVNPGSSVAVIAGDLVDCETMFAA
KKLAGALGSSLLEGRQTGLAYDTSNLTAVNFNSTLAGIEDADAVLIVGSMIRDEAPLLNTRLRKAAKKGAKVFIVGPHWD
PTYPATFLGDDLAVLGNLPAEVSDAFGAAQKPAIIVGGAALGKGALAAGLAFAEKFNLVREGWNGFNVVHMAASRMGGLM
LGYAQKGGIADLVAAKPKMVISLGADEVDFTRFAGSMIVHIGHHGDKAAHAADVILPAAAFSEKDGTYVNTEGRVQYAEK
AVFAPGDAREDWTILRAMADALGVSVGFDSFEQLRAAMVAEVPALGLEGLADYGALPAASADVKAEGVIAGYPIKDRYLT
NAIARSSPTLQRCSAELLHGESFAEAAE

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cyto

COG id: COG1034

COG function: function code C; NADH dehydrogenase/NADH:ubiquinone oxidoreductase 75 kD subunit (chain G)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 2Fe-2S ferredoxin-type domain [H]

Homologues:

Organism=Homo sapiens, GI33519475, Length=694, Percent_Identity=46.5417867435158, Blast_Score=586, Evalue=1e-167,
Organism=Escherichia coli, GI145693161, Length=708, Percent_Identity=26.8361581920904, Blast_Score=215, Evalue=7e-57,
Organism=Caenorhabditis elegans, GI17565758, Length=699, Percent_Identity=44.7782546494993, Blast_Score=533, Evalue=1e-151,
Organism=Caenorhabditis elegans, GI32566231, Length=578, Percent_Identity=47.923875432526, Blast_Score=494, Evalue=1e-140,
Organism=Caenorhabditis elegans, GI193209088, Length=252, Percent_Identity=61.1111111111111, Blast_Score=327, Evalue=1e-89,
Organism=Drosophila melanogaster, GI24640559, Length=673, Percent_Identity=48.5884101040119, Blast_Score=594, Evalue=1e-170,
Organism=Drosophila melanogaster, GI24640557, Length=673, Percent_Identity=48.5884101040119, Blast_Score=594, Evalue=1e-170,

Paralogues:

None

Copy number: 60 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012675
- InterPro:   IPR001041
- InterPro:   IPR006656
- InterPro:   IPR000283
- InterPro:   IPR010228
- InterPro:   IPR019574
- InterPro:   IPR015405 [H]

Pfam domain/function: PF09326 DUF1982; PF00111 Fer2; PF00384 Molybdopterin; PF10588 NADH-G_4Fe-4S_3 [H]

EC number: =1.6.99.5 [H]

Molecular weight: Translated: 71553; Mature: 71421

Theoretical pI: Translated: 5.46; Mature: 5.46

Prosite motif: PS00013 PROKAR_LIPOPROTEIN ; PS00641 COMPLEX1_75K_1 ; PS00642 COMPLEX1_75K_2 ; PS00643 COMPLEX1_75K_3 ; PS51085 2FE2S_FER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPKVKVDGVELEVPAGATVLQACELAGKEIPRFCYHERLSIAGNCRMCLVEVKPGPPKPQ
CCCEEECCEEEECCCCHHHHHHHHHHHHHCHHHHHHHHHCCCCCCEEEEEEECCCCCCCC
ASCALPATEGQEIRTDSEMVKKAREGVMEFLLINHPLDCPICDQGGECDLQDQSVAYGRG
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCC
ASRYHENKRAVTEKYMGPLIKTTMTRCIHCTRCVRFSEEVAGVDEIGALYRGETMQISTY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCEEHHHH
LEKAAAHELSANVIDLCPVGALTSRPYAFEARPWELKKTLSIDVSDALGSNIRLDSRGRE
HHHHHHHHHCCCEEEECCCCCCCCCCEEECCCCCEEEEEEEEEEHHHCCCCCEECCCCHH
VLRILPRVNDDVNEEWLSDRGRYMVDGLTRRRLDKPWLRRDGKLVAATWAEAFEAVAKVN
HHHHHHCCCCCCCHHHHHCCCCEEEHHHHHHHCCCHHHHCCCCEEEHHHHHHHHHHHHCC
PGSSVAVIAGDLVDCETMFAAKKLAGALGSSLLEGRQTGLAYDTSNLTAVNFNSTLAGIE
CCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCEEEEECCCCCCCCC
DADAVLIVGSMIRDEAPLLNTRLRKAAKKGAKVFIVGPHWDPTYPATFLGDDLAVLGNLP
CCCEEEEEHHHHHCCCHHHHHHHHHHHHCCCEEEEECCCCCCCCCHHHCCCCHHHHCCCC
AEVSDAFGAAQKPAIIVGGAALGKGALAAGLAFAEKFNLVREGWNGFNVVHMAASRMGGL
HHHHHHHCCCCCCEEEEECCHHCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCE
MLGYAQKGGIADLVAAKPKMVISLGADEVDFTRFAGSMIVHIGHHGDKAAHAADVILPAA
EEEECCCCCCHHHHHCCCCEEEEECCCCHHHHHHCCEEEEEEECCCCHHHHHHHHHEEHH
AFSEKDGTYVNTEGRVQYAEKAVFAPGDAREDWTILRAMADALGVSVGFDSFEQLRAAMV
HCCCCCCCEECCCCCEEEHHHEEECCCCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHH
AEVPALGLEGLADYGALPAASADVKAEGVIAGYPIKDRYLTNAIARSSPTLQRCSAELLH
HHCCCCCHHHHHHCCCCCCCCCCCCCCCEEECCCCCHHHHHHHHHCCCCHHHHHHHHHHC
GESFAEAAE
CCHHHHHCC
>Mature Secondary Structure 
PKVKVDGVELEVPAGATVLQACELAGKEIPRFCYHERLSIAGNCRMCLVEVKPGPPKPQ
CCEEECCEEEECCCCHHHHHHHHHHHHHCHHHHHHHHHCCCCCCEEEEEEECCCCCCCC
ASCALPATEGQEIRTDSEMVKKAREGVMEFLLINHPLDCPICDQGGECDLQDQSVAYGRG
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCC
ASRYHENKRAVTEKYMGPLIKTTMTRCIHCTRCVRFSEEVAGVDEIGALYRGETMQISTY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCEEHHHH
LEKAAAHELSANVIDLCPVGALTSRPYAFEARPWELKKTLSIDVSDALGSNIRLDSRGRE
HHHHHHHHHCCCEEEECCCCCCCCCCEEECCCCCEEEEEEEEEEHHHCCCCCEECCCCHH
VLRILPRVNDDVNEEWLSDRGRYMVDGLTRRRLDKPWLRRDGKLVAATWAEAFEAVAKVN
HHHHHHCCCCCCCHHHHHCCCCEEEHHHHHHHCCCHHHHCCCCEEEHHHHHHHHHHHHCC
PGSSVAVIAGDLVDCETMFAAKKLAGALGSSLLEGRQTGLAYDTSNLTAVNFNSTLAGIE
CCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCEEEEECCCCCCCCC
DADAVLIVGSMIRDEAPLLNTRLRKAAKKGAKVFIVGPHWDPTYPATFLGDDLAVLGNLP
CCCEEEEEHHHHHCCCHHHHHHHHHHHHCCCEEEEECCCCCCCCCHHHCCCCHHHHCCCC
AEVSDAFGAAQKPAIIVGGAALGKGALAAGLAFAEKFNLVREGWNGFNVVHMAASRMGGL
HHHHHHHCCCCCCEEEEECCHHCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCE
MLGYAQKGGIADLVAAKPKMVISLGADEVDFTRFAGSMIVHIGHHGDKAAHAADVILPAA
EEEECCCCCCHHHHHCCCCEEEEECCCCHHHHHHCCEEEEEEECCCCHHHHHHHHHEEHH
AFSEKDGTYVNTEGRVQYAEKAVFAPGDAREDWTILRAMADALGVSVGFDSFEQLRAAMV
HCCCCCCCEECCCCCEEEHHHEEECCCCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHH
AEVPALGLEGLADYGALPAASADVKAEGVIAGYPIKDRYLTNAIARSSPTLQRCSAELLH
HHCCCCCHHHHHHCCCCCCCCCCCCCCCEEECCCCCHHHHHHHHHCCCCHHHHHHHHHHC
GESFAEAAE
CCHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9823893 [H]