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The map label for this gene is nuoI [H]

Identifier: 87200306

GI number: 87200306

Start: 2434082

End: 2434567

Strand: Reverse

Name: nuoI [H]

Synonym: Saro_2292

Alternate gene names: 87200306

Gene position: 2434567-2434082 (Counterclockwise)

Preceding gene: 87200307

Following gene: 87200305

Centisome position: 68.36

GC content: 60.49

Gene sequence:

>486_bases
ATGACCGTTGGACAGCTCATCAAGAGCTTCACCCTGTGGGAGTTCGTGAAGGCGCACTGGCTGACCTTGAAGTATTTCTT
CAAGCCCAAGGCGACGATCAACTACCCGTTCGAAAAGAACCCGCTTTCGCCGCGTTTCCGTGGTGAGCATGCCCTTCGCC
GTTATCCCAATGGCGAGGAACGCTGCATCGCGTGCAAGCTGTGCGAAGCCGTGTGCCCGGCGCAGGCCATCACGATCGAG
GCCGAACCGCGCGAGGACGGCAGCCGCCGCACCACGCGCTACGACATCGACATGACCAAGTGCATCTTCTGCGGCTTTTG
CCAGGAAGCCTGCCCGGTCGACGCGATCGTCGAGGGTCCGAATTTCGAATACGCGACCGAAACGCGCGAGGAGCTGCTTT
ACGACAAGGCAAAGCTCCTTTCGAACGGCGACAAGTGGGAGCGGGCGATTGCCGCGAACCTTGAAGCCGATGCGCCGTAT
CGCTAG

Upstream 100 bases:

>100_bases
ATGACCAGCTGATGCGCCTGGGCTGGAAGGTCTTCCTGCCCGTATCGCTGCTGTTCGTGTTCCTCGTCAGCGGCTACCTC
ATGGCTACCGGACACTTCGC

Downstream 100 bases:

>100_bases
GGGCCCCACGTTCATGGAATACGGCCAATGATCCAGGTATTCGCCTTCTATCTCTTCGCCACGCTGTGCATCTTCAGCGG
CGCGGTGACGATCCTTGCCC

Product: NADH dehydrogenase subunit I

Products: NA

Alternate protein names: NADH dehydrogenase I subunit I; NDH-1 subunit I [H]

Number of amino acids: Translated: 161; Mature: 160

Protein sequence:

>161_residues
MTVGQLIKSFTLWEFVKAHWLTLKYFFKPKATINYPFEKNPLSPRFRGEHALRRYPNGEERCIACKLCEAVCPAQAITIE
AEPREDGSRRTTRYDIDMTKCIFCGFCQEACPVDAIVEGPNFEYATETREELLYDKAKLLSNGDKWERAIAANLEADAPY
R

Sequences:

>Translated_161_residues
MTVGQLIKSFTLWEFVKAHWLTLKYFFKPKATINYPFEKNPLSPRFRGEHALRRYPNGEERCIACKLCEAVCPAQAITIE
AEPREDGSRRTTRYDIDMTKCIFCGFCQEACPVDAIVEGPNFEYATETREELLYDKAKLLSNGDKWERAIAANLEADAPY
R
>Mature_160_residues
TVGQLIKSFTLWEFVKAHWLTLKYFFKPKATINYPFEKNPLSPRFRGEHALRRYPNGEERCIACKLCEAVCPAQAITIEA
EPREDGSRRTTRYDIDMTKCIFCGFCQEACPVDAIVEGPNFEYATETREELLYDKAKLLSNGDKWERAIAANLEADAPYR

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocat

COG id: COG1143

COG function: function code C; Formate hydrogenlyase subunit 6/NADH:ubiquinone oxidoreductase 23 kD subunit (chain I)

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 4Fe-4S ferredoxin-type domains [H]

Homologues:

Organism=Homo sapiens, GI4505371, Length=151, Percent_Identity=80.1324503311258, Blast_Score=256, Evalue=5e-69,
Organism=Escherichia coli, GI1788617, Length=143, Percent_Identity=39.1608391608392, Blast_Score=111, Evalue=2e-26,
Organism=Escherichia coli, GI1789075, Length=127, Percent_Identity=30.7086614173228, Blast_Score=63, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17555194, Length=148, Percent_Identity=75.6756756756757, Blast_Score=240, Evalue=3e-64,
Organism=Drosophila melanogaster, GI17864306, Length=148, Percent_Identity=79.7297297297297, Blast_Score=253, Evalue=4e-68,

Paralogues:

None

Copy number: 60 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001450
- InterPro:   IPR017896
- InterPro:   IPR017900
- InterPro:   IPR012285
- InterPro:   IPR010226 [H]

Pfam domain/function: PF00037 Fer4 [H]

EC number: =1.6.99.5 [H]

Molecular weight: Translated: 18569; Mature: 18438

Theoretical pI: Translated: 6.50; Mature: 6.50

Prosite motif: PS00198 4FE4S_FERREDOXIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

5.0 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
6.2 %Cys+Met (Translated Protein)
5.0 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
5.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTVGQLIKSFTLWEFVKAHWLTLKYFFKPKATINYPFEKNPLSPRFRGEHALRRYPNGEE
CCHHHHHHHHHHHHHHHHHHHHEEEEECCCCEEECCCCCCCCCCCCCCCHHHHCCCCCCH
RCIACKLCEAVCPAQAITIEAEPREDGSRRTTRYDIDMTKCIFCGFCQEACPVDAIVEGP
HHHHHHHHHHHCCCEEEEEECCCCCCCCCCCEEECCCHHHHHHHHHHHHHCCCCEEEECC
NFEYATETREELLYDKAKLLSNGDKWERAIAANLEADAPYR
CCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCCC
>Mature Secondary Structure 
TVGQLIKSFTLWEFVKAHWLTLKYFFKPKATINYPFEKNPLSPRFRGEHALRRYPNGEE
CHHHHHHHHHHHHHHHHHHHHEEEEECCCCEEECCCCCCCCCCCCCCCHHHHCCCCCCH
RCIACKLCEAVCPAQAITIEAEPREDGSRRTTRYDIDMTKCIFCGFCQEACPVDAIVEGP
HHHHHHHHHHHCCCEEEEEECCCCCCCCCCCEEECCCHHHHHHHHHHHHHCCCCEEEECC
NFEYATETREELLYDKAKLLSNGDKWERAIAANLEADAPYR
CCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA