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The map label for this gene is nuoL [H]

Identifier: 87200303

GI number: 87200303

Start: 2431053

End: 2433122

Strand: Reverse

Name: nuoL [H]

Synonym: Saro_2289

Alternate gene names: 87200303

Gene position: 2433122-2431053 (Counterclockwise)

Preceding gene: 87200304

Following gene: 87200302

Centisome position: 68.32

GC content: 63.29

Gene sequence:

>2070_bases
ATGTCTTCCATCCTGATCATCGTATTCCTGCCGCTTCTGGCAGCGATCATCGCCGGGCTCGGCAACAAGAAGCTGGGCGC
CGTTCCGGCCAAGGTCGTGACGACCGGCGCGCTGTTCATCTCGTGCGCGCTGTCGTGGCCGATCTTCCTCTCGTTCCTCG
GCGGTCACGCCGAGGCGAGCGTGACGCCGGTCCTGCACTGGGTCACCTCGGGCGATCTCGATTTCTCGTGGGCCCTGCGC
GTCGACACGCTGACCGCGGTCATGCTGGTGGTCATCACCAGCGTCTCGGCGCTCGTGCACCTCTATTCTTGGGGTTACAT
GAGCGAGGAGCCGGACCAGCCGCGCTTCTTCGCGTATCTCTCGCTCTTCACCTTCGCCATGCTCATGCTGGTGACGGCCG
ACAACCTCGTGCAGATGTTCTTCGGCTGGGAAGGCGTTGGCCTTGCCTCGTACCTGCTGATCGGCTTCTGGTTCCGCAAG
CCCAGCGCCAACGCCGCCGCGATGAAGGCTTTCGTGGTCAACCGCGTGGGCGACCTCGGCTTCATGATGGGCATCTTCGG
GACGTTCCTGGTGTTCGGCACCGTTTCGATCCCTGCTATCCTTGAAGCGGCGCCCGGCATGGCCGGTTCCACCATCGGCT
TCCTCGGTCACCGCTTCGACACGATGACCGTGCTGTGCCTGCTGCTGTTCATCGGCGCGATGGGCAAGTCGGCGCAGCTT
GGCCTGCACACCTGGCTTCCCGACGCGATGGAAGGCCCGACCCCGGTTTCGGCGCTGATCCACGCGGCGACAATGGTCAC
CGCGGGCGTGTTCATGGTTTGCCGTCTCTCGCCGATGTTCGAAGTCAGCCCCACGGCGCTGTCGTTCGTGACCTTCATCG
GCGCGATGACCTGCATTTTCGCCGCGACCGTCGGCACGACGCAGACCGACATCAAGCGCGTGATCGCCTATTCGACCTGT
TCGCAGCTCGGCTACATGTTCTTCGCCGCCGGTGTCTCGGCTTATGGCGCGGCGATGTTCCATCTGTTCACCCACGCCTT
CTTCAAGGCGCTGCTGTTCCTTGGCGCGGGGTCGGTCATCCACGCGATGCACCATGAACAGGACATGCGGTACTACGGCG
GCCTGCGTAAGCAGATCCCGCTGACCTACTGGGCGATGATGATGGGCACGCTGGCGATCACCGGCGTCGGCATCGTCGAC
CTGTTCGGCTTTGCAGGGTTCTACTCGAAGGATGCGATCCTCGAGGCGGCCTATGCCAAGGGTACCGAGCTTGGGCACTT
CGCCTTCTTCATCGGCATCTTCGCTGCCCTGCTGACCAGCTTCTATTCGTGGCGCCTGGTGTTCCTCACCTTCTTCGGCA
AGCCGCGCTGGGAGCAGTCGGAACACATCCAGCATGCGGTCCACGATGCGCATGGGCATGACGATCACGCACACGGCCAC
GCACACGGGCACGCGCACGGCCACGACGACCACGCGCATGGACATCATGACGAGCATGGCGACGGCACGGCGGGCTACCA
TCCGCACGAGAGCCCGCTCAACATGCTGGTTCCGCTCGGCGTCCTTTCGCTCGGCGCGGTCTTTGCCGGCTTCGTGTTCC
ACCACGCGTTCGTCAGCGAAGGCACCGGCCACTTCTGGAAGGGCTCGCTGGTGTTCAGCGAACACCTGATCCACGCGATG
CACGAAGTGCCGACGTGGGTGAAGTGGGCGCCGTTCGCGGTCATGGCCACCGGCCTGCTGATCGCCTGGTATGCCTACAT
CAAGAACACGAAGTTCCCGGCGGCTTTCGTCGAGCAGTTCGCGTTCCTCTACAAGTTCCTGCTCAACAAGTGGTACTTCG
ACGAGCTTTATCACTACATCTTCGTGGTGCCCGCCATGTGGCTTGGCCGGGTGTTCTGGAAGGTGGGTGACCAGGGCATC
ATCGACCGCTTCGGCCCGAACGGTGCCGCATGGGTCGTCGCCCAGGGCAGCCGCGCCGCCGCCAAGCTCCAGTCGGGGTA
TCTCTATAGCTATGCGCTGGTCATGCTCGTCGGACTTGTCGGCGCGATCAGCTGGGTGATCGCACAATGA

Upstream 100 bases:

>100_bases
CGAAGCAGCGATCGGGCTTGCCATTCTGGTCATCTATTTCCGTGGCCGCGGCACGATTGCCGTCGACGACGTCAACCGGA
TGAAAGGCTGAGGCGGGGCA

Downstream 100 bases:

>100_bases
ACGGTTTTCTTGGGACCGGCTTCCCGATCCTTTCGCTGATGCTGCTGGTGCCGCTCGCAGCGGCGGTGGCGTGCCTTGTC
GTCCCGCGCGAACAGGCGCG

Product: NADH dehydrogenase subunit L

Products: NA

Alternate protein names: NADH dehydrogenase I subunit L; NDH-1 subunit L [H]

Number of amino acids: Translated: 689; Mature: 688

Protein sequence:

>689_residues
MSSILIIVFLPLLAAIIAGLGNKKLGAVPAKVVTTGALFISCALSWPIFLSFLGGHAEASVTPVLHWVTSGDLDFSWALR
VDTLTAVMLVVITSVSALVHLYSWGYMSEEPDQPRFFAYLSLFTFAMLMLVTADNLVQMFFGWEGVGLASYLLIGFWFRK
PSANAAAMKAFVVNRVGDLGFMMGIFGTFLVFGTVSIPAILEAAPGMAGSTIGFLGHRFDTMTVLCLLLFIGAMGKSAQL
GLHTWLPDAMEGPTPVSALIHAATMVTAGVFMVCRLSPMFEVSPTALSFVTFIGAMTCIFAATVGTTQTDIKRVIAYSTC
SQLGYMFFAAGVSAYGAAMFHLFTHAFFKALLFLGAGSVIHAMHHEQDMRYYGGLRKQIPLTYWAMMMGTLAITGVGIVD
LFGFAGFYSKDAILEAAYAKGTELGHFAFFIGIFAALLTSFYSWRLVFLTFFGKPRWEQSEHIQHAVHDAHGHDDHAHGH
AHGHAHGHDDHAHGHHDEHGDGTAGYHPHESPLNMLVPLGVLSLGAVFAGFVFHHAFVSEGTGHFWKGSLVFSEHLIHAM
HEVPTWVKWAPFAVMATGLLIAWYAYIKNTKFPAAFVEQFAFLYKFLLNKWYFDELYHYIFVVPAMWLGRVFWKVGDQGI
IDRFGPNGAAWVVAQGSRAAAKLQSGYLYSYALVMLVGLVGAISWVIAQ

Sequences:

>Translated_689_residues
MSSILIIVFLPLLAAIIAGLGNKKLGAVPAKVVTTGALFISCALSWPIFLSFLGGHAEASVTPVLHWVTSGDLDFSWALR
VDTLTAVMLVVITSVSALVHLYSWGYMSEEPDQPRFFAYLSLFTFAMLMLVTADNLVQMFFGWEGVGLASYLLIGFWFRK
PSANAAAMKAFVVNRVGDLGFMMGIFGTFLVFGTVSIPAILEAAPGMAGSTIGFLGHRFDTMTVLCLLLFIGAMGKSAQL
GLHTWLPDAMEGPTPVSALIHAATMVTAGVFMVCRLSPMFEVSPTALSFVTFIGAMTCIFAATVGTTQTDIKRVIAYSTC
SQLGYMFFAAGVSAYGAAMFHLFTHAFFKALLFLGAGSVIHAMHHEQDMRYYGGLRKQIPLTYWAMMMGTLAITGVGIVD
LFGFAGFYSKDAILEAAYAKGTELGHFAFFIGIFAALLTSFYSWRLVFLTFFGKPRWEQSEHIQHAVHDAHGHDDHAHGH
AHGHAHGHDDHAHGHHDEHGDGTAGYHPHESPLNMLVPLGVLSLGAVFAGFVFHHAFVSEGTGHFWKGSLVFSEHLIHAM
HEVPTWVKWAPFAVMATGLLIAWYAYIKNTKFPAAFVEQFAFLYKFLLNKWYFDELYHYIFVVPAMWLGRVFWKVGDQGI
IDRFGPNGAAWVVAQGSRAAAKLQSGYLYSYALVMLVGLVGAISWVIAQ
>Mature_688_residues
SSILIIVFLPLLAAIIAGLGNKKLGAVPAKVVTTGALFISCALSWPIFLSFLGGHAEASVTPVLHWVTSGDLDFSWALRV
DTLTAVMLVVITSVSALVHLYSWGYMSEEPDQPRFFAYLSLFTFAMLMLVTADNLVQMFFGWEGVGLASYLLIGFWFRKP
SANAAAMKAFVVNRVGDLGFMMGIFGTFLVFGTVSIPAILEAAPGMAGSTIGFLGHRFDTMTVLCLLLFIGAMGKSAQLG
LHTWLPDAMEGPTPVSALIHAATMVTAGVFMVCRLSPMFEVSPTALSFVTFIGAMTCIFAATVGTTQTDIKRVIAYSTCS
QLGYMFFAAGVSAYGAAMFHLFTHAFFKALLFLGAGSVIHAMHHEQDMRYYGGLRKQIPLTYWAMMMGTLAITGVGIVDL
FGFAGFYSKDAILEAAYAKGTELGHFAFFIGIFAALLTSFYSWRLVFLTFFGKPRWEQSEHIQHAVHDAHGHDDHAHGHA
HGHAHGHDDHAHGHHDEHGDGTAGYHPHESPLNMLVPLGVLSLGAVFAGFVFHHAFVSEGTGHFWKGSLVFSEHLIHAMH
EVPTWVKWAPFAVMATGLLIAWYAYIKNTKFPAAFVEQFAFLYKFLLNKWYFDELYHYIFVVPAMWLGRVFWKVGDQGII
DRFGPNGAAWVVAQGSRAAAKLQSGYLYSYALVMLVGLVGAISWVIAQ

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocat

COG id: COG1009

COG function: function code CP; NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter, MnhA subunit

Gene ontology:

Cell location: Cellular chromatophore membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the complex I subunit 5 family [H]

Homologues:

Organism=Homo sapiens, GI251831117, Length=403, Percent_Identity=40.9429280397022, Blast_Score=299, Evalue=6e-81,
Organism=Escherichia coli, GI1788614, Length=460, Percent_Identity=44.1304347826087, Blast_Score=353, Evalue=2e-98,
Organism=Escherichia coli, GI1788829, Length=433, Percent_Identity=30.4849884526559, Blast_Score=146, Evalue=6e-36,
Organism=Escherichia coli, GI1788827, Length=418, Percent_Identity=28.4688995215311, Blast_Score=115, Evalue=1e-26,
Organism=Escherichia coli, GI1788831, Length=343, Percent_Identity=28.2798833819242, Blast_Score=105, Evalue=8e-24,
Organism=Escherichia coli, GI1788613, Length=467, Percent_Identity=23.7687366167024, Blast_Score=75, Evalue=1e-14,
Organism=Escherichia coli, GI145693160, Length=267, Percent_Identity=24.7191011235955, Blast_Score=68, Evalue=2e-12,
Organism=Escherichia coli, GI2367154, Length=196, Percent_Identity=27.0408163265306, Blast_Score=65, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001750
- InterPro:   IPR001516
- InterPro:   IPR003945
- InterPro:   IPR018393 [H]

Pfam domain/function: PF00361 Oxidored_q1; PF00662 Oxidored_q1_N [H]

EC number: =1.6.99.5 [H]

Molecular weight: Translated: 75377; Mature: 75246

Theoretical pI: Translated: 7.13; Mature: 7.13

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHCCHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SSILIIVFLPLLAAIIAGLGNKKLGAVPAKVVTTGALFISCALSWPIFLSFLGGHAEAS
CCHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC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HHHHCCHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8566820 [H]