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The map label for this gene is phoR [H]

Identifier: 87200289

GI number: 87200289

Start: 2415703

End: 2416887

Strand: Direct

Name: phoR [H]

Synonym: Saro_2275

Alternate gene names: 87200289

Gene position: 2415703-2416887 (Clockwise)

Preceding gene: 87200288

Following gene: 87200290

Centisome position: 67.83

GC content: 67.26

Gene sequence:

>1185_bases
ATGAAGGGTTTGTCGCTGCCTCTCCCCAGCATGTTCGTCGCCCTGTGCGCGGCCGTGGTCATGTACTTCGGCGGCGCCGG
CTTCTGGCTCTCGCTCGCGATCCTGCTCGTCTGGCTGGCGACACTGTGGCTCGCCCGACCCGAGCCGACGGTGGAAACCC
GCAGCAGGGATGACGGCAGCGTCTCGCGCCAGGCAATGATCGAACTGGTCGAACCCTTCGGCCTGCCGGTCCTGATGCTG
GACGGACAGCGCATCGCAGCCGCCAACGCGGCCGCGCGGGAGGAACTCGGCAGCCATATCGTCGGCCAGGACGCGCGCGT
GGCGCTGCGCCATCCCGAAGCGGTCCGCCTCCTGGACAAGCCCGAGGGCCGGGCGCTGGTGCGGGGTCTCACGGGCGCGC
GCAGCATCTGGCAGGTAAGCCGCGTGCCGATCGACGAACGCTTCTCGCTGATCGAGTTCGTCAACCGCACGGCAGAGGCC
GATATCAGCCGCGCGCATACCGACTTCGTGGCCAACGCCAGCCACGAACTGCGCACCCCGCTCGCCTCGATCATCGGCTA
TATCGAGACGCTGGCCGATCCCGACGCCAAAGTCGACGAAGCAACCGCGGCGCGCTTCCATGCCACGGTGCTGCGCGAGG
CACGGCGTCTGCAAAGCCTGGTCGAAGATCTCATGTCGCTTTCCCGGATCGAGGCCGAGAAGCACGAGTTGCCGCGCGAT
CGCATCGATCTCGGCCAGCTTGTCGGCAGCATCGCCAGCGAAACAGCGATGACCGTGGGCGACGGGCGCCTCGAAGTCGA
GACGTGCCCCGCGCTCGTGGCGGGCGACCGGCAGCAGCTTGACCAACTCGTGCGCAATCTGATCGACAACGCGTTCAAGT
ATGGAGACACTGCCGCCCCTGTCGCGGTCAAGGTGGCGATTCACGGCAACGAAGCGGAGCTGTCGGTGACCGACAGGGGC
GAAGGCATCCACCCCGACCACCTGCCCTATCTCACCCGGCGCTTCTATCGGACCGACCCGGGACGCAGCCGCGCGGCGGG
CGGGACGGGCCTCGGGCTCGCCATCGTGAAGCACATCGTGGAGCGGCATCGCGGCAAGCTGGACATCGCCAGCCAGCTTG
GAATCGGCACGACGGTTACCGTCAGATTGCCGATTGCAAACCTGCCCGCTGTTGCTGCAGCCTGA

Upstream 100 bases:

>100_bases
CGCTTGCGCCCGTGGTTTCGCCTGGCCTATCTGCGTGCGCAGCAAGCCGACCATCCGGACGGCGATTCGCGAGCGCAGGC
AATCCACACGGCGTGATTCG

Downstream 100 bases:

>100_bases
CTGCTGTCATAAAGCTGTCATGCAACCGTCGCATTGGCCCCCTGCCCACAGGGATGAAGGCTGAAACCATGTCGATGATT
CGCAATATTGCGCTTGCCGC

Product: histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 394; Mature: 394

Protein sequence:

>394_residues
MKGLSLPLPSMFVALCAAVVMYFGGAGFWLSLAILLVWLATLWLARPEPTVETRSRDDGSVSRQAMIELVEPFGLPVLML
DGQRIAAANAAAREELGSHIVGQDARVALRHPEAVRLLDKPEGRALVRGLTGARSIWQVSRVPIDERFSLIEFVNRTAEA
DISRAHTDFVANASHELRTPLASIIGYIETLADPDAKVDEATAARFHATVLREARRLQSLVEDLMSLSRIEAEKHELPRD
RIDLGQLVGSIASETAMTVGDGRLEVETCPALVAGDRQQLDQLVRNLIDNAFKYGDTAAPVAVKVAIHGNEAELSVTDRG
EGIHPDHLPYLTRRFYRTDPGRSRAAGGTGLGLAIVKHIVERHRGKLDIASQLGIGTTVTVRLPIANLPAVAAA

Sequences:

>Translated_394_residues
MKGLSLPLPSMFVALCAAVVMYFGGAGFWLSLAILLVWLATLWLARPEPTVETRSRDDGSVSRQAMIELVEPFGLPVLML
DGQRIAAANAAAREELGSHIVGQDARVALRHPEAVRLLDKPEGRALVRGLTGARSIWQVSRVPIDERFSLIEFVNRTAEA
DISRAHTDFVANASHELRTPLASIIGYIETLADPDAKVDEATAARFHATVLREARRLQSLVEDLMSLSRIEAEKHELPRD
RIDLGQLVGSIASETAMTVGDGRLEVETCPALVAGDRQQLDQLVRNLIDNAFKYGDTAAPVAVKVAIHGNEAELSVTDRG
EGIHPDHLPYLTRRFYRTDPGRSRAAGGTGLGLAIVKHIVERHRGKLDIASQLGIGTTVTVRLPIANLPAVAAA
>Mature_394_residues
MKGLSLPLPSMFVALCAAVVMYFGGAGFWLSLAILLVWLATLWLARPEPTVETRSRDDGSVSRQAMIELVEPFGLPVLML
DGQRIAAANAAAREELGSHIVGQDARVALRHPEAVRLLDKPEGRALVRGLTGARSIWQVSRVPIDERFSLIEFVNRTAEA
DISRAHTDFVANASHELRTPLASIIGYIETLADPDAKVDEATAARFHATVLREARRLQSLVEDLMSLSRIEAEKHELPRD
RIDLGQLVGSIASETAMTVGDGRLEVETCPALVAGDRQQLDQLVRNLIDNAFKYGDTAAPVAVKVAIHGNEAELSVTDRG
EGIHPDHLPYLTRRFYRTDPGRSRAAGGTGLGLAIVKHIVERHRGKLDIASQLGIGTTVTVRLPIANLPAVAAA

Specific function: Member of the two-component regulatory system phoP/phoR involved in the alkaline phosphatase genes regulation. PhoR may function as a membrane-associated protein kinase that phosphorylates phoP in response to environmental signals [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1786600, Length=307, Percent_Identity=33.2247557003257, Blast_Score=146, Evalue=2e-36,
Organism=Escherichia coli, GI1788393, Length=222, Percent_Identity=36.036036036036, Blast_Score=118, Evalue=7e-28,
Organism=Escherichia coli, GI1786783, Length=249, Percent_Identity=29.718875502008, Blast_Score=100, Evalue=1e-22,
Organism=Escherichia coli, GI145693157, Length=253, Percent_Identity=29.6442687747036, Blast_Score=100, Evalue=1e-22,
Organism=Escherichia coli, GI1788713, Length=247, Percent_Identity=29.1497975708502, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI48994928, Length=320, Percent_Identity=26.5625, Blast_Score=91, Evalue=9e-20,
Organism=Escherichia coli, GI1790346, Length=221, Percent_Identity=29.4117647058824, Blast_Score=89, Evalue=5e-19,
Organism=Escherichia coli, GI1787894, Length=228, Percent_Identity=30.2631578947368, Blast_Score=87, Evalue=1e-18,
Organism=Escherichia coli, GI1790436, Length=222, Percent_Identity=30.6306306306306, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI1789149, Length=233, Percent_Identity=30.9012875536481, Blast_Score=86, Evalue=3e-18,
Organism=Escherichia coli, GI1789808, Length=226, Percent_Identity=27.4336283185841, Blast_Score=81, Evalue=1e-16,
Organism=Escherichia coli, GI1786912, Length=226, Percent_Identity=27.8761061946903, Blast_Score=78, Evalue=1e-15,
Organism=Escherichia coli, GI1790861, Length=220, Percent_Identity=27.7272727272727, Blast_Score=78, Evalue=1e-15,
Organism=Escherichia coli, GI87082128, Length=259, Percent_Identity=25.8687258687259, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1788549, Length=237, Percent_Identity=26.1603375527426, Blast_Score=75, Evalue=7e-15,
Organism=Escherichia coli, GI87081816, Length=258, Percent_Identity=26.7441860465116, Blast_Score=75, Evalue=9e-15,
Organism=Escherichia coli, GI1790300, Length=285, Percent_Identity=27.3684210526316, Blast_Score=70, Evalue=3e-13,
Organism=Escherichia coli, GI1790551, Length=224, Percent_Identity=30.3571428571429, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1789403, Length=201, Percent_Identity=32.3383084577114, Blast_Score=67, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR000014
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 42701; Mature: 42701

Theoretical pI: Translated: 6.59; Mature: 6.59

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKGLSLPLPSMFVALCAAVVMYFGGAGFWLSLAILLVWLATLWLARPEPTVETRSRDDGS
CCCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCH
VSRQAMIELVEPFGLPVLMLDGQRIAAANAAAREELGSHIVGQDARVALRHPEAVRLLDK
HHHHHHHHHHHHCCCCEEEECCCCHHHHHHHHHHHHHHHHCCCCCCEEECCCHHHHHCCC
PEGRALVRGLTGARSIWQVSRVPIDERFSLIEFVNRTAEADISRAHTDFVANASHELRTP
CCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHH
LASIIGYIETLADPDAKVDEATAARFHATVLREARRLQSLVEDLMSLSRIEAEKHELPRD
HHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHH
RIDLGQLVGSIASETAMTVGDGRLEVETCPALVAGDRQQLDQLVRNLIDNAFKYGDTAAP
HHHHHHHHHHHHHHHHEEECCCEEEEECCCHHHCCCHHHHHHHHHHHHHHHHHCCCCCCC
VAVKVAIHGNEAELSVTDRGEGIHPDHLPYLTRRFYRTDPGRSRAAGGTGLGLAIVKHIV
EEEEEEEECCCEEEEEECCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHH
ERHRGKLDIASQLGIGTTVTVRLPIANLPAVAAA
HHHCCCEEHHHHCCCCEEEEEEEECCCCCHHHCC
>Mature Secondary Structure
MKGLSLPLPSMFVALCAAVVMYFGGAGFWLSLAILLVWLATLWLARPEPTVETRSRDDGS
CCCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCH
VSRQAMIELVEPFGLPVLMLDGQRIAAANAAAREELGSHIVGQDARVALRHPEAVRLLDK
HHHHHHHHHHHHCCCCEEEECCCCHHHHHHHHHHHHHHHHCCCCCCEEECCCHHHHHCCC
PEGRALVRGLTGARSIWQVSRVPIDERFSLIEFVNRTAEADISRAHTDFVANASHELRTP
CCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHH
LASIIGYIETLADPDAKVDEATAARFHATVLREARRLQSLVEDLMSLSRIEAEKHELPRD
HHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHH
RIDLGQLVGSIASETAMTVGDGRLEVETCPALVAGDRQQLDQLVRNLIDNAFKYGDTAAP
HHHHHHHHHHHHHHHHEEECCCEEEEECCCHHHCCCHHHHHHHHHHHHHHHHHCCCCCCC
VAVKVAIHGNEAELSVTDRGEGIHPDHLPYLTRRFYRTDPGRSRAAGGTGLGLAIVKHIV
EEEEEEEECCCEEEEEECCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHH
ERHRGKLDIASQLGIGTTVTVRLPIANLPAVAAA
HHHCCCEEHHHHCCCCEEEEEEEECCCCCHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 3142862; 9387221; 9384377 [H]