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The map label for this gene is nrdR

Identifier: 87200256

GI number: 87200256

Start: 2384388

End: 2384867

Strand: Direct

Name: nrdR

Synonym: Saro_2242

Alternate gene names: 87200256

Gene position: 2384388-2384867 (Clockwise)

Preceding gene: 87200255

Following gene: 87200257

Centisome position: 66.95

GC content: 62.92

Gene sequence:

>480_bases
ATGCGTTGCCCATTCTGCGCCCATGACAACAGCCAGGTAAAGGACAGCCGGCCGAGCGAGGACAACACCTCGATCCGCCG
GCGCCGCCAGTGCGAGGGTTGCGGGGCACGCTTCACCACCTTCGAGCGCGTCCAACTGCGCGAAGTCGTGGTGGTGAAGA
GCGGTGAGCGCCGGGAACCGTTCGACCGCTCCAAGATCGAGCAGTCGGTCGCGCTTGCCTGTCGCAAGCGTCCGGTCAAC
CAGGAGCGGCTGGACCAGCTCGTTTCCGGCATCCAGCGCCAGATCGAAACGATGGGCGACGCGGAAGTGGCGTCGAAGGT
CATCGGCGAAATGGTGATGGAAGGTCTGCGCCAGCTCGATAGCGTGGCCTATATCCGCTTCGCCAGCGTCTATCGCGACT
TCACAGAAGCACGCGACTTTGAGGAGTTCGCCAGCAGCGTGCAGGAAATGAGCGTGCACGAGGTTTCAGGCGGTGAATGA

Upstream 100 bases:

>100_bases
GGCGCTGTGGCCGGTGCGGTTCTCCCGGTCGTTTCGATCCCGCTCGGCATCGTCGCCGGGGCGGGGTTCATGTTCTGGAA
GCGGATCAGCCGATAACCTG

Downstream 100 bases:

>100_bases
GGCAGAAGGCGCCGCGCGCCACCCGGTAATCGTCCTGGTTCGGCCGCAGCTTGGCGAAAACATCGGCAAGGCCGCGCGCG
CAATGCTCAACTTCGGCCTT

Product: transcriptional regulator NrdR

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 159; Mature: 159

Protein sequence:

>159_residues
MRCPFCAHDNSQVKDSRPSEDNTSIRRRRQCEGCGARFTTFERVQLREVVVVKSGERREPFDRSKIEQSVALACRKRPVN
QERLDQLVSGIQRQIETMGDAEVASKVIGEMVMEGLRQLDSVAYIRFASVYRDFTEARDFEEFASSVQEMSVHEVSGGE

Sequences:

>Translated_159_residues
MRCPFCAHDNSQVKDSRPSEDNTSIRRRRQCEGCGARFTTFERVQLREVVVVKSGERREPFDRSKIEQSVALACRKRPVN
QERLDQLVSGIQRQIETMGDAEVASKVIGEMVMEGLRQLDSVAYIRFASVYRDFTEARDFEEFASSVQEMSVHEVSGGE
>Mature_159_residues
MRCPFCAHDNSQVKDSRPSEDNTSIRRRRQCEGCGARFTTFERVQLREVVVVKSGERREPFDRSKIEQSVALACRKRPVN
QERLDQLVSGIQRQIETMGDAEVASKVIGEMVMEGLRQLDSVAYIRFASVYRDFTEARDFEEFASSVQEMSVHEVSGGE

Specific function: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes

COG id: COG1327

COG function: function code K; Predicted transcriptional regulator, consists of a Zn-ribbon and ATP-cone domains

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ATP-cone domain

Homologues:

Organism=Escherichia coli, GI1786615, Length=142, Percent_Identity=47.1830985915493, Blast_Score=132, Evalue=8e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NRDR_NOVAD (Q2G644)

Other databases:

- EMBL:   CP000248
- RefSeq:   YP_497513.1
- STRING:   Q2G644
- GeneID:   3916558
- GenomeReviews:   CP000248_GR
- KEGG:   nar:Saro_2242
- eggNOG:   COG1327
- HOGENOM:   HBG351755
- OMA:   FASVYRD
- PhylomeDB:   Q2G644
- ProtClustDB:   PRK00464
- BioCyc:   NARO279238:SARO_2242-MONOMER
- GO:   GO:0006350
- HAMAP:   MF_00440
- InterPro:   IPR005144
- InterPro:   IPR003796
- TIGRFAMs:   TIGR00244

Pfam domain/function: PF03477 ATP-cone

EC number: NA

Molecular weight: Translated: 18184; Mature: 18184

Theoretical pI: Translated: 5.88; Mature: 5.88

Prosite motif: PS51161 ATP_CONE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.1 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
6.3 %Cys+Met (Translated Protein)
3.1 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
6.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRCPFCAHDNSQVKDSRPSEDNTSIRRRRQCEGCGARFTTFERVQLREVVVVKSGERREP
CCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCCCCC
FDRSKIEQSVALACRKRPVNQERLDQLVSGIQRQIETMGDAEVASKVIGEMVMEGLRQLD
CCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHH
SVAYIRFASVYRDFTEARDFEEFASSVQEMSVHEVSGGE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MRCPFCAHDNSQVKDSRPSEDNTSIRRRRQCEGCGARFTTFERVQLREVVVVKSGERREP
CCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCCCCC
FDRSKIEQSVALACRKRPVNQERLDQLVSGIQRQIETMGDAEVASKVIGEMVMEGLRQLD
CCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHH
SVAYIRFASVYRDFTEARDFEEFASSVQEMSVHEVSGGE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA