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The map label for this gene is hmrR2 [H]

Identifier: 87200160

GI number: 87200160

Start: 2282709

End: 2283098

Strand: Direct

Name: hmrR2 [H]

Synonym: Saro_2144

Alternate gene names: 87200160

Gene position: 2282709-2283098 (Clockwise)

Preceding gene: 87200159

Following gene: 87200165

Centisome position: 64.09

GC content: 61.28

Gene sequence:

>390_bases
ATGAACATCGGACAGGCATCGAAGACCACTGGCGTGTCGGAGCGGATGATCCGGCACTATGAGCGCGTAGGTCTGATGCC
GCCCCCTGACCGACGCGACAATGGCTACAGGGACTATTCACCGCAATCGATCGAGCGCCTGCGCTTCATTGCTAACGCCC
GCGGCCTTGGCTTCTCGCTTGAGGAAATCACCACTCTCCTCGGCCTATGGGACAACCGCGAGCGGACGAGCAGTGAAGTG
AAGGCCGTTGCCCTGGCACATGCCGATGACCTTGGCCGCAAAGCGGCAGCACTTGAAGCCATGCGTCGCGCCTTGCTGGA
ACTGGCCGAAGGGTGCAGCGGCGACAGCAGACCCGATTGTCCGATCCTCGATGGGATCGCAGTGAGTTGA

Upstream 100 bases:

>100_bases
GGCTGATCCCTTACGCATTCCTGTTCACCTGTCCGCTGCTGCACTTCTTCCATGGCGGCCACCACCAAGGACGCCACCCC
AAGTTCGGCGAACAGCAGCC

Downstream 100 bases:

>100_bases
CCAGATCCTCTGGACACCTGCACATCGATGCGGTCGCTCGCGAACACATCCGGACGGAAAGATTGCTCTTAATCAGCGGG
TCCTAGGTTCGAGCCCTAGT

Product: MerR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 129; Mature: 129

Protein sequence:

>129_residues
MNIGQASKTTGVSERMIRHYERVGLMPPPDRRDNGYRDYSPQSIERLRFIANARGLGFSLEEITTLLGLWDNRERTSSEV
KAVALAHADDLGRKAAALEAMRRALLELAEGCSGDSRPDCPILDGIAVS

Sequences:

>Translated_129_residues
MNIGQASKTTGVSERMIRHYERVGLMPPPDRRDNGYRDYSPQSIERLRFIANARGLGFSLEEITTLLGLWDNRERTSSEV
KAVALAHADDLGRKAAALEAMRRALLELAEGCSGDSRPDCPILDGIAVS
>Mature_129_residues
MNIGQASKTTGVSERMIRHYERVGLMPPPDRRDNGYRDYSPQSIERLRFIANARGLGFSLEEITTLLGLWDNRERTSSEV
KAVALAHADDLGRKAAALEAMRRALLELAEGCSGDSRPDCPILDGIAVS

Specific function: Transcriptional regulator involved in acid tolerance. Binds copper [H]

COG id: COG0789

COG function: function code K; Predicted transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH merR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1786695, Length=127, Percent_Identity=40.1574803149606, Blast_Score=107, Evalue=3e-25,
Organism=Escherichia coli, GI1789687, Length=127, Percent_Identity=33.8582677165354, Blast_Score=77, Evalue=3e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011789
- InterPro:   IPR009061
- InterPro:   IPR000551
- InterPro:   IPR015358 [H]

Pfam domain/function: PF00376 MerR; PF09278 MerR-DNA-bind [H]

EC number: NA

Molecular weight: Translated: 14214; Mature: 14214

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: PS00552 HTH_MERR_1 ; PS50937 HTH_MERR_2 ; PS00216 SUGAR_TRANSPORT_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNIGQASKTTGVSERMIRHYERVGLMPPPDRRDNGYRDYSPQSIERLRFIANARGLGFSL
CCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCH
EEITTLLGLWDNRERTSSEVKAVALAHADDLGRKAAALEAMRRALLELAEGCSGDSRPDC
HHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
PILDGIAVS
CCCCCCCCC
>Mature Secondary Structure
MNIGQASKTTGVSERMIRHYERVGLMPPPDRRDNGYRDYSPQSIERLRFIANARGLGFSL
CCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCH
EEITTLLGLWDNRERTSSEVKAVALAHADDLGRKAAALEAMRRALLELAEGCSGDSRPDC
HHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
PILDGIAVS
CCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11481431 [H]