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The map label for this gene is mrdB [H]

Identifier: 87200148

GI number: 87200148

Start: 2271243

End: 2272358

Strand: Direct

Name: mrdB [H]

Synonym: Saro_2132

Alternate gene names: 87200148

Gene position: 2271243-2272358 (Clockwise)

Preceding gene: 87200147

Following gene: 87200156

Centisome position: 63.77

GC content: 65.23

Gene sequence:

>1116_bases
ATGCCGCGCGCCTATGTCCCCGCCGCGATCGCGCGCCAGCCGTGGAGCGTGCTGCTGCCGCTGACGGCGCTGGTCAGCTT
CGGCGCGGCGGTGCTGGATTCGGCGGCGGGAGGGCGGTTCACCACCTGGTCGCTGTCGCACCTCGTGCGCTTCGTCATCT
TCCTGGTGATGGCGGCGGTCATCGCGCGGCTGCCGCAGGACCTGTTCAAGCGCATGGCGATCCCGGTCTATGCCACACTG
TGCCTGCTGCTGGTGCTGGTGGAGCTGATCGGCGGCATCGGCGGTGGCAGCCAGCGCTGGCTCAATCTCGGGTTCATGAC
GCTGCAACCCTCGGAACTGATGAAGCCGGGCATCGTGCTGGTGCTGGCGTGGTTCTATTCGATCCTGCCCATCGGCGAGA
CACAAAGCTGGCGCGCGCTTGTGCCGGCGGGGATTCTGCTGGGCATTCCGGCGGGGCTGGTCATGCTCCAGCCGGATCTG
GGCACCGGCCTTGCCATCTCGTTCGGCGCGGTCGTTGTCATGTTCCTGGCGGGATTGCCGCTGCGCTGGTTCCTGGGCGC
GGGCGCAGCGGGCCTTATCATTGCGCCGCTCGCGTTCTTCACGCTTCTGCACGACTACCAGCGCAAGCGCGTGCTGGTGT
TCCTCGATCCCGAGAACGATCCGCTGGGCTCTGGCTACCACATCACGCAGTCGAAGATCGCGATCGGTTCGGGCGGGTTC
TTCGGCAAGGGATTCGGCAACGGGTCGCAGAGCCACCTCAACTACCTGCCCGAAGCCCACACCGACTTCGTCTTCGCGAC
GATGGCAGAGGAATGGGGCATGCTGGGCGGCCTGTTCGTGCTGATCGTGTTCGGCCTGATCTTCCGCTGGGGACTGAAGG
TAGCGACGAACGCGCCGGATCGCTTCTCGCGCCTGCTGGCCGCGGGCATGACGATGACGATCTTCTTCTACATGTGCATC
AACCTGATGATGGTCATGGGCCTTGCCCCGGTGGTCGGCATTCCGCTTCCGTGGATGAGCCACGGCGGTTCCTCGATGAT
GACGAACATGATCTGCATCGGCACGATCATGGCCGTAGAACGGTGGAGCCGGTCGGGTCCGCGAAGCCTGTCCTGA

Upstream 100 bases:

>100_bases
TCCAGACCGACGCCGCAGCGCCCGCTCCGGAACCGGAAGCGCCGCCGCAGGTGCAGGTGCCCACTCCGGCGCCGTCGCCC
ACTCCAGCGGGAGGGCAATG

Downstream 100 bases:

>100_bases
AAAACGCAAAATTGGGGCTTGGCAGGGCGTATAAAATCGCTATTGGGGCGGCTCCCGAACGGGAATGCCTGATGGCATGG
ACGCATAGCTCAGTTGGTAG

Product: rod shape-determining protein RodA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 371; Mature: 370

Protein sequence:

>371_residues
MPRAYVPAAIARQPWSVLLPLTALVSFGAAVLDSAAGGRFTTWSLSHLVRFVIFLVMAAVIARLPQDLFKRMAIPVYATL
CLLLVLVELIGGIGGGSQRWLNLGFMTLQPSELMKPGIVLVLAWFYSILPIGETQSWRALVPAGILLGIPAGLVMLQPDL
GTGLAISFGAVVVMFLAGLPLRWFLGAGAAGLIIAPLAFFTLLHDYQRKRVLVFLDPENDPLGSGYHITQSKIAIGSGGF
FGKGFGNGSQSHLNYLPEAHTDFVFATMAEEWGMLGGLFVLIVFGLIFRWGLKVATNAPDRFSRLLAAGMTMTIFFYMCI
NLMMVMGLAPVVGIPLPWMSHGGSSMMTNMICIGTIMAVERWSRSGPRSLS

Sequences:

>Translated_371_residues
MPRAYVPAAIARQPWSVLLPLTALVSFGAAVLDSAAGGRFTTWSLSHLVRFVIFLVMAAVIARLPQDLFKRMAIPVYATL
CLLLVLVELIGGIGGGSQRWLNLGFMTLQPSELMKPGIVLVLAWFYSILPIGETQSWRALVPAGILLGIPAGLVMLQPDL
GTGLAISFGAVVVMFLAGLPLRWFLGAGAAGLIIAPLAFFTLLHDYQRKRVLVFLDPENDPLGSGYHITQSKIAIGSGGF
FGKGFGNGSQSHLNYLPEAHTDFVFATMAEEWGMLGGLFVLIVFGLIFRWGLKVATNAPDRFSRLLAAGMTMTIFFYMCI
NLMMVMGLAPVVGIPLPWMSHGGSSMMTNMICIGTIMAVERWSRSGPRSLS
>Mature_370_residues
PRAYVPAAIARQPWSVLLPLTALVSFGAAVLDSAAGGRFTTWSLSHLVRFVIFLVMAAVIARLPQDLFKRMAIPVYATLC
LLLVLVELIGGIGGGSQRWLNLGFMTLQPSELMKPGIVLVLAWFYSILPIGETQSWRALVPAGILLGIPAGLVMLQPDLG
TGLAISFGAVVVMFLAGLPLRWFLGAGAAGLIIAPLAFFTLLHDYQRKRVLVFLDPENDPLGSGYHITQSKIAIGSGGFF
GKGFGNGSQSHLNYLPEAHTDFVFATMAEEWGMLGGLFVLIVFGLIFRWGLKVATNAPDRFSRLLAAGMTMTIFFYMCIN
LMMVMGLAPVVGIPLPWMSHGGSSMMTNMICIGTIMAVERWSRSGPRSLS

Specific function: This is one of the proteins responsible for the rod shape of the cell. It is required for the expression of the enzymatic activity of PBP2, which is thought to synthesize peptidoglycan in the step of initiation of cell elongation [H]

COG id: COG0772

COG function: function code D; Bacterial cell division membrane protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ftsW/rodA/spoVE family [H]

Homologues:

Organism=Escherichia coli, GI1786853, Length=321, Percent_Identity=42.3676012461059, Blast_Score=227, Evalue=1e-60,
Organism=Escherichia coli, GI1786277, Length=353, Percent_Identity=32.5779036827195, Blast_Score=152, Evalue=4e-38,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001182
- InterPro:   IPR018365
- InterPro:   IPR011923 [H]

Pfam domain/function: PF01098 FTSW_RODA_SPOVE [H]

EC number: NA

Molecular weight: Translated: 40069; Mature: 39937

Theoretical pI: Translated: 9.85; Mature: 9.85

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
5.4 %Met     (Translated Protein)
6.2 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
5.1 %Met     (Mature Protein)
5.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPRAYVPAAIARQPWSVLLPLTALVSFGAAVLDSAAGGRFTTWSLSHLVRFVIFLVMAAV
CCCCCCCHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCEEHHHHHHHHHHHHHHHHHHH
IARLPQDLFKRMAIPVYATLCLLLVLVELIGGIGGGSQRWLNLGFMTLQPSELMKPGIVL
HHHCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHEEECEEEECHHHHHCCHHHH
VLAWFYSILPIGETQSWRALVPAGILLGIPAGLVMLQPDLGTGLAISFGAVVVMFLAGLP
HHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCCEEEECCCCCCCHHHHHHHHHHHHHCCCC
LRWFLGAGAAGLIIAPLAFFTLLHDYQRKRVLVFLDPENDPLGSGYHITQSKIAIGSGGF
HHHHHCCCCHHHHHHHHHHHHHHHHHHHCEEEEEECCCCCCCCCCEEEECCEEEECCCCC
FGKGFGNGSQSHLNYLPEAHTDFVFATMAEEWGMLGGLFVLIVFGLIFRWGLKVATNAPD
CCCCCCCCCHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHCCCCHH
RFSRLLAAGMTMTIFFYMCINLMMVMGLAPVVGIPLPWMSHGGSSMMTNMICIGTIMAVE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHCCCCHHHHHHHHHHHHHHHHH
RWSRSGPRSLS
HHCCCCCCCCC
>Mature Secondary Structure 
PRAYVPAAIARQPWSVLLPLTALVSFGAAVLDSAAGGRFTTWSLSHLVRFVIFLVMAAV
CCCCCCHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCEEHHHHHHHHHHHHHHHHHHH
IARLPQDLFKRMAIPVYATLCLLLVLVELIGGIGGGSQRWLNLGFMTLQPSELMKPGIVL
HHHCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHEEECEEEECHHHHHCCHHHH
VLAWFYSILPIGETQSWRALVPAGILLGIPAGLVMLQPDLGTGLAISFGAVVVMFLAGLP
HHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCCEEEECCCCCCCHHHHHHHHHHHHHCCCC
LRWFLGAGAAGLIIAPLAFFTLLHDYQRKRVLVFLDPENDPLGSGYHITQSKIAIGSGGF
HHHHHCCCCHHHHHHHHHHHHHHHHHHHCEEEEEECCCCCCCCCCEEEECCEEEECCCCC
FGKGFGNGSQSHLNYLPEAHTDFVFATMAEEWGMLGGLFVLIVFGLIFRWGLKVATNAPD
CCCCCCCCCHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHCCCCHH
RFSRLLAAGMTMTIFFYMCINLMMVMGLAPVVGIPLPWMSHGGSSMMTNMICIGTIMAVE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHCCCCHHHHHHHHHHHHHHHHH
RWSRSGPRSLS
HHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]