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The map label for this gene is grxC [H]

Identifier: 87200029

GI number: 87200029

Start: 2145858

End: 2146124

Strand: Reverse

Name: grxC [H]

Synonym: Saro_2013

Alternate gene names: 87200029

Gene position: 2146124-2145858 (Counterclockwise)

Preceding gene: 87200032

Following gene: 87200028

Centisome position: 60.26

GC content: 62.17

Gene sequence:

>267_bases
ATGCCCAATATGCCCAAGGTTGAAATGTACACCAAGTGGGGCTGCCCCTACTGCTTTCGCGCCAAGCAACTGCTGGACGG
CAAGGGCGTATCCTACGAGGAAATCGACGTGACGATGGGCGGGCCGAAGAAGACCGAGATGCTCGAGCGCGCGCCAGGGC
ACACCACCGTTCCCTCGATCTTCATCGACGGCCTCCACGTGGGCGGTTCCGATGACCTCGCCGCGCTCAACGCGCAGGGC
AAGCTGGACATGATGCTGGGCCTGTGA

Upstream 100 bases:

>100_bases
GCCCCGGCGGTTGATGGCCATGCCCGACTTGCGGCGCATGACACGCCAACCCATGTGTGTTAGCGATTTTCCCATTTCAA
GACCCCAGTTCGAGGTACCG

Downstream 100 bases:

>100_bases
GCAGCGGCGCACCGCGGGGACCTGCCAAGGTCGCGCTGTTCCAGATGACCAGCGGCATCGATCCGCTGGTCAATGCCGCC
GCCATCGTGGATGCCGCGAC

Product: glutaredoxin GrxC

Products: NA

Alternate protein names: Grx3 [H]

Number of amino acids: Translated: 88; Mature: 87

Protein sequence:

>88_residues
MPNMPKVEMYTKWGCPYCFRAKQLLDGKGVSYEEIDVTMGGPKKTEMLERAPGHTTVPSIFIDGLHVGGSDDLAALNAQG
KLDMMLGL

Sequences:

>Translated_88_residues
MPNMPKVEMYTKWGCPYCFRAKQLLDGKGVSYEEIDVTMGGPKKTEMLERAPGHTTVPSIFIDGLHVGGSDDLAALNAQG
KLDMMLGL
>Mature_87_residues
PNMPKVEMYTKWGCPYCFRAKQLLDGKGVSYEEIDVTMGGPKKTEMLERAPGHTTVPSIFIDGLHVGGSDDLAALNAQGK
LDMMLGL

Specific function: The disulfide bond functions as an electron carrier in the glutathione-dependent synthesis of deoxyribonucleotides by the enzyme ribonucleotide reductase. In addition, it is also involved in reducing some disulfides in a coupled system with glutathione re

COG id: COG0695

COG function: function code O; Glutaredoxin and related proteins

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 glutaredoxin domain [H]

Homologues:

Organism=Escherichia coli, GI1790039, Length=83, Percent_Identity=55.421686746988, Blast_Score=96, Evalue=4e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011767
- InterPro:   IPR002109
- InterPro:   IPR014025
- InterPro:   IPR011900
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF00462 Glutaredoxin [H]

EC number: NA

Molecular weight: Translated: 9603; Mature: 9472

Theoretical pI: Translated: 5.65; Mature: 5.65

Prosite motif: PS00195 GLUTAREDOXIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
8.0 %Met     (Translated Protein)
10.2 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
6.9 %Met     (Mature Protein)
9.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPNMPKVEMYTKWGCPYCFRAKQLLDGKGVSYEEIDVTMGGPKKTEMLERAPGHTTVPSI
CCCCCCEEEEEECCCCHHHHHHHHCCCCCCCEEEEEEEECCCCHHHHHHCCCCCCCCCEE
FIDGLHVGGSDDLAALNAQGKLDMMLGL
EECCEEECCCCCEEEECCCCCEEEEECC
>Mature Secondary Structure 
PNMPKVEMYTKWGCPYCFRAKQLLDGKGVSYEEIDVTMGGPKKTEMLERAPGHTTVPSI
CCCCCEEEEEECCCCHHHHHHHHCCCCCCCEEEEEEEECCCCHHHHHHCCCCCCCCCEE
FIDGLHVGGSDDLAALNAQGKLDMMLGL
EECCEEECCCCCEEEECCCCCEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]