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The map label for this gene is fnrA [H]

Identifier: 87200032

GI number: 87200032

Start: 2148509

End: 2149198

Strand: Reverse

Name: fnrA [H]

Synonym: Saro_2016

Alternate gene names: 87200032

Gene position: 2149198-2148509 (Counterclockwise)

Preceding gene: 87200033

Following gene: 87200029

Centisome position: 60.34

GC content: 67.1

Gene sequence:

>690_bases
ATGGACGCGGCGAGGCTGGCACAGGCACTGACGGCACAGAGCCTGTTCGCGGATTGCGAGCAGGCCGAGCTTTCGGACAT
CATCGGGCGCGGTCAGGTCCGAACCTTCAAGCCCGGCCAGGAACTCATGGCGCAGGGCGAGGAGGGCAAGACGCTCTTCA
TCGTGCTGAGCGGCCTTGCGCGCGTCAGCATGGTGGCCGCCAATGGTCGCGAAATCATCCTCGACTATGCCGAGGCGGGC
CATGTCCTGGGCGAGATCGCGTTTCTCGACGGCGGGGAACGGACGGCCTCGGTCGAGGCGATCGAGCCGGTCGAGGCGCT
GGTGCTGACGCGCAGCGCCTTTGCCGAGATCATCGACCGTCACAAGGGCCTGTCGCTGCGCCTGCTGAAGGCGATGGCGC
GGCGACTTCGCCAGAACAACGCGGTGATCGAAGCCGACAGGGCCTATACGTCCGGGCCGAGGCTTGCGCGGTTCCTGCTG
CGCCTGATGATGGGCGAGGGTTCGGATGCCGGGGCGCAGCTCAAGATCGCGCTGAGCCAGGGCGAACTGGGCAACTTCGC
CGGCATGTCGCGAGAGCAGATCAACCGGCAGCTTTCCGCCTGGGCCGAGAACGGCATCGTTGCGCTGAAGGGGGGCAGGG
TGACGATCCTCGACCGCGAGGCGCTGGTCGATGTCGCGGAGGCCTGGTAG

Upstream 100 bases:

>100_bases
GGCGCGTCTGGTTTAAAAAACGTGAAGGGGCTGGCCAGAGCCCCGGTTTGCTGATTATTTGCCGCCGGCCGCGGCTGTCG
CGGCAGGGGGCGAGACGGCG

Downstream 100 bases:

>100_bases
GCGCAGCGCTATTCCAGCGTGACCCGGCGCGTGATGGCGATGGCATCGAGGAACGCCACGTCGTGGCTTACCGCTATCAG
CGCGCCATCGTAGGCGGACA

Product: Crp/FNR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 229; Mature: 229

Protein sequence:

>229_residues
MDAARLAQALTAQSLFADCEQAELSDIIGRGQVRTFKPGQELMAQGEEGKTLFIVLSGLARVSMVAANGREIILDYAEAG
HVLGEIAFLDGGERTASVEAIEPVEALVLTRSAFAEIIDRHKGLSLRLLKAMARRLRQNNAVIEADRAYTSGPRLARFLL
RLMMGEGSDAGAQLKIALSQGELGNFAGMSREQINRQLSAWAENGIVALKGGRVTILDREALVDVAEAW

Sequences:

>Translated_229_residues
MDAARLAQALTAQSLFADCEQAELSDIIGRGQVRTFKPGQELMAQGEEGKTLFIVLSGLARVSMVAANGREIILDYAEAG
HVLGEIAFLDGGERTASVEAIEPVEALVLTRSAFAEIIDRHKGLSLRLLKAMARRLRQNNAVIEADRAYTSGPRLARFLL
RLMMGEGSDAGAQLKIALSQGELGNFAGMSREQINRQLSAWAENGIVALKGGRVTILDREALVDVAEAW
>Mature_229_residues
MDAARLAQALTAQSLFADCEQAELSDIIGRGQVRTFKPGQELMAQGEEGKTLFIVLSGLARVSMVAANGREIILDYAEAG
HVLGEIAFLDGGERTASVEAIEPVEALVLTRSAFAEIIDRHKGLSLRLLKAMARRLRQNNAVIEADRAYTSGPRLARFLL
RLMMGEGSDAGAQLKIALSQGELGNFAGMSREQINRQLSAWAENGIVALKGGRVTILDREALVDVAEAW

Specific function: Transcriptional regulator of arginine deiminase [H]

COG id: COG0664

COG function: function code T; cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH crp-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789756, Length=194, Percent_Identity=25.7731958762887, Blast_Score=71, Evalue=6e-14,
Organism=Escherichia coli, GI1787595, Length=209, Percent_Identity=23.444976076555, Blast_Score=65, Evalue=5e-12,
Organism=Drosophila melanogaster, GI45550482, Length=136, Percent_Identity=33.0882352941176, Blast_Score=65, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018490
- InterPro:   IPR000595
- InterPro:   IPR001808
- InterPro:   IPR012318
- InterPro:   IPR014710
- InterPro:   IPR018335
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00027 cNMP_binding; PF00325 Crp [H]

EC number: NA

Molecular weight: Translated: 24705; Mature: 24705

Theoretical pI: Translated: 5.17; Mature: 5.17

Prosite motif: PS50042 CNMP_BINDING_3 ; PS51063 HTH_CRP_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDAARLAQALTAQSLFADCEQAELSDIIGRGQVRTFKPGQELMAQGEEGKTLFIVLSGLA
CCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCHHHHHCCCCCCEEEEEEHHHH
RVSMVAANGREIILDYAEAGHVLGEIAFLDGGERTASVEAIEPVEALVLTRSAFAEIIDR
HHHHHCCCCCEEEEEHHHHCHHHHEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
HKGLSLRLLKAMARRLRQNNAVIEADRAYTSGPRLARFLLRLMMGEGSDAGAQLKIALSQ
CCCCHHHHHHHHHHHHHHCCCEEEECCCCCCCHHHHHHHHHHHHCCCCCCCCEEEEEECC
GELGNFAGMSREQINRQLSAWAENGIVALKGGRVTILDREALVDVAEAW
CCCCCCCCCCHHHHHHHHHHHHCCCEEEEECCEEEEEEHHHHHHHHHCC
>Mature Secondary Structure
MDAARLAQALTAQSLFADCEQAELSDIIGRGQVRTFKPGQELMAQGEEGKTLFIVLSGLA
CCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCHHHHHCCCCCCEEEEEEHHHH
RVSMVAANGREIILDYAEAGHVLGEIAFLDGGERTASVEAIEPVEALVLTRSAFAEIIDR
HHHHHCCCCCEEEEEHHHHCHHHHEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
HKGLSLRLLKAMARRLRQNNAVIEADRAYTSGPRLARFLLRLMMGEGSDAGAQLKIALSQ
CCCCHHHHHHHHHHHHHHCCCEEEECCCCCCCHHHHHHHHHHHHCCCCCCCCEEEEEECC
GELGNFAGMSREQINRQLSAWAENGIVALKGGRVTILDREALVDVAEAW
CCCCCCCCCCHHHHHHHHHHHHCCCEEEEECCEEEEEEHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8226670 [H]