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The map label for this gene is hflX [H]

Identifier: 87199949

GI number: 87199949

Start: 2046049

End: 2047329

Strand: Direct

Name: hflX [H]

Synonym: Saro_1932

Alternate gene names: 87199949

Gene position: 2046049-2047329 (Clockwise)

Preceding gene: 87199948

Following gene: 87199951

Centisome position: 57.45

GC content: 63.39

Gene sequence:

>1281_bases
GTGGTCGTCCTCCCCGATATTCGCCAGCGGGGAGGGGGCCTCGGCGCGGACGCCGAATCGCGTCTCGAAGAAGGGCAGGG
CCTTGCCCGCGCGATCGGCATCGAAGTCGTCGAGGCCTTCATTCTGCCCATCCGCACCGTGCGGCCCGCGACGCTTTTCG
GCGAAGGCCAGGTCGAGCGCATCGCTGTCGCCTGCAATCAGTCGGATGCGGAGCTGGTCATCGTTGATGGAGCCCTCTCC
GCCATCCAGCAGCGCAATCTCGAGGAAAAGCTCAAGCGCAAGGTCATCGATCGGACCGGCCTGATCCTCGAAATCTTCGG
CGAGCGCGCGGCAACGGCCGAGGGTCGGTTGCAGGTCGAACTTGCCCATCTTGATTACCAGGCCGGCCGGCTCGTACGCT
CGTGGACCCACCTCGAACGCCAGCGCGGCGGCTTCGGCTTTCTTGGCGGCCCCGGCGAAACCCAGATCGAAGCGGACCGC
CGCCTGATCCGCAATCGCATGGCACGCCTGCGGCGCGAACTTGAGCAGGTTCGCCGCACCCGTGGGCTTCATCGCGAACG
CCGCCAGCGCGCACCTTGGCCGGTCATTGCTCTCGTCGGCTATACCAACGCCGGCAAGTCCACGTTGTTCAATCGCCTCA
CCGGGGCCGATGTGATGGCCGAAGACCTGCTCTTCGCCACCCTCGACCCCACGATGCGTGCCATCCGCCTGCCTGGCGTG
GAAAAGGCCATTCTCTCGGACACGGTTGGCTTCATCTCGGACCTGCCGACGCAACTTGTCGCCGCTTTCCGCGCGACGCT
CGAGGAAGTTACAGCCGCCGACGTTATCGTCCACGTCCGCGACGTCGCCAACCTGGCATCCGCTGACCAGAAGGCAGAAG
TCGAACAGATTCTCGCCGACCTGGGCGTAATAGGGGAGGCCGGATCGACCATTCCAATCGTCGAGGCATGGAACAAGTGG
GATCTTCTGACGCCCGAAGAGCAGGCGATGCGGCAGGATCTAATTGCGGCAAAGATTGCCGAAGTGCCGGTCGTACCGAT
CTCGGCGCTGACGGGGGCAGGGGTCGAGACACTGCTCGACAAGCTTGGCGAAATGTTGACCGGGAGCGCGCAAACTCTGG
AACTGACAGTGCCCTTGTCGGATGGCCAGCGCTTGGCATGGCTTCACGCACACGGCGACATAATTTCGGAAAATCAAGTG
GATATTGCAGAAATTGGACCCGCGATGCGCATAAAGGTGCGCCTCACGCCACGGGAACTGGGGCGCTTTACCAGCCTGTG
A

Upstream 100 bases:

>100_bases
ATCTGACCGGGGACTGGGATGGCGAGGATTCCTGAGTACCTTTGAATTTGGCAACAACACCGGCGAGGTCGCCGGTGAAG
TAACCCGTGGCGCGCGCGCC

Downstream 100 bases:

>100_bases
CCTGCGCCGCCTCGGCTCGCTTCACAGCCTGCCAGAGCGCTTCCTGTTCATCGAGCGACAGCGTGGCGAATCGGCCATCA
GCCAGGGCCTCCATGGCGCC

Product: small GTP-binding protein domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 426; Mature: 426

Protein sequence:

>426_residues
MVVLPDIRQRGGGLGADAESRLEEGQGLARAIGIEVVEAFILPIRTVRPATLFGEGQVERIAVACNQSDAELVIVDGALS
AIQQRNLEEKLKRKVIDRTGLILEIFGERAATAEGRLQVELAHLDYQAGRLVRSWTHLERQRGGFGFLGGPGETQIEADR
RLIRNRMARLRRELEQVRRTRGLHRERRQRAPWPVIALVGYTNAGKSTLFNRLTGADVMAEDLLFATLDPTMRAIRLPGV
EKAILSDTVGFISDLPTQLVAAFRATLEEVTAADVIVHVRDVANLASADQKAEVEQILADLGVIGEAGSTIPIVEAWNKW
DLLTPEEQAMRQDLIAAKIAEVPVVPISALTGAGVETLLDKLGEMLTGSAQTLELTVPLSDGQRLAWLHAHGDIISENQV
DIAEIGPAMRIKVRLTPRELGRFTSL

Sequences:

>Translated_426_residues
MVVLPDIRQRGGGLGADAESRLEEGQGLARAIGIEVVEAFILPIRTVRPATLFGEGQVERIAVACNQSDAELVIVDGALS
AIQQRNLEEKLKRKVIDRTGLILEIFGERAATAEGRLQVELAHLDYQAGRLVRSWTHLERQRGGFGFLGGPGETQIEADR
RLIRNRMARLRRELEQVRRTRGLHRERRQRAPWPVIALVGYTNAGKSTLFNRLTGADVMAEDLLFATLDPTMRAIRLPGV
EKAILSDTVGFISDLPTQLVAAFRATLEEVTAADVIVHVRDVANLASADQKAEVEQILADLGVIGEAGSTIPIVEAWNKW
DLLTPEEQAMRQDLIAAKIAEVPVVPISALTGAGVETLLDKLGEMLTGSAQTLELTVPLSDGQRLAWLHAHGDIISENQV
DIAEIGPAMRIKVRLTPRELGRFTSL
>Mature_426_residues
MVVLPDIRQRGGGLGADAESRLEEGQGLARAIGIEVVEAFILPIRTVRPATLFGEGQVERIAVACNQSDAELVIVDGALS
AIQQRNLEEKLKRKVIDRTGLILEIFGERAATAEGRLQVELAHLDYQAGRLVRSWTHLERQRGGFGFLGGPGETQIEADR
RLIRNRMARLRRELEQVRRTRGLHRERRQRAPWPVIALVGYTNAGKSTLFNRLTGADVMAEDLLFATLDPTMRAIRLPGV
EKAILSDTVGFISDLPTQLVAAFRATLEEVTAADVIVHVRDVANLASADQKAEVEQILADLGVIGEAGSTIPIVEAWNKW
DLLTPEEQAMRQDLIAAKIAEVPVVPISALTGAGVETLLDKLGEMLTGSAQTLELTVPLSDGQRLAWLHAHGDIISENQV
DIAEIGPAMRIKVRLTPRELGRFTSL

Specific function: Unknown

COG id: COG2262

COG function: function code R; GTPases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 G (guanine nucleotide-binding) domain [H]

Homologues:

Organism=Homo sapiens, GI310133116, Length=299, Percent_Identity=35.7859531772575, Blast_Score=147, Evalue=2e-35,
Organism=Homo sapiens, GI310124269, Length=280, Percent_Identity=36.0714285714286, Blast_Score=145, Evalue=5e-35,
Organism=Homo sapiens, GI310124267, Length=280, Percent_Identity=36.0714285714286, Blast_Score=145, Evalue=5e-35,
Organism=Homo sapiens, GI310124171, Length=280, Percent_Identity=36.0714285714286, Blast_Score=145, Evalue=5e-35,
Organism=Homo sapiens, GI310124169, Length=280, Percent_Identity=36.0714285714286, Blast_Score=145, Evalue=5e-35,
Organism=Homo sapiens, GI310133118, Length=299, Percent_Identity=35.4515050167224, Blast_Score=145, Evalue=5e-35,
Organism=Escherichia coli, GI1790615, Length=362, Percent_Identity=45.0276243093923, Blast_Score=276, Evalue=3e-75,
Organism=Caenorhabditis elegans, GI17561038, Length=437, Percent_Identity=30.4347826086957, Blast_Score=161, Evalue=5e-40,
Organism=Drosophila melanogaster, GI24650079, Length=419, Percent_Identity=33.6515513126492, Blast_Score=177, Evalue=1e-44,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009022
- InterPro:   IPR016496
- InterPro:   IPR006073
- InterPro:   IPR002917 [H]

Pfam domain/function: PF01926 MMR_HSR1 [H]

EC number: NA

Molecular weight: Translated: 46606; Mature: 46606

Theoretical pI: Translated: 5.40; Mature: 5.40

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVVLPDIRQRGGGLGADAESRLEEGQGLARAIGIEVVEAFILPIRTVRPATLFGEGQVER
CEECCCHHHCCCCCCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCEEECCCCEEE
IAVACNQSDAELVIVDGALSAIQQRNLEEKLKRKVIDRTGLILEIFGERAATAEGRLQVE
EEEEECCCCCEEEEECHHHHHHHHCCHHHHHHHHHHHHCCCCEEECCCHHCCCCCEEEEE
LAHLDYQAGRLVRSWTHLERQRGGFGFLGGPGETQIEADRRLIRNRMARLRRELEQVRRT
EEECCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
RGLHRERRQRAPWPVIALVGYTNAGKSTLFNRLTGADVMAEDLLFATLDPTMRAIRLPGV
HCHHHHHHHCCCCCEEEEEECCCCCHHHHHHHHCCCHHHHHHHHHHHCCHHHHHHCCCCC
EKAILSDTVGFISDLPTQLVAAFRATLEEVTAADVIVHVRDVANLASADQKAEVEQILAD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHH
LGVIGEAGSTIPIVEAWNKWDLLTPEEQAMRQDLIAAKIAEVPVVPISALTGAGVETLLD
HCCCCCCCCCCCEEECCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCHHHHCCCCHHHHHH
KLGEMLTGSAQTLELTVPLSDGQRLAWLHAHGDIISENQVDIAEIGPAMRIKVRLTPREL
HHHHHHCCCCEEEEEEEEECCCCEEEEEEECCCCCCCCCCCHHHCCCEEEEEEEECHHHH
GRFTSL
HHHCCC
>Mature Secondary Structure
MVVLPDIRQRGGGLGADAESRLEEGQGLARAIGIEVVEAFILPIRTVRPATLFGEGQVER
CEECCCHHHCCCCCCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCEEECCCCEEE
IAVACNQSDAELVIVDGALSAIQQRNLEEKLKRKVIDRTGLILEIFGERAATAEGRLQVE
EEEEECCCCCEEEEECHHHHHHHHCCHHHHHHHHHHHHCCCCEEECCCHHCCCCCEEEEE
LAHLDYQAGRLVRSWTHLERQRGGFGFLGGPGETQIEADRRLIRNRMARLRRELEQVRRT
EEECCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
RGLHRERRQRAPWPVIALVGYTNAGKSTLFNRLTGADVMAEDLLFATLDPTMRAIRLPGV
HCHHHHHHHCCCCCEEEEEECCCCCHHHHHHHHCCCHHHHHHHHHHHCCHHHHHHCCCCC
EKAILSDTVGFISDLPTQLVAAFRATLEEVTAADVIVHVRDVANLASADQKAEVEQILAD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHH
LGVIGEAGSTIPIVEAWNKWDLLTPEEQAMRQDLIAAKIAEVPVVPISALTGAGVETLLD
HCCCCCCCCCCCEEECCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCHHHHCCCCHHHHHH
KLGEMLTGSAQTLELTVPLSDGQRLAWLHAHGDIISENQVDIAEIGPAMRIKVRLTPREL
HHHHHHCCCCEEEEEEEEECCCCEEEEEEECCCCCCCCCCCHHHCCCEEEEEEEECHHHH
GRFTSL
HHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8248183; 7610040; 9278503; 2020545; 3040675 [H]