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The map label for this gene is dltE [H]

Identifier: 87199828

GI number: 87199828

Start: 1910740

End: 1911462

Strand: Direct

Name: dltE [H]

Synonym: Saro_1811

Alternate gene names: 87199828

Gene position: 1910740-1911462 (Clockwise)

Preceding gene: 87199827

Following gene: 87199835

Centisome position: 53.65

GC content: 65.56

Gene sequence:

>723_bases
GTGGAGCTATCGGGAAAGACCGTGCTGGTGACCGGCGCGACGGACGGGATCGGCGCGCAGATCGCACGCCAGTTACGTAA
CAAGGGCGCGACGGTCATTGGGCAGGGCCGCACCCCGGCGCGGGTGGCGGCGGCGAGGGCCGATGGCTTTGAAATCGTCG
AGGCGGACCTATCCCTGCCGCAAGGCGTGGAAACGCTGATCTCGGCCATGGCAGGTCGCCAGATCGATGTGCTGGTCAAT
AATGCCGGGGCTGGAGTGGATCACGATTTCCGCGACGGTCAGCCCGATGCGGCGGCGGCGGATCGCACGATCTTCCTCAA
TCTCAATGCCCCCATTCACCTTATCACCGCGCTCATGCCTGGGCTGAAGGCACGGCCCGAGGCAATGATCGTCAACGTGA
CGTCCGGCCTCGCCATCGCGCCGCGTGCGGGTGGCCCGGTCTATTGCGCCACCAAGGCCGCGCTGCGCAGCTACACGCAG
GCTCTGCGCGCACAGTTGGCGGGAACCGGAGTGCATGTCGTCGAAGCCCTGCCGCCCGTCGTCGACACCCAACTCACCGC
GGGGCGCGGCAATCGCAAGATGCCTGCCGCCGAATGCGCACGCCAGATCGTCGACGGGATGGAGCGCAACGTAACCGAAA
TCAACATCGGGCTGGTCAAGGTTCTACAGGTCGTGAACTCGGTTTCCCCCGCCCTGGCACGGCGCATCATGCTGAAGTTC
TAG

Upstream 100 bases:

>100_bases
TCGATGGCGGAAGAACTCGTCCTGATGCGCTGAGCGGGCCGGTTGCAAGCCGCAACCGCCATGATACCCTGCCTTCCACC
AATCCAGGGGGAGGGCAGGC

Downstream 100 bases:

>100_bases
GACGCCGGAACGTGCCGTCTCACGCGGCACAGGTTCAGATGCCCGCGTACCACTGATAGCCGGAATGGTCCTCCCAGTAC
CCACCCTTGCCGCCGTGGAT

Product: short-chain dehydrogenase/reductase SDR

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 240; Mature: 240

Protein sequence:

>240_residues
MELSGKTVLVTGATDGIGAQIARQLRNKGATVIGQGRTPARVAAARADGFEIVEADLSLPQGVETLISAMAGRQIDVLVN
NAGAGVDHDFRDGQPDAAAADRTIFLNLNAPIHLITALMPGLKARPEAMIVNVTSGLAIAPRAGGPVYCATKAALRSYTQ
ALRAQLAGTGVHVVEALPPVVDTQLTAGRGNRKMPAAECARQIVDGMERNVTEINIGLVKVLQVVNSVSPALARRIMLKF

Sequences:

>Translated_240_residues
MELSGKTVLVTGATDGIGAQIARQLRNKGATVIGQGRTPARVAAARADGFEIVEADLSLPQGVETLISAMAGRQIDVLVN
NAGAGVDHDFRDGQPDAAAADRTIFLNLNAPIHLITALMPGLKARPEAMIVNVTSGLAIAPRAGGPVYCATKAALRSYTQ
ALRAQLAGTGVHVVEALPPVVDTQLTAGRGNRKMPAAECARQIVDGMERNVTEINIGLVKVLQVVNSVSPALARRIMLKF
>Mature_240_residues
MELSGKTVLVTGATDGIGAQIARQLRNKGATVIGQGRTPARVAAARADGFEIVEADLSLPQGVETLISAMAGRQIDVLVN
NAGAGVDHDFRDGQPDAAAADRTIFLNLNAPIHLITALMPGLKARPEAMIVNVTSGLAIAPRAGGPVYCATKAALRSYTQ
ALRAQLAGTGVHVVEALPPVVDTQLTAGRGNRKMPAAECARQIVDGMERNVTEINIGLVKVLQVVNSVSPALARRIMLKF

Specific function: Unknown

COG id: COG3967

COG function: function code M; Short-chain dehydrogenase involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI7705855, Length=194, Percent_Identity=26.8041237113402, Blast_Score=77, Evalue=1e-14,
Organism=Homo sapiens, GI226371731, Length=193, Percent_Identity=29.0155440414508, Blast_Score=75, Evalue=6e-14,
Organism=Homo sapiens, GI4557649, Length=192, Percent_Identity=26.5625, Blast_Score=72, Evalue=5e-13,
Organism=Homo sapiens, GI7705925, Length=187, Percent_Identity=33.6898395721925, Blast_Score=66, Evalue=3e-11,
Organism=Escherichia coli, GI1787820, Length=181, Percent_Identity=32.5966850828729, Blast_Score=87, Evalue=1e-18,
Organism=Escherichia coli, GI1786701, Length=184, Percent_Identity=28.2608695652174, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI87082100, Length=194, Percent_Identity=32.4742268041237, Blast_Score=66, Evalue=2e-12,
Organism=Escherichia coli, GI1787335, Length=192, Percent_Identity=29.1666666666667, Blast_Score=64, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17551412, Length=232, Percent_Identity=30.6034482758621, Blast_Score=79, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI115534694, Length=219, Percent_Identity=30.1369863013699, Blast_Score=75, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17562904, Length=230, Percent_Identity=31.7391304347826, Blast_Score=74, Evalue=8e-14,
Organism=Caenorhabditis elegans, GI17563726, Length=201, Percent_Identity=29.3532338308458, Blast_Score=72, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI17538480, Length=195, Percent_Identity=32.3076923076923, Blast_Score=71, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI72000259, Length=224, Percent_Identity=30.8035714285714, Blast_Score=70, Evalue=7e-13,
Organism=Caenorhabditis elegans, GI17560150, Length=251, Percent_Identity=30.2788844621514, Blast_Score=70, Evalue=7e-13,
Organism=Caenorhabditis elegans, GI17538486, Length=211, Percent_Identity=30.3317535545024, Blast_Score=69, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17560332, Length=199, Percent_Identity=30.1507537688442, Blast_Score=69, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17562990, Length=201, Percent_Identity=29.8507462686567, Blast_Score=66, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17562906, Length=214, Percent_Identity=31.7757009345794, Blast_Score=66, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6323882, Length=211, Percent_Identity=28.436018957346, Blast_Score=70, Evalue=2e-13,
Organism=Saccharomyces cerevisiae, GI6322227, Length=200, Percent_Identity=27.5, Blast_Score=64, Evalue=2e-11,
Organism=Drosophila melanogaster, GI23397609, Length=192, Percent_Identity=36.9791666666667, Blast_Score=76, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24643142, Length=199, Percent_Identity=35.678391959799, Blast_Score=74, Evalue=7e-14,
Organism=Drosophila melanogaster, GI24584744, Length=194, Percent_Identity=27.319587628866, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI28574402, Length=194, Percent_Identity=27.319587628866, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI21358495, Length=279, Percent_Identity=25.8064516129032, Blast_Score=69, Evalue=3e-12,
Organism=Drosophila melanogaster, GI161076933, Length=194, Percent_Identity=26.2886597938144, Blast_Score=68, Evalue=4e-12,
Organism=Drosophila melanogaster, GI24584748, Length=194, Percent_Identity=26.2886597938144, Blast_Score=68, Evalue=5e-12,
Organism=Drosophila melanogaster, GI24640442, Length=196, Percent_Identity=26.530612244898, Blast_Score=65, Evalue=3e-11,

Paralogues:

None

Copy number: 1300 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 25027; Mature: 25027

Theoretical pI: Translated: 10.06; Mature: 10.06

Prosite motif: PS00061 ADH_SHORT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MELSGKTVLVTGATDGIGAQIARQLRNKGATVIGQGRTPARVAAARADGFEIVEADLSLP
CCCCCCEEEEECCCCCHHHHHHHHHHHCCCEEEECCCCCHHHHHHCCCCCEEEEECCCCC
QGVETLISAMAGRQIDVLVNNAGAGVDHDFRDGQPDAAAADRTIFLNLNAPIHLITALMP
CCHHHHHHHHCCCEEEEEEECCCCCCCCCCCCCCCCCCCCCCEEEEECCCHHHHHHHHHC
GLKARPEAMIVNVTSGLAIAPRAGGPVYCATKAALRSYTQALRAQLAGTGVHVVEALPPV
CCCCCCCEEEEEECCCEEECCCCCCCEEEHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCH
VDTQLTAGRGNRKMPAAECARQIVDGMERNVTEINIGLVKVLQVVNSVSPALARRIMLKF
HCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHCC
>Mature Secondary Structure
MELSGKTVLVTGATDGIGAQIARQLRNKGATVIGQGRTPARVAAARADGFEIVEADLSLP
CCCCCCEEEEECCCCCHHHHHHHHHHHCCCEEEECCCCCHHHHHHCCCCCEEEEECCCCC
QGVETLISAMAGRQIDVLVNNAGAGVDHDFRDGQPDAAAADRTIFLNLNAPIHLITALMP
CCHHHHHHHHCCCEEEEEEECCCCCCCCCCCCCCCCCCCCCCEEEEECCCHHHHHHHHHC
GLKARPEAMIVNVTSGLAIAPRAGGPVYCATKAALRSYTQALRAQLAGTGVHVVEALPPV
CCCCCCCEEEEEECCCEEECCCCCCCEEEHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCH
VDTQLTAGRGNRKMPAAECARQIVDGMERNVTEINIGLVKVLQVVNSVSPALARRIMLKF
HCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7934828; 9384377; 7797557 [H]