BacMap

Definition	Novosphingobium aromaticivorans DSM 12444 chromosome, complete genome.
Accession	NC_007794
Length	3,561,584

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The map label for this gene is bdhA [H]

Identifier: 87199767

GI number: 87199767

Start: 1844153

End: 1844938

Strand: Direct

Name: bdhA [H]

Synonym: Saro_1750

Alternate gene names: 87199767

Gene position: 1844153-1844938 (Clockwise)

Preceding gene: 87199764

Following gene: 87199768

Centisome position: 51.78

GC content: 65.78

Gene sequence:

>786_bases
ATGTTCCTGAAGGACAAGTGTGCGCTTGTGACTGGCTCGACCTCGGGCATCGGCCTTGCCTATGCGCGGGCTCTCGCGGC
GGAAGGGGCGCATATCGTTCTCAACGGCTTCGGCGATCCGGCCGAGATCGAGGCGCTTTGCCGGGAACTCGCCGACGCCA
GCGGCGGACGAGCGATCTTTGCGGCGGGGGATCTTACGCGGCGCGAGGGCACCGAGGCGATGATGGCGACGGCGCTGGCC
GAATTCGGCGCGGTGGACATCCTGATCAACAACGCCGGCATGCAGCACGTGGCGCCGGTCGAGGAGTTCCCGGTCGAGAA
GTGGGATGCGATCATCGCGCTCAACCTCACGTCGGCCTTCGATGCCTGCCGGCTCGCAATTCCGGGGATGAAGGCCAAGG
GCTGGGGGCGCATCATCTTCACGGCTTCTGCCCACTCGCTCACGGCATCGCCGTTCAAGGCGGCCTATGTCTCGGCAAAG
CACGGGATCGCAGGGCTGACGAAGACGCTGGCGCTGGAACTGGCGACGCATGGGGTGACCGCCAACTGCATCAGCCCCGG
CTATGTCTGGACTCCGCTGGTCGAGAACCAGATCCCCGACACGATGAAGGCGCGGGGGATGACGCGCGAGCAGGTGATCA
ACGACGTGCTGCTGACCCGCCAGCCGACCAAGCAGTTCGTCCAGCCCGAGGACGTGGCCGCGCTGGCGCTGTTCCTGTGC
CGGCACGAGGCGCGCAACATCACCGGTGCGAACTACAACATGGATGGTGGCTGGGTGGCGGAATAA

Upstream 100 bases:

>100_bases
CGCATTGCATGCCCCTTCATACCTATTTGCGACTGGACAAGCGCGACTTCGCCCGCGATGCCAATCCGATCTACCTATCC
AGAATCTCCGGAGTTGGCGA

Downstream 100 bases:

>100_bases
GGCGTCCGGCACCGCTCGTCGTAAAGTTCTGTTCATCCGGCGCGGCCCAATTGGGAACTTGCGTCGGGCTCCGGGTTTTG
AGAGCAAGGGCGTGCGACGA

Product: 3-hydroxybutyrate dehydrogenase

Products: NA

Alternate protein names: BDH; 3-hydroxybutyrate dehydrogenase; 3-HBDH [H]

Number of amino acids: Translated: 261; Mature: 261

Protein sequence:

>261_residues
MFLKDKCALVTGSTSGIGLAYARALAAEGAHIVLNGFGDPAEIEALCRELADASGGRAIFAAGDLTRREGTEAMMATALA
EFGAVDILINNAGMQHVAPVEEFPVEKWDAIIALNLTSAFDACRLAIPGMKAKGWGRIIFTASAHSLTASPFKAAYVSAK
HGIAGLTKTLALELATHGVTANCISPGYVWTPLVENQIPDTMKARGMTREQVINDVLLTRQPTKQFVQPEDVAALALFLC
RHEARNITGANYNMDGGWVAE

Sequences:

>Translated_261_residues
MFLKDKCALVTGSTSGIGLAYARALAAEGAHIVLNGFGDPAEIEALCRELADASGGRAIFAAGDLTRREGTEAMMATALA
EFGAVDILINNAGMQHVAPVEEFPVEKWDAIIALNLTSAFDACRLAIPGMKAKGWGRIIFTASAHSLTASPFKAAYVSAK
HGIAGLTKTLALELATHGVTANCISPGYVWTPLVENQIPDTMKARGMTREQVINDVLLTRQPTKQFVQPEDVAALALFLC
RHEARNITGANYNMDGGWVAE
>Mature_261_residues
MFLKDKCALVTGSTSGIGLAYARALAAEGAHIVLNGFGDPAEIEALCRELADASGGRAIFAAGDLTRREGTEAMMATALA
EFGAVDILINNAGMQHVAPVEEFPVEKWDAIIALNLTSAFDACRLAIPGMKAKGWGRIIFTASAHSLTASPFKAAYVSAK
HGIAGLTKTLALELATHGVTANCISPGYVWTPLVENQIPDTMKARGMTREQVINDVLLTRQPTKQFVQPEDVAALALFLC
RHEARNITGANYNMDGGWVAE

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI32483357, Length=256, Percent_Identity=30.859375, Blast_Score=118, Evalue=5e-27,
Organism=Homo sapiens, GI4504505, Length=263, Percent_Identity=30.0380228136882, Blast_Score=103, Evalue=1e-22,
Organism=Homo sapiens, GI59889578, Length=216, Percent_Identity=31.9444444444444, Blast_Score=99, Evalue=5e-21,
Organism=Homo sapiens, GI19923817, Length=260, Percent_Identity=27.6923076923077, Blast_Score=99, Evalue=5e-21,
Organism=Homo sapiens, GI66933014, Length=236, Percent_Identity=30.0847457627119, Blast_Score=96, Evalue=4e-20,
Organism=Homo sapiens, GI7705925, Length=259, Percent_Identity=30.8880308880309, Blast_Score=95, Evalue=6e-20,
Organism=Homo sapiens, GI20149619, Length=253, Percent_Identity=29.2490118577075, Blast_Score=95, Evalue=8e-20,
Organism=Homo sapiens, GI5031737, Length=258, Percent_Identity=28.6821705426357, Blast_Score=91, Evalue=1e-18,
Organism=Homo sapiens, GI126723750, Length=259, Percent_Identity=28.1853281853282, Blast_Score=90, Evalue=3e-18,
Organism=Homo sapiens, GI7706318, Length=199, Percent_Identity=29.1457286432161, Blast_Score=89, Evalue=4e-18,
Organism=Homo sapiens, GI15277342, Length=269, Percent_Identity=27.8810408921933, Blast_Score=89, Evalue=5e-18,
Organism=Homo sapiens, GI33667109, Length=194, Percent_Identity=32.9896907216495, Blast_Score=86, Evalue=3e-17,
Organism=Homo sapiens, GI31542939, Length=241, Percent_Identity=28.2157676348548, Blast_Score=86, Evalue=4e-17,
Organism=Homo sapiens, GI126723191, Length=186, Percent_Identity=29.5698924731183, Blast_Score=84, Evalue=1e-16,
Organism=Homo sapiens, GI4758504, Length=204, Percent_Identity=30.8823529411765, Blast_Score=83, Evalue=3e-16,
Organism=Homo sapiens, GI10190704, Length=259, Percent_Identity=25.8687258687259, Blast_Score=79, Evalue=4e-15,
Organism=Homo sapiens, GI142976729, Length=236, Percent_Identity=30.0847457627119, Blast_Score=79, Evalue=5e-15,
Organism=Homo sapiens, GI109715829, Length=248, Percent_Identity=29.0322580645161, Blast_Score=75, Evalue=5e-14,
Organism=Homo sapiens, GI7657478, Length=188, Percent_Identity=27.6595744680851, Blast_Score=73, Evalue=2e-13,
Organism=Homo sapiens, GI223718074, Length=193, Percent_Identity=27.979274611399, Blast_Score=71, Evalue=8e-13,
Organism=Homo sapiens, GI83715985, Length=189, Percent_Identity=30.1587301587302, Blast_Score=71, Evalue=1e-12,
Organism=Homo sapiens, GI224922801, Length=176, Percent_Identity=28.4090909090909, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI226371731, Length=191, Percent_Identity=27.2251308900524, Blast_Score=67, Evalue=1e-11,
Organism=Homo sapiens, GI40254992, Length=254, Percent_Identity=23.2283464566929, Blast_Score=66, Evalue=3e-11,
Organism=Homo sapiens, GI4503301, Length=217, Percent_Identity=26.2672811059908, Blast_Score=65, Evalue=7e-11,
Organism=Escherichia coli, GI1789208, Length=260, Percent_Identity=31.5384615384615, Blast_Score=119, Evalue=2e-28,
Organism=Escherichia coli, GI1787335, Length=258, Percent_Identity=31.3953488372093, Blast_Score=118, Evalue=3e-28,
Organism=Escherichia coli, GI87082100, Length=256, Percent_Identity=32.421875, Blast_Score=118, Evalue=4e-28,
Organism=Escherichia coli, GI87082160, Length=258, Percent_Identity=31.3953488372093, Blast_Score=116, Evalue=1e-27,
Organism=Escherichia coli, GI1788459, Length=255, Percent_Identity=30.9803921568627, Blast_Score=113, Evalue=1e-26,
Organism=Escherichia coli, GI1790717, Length=255, Percent_Identity=28.2352941176471, Blast_Score=112, Evalue=2e-26,
Organism=Escherichia coli, GI1789378, Length=256, Percent_Identity=29.296875, Blast_Score=97, Evalue=1e-21,
Organism=Escherichia coli, GI1787905, Length=265, Percent_Identity=28.6792452830189, Blast_Score=95, Evalue=6e-21,
Organism=Escherichia coli, GI2367175, Length=255, Percent_Identity=29.4117647058824, Blast_Score=89, Evalue=3e-19,
Organism=Escherichia coli, GI1789057, Length=259, Percent_Identity=28.1853281853282, Blast_Score=85, Evalue=4e-18,
Organism=Escherichia coli, GI2367365, Length=253, Percent_Identity=26.8774703557312, Blast_Score=78, Evalue=6e-16,
Organism=Escherichia coli, GI1786701, Length=197, Percent_Identity=27.4111675126904, Blast_Score=72, Evalue=3e-14,
Organism=Escherichia coli, GI1787820, Length=182, Percent_Identity=28.5714285714286, Blast_Score=68, Evalue=5e-13,
Organism=Escherichia coli, GI1786812, Length=263, Percent_Identity=26.2357414448669, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1787526, Length=259, Percent_Identity=23.1660231660232, Blast_Score=65, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI17560676, Length=261, Percent_Identity=31.0344827586207, Blast_Score=110, Evalue=7e-25,
Organism=Caenorhabditis elegans, GI17560332, Length=268, Percent_Identity=31.3432835820896, Blast_Score=98, Evalue=4e-21,
Organism=Caenorhabditis elegans, GI17561402, Length=256, Percent_Identity=28.125, Blast_Score=97, Evalue=6e-21,
Organism=Caenorhabditis elegans, GI17562910, Length=272, Percent_Identity=29.4117647058824, Blast_Score=95, Evalue=4e-20,
Organism=Caenorhabditis elegans, GI17559104, Length=263, Percent_Identity=28.8973384030418, Blast_Score=94, Evalue=6e-20,
Organism=Caenorhabditis elegans, GI17568967, Length=233, Percent_Identity=28.3261802575107, Blast_Score=92, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI17538486, Length=268, Percent_Identity=28.7313432835821, Blast_Score=87, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI17531453, Length=269, Percent_Identity=30.8550185873606, Blast_Score=85, Evalue=3e-17,
Organism=Caenorhabditis elegans, GI71994600, Length=257, Percent_Identity=28.0155642023346, Blast_Score=84, Evalue=8e-17,
Organism=Caenorhabditis elegans, GI17538480, Length=266, Percent_Identity=27.8195488721804, Blast_Score=84, Evalue=9e-17,
Organism=Caenorhabditis elegans, GI17544670, Length=270, Percent_Identity=30, Blast_Score=83, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17551412, Length=269, Percent_Identity=28.2527881040892, Blast_Score=82, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI71994604, Length=256, Percent_Identity=27.734375, Blast_Score=82, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI17555706, Length=258, Percent_Identity=25.968992248062, Blast_Score=81, Evalue=6e-16,
Organism=Caenorhabditis elegans, GI17560150, Length=266, Percent_Identity=28.9473684210526, Blast_Score=81, Evalue=7e-16,
Organism=Caenorhabditis elegans, GI72000259, Length=267, Percent_Identity=27.7153558052434, Blast_Score=80, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17562906, Length=266, Percent_Identity=28.9473684210526, Blast_Score=79, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17562908, Length=266, Percent_Identity=28.5714285714286, Blast_Score=77, Evalue=6e-15,
Organism=Caenorhabditis elegans, GI25147288, Length=263, Percent_Identity=25.8555133079848, Blast_Score=77, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17562990, Length=266, Percent_Identity=27.4436090225564, Blast_Score=76, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17563726, Length=272, Percent_Identity=26.1029411764706, Blast_Score=75, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI17538182, Length=213, Percent_Identity=30.5164319248826, Blast_Score=75, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI193204405, Length=267, Percent_Identity=29.9625468164794, Blast_Score=75, Evalue=5e-14,
Organism=Caenorhabditis elegans, GI17562904, Length=269, Percent_Identity=26.0223048327138, Blast_Score=74, Evalue=7e-14,
Organism=Caenorhabditis elegans, GI17560220, Length=265, Percent_Identity=29.4339622641509, Blast_Score=74, Evalue=9e-14,
Organism=Caenorhabditis elegans, GI17565030, Length=268, Percent_Identity=27.6119402985075, Blast_Score=68, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI115534694, Length=256, Percent_Identity=25, Blast_Score=67, Evalue=9e-12,
Organism=Caenorhabditis elegans, GI17564282, Length=189, Percent_Identity=27.5132275132275, Blast_Score=67, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI71982365, Length=207, Percent_Identity=27.0531400966184, Blast_Score=66, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17536651, Length=262, Percent_Identity=24.8091603053435, Blast_Score=65, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI193203115, Length=195, Percent_Identity=28.2051282051282, Blast_Score=65, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI193203117, Length=192, Percent_Identity=28.6458333333333, Blast_Score=64, Evalue=7e-11,
Organism=Caenorhabditis elegans, GI17536025, Length=262, Percent_Identity=24.4274809160305, Blast_Score=64, Evalue=8e-11,
Organism=Saccharomyces cerevisiae, GI6322861, Length=266, Percent_Identity=29.3233082706767, Blast_Score=108, Evalue=7e-25,
Organism=Saccharomyces cerevisiae, GI6322227, Length=212, Percent_Identity=26.8867924528302, Blast_Score=74, Evalue=2e-14,
Organism=Saccharomyces cerevisiae, GI6324126, Length=259, Percent_Identity=23.5521235521236, Blast_Score=70, Evalue=4e-13,
Organism=Saccharomyces cerevisiae, GI6322226, Length=209, Percent_Identity=29.6650717703349, Blast_Score=69, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24644339, Length=260, Percent_Identity=30.7692307692308, Blast_Score=115, Evalue=3e-26,
Organism=Drosophila melanogaster, GI23397609, Length=259, Percent_Identity=30.8880308880309, Blast_Score=102, Evalue=2e-22,
Organism=Drosophila melanogaster, GI21357041, Length=258, Percent_Identity=28.2945736434109, Blast_Score=102, Evalue=2e-22,
Organism=Drosophila melanogaster, GI28571526, Length=258, Percent_Identity=29.8449612403101, Blast_Score=101, Evalue=5e-22,
Organism=Drosophila melanogaster, GI18859837, Length=265, Percent_Identity=29.0566037735849, Blast_Score=98, Evalue=5e-21,
Organism=Drosophila melanogaster, GI21355319, Length=261, Percent_Identity=27.9693486590038, Blast_Score=96, Evalue=3e-20,
Organism=Drosophila melanogaster, GI24639444, Length=259, Percent_Identity=26.6409266409266, Blast_Score=88, Evalue=5e-18,
Organism=Drosophila melanogaster, GI21358495, Length=256, Percent_Identity=26.5625, Blast_Score=87, Evalue=8e-18,
Organism=Drosophila melanogaster, GI17737361, Length=205, Percent_Identity=29.2682926829268, Blast_Score=82, Evalue=3e-16,
Organism=Drosophila melanogaster, GI24643142, Length=267, Percent_Identity=26.9662921348315, Blast_Score=79, Evalue=4e-15,
Organism=Drosophila melanogaster, GI24640442, Length=201, Percent_Identity=29.8507462686567, Blast_Score=72, Evalue=4e-13,
Organism=Drosophila melanogaster, GI24584744, Length=191, Percent_Identity=27.7486910994764, Blast_Score=70, Evalue=1e-12,
Organism=Drosophila melanogaster, GI28574402, Length=191, Percent_Identity=28.2722513089005, Blast_Score=70, Evalue=1e-12,
Organism=Drosophila melanogaster, GI161076933, Length=202, Percent_Identity=28.2178217821782, Blast_Score=69, Evalue=4e-12,
Organism=Drosophila melanogaster, GI24584748, Length=202, Percent_Identity=28.2178217821782, Blast_Score=69, Evalue=4e-12,
Organism=Drosophila melanogaster, GI21357673, Length=246, Percent_Identity=25.2032520325203, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI21356301, Length=199, Percent_Identity=27.1356783919598, Blast_Score=65, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011294
- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: =1.1.1.30 [H]

Molecular weight: Translated: 27701; Mature: 27701

Theoretical pI: Translated: 5.95; Mature: 5.95

Prosite motif: PS00061 ADH_SHORT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFLKDKCALVTGSTSGIGLAYARALAAEGAHIVLNGFGDPAEIEALCRELADASGGRAIF
CCCCCCEEEEECCCCCCHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHHCCCCCEEEE
AAGDLTRREGTEAMMATALAEFGAVDILINNAGMQHVAPVEEFPVEKWDAIIALNLTSAF
EECCCCHHCCHHHHHHHHHHHCCEEEEEEECCCCCCCCCHHHCCCCCCCEEEEEEEHHHH
DACRLAIPGMKAKGWGRIIFTASAHSLTASPFKAAYVSAKHGIAGLTKTLALELATHGVT
HHHHHCCCCCCCCCCEEEEEEECCCCCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHCCCE
ANCISPGYVWTPLVENQIPDTMKARGMTREQVINDVLLTRQPTKQFVQPEDVAALALFLC
EECCCCCCEECCHHHCCCCCHHHHCCCCHHHHHHHHHHCCCCHHHHCCCHHHHHHHHHHH
RHEARNITGANYNMDGGWVAE
HHHHCCCCCCCCCCCCCEECC
>Mature Secondary Structure
MFLKDKCALVTGSTSGIGLAYARALAAEGAHIVLNGFGDPAEIEALCRELADASGGRAIF
CCCCCCEEEEECCCCCCHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHHCCCCCEEEE
AAGDLTRREGTEAMMATALAEFGAVDILINNAGMQHVAPVEEFPVEKWDAIIALNLTSAF
EECCCCHHCCHHHHHHHHHHHCCEEEEEEECCCCCCCCCHHHCCCCCCCEEEEEEEHHHH
DACRLAIPGMKAKGWGRIIFTASAHSLTASPFKAAYVSAKHGIAGLTKTLALELATHGVT
HHHHHCCCCCCCCCCEEEEEEECCCCCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHCCCE
ANCISPGYVWTPLVENQIPDTMKARGMTREQVINDVLLTRQPTKQFVQPEDVAALALFLC
EECCCCCCEECCHHHCCCCCHHHHCCCCHHHHHHHHHHCCCCHHHHCCCHHHHHHHHHHH
RHEARNITGANYNMDGGWVAE
HHHHCCCCCCCCCCCCCEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9922248; 11481431 [H]