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The map label for this gene is oxyR [H]

Identifier: 87199663

GI number: 87199663

Start: 1722084

End: 1722953

Strand: Direct

Name: oxyR [H]

Synonym: Saro_1646

Alternate gene names: 87199663

Gene position: 1722084-1722953 (Clockwise)

Preceding gene: 87199656

Following gene: 87199666

Centisome position: 48.35

GC content: 68.51

Gene sequence:

>870_bases
ATGATGAAACGAGCCCAGCTCCGCCACTTCCTGGCGCTTGTCGAAAGCGGCAACTTCACCCGCGCGGCGGAGCGGCTGGC
GATCTCGCAGCCCACGCTTTCCGCCTCGATCGCCGAACTCGAACGGATGGCCGGCACACGTCTGTTCCTGCGCGAGAAGC
GGCAGGTCCGCCTGACTGCGGCTGGCGCGCGGCTCGTCAACCATGCGCGGGCAATCGAGCGCGAGTTCCGGGCTGCCGAA
GCAGCCTTCGTCGAAGCCCCGGTACCACTGGCGCCGCTGCGACTGGGCACGATACCGTCGGTGTCGACCGCGATGCTTTC
CGCGGCGGTGCGGCGCTGGACCGGCCCTCAGCCGCTGACGCTGGTTGAAGGCACGGATGCAGAATTGCGGCGCAAGCTGG
GCGAGGGGCAGGTCGATGTCATCCTTACGCTGCTACGCCCCGAGGATGCGGACCGTCCATCGCTGCGACTGCTGGAGGAG
GGGTATCGCCTGCTCCTGCCGGAAAGCCACGCCCTGGCAGGGGCTGCGCTGATCGATGCGCGCGACGTTGCGTCCGAGAC
GATGATCGCGCGCCGTTCGTGCGAGATCCTGGGGGAGACCAGCCGCTGGTTCACCCAACGCGGCGTGCGCCCGCCGTTCT
TCCTGCGCTCTTCGAACGACGATCGATGCATCGAGATGGTGCGGGCGGGGATGGGAGTCACCACCGCGCCGCAATCGCTG
GCGCGGGACGGAGTCGTGGCGGTACAGCTTGCCGATTACGATTTCCGGCGGACGCTCGGCCTTGTCGGCGGACGCGACCG
GCCGGACCTTGTGGCAGAGGAGGGCGCGCTTGCCGAAGCGCTGCGCGCCGCGTTCTACTTCACGGCGTAG

Upstream 100 bases:

>100_bases
ATTTCGGCATCCTCTCGCAACTCTTTTCGGGGCCAACGATACCATTGCCAAAGTCGCGATCAAAATTGATTTGATCCGGG
ATTTGCGATAGATTTTTCCT

Downstream 100 bases:

>100_bases
AGCAGGCGCCCTTCGCCGAGGCGTTCCAGGACGCCCGAAATGTCGTCGTTCGAGAAGGCGAAGCAGCCCTGGCTGCGACC
GATCCGGCCCTGCGTACGGG

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: Morphology and auto-aggregation control protein [H]

Number of amino acids: Translated: 289; Mature: 289

Protein sequence:

>289_residues
MMKRAQLRHFLALVESGNFTRAAERLAISQPTLSASIAELERMAGTRLFLREKRQVRLTAAGARLVNHARAIEREFRAAE
AAFVEAPVPLAPLRLGTIPSVSTAMLSAAVRRWTGPQPLTLVEGTDAELRRKLGEGQVDVILTLLRPEDADRPSLRLLEE
GYRLLLPESHALAGAALIDARDVASETMIARRSCEILGETSRWFTQRGVRPPFFLRSSNDDRCIEMVRAGMGVTTAPQSL
ARDGVVAVQLADYDFRRTLGLVGGRDRPDLVAEEGALAEALRAAFYFTA

Sequences:

>Translated_289_residues
MMKRAQLRHFLALVESGNFTRAAERLAISQPTLSASIAELERMAGTRLFLREKRQVRLTAAGARLVNHARAIEREFRAAE
AAFVEAPVPLAPLRLGTIPSVSTAMLSAAVRRWTGPQPLTLVEGTDAELRRKLGEGQVDVILTLLRPEDADRPSLRLLEE
GYRLLLPESHALAGAALIDARDVASETMIARRSCEILGETSRWFTQRGVRPPFFLRSSNDDRCIEMVRAGMGVTTAPQSL
ARDGVVAVQLADYDFRRTLGLVGGRDRPDLVAEEGALAEALRAAFYFTA
>Mature_289_residues
MMKRAQLRHFLALVESGNFTRAAERLAISQPTLSASIAELERMAGTRLFLREKRQVRLTAAGARLVNHARAIEREFRAAE
AAFVEAPVPLAPLRLGTIPSVSTAMLSAAVRRWTGPQPLTLVEGTDAELRRKLGEGQVDVILTLLRPEDADRPSLRLLEE
GYRLLLPESHALAGAALIDARDVASETMIARRSCEILGETSRWFTQRGVRPPFFLRSSNDDRCIEMVRAGMGVTTAPQSL
ARDGVVAVQLADYDFRRTLGLVGGRDRPDLVAEEGALAEALRAAFYFTA

Specific function: Hydrogen peroxide sensor. Activates the expression of a regulon of hydrogen peroxide-inducible genes such as katG, gor, ahpC, ahpF, oxyS (a regulatory RNA), dps, fur and grxA. OxyR expression is negatively autoregulated by binding to a 43 bp region upstre

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1790399, Length=292, Percent_Identity=30.4794520547945, Blast_Score=99, Evalue=2e-22,
Organism=Escherichia coli, GI1788887, Length=247, Percent_Identity=31.5789473684211, Blast_Score=92, Evalue=3e-20,
Organism=Escherichia coli, GI157672245, Length=289, Percent_Identity=25.9515570934256, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI1787601, Length=180, Percent_Identity=29.4444444444444, Blast_Score=71, Evalue=7e-14,
Organism=Escherichia coli, GI2367136, Length=256, Percent_Identity=26.953125, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI145693105, Length=279, Percent_Identity=24.3727598566308, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1788297, Length=172, Percent_Identity=34.3023255813954, Blast_Score=66, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 31759; Mature: 31759

Theoretical pI: Translated: 9.73; Mature: 9.73

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMKRAQLRHFLALVESGNFTRAAERLAISQPTLSASIAELERMAGTRLFLREKRQVRLTA
CCCHHHHHHHHHHHHCCCHHHHHHHHHHCCCCHHHHHHHHHHHHCHHHHHHHCHHEEEHH
AGARLVNHARAIEREFRAAEAAFVEAPVPLAPLRLGTIPSVSTAMLSAAVRRWTGPQPLT
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCEE
LVEGTDAELRRKLGEGQVDVILTLLRPEDADRPSLRLLEEGYRLLLPESHALAGAALIDA
EECCCCHHHHHHHCCCCEEEEEEEECCCCCCCHHHHHHHCCCEEECCCCHHHHHHHHHHH
RDVASETMIARRSCEILGETSRWFTQRGVRPPFFLRSSNDDRCIEMVRAGMGVTTAPQSL
HHHHHHHHHHHHHHHHHCCHHHHHHHCCCCCCEEEECCCCHHHHHHHHHCCCCCCCCHHH
ARDGVVAVQLADYDFRRTLGLVGGRDRPDLVAEEGALAEALRAAFYFTA
HCCCEEEEEECCCHHHHHHHHCCCCCCCCHHHCCCHHHHHHHHHHHCCC
>Mature Secondary Structure
MMKRAQLRHFLALVESGNFTRAAERLAISQPTLSASIAELERMAGTRLFLREKRQVRLTA
CCCHHHHHHHHHHHHCCCHHHHHHHHHHCCCCHHHHHHHHHHHHCHHHHHHHCHHEEEHH
AGARLVNHARAIEREFRAAEAAFVEAPVPLAPLRLGTIPSVSTAMLSAAVRRWTGPQPLT
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCEE
LVEGTDAELRRKLGEGQVDVILTLLRPEDADRPSLRLLEEGYRLLLPESHALAGAALIDA
EECCCCHHHHHHHCCCCEEEEEEEECCCCCCCHHHHHHHCCCEEECCCCHHHHHHHHHHH
RDVASETMIARRSCEILGETSRWFTQRGVRPPFFLRSSNDDRCIEMVRAGMGVTTAPQSL
HHHHHHHHHHHHHHHHHCCHHHHHHHCCCCCCEEEECCCCHHHHHHHHHCCCCCCCCHHH
ARDGVVAVQLADYDFRRTLGLVGGRDRPDLVAEEGALAEALRAAFYFTA
HCCCEEEEEECCCHHHHHHHHCCCCCCCCHHHCCCHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]