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The map label for this gene is mcpA [H]

Identifier: 87199451

GI number: 87199451

Start: 1471981

End: 1473426

Strand: Direct

Name: mcpA [H]

Synonym: Saro_1430

Alternate gene names: 87199451

Gene position: 1471981-1473426 (Clockwise)

Preceding gene: 87199450

Following gene: 87199456

Centisome position: 41.33

GC content: 63.55

Gene sequence:

>1446_bases
ATGGATACCGCACACACCGGTCAGGACGTTGCCCGCAAGCTTGCGTTCTTCAATATCGACCACAAGGATTTCGAGCGGTT
TCCGCACATCGCTAAAGTGCTTGAAAACTACGCTCCCCCCGCACTCGACAAGCTTTACGACCAGATCGCTACAACGCCGG
AGACGGCGAGCTTCTTTGGCTCTCGGCAGGCCATGCGCCATGCGCGCGACAAGCAGATCGAGCATTGGGCGGGTATGTTC
AGCGGTCGTGCCGACCGCTCCTATTTCGAGAGCGCCGAGCGGATCGGCAACGTCCACGCGCGGATCGGCCTAGAGCCAGG
CTGGTACATTGGCGGCTACGCGATGGTGCTGGAGCAGGTCATCAACGCAATGTTCTCCGGCATCGGGGGCATACTGGGCG
CGAAGCGGACGGCGCGATCCGTCGGCTCGCTCGTCAAGATGGCATTGCTGGATATGGAAGTGGCCCTGTCCACCTATTTC
AGGGCCGAGGAAGCCGCCCGCGTGGCCGTGATCGACGAGGTCAGCGCCACCTTGCGGGGCATGGCTGACGGGGATTTTGC
GTCGAGAGTGCCGGACCTTCCGTCCGCATTTGCCGAACTCCAGAAGCACCTCGACGGAATGCGCCAGCAAGTTTCGAGTG
CGCTCGCCAATGTCTCCGAAACATCGACGGCTGTCGGGGTCGGTGCGAAGGAGATCAGGCAGGCGTCGGATGACCTTGCG
CGCAGGACCGAACAGCAGGCAGCCAGTCTTGAGGAGGCCTCGGCTGCGATGACGACGCTGGCCTCTACGGTGCGTAGCGC
AGCCGACGATGCCGCCCACATGCACGATTCCGTCCAGAAGGCGCATGGCGAGGCCGTCAAGGGCGGATCGGTGGTGGGAG
AGGCCGTCTCTGCCATGAACGACATTCACGATTCCGCGCAGGAAATCGGCAAGATCATCTCGGTGATCGACGGAATTGCC
TTCCAGACAAACCTTCTGGCGCTGAACGCAGGCGTCGAGGCTGCTCGTGCTGGCGACGCGGGGCGCGGCTTTGCGGTGGT
TGCCACTGAAGTTCGCGCGTTGGCGCAGCGCACGGCCGATGCGGCGAGGGACATCAAGCACCTGATCGGGCAGAGTTCCA
ACCAGGTCGAACGCGGGGTCAACCTTGTCGGCCAGACGGGGGAAACCTTTTCGTTGATCGTCGAGCAGGTCGGGCACGTG
GCCGAGCTTGCCAGCAGCATTGCCCGCATGGCCAACGAGCAGGCGACCAGTATCGGGCAGGTTCGCGAGACCGTGCGCGA
GATGGATACAATGACGCAGCAGAATGCGGCAATGGTGGAAGAGGCAACGGCGGCTGCCCGCAGCCTTGCGGGAGAGGCAA
GCCGCCTATCCTCGCTCGTCTCGCAATTTCGCCTGGAAGGCCAAGGCGGCGGCGCGGGCCAGAGAGGCCTGCGCCGCGCG
GCCTGA

Upstream 100 bases:

>100_bases
CGGTGTGTTCGGCTGTCCTCCGGTAAATCCACTTCGGATATGATTACAGTATATTGAAGCGCGCGGACCCATTGCCTTCT
TCAGTCTAGGAGCACTGAAG

Downstream 100 bases:

>100_bases
GAAGTGCGTCAGATGTCGATGACGATCTTGCCGAAATGCCTGCCGCTCTCCTGATGGCGGAAGGCTCCGGCAAGATCGGC
AAGTGGAAAGTGGCGGTCGA

Product: methyl-accepting chemotaxis sensory transducer

Products: NA

Alternate protein names: Methyl-accepting chemotaxis protein [H]

Number of amino acids: Translated: 481; Mature: 481

Protein sequence:

>481_residues
MDTAHTGQDVARKLAFFNIDHKDFERFPHIAKVLENYAPPALDKLYDQIATTPETASFFGSRQAMRHARDKQIEHWAGMF
SGRADRSYFESAERIGNVHARIGLEPGWYIGGYAMVLEQVINAMFSGIGGILGAKRTARSVGSLVKMALLDMEVALSTYF
RAEEAARVAVIDEVSATLRGMADGDFASRVPDLPSAFAELQKHLDGMRQQVSSALANVSETSTAVGVGAKEIRQASDDLA
RRTEQQAASLEEASAAMTTLASTVRSAADDAAHMHDSVQKAHGEAVKGGSVVGEAVSAMNDIHDSAQEIGKIISVIDGIA
FQTNLLALNAGVEAARAGDAGRGFAVVATEVRALAQRTADAARDIKHLIGQSSNQVERGVNLVGQTGETFSLIVEQVGHV
AELASSIARMANEQATSIGQVRETVREMDTMTQQNAAMVEEATAAARSLAGEASRLSSLVSQFRLEGQGGGAGQRGLRRA
A

Sequences:

>Translated_481_residues
MDTAHTGQDVARKLAFFNIDHKDFERFPHIAKVLENYAPPALDKLYDQIATTPETASFFGSRQAMRHARDKQIEHWAGMF
SGRADRSYFESAERIGNVHARIGLEPGWYIGGYAMVLEQVINAMFSGIGGILGAKRTARSVGSLVKMALLDMEVALSTYF
RAEEAARVAVIDEVSATLRGMADGDFASRVPDLPSAFAELQKHLDGMRQQVSSALANVSETSTAVGVGAKEIRQASDDLA
RRTEQQAASLEEASAAMTTLASTVRSAADDAAHMHDSVQKAHGEAVKGGSVVGEAVSAMNDIHDSAQEIGKIISVIDGIA
FQTNLLALNAGVEAARAGDAGRGFAVVATEVRALAQRTADAARDIKHLIGQSSNQVERGVNLVGQTGETFSLIVEQVGHV
AELASSIARMANEQATSIGQVRETVREMDTMTQQNAAMVEEATAAARSLAGEASRLSSLVSQFRLEGQGGGAGQRGLRRA
A
>Mature_481_residues
MDTAHTGQDVARKLAFFNIDHKDFERFPHIAKVLENYAPPALDKLYDQIATTPETASFFGSRQAMRHARDKQIEHWAGMF
SGRADRSYFESAERIGNVHARIGLEPGWYIGGYAMVLEQVINAMFSGIGGILGAKRTARSVGSLVKMALLDMEVALSTYF
RAEEAARVAVIDEVSATLRGMADGDFASRVPDLPSAFAELQKHLDGMRQQVSSALANVSETSTAVGVGAKEIRQASDDLA
RRTEQQAASLEEASAAMTTLASTVRSAADDAAHMHDSVQKAHGEAVKGGSVVGEAVSAMNDIHDSAQEIGKIISVIDGIA
FQTNLLALNAGVEAARAGDAGRGFAVVATEVRALAQRTADAARDIKHLIGQSSNQVERGVNLVGQTGETFSLIVEQVGHV
AELASSIARMANEQATSIGQVRETVREMDTMTQQNAAMVEEATAAARSLAGEASRLSSLVSQFRLEGQGGGAGQRGLRRA
A

Specific function: Chemotactic-signal transducers respond to changes in the concentration of attractants and repellents in the environment, transduce a signal from the outside to the inside of the cell, and facilitate sensory adaptation through the variation of the level of

COG id: COG0840

COG function: function code NT; Methyl-accepting chemotaxis protein

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein. Note=Localized at the flagellum-bearing pole of the swarmer cell [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI1788195, Length=294, Percent_Identity=46.5986394557823, Blast_Score=208, Evalue=7e-55,
Organism=Escherichia coli, GI1787690, Length=302, Percent_Identity=42.3841059602649, Blast_Score=207, Evalue=1e-54,
Organism=Escherichia coli, GI2367378, Length=326, Percent_Identity=44.7852760736196, Blast_Score=206, Evalue=2e-54,
Organism=Escherichia coli, GI1788194, Length=263, Percent_Identity=47.5285171102662, Blast_Score=201, Evalue=7e-53,
Organism=Escherichia coli, GI1789453, Length=247, Percent_Identity=39.2712550607287, Blast_Score=160, Evalue=2e-40,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR004089
- InterPro:   IPR003660 [H]

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal [H]

EC number: NA

Molecular weight: Translated: 51125; Mature: 51125

Theoretical pI: Translated: 5.77; Mature: 5.77

Prosite motif: PS50885 HAMP ; PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDTAHTGQDVARKLAFFNIDHKDFERFPHIAKVLENYAPPALDKLYDQIATTPETASFFG
CCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCHHHHHH
SRQAMRHARDKQIEHWAGMFSGRADRSYFESAERIGNVHARIGLEPGWYIGGYAMVLEQV
HHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCHHHHCCCCCCCHHHHHHHHHHHH
INAMFSGIGGILGAKRTARSVGSLVKMALLDMEVALSTYFRAEEAARVAVIDEVSATLRG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
MADGDFASRVPDLPSAFAELQKHLDGMRQQVSSALANVSETSTAVGVGAKEIRQASDDLA
CCCCCHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
RRTEQQAASLEEASAAMTTLASTVRSAADDAAHMHDSVQKAHGEAVKGGSVVGEAVSAMN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHH
DIHDSAQEIGKIISVIDGIAFQTNLLALNAGVEAARAGDAGRGFAVVATEVRALAQRTAD
HHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCHHHHCCCCCCCHHHHHHHHHHHHHHHHH
AARDIKHLIGQSSNQVERGVNLVGQTGETFSLIVEQVGHVAELASSIARMANEQATSIGQ
HHHHHHHHHCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VRETVREMDTMTQQNAAMVEEATAAARSLAGEASRLSSLVSQFRLEGQGGGAGQRGLRRA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHCC
A
C
>Mature Secondary Structure
MDTAHTGQDVARKLAFFNIDHKDFERFPHIAKVLENYAPPALDKLYDQIATTPETASFFG
CCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCHHHHHH
SRQAMRHARDKQIEHWAGMFSGRADRSYFESAERIGNVHARIGLEPGWYIGGYAMVLEQV
HHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCHHHHCCCCCCCHHHHHHHHHHHH
INAMFSGIGGILGAKRTARSVGSLVKMALLDMEVALSTYFRAEEAARVAVIDEVSATLRG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
MADGDFASRVPDLPSAFAELQKHLDGMRQQVSSALANVSETSTAVGVGAKEIRQASDDLA
CCCCCHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
RRTEQQAASLEEASAAMTTLASTVRSAADDAAHMHDSVQKAHGEAVKGGSVVGEAVSAMN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHH
DIHDSAQEIGKIISVIDGIAFQTNLLALNAGVEAARAGDAGRGFAVVATEVRALAQRTAD
HHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCHHHHCCCCCCCHHHHHHHHHHHHHHHHH
AARDIKHLIGQSSNQVERGVNLVGQTGETFSLIVEQVGHVAELASSIARMANEQATSIGQ
HHHHHHHHHCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VRETVREMDTMTQQNAAMVEEATAAARSLAGEASRLSSLVSQFRLEGQGGGAGQRGLRRA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHCC
A
C

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1577276; 11259647 [H]