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The map label for this gene is fabD [H]

Identifier: 87199448

GI number: 87199448

Start: 1468791

End: 1469726

Strand: Direct

Name: fabD [H]

Synonym: Saro_1427

Alternate gene names: 87199448

Gene position: 1468791-1469726 (Clockwise)

Preceding gene: 87199447

Following gene: 87199449

Centisome position: 41.24

GC content: 65.71

Gene sequence:

>936_bases
ATGCGAGCATTCGTTTTTCCGGGGCAGGGCAGCCAGAAGGTCGGCATGGGTCTTGAACTCGCCGAAGCCAGCGCGGCAGC
CCGCGAGGTCTTCGAGGAGGTTGACGACGCGCTGGGCCAGAAGTTGTTCCAGATCATGAAGGACGGCCCGGAAGACGCTT
TGACGCTTACCGAAAATGCACAGCCTGCAATCATGGCCAACGCCATCGCGGTGCTTCGTGTGCTCGAGCGGGAGGGCGGC
ATCACCCTGGCCGACAAGGCGGACTTCGTCGCCGGGCACAGCCTTGGCGAATATACCGCGCTTTGTGCGGCAGGGGCATT
CAGCCTTTCCGACACGGCCCGACTTCTGAAGTTGCGCGGGCAGTCCATGCAGGCGGCGGTGCCTGTGGGCGAGGGCGCAA
TGTGCGCGCTTCTTGGCGCGGACATCGAGAAGGCAACGGCGCTGGCCGAGGCCGCCGCCGAAGGCGAAGTCTGCACCGTC
GCCAACGACAACGATCCGACGCAGGTCGTGCTGTCCGGCCACAAGGGCGCGATCGAGCGTGCGGTCGGCCTCGTCAAGGA
GCACGGCATCAAGCGGGGCGTGCTGCTGCCGGTATCGGCACCGTTCCACTGCCCTCTCATGCAGCCCGCAGCCGACGCGA
TGGCAGAGGCGTTCGAGAAGACGCCGCCTGGACCCCTGCGCGTCGCGCTGTTCGCCAATGTCACGGCATCGATCGTGACC
GATCCGGCAGAGGTGCAGCGCCTGCTGGTCGAACAGGTAACGGGCCGCGTGCGCTGGCGCGAAAGCGCGATCGCGATGCG
CGAGGCCGGCGTCGATCAGTTCATCGAACTTGGCGGCAAGGTCCTTGGCCCGATGATCAACCGCACCGTTGCGGACGTCT
CCATCACCAGCGTCGTCGGCATGGCCGACATCGAAGCCATCCTGAAGGAGCTCTGA

Upstream 100 bases:

>100_bases
CCACGACGTTGACAACAGGATCGTGCCCTTCGGACTTGCCTGACAGGCAGGTGCGACATAGGGCGCACGCCGAATATCGG
CGCCAAATTGGGAGTGTCAG

Downstream 100 bases:

>100_bases
GAGCCATGGAAAATCGTCTCTTCGACCTTACCGGCATGACCGCCCTCGTGACGGGCGCGGCCGGCGGCATCGGCTCGTCG
ATCTGCCATGCGCTGGCCCG

Product: [acyl-carrier-protein] S-malonyltransferase

Products: NA

Alternate protein names: MCT [H]

Number of amino acids: Translated: 311; Mature: 311

Protein sequence:

>311_residues
MRAFVFPGQGSQKVGMGLELAEASAAAREVFEEVDDALGQKLFQIMKDGPEDALTLTENAQPAIMANAIAVLRVLEREGG
ITLADKADFVAGHSLGEYTALCAAGAFSLSDTARLLKLRGQSMQAAVPVGEGAMCALLGADIEKATALAEAAAEGEVCTV
ANDNDPTQVVLSGHKGAIERAVGLVKEHGIKRGVLLPVSAPFHCPLMQPAADAMAEAFEKTPPGPLRVALFANVTASIVT
DPAEVQRLLVEQVTGRVRWRESAIAMREAGVDQFIELGGKVLGPMINRTVADVSITSVVGMADIEAILKEL

Sequences:

>Translated_311_residues
MRAFVFPGQGSQKVGMGLELAEASAAAREVFEEVDDALGQKLFQIMKDGPEDALTLTENAQPAIMANAIAVLRVLEREGG
ITLADKADFVAGHSLGEYTALCAAGAFSLSDTARLLKLRGQSMQAAVPVGEGAMCALLGADIEKATALAEAAAEGEVCTV
ANDNDPTQVVLSGHKGAIERAVGLVKEHGIKRGVLLPVSAPFHCPLMQPAADAMAEAFEKTPPGPLRVALFANVTASIVT
DPAEVQRLLVEQVTGRVRWRESAIAMREAGVDQFIELGGKVLGPMINRTVADVSITSVVGMADIEAILKEL
>Mature_311_residues
MRAFVFPGQGSQKVGMGLELAEASAAAREVFEEVDDALGQKLFQIMKDGPEDALTLTENAQPAIMANAIAVLRVLEREGG
ITLADKADFVAGHSLGEYTALCAAGAFSLSDTARLLKLRGQSMQAAVPVGEGAMCALLGADIEKATALAEAAAEGEVCTV
ANDNDPTQVVLSGHKGAIERAVGLVKEHGIKRGVLLPVSAPFHCPLMQPAADAMAEAFEKTPPGPLRVALFANVTASIVT
DPAEVQRLLVEQVTGRVRWRESAIAMREAGVDQFIELGGKVLGPMINRTVADVSITSVVGMADIEAILKEL

Specific function: Fatty acid biosynthesis. [C]

COG id: COG0331

COG function: function code I; (acyl-carrier-protein) S-malonyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fabD family [H]

Homologues:

Organism=Homo sapiens, GI51243059, Length=297, Percent_Identity=29.96632996633, Blast_Score=124, Evalue=1e-28,
Organism=Escherichia coli, GI1787334, Length=289, Percent_Identity=42.2145328719723, Blast_Score=197, Evalue=1e-51,
Organism=Caenorhabditis elegans, GI71984332, Length=266, Percent_Identity=28.9473684210526, Blast_Score=106, Evalue=2e-23,
Organism=Caenorhabditis elegans, GI17550940, Length=302, Percent_Identity=25.8278145695364, Blast_Score=78, Evalue=6e-15,
Organism=Drosophila melanogaster, GI24665753, Length=280, Percent_Identity=33.5714285714286, Blast_Score=119, Evalue=4e-27,

Paralogues:

None

Copy number: 500 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001227
- InterPro:   IPR014043
- InterPro:   IPR016035
- InterPro:   IPR004410
- InterPro:   IPR016036 [H]

Pfam domain/function: PF00698 Acyl_transf_1 [H]

EC number: =2.3.1.39 [H]

Molecular weight: Translated: 32539; Mature: 32539

Theoretical pI: Translated: 4.53; Mature: 4.53

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRAFVFPGQGSQKVGMGLELAEASAAAREVFEEVDDALGQKLFQIMKDGPEDALTLTENA
CCEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCC
QPAIMANAIAVLRVLEREGGITLADKADFVAGHSLGEYTALCAAGAFSLSDTARLLKLRG
CCHHHHHHHHHHHHHHHCCCEEEECCCCHHHCCCCHHHHHHHHHCCCCHHHHHHHHHHCC
QSMQAAVPVGEGAMCALLGADIEKATALAEAAAEGEVCTVANDNDPTQVVLSGHKGAIER
CCCEEECCCCCCCEEHHHHCCHHHHHHHHHHHCCCCEEEEECCCCCCEEEEECCCHHHHH
AVGLVKEHGIKRGVLLPVSAPFHCPLMQPAADAMAEAFEKTPPGPLRVALFANVTASIVT
HHHHHHHCCCCCCEEEECCCCCCCCCCCHHHHHHHHHHHCCCCCCEEEEEECCCHHHHHC
DPAEVQRLLVEQVTGRVRWRESAIAMREAGVDQFIELGGKVLGPMINRTVADVSITSVVG
CHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCHHHHHHHHHHHHHHHHHHHHHH
MADIEAILKEL
HHHHHHHHHHC
>Mature Secondary Structure
MRAFVFPGQGSQKVGMGLELAEASAAAREVFEEVDDALGQKLFQIMKDGPEDALTLTENA
CCEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCC
QPAIMANAIAVLRVLEREGGITLADKADFVAGHSLGEYTALCAAGAFSLSDTARLLKLRG
CCHHHHHHHHHHHHHHHCCCEEEECCCCHHHCCCCHHHHHHHHHCCCCHHHHHHHHHHCC
QSMQAAVPVGEGAMCALLGADIEKATALAEAAAEGEVCTVANDNDPTQVVLSGHKGAIER
CCCEEECCCCCCCEEHHHHCCHHHHHHHHHHHCCCCEEEEECCCCCCEEEEECCCHHHHH
AVGLVKEHGIKRGVLLPVSAPFHCPLMQPAADAMAEAFEKTPPGPLRVALFANVTASIVT
HHHHHHHCCCCCCEEEECCCCCCCCCCCHHHHHHHHHHHCCCCCCEEEEEECCCHHHHHC
DPAEVQRLLVEQVTGRVRWRESAIAMREAGVDQFIELGGKVLGPMINRTVADVSITSVVG
CHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCHHHHHHHHHHHHHHHHHHHHHH
MADIEAILKEL
HHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8759840; 9534248; 9384377 [H]