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The map label for this gene is cycZ [H]

Identifier: 87199408

GI number: 87199408

Start: 1432097

End: 1432825

Strand: Direct

Name: cycZ [H]

Synonym: Saro_1387

Alternate gene names: 87199408

Gene position: 1432097-1432825 (Clockwise)

Preceding gene: 87199407

Following gene: 87199409

Centisome position: 40.21

GC content: 65.98

Gene sequence:

>729_bases
ATGCACGGTTTCGCAAATCCCGCCCGCTTCCTGCGCCTCGCGCGCTGGCTCATGCCGCTTCTGCTGGTCACCGGGCTGCT
GCTGTCGCTCGGCGCAGTACTCTATGGCGTGCTCGTCGTGCCGCCTGACCGGCTGATGGGCGAGACTGTGCGCATCCTGT
TCATTCATGTGCCCGCCGCATGGCTCGGCATGGCTGGCTGGTCGACCATTGCGATCGCCAGTCTCGTCGAACTGGTCTGG
CGCCACCCGCTGGCCGCCATTGCCGGGCGCGCCGCCGCCGTTCCCGGCGCAACCTTCACCGCTATCTGCCTTGCTACCGG
CTCGATCTGGGCCCGGCCCACGTGGGGAACCTGGTGGGTCTGGGATGGCCGCCTGACGAGCTTTCTCGTCCTCCTGTTCC
TCTATTTCGGCTATATCGCGCTTTCCGGCGCGGCACAGCGCGACATGGCATCGGGCGGGGGTGGCAGCCGCATCACCGCG
ATCTTCGGTCTGGTCGGAGCGATCAACATCCCGATCATCAACCGCTCGGTCGTCTGGTGGAACAGTCTGCACCAGCCGCC
CTCGATCACCATGGGCAAGTCTTCGATCGACCCGACGTTTCTCTGGCCGCTGCTGATCGCAGCGCTGGGTTTCAGCCTGG
TGTTCGGCGGCGTCGTACTTGCGCGGATGCGCACTCTCCTGGCCGATATCCAGGCCGAGGCGCGTCTGCGCCGCAAAGCC
ATGGCGTAA

Upstream 100 bases:

>100_bases
CGGCAAGCCATTGCCCTTGCTCCGCAAGGCTGCAGGTGGCAGAGCGCACCTGACCGGCGGCGGGGGTCGCCGGGAGGAAG
GATTCGACTGTCCCGCGGCC

Downstream 100 bases:

>100_bases
AAAGCAGATGCGCGAAGGTCTTCAACAGTGGGATTACGTGGTGGCCGCGCTGGCGATCGGTCTGGTCGGCACGCTGTTGC
TGGTCGGCTGGACGCTCGCG

Product: heme exporter protein CcmC

Products: NA

Alternate protein names: Cytochrome c-type biogenesis protein CycZ [H]

Number of amino acids: Translated: 242; Mature: 242

Protein sequence:

>242_residues
MHGFANPARFLRLARWLMPLLLVTGLLLSLGAVLYGVLVVPPDRLMGETVRILFIHVPAAWLGMAGWSTIAIASLVELVW
RHPLAAIAGRAAAVPGATFTAICLATGSIWARPTWGTWWVWDGRLTSFLVLLFLYFGYIALSGAAQRDMASGGGGSRITA
IFGLVGAINIPIINRSVVWWNSLHQPPSITMGKSSIDPTFLWPLLIAALGFSLVFGGVVLARMRTLLADIQAEARLRRKA
MA

Sequences:

>Translated_242_residues
MHGFANPARFLRLARWLMPLLLVTGLLLSLGAVLYGVLVVPPDRLMGETVRILFIHVPAAWLGMAGWSTIAIASLVELVW
RHPLAAIAGRAAAVPGATFTAICLATGSIWARPTWGTWWVWDGRLTSFLVLLFLYFGYIALSGAAQRDMASGGGGSRITA
IFGLVGAINIPIINRSVVWWNSLHQPPSITMGKSSIDPTFLWPLLIAALGFSLVFGGVVLARMRTLLADIQAEARLRRKA
MA
>Mature_242_residues
MHGFANPARFLRLARWLMPLLLVTGLLLSLGAVLYGVLVVPPDRLMGETVRILFIHVPAAWLGMAGWSTIAIASLVELVW
RHPLAAIAGRAAAVPGATFTAICLATGSIWARPTWGTWWVWDGRLTSFLVLLFLYFGYIALSGAAQRDMASGGGGSRITA
IFGLVGAINIPIINRSVVWWNSLHQPPSITMGKSSIDPTFLWPLLIAALGFSLVFGGVVLARMRTLLADIQAEARLRRKA
MA

Specific function: Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes [H]

COG id: COG0755

COG function: function code O; ABC-type transport system involved in cytochrome c biogenesis, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CcmC/CycZ/HelC family [H]

Homologues:

Organism=Escherichia coli, GI1788527, Length=227, Percent_Identity=41.8502202643172, Blast_Score=161, Evalue=4e-41,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002541
- InterPro:   IPR003557 [H]

Pfam domain/function: PF01578 Cytochrom_C_asm [H]

EC number: NA

Molecular weight: Translated: 26184; Mature: 26184

Theoretical pI: Translated: 12.01; Mature: 12.01

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHGFANPARFLRLARWLMPLLLVTGLLLSLGAVLYGVLVVPPDRLMGETVRILFIHVPAA
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHEEHEEEECCHH
WLGMAGWSTIAIASLVELVWRHPLAAIAGRAAAVPGATFTAICLATGSIWARPTWGTWWV
HHHHCCHHHHHHHHHHHHHHHCHHHHHHCCHHCCCCCHHHHHHHHHCCCEECCCCCEEEE
WDGRLTSFLVLLFLYFGYIALSGAAQRDMASGGGGSRITAIFGLVGAINIPIINRSVVWW
ECCHHHHHHHHHHHHHHHHHHCCHHHHHHCCCCCCHHHHHHHHHHHHHCCCEECCEEEEH
NSLHQPPSITMGKSSIDPTFLWPLLIAALGFSLVFGGVVLARMRTLLADIQAEARLRRKA
HCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
MA
CC
>Mature Secondary Structure
MHGFANPARFLRLARWLMPLLLVTGLLLSLGAVLYGVLVVPPDRLMGETVRILFIHVPAA
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHEEHEEEECCHH
WLGMAGWSTIAIASLVELVWRHPLAAIAGRAAAVPGATFTAICLATGSIWARPTWGTWWV
HHHHCCHHHHHHHHHHHHHHHCHHHHHHCCHHCCCCCHHHHHHHHHCCCEECCCCCEEEE
WDGRLTSFLVLLFLYFGYIALSGAAQRDMASGGGGSRITAIFGLVGAINIPIINRSVVWW
ECCHHHHHHHHHHHHHHHHHHCCHHHHHHCCCCCCHHHHHHHHHHHHHCCCEECCEEEEH
NSLHQPPSITMGKSSIDPTFLWPLLIAALGFSLVFGGVVLARMRTLLADIQAEARLRRKA
HCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
MA
CC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 1850420; 12597275 [H]