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The map label for this gene is trpF [H]

Identifier: 87199325

GI number: 87199325

Start: 1349308

End: 1349997

Strand: Reverse

Name: trpF [H]

Synonym: Saro_1304

Alternate gene names: 87199325

Gene position: 1349997-1349308 (Counterclockwise)

Preceding gene: 87199326

Following gene: 87199323

Centisome position: 37.9

GC content: 71.74

Gene sequence:

>690_bases
ATGAGCGGCGCGTTGCCTCTAACGCGCCGCTCCATGAACGACACGCGCCCCGCATCGGCCATCAAGATCTGCGGCGTCAC
CACGCGTGATGCGCTGGACGCGGCGATCCACGCGCGCGCCACCCACGTCGGGTTCAACTTCTTCCCCCCCTCCCCGCGCT
TCCTGCACCTCGGGCAGGCGCCGGCGCTTGCCGCGCAGGCCGAAGGACACCTCGTTCGCGTCGGGGTTTTCGTCGATGCC
GCCGACGATGCCATTGCCGATGCCGTCGCCGCCGCCCGGCTCGACGCGATCCAGCTTCACGGCAAGGAAGACCCGGCCCG
CGCCGCCCAGCTTCGCGCCCGCTTCGGCAAGCCGGTGTGGAAGGTCATGTCCGTCGCCGGCCCCGACGACATCGCCAGGG
CGGACCTGTACGCCGGCACGGCCGATTTCATCCTGTTCGATGCCAAGACGCCCAAGGGCGCGGCGCTTCCGGGCGGGCTC
GGCCTCGCCTTCGACTGGAACCTGCTGCGCGCCTATCGCGGCCCGCTGCCGTGGGGTCTTGCCGGGGGCCTCTCGCCCGC
CAACGTGGCCGAGGCCGTGCGCGGCACCGGGGCATCGCTGGTCGACGTCTCGTCCGGCGTCGAAAGTGCGCCCGGAGTGA
AGGACGCCGAACTCATCCGCGCCTTCTGCCTGAACGCCCGCGGCGCCTGA

Upstream 100 bases:

>100_bases
GTCCGCTCCCAAGGCCCCCTCGCCGGTCGCCGCTGGCGAACTCGAAATGACGGTGACGGTGAACGTCTCCTACGAACTGG
CCCCCTGAGGCCAAATTGAC

Downstream 100 bases:

>100_bases
CGCCGGGCAGCGGCAGCATCCTGAACGAAAACGGGCGGCCTCCCGAAGGAGACCGCCCGCATCCTGTTCGCTTTCACGGG
GCCTTGCGACCCCGTGCGCC

Product: phosphoribosylanthranilate isomerase

Products: NA

Alternate protein names: PRAI [H]

Number of amino acids: Translated: 229; Mature: 228

Protein sequence:

>229_residues
MSGALPLTRRSMNDTRPASAIKICGVTTRDALDAAIHARATHVGFNFFPPSPRFLHLGQAPALAAQAEGHLVRVGVFVDA
ADDAIADAVAAARLDAIQLHGKEDPARAAQLRARFGKPVWKVMSVAGPDDIARADLYAGTADFILFDAKTPKGAALPGGL
GLAFDWNLLRAYRGPLPWGLAGGLSPANVAEAVRGTGASLVDVSSGVESAPGVKDAELIRAFCLNARGA

Sequences:

>Translated_229_residues
MSGALPLTRRSMNDTRPASAIKICGVTTRDALDAAIHARATHVGFNFFPPSPRFLHLGQAPALAAQAEGHLVRVGVFVDA
ADDAIADAVAAARLDAIQLHGKEDPARAAQLRARFGKPVWKVMSVAGPDDIARADLYAGTADFILFDAKTPKGAALPGGL
GLAFDWNLLRAYRGPLPWGLAGGLSPANVAEAVRGTGASLVDVSSGVESAPGVKDAELIRAFCLNARGA
>Mature_228_residues
SGALPLTRRSMNDTRPASAIKICGVTTRDALDAAIHARATHVGFNFFPPSPRFLHLGQAPALAAQAEGHLVRVGVFVDAA
DDAIADAVAAARLDAIQLHGKEDPARAAQLRARFGKPVWKVMSVAGPDDIARADLYAGTADFILFDAKTPKGAALPGGLG
LAFDWNLLRAYRGPLPWGLAGGLSPANVAEAVRGTGASLVDVSSGVESAPGVKDAELIRAFCLNARGA

Specific function: Bifunctional Enzyme That Catalyzes Two Sequential Steps Of Tryptophan Biosynthetic Pathway. The First Reaction Is Catalyzed By The Isomerase, Coded By The Trpf Domain; The Second Reaction Is Catalyzed By The Synthase, Coded By The Trpc Domain. [C]

COG id: COG0135

COG function: function code E; Phosphoribosylanthranilate isomerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the trpF family [H]

Homologues:

Organism=Escherichia coli, GI87081863, Length=200, Percent_Identity=34.5, Blast_Score=77, Evalue=1e-15,
Organism=Saccharomyces cerevisiae, GI6320210, Length=221, Percent_Identity=29.4117647058824, Blast_Score=73, Evalue=4e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR001240
- InterPro:   IPR011060 [H]

Pfam domain/function: PF00697 PRAI [H]

EC number: =5.3.1.24 [H]

Molecular weight: Translated: 23710; Mature: 23579

Theoretical pI: Translated: 8.76; Mature: 8.76

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSGALPLTRRSMNDTRPASAIKICGVTTRDALDAAIHARATHVGFNFFPPSPRFLHLGQA
CCCCCCCHHCCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHCCCCCCCCCCCCEEECCCC
PALAAQAEGHLVRVGVFVDAADDAIADAVAAARLDAIQLHGKEDPARAAQLRARFGKPVW
CCHHCCCCCCEEEEEEEEECCHHHHHHHHHHHHHHHEEECCCCCHHHHHHHHHHHCCHHH
KVMSVAGPDDIARADLYAGTADFILFDAKTPKGAALPGGLGLAFDWNLLRAYRGPLPWGL
HHHHHCCCCHHHHHHHCCCCEEEEEEECCCCCCCCCCCCCEEEEHHHHHHHHCCCCCCCC
AGGLSPANVAEAVRGTGASLVDVSSGVESAPGVKDAELIRAFCLNARGA
CCCCCHHHHHHHHHCCCCCEEECCCCCCCCCCCCHHHHHHHHHHCCCCC
>Mature Secondary Structure 
SGALPLTRRSMNDTRPASAIKICGVTTRDALDAAIHARATHVGFNFFPPSPRFLHLGQA
CCCCCCHHCCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHCCCCCCCCCCCCEEECCCC
PALAAQAEGHLVRVGVFVDAADDAIADAVAAARLDAIQLHGKEDPARAAQLRARFGKPVW
CCHHCCCCCCEEEEEEEEECCHHHHHHHHHHHHHHHEEECCCCCHHHHHHHHHHHCCHHH
KVMSVAGPDDIARADLYAGTADFILFDAKTPKGAALPGGLGLAFDWNLLRAYRGPLPWGL
HHHHHCCCCHHHHHHHCCCCEEEEEEECCCCCCCCCCCCCEEEEHHHHHHHHCCCCCCCC
AGGLSPANVAEAVRGTGASLVDVSSGVESAPGVKDAELIRAFCLNARGA
CCCCCHHHHHHHHHCCCCCEEECCCCCCCCCCCCHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA