| Definition | Novosphingobium aromaticivorans DSM 12444 chromosome, complete genome. |
|---|---|
| Accession | NC_007794 |
| Length | 3,561,584 |
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The map label for this gene is ucpA [C]
Identifier: 87198897
GI number: 87198897
Start: 930813
End: 931592
Strand: Reverse
Name: ucpA [C]
Synonym: Saro_0875
Alternate gene names: 87198897
Gene position: 931592-930813 (Counterclockwise)
Preceding gene: 87198898
Following gene: 87198895
Centisome position: 26.16
GC content: 67.05
Gene sequence:
>780_bases ATGGGCAGGGTTCAGGGCAAGAAGGCACTCGTCACCGGGGCGGCGCAAGGCCTCGGCGCGGCACACGCATGGATGCTGGC GCGCGAAGGCGCCAGGGTGCTGCTCACCGACATCAACGGCGAAGGCGCAACGGCAACGGCTGCGGCAATCAACGCCGAAC TGGGGGCAGGCACGGCTTTCGCCATGCGCCATGACGTGACCAGCGCGGACGATTGGGACGCGGCAATCGCGTTCGCCGCC GAGAAGCTCGGCGGGCTTTCGGTCCTGGTCAACAACGCGGGCGTCGGCGTGCGCGGCAATATCGAGACCTGCACGCTGGA AGAATGGCACCGGGGCTTTGCCATCAACGTCGACAGCGTGTTCCTGGGTTGCCAGAAGGCGCTGCCGCTGCTGCGCGACA GCCAGCCCGCCTCGATCGTCAACATCAGCTCGATCGCGGGTCTCATCGCCTCGGACACGATGCCCGGCTACAACGCCAGC AAGGCGGCGGTGTGGATGCTGACCAAGTCGGTCGCGCTGTACTGCGCCAAGCGCGGCTGGGACATCCGCTGCAACTCGGT CCACCCGACGTTCGTCGACACCCCGATCCTCGACGGCATCAGCGCGAACGCCAATCTGGAAAAGTCGGTGGTCATGGGCA AGCTCGCCCGCCAGATCCCGCTGGGCCGCGTGGGCGAACCCGACGACATTGCGGCGGGCGTGCTCTACCTCGCCAGCGAC GAAAGCCGCTTCATGACCGGCGCGGAGCTGAAGCTGGATGGCGGCATCTCGGCGATGTGA
Upstream 100 bases:
>100_bases TGCTTCTCGCCCCCGGCATCATGGGCTGACACTTCCGCCGCTTGCGTGATGGCTCCTAACTTGCTTCGTTGACGCAAACG GAAAGCAGGAGAGGCAGAAG
Downstream 100 bases:
>100_bases TCCCGGGCACATCGCGGGTGGCCGTTCGGGCGCGATGCAGAAACCGCTGTCCTACACGCCCCCAAGATGCCAGCGTCCCC GTTCGCTCCTTGAACCGCGA
Product: short chain dehydrogenase
Products: NA
Alternate protein names: NA
Number of amino acids: Translated: 259; Mature: 258
Protein sequence:
>259_residues MGRVQGKKALVTGAAQGLGAAHAWMLAREGARVLLTDINGEGATATAAAINAELGAGTAFAMRHDVTSADDWDAAIAFAA EKLGGLSVLVNNAGVGVRGNIETCTLEEWHRGFAINVDSVFLGCQKALPLLRDSQPASIVNISSIAGLIASDTMPGYNAS KAAVWMLTKSVALYCAKRGWDIRCNSVHPTFVDTPILDGISANANLEKSVVMGKLARQIPLGRVGEPDDIAAGVLYLASD ESRFMTGAELKLDGGISAM
Sequences:
>Translated_259_residues MGRVQGKKALVTGAAQGLGAAHAWMLAREGARVLLTDINGEGATATAAAINAELGAGTAFAMRHDVTSADDWDAAIAFAA EKLGGLSVLVNNAGVGVRGNIETCTLEEWHRGFAINVDSVFLGCQKALPLLRDSQPASIVNISSIAGLIASDTMPGYNAS KAAVWMLTKSVALYCAKRGWDIRCNSVHPTFVDTPILDGISANANLEKSVVMGKLARQIPLGRVGEPDDIAAGVLYLASD ESRFMTGAELKLDGGISAM >Mature_258_residues GRVQGKKALVTGAAQGLGAAHAWMLAREGARVLLTDINGEGATATAAAINAELGAGTAFAMRHDVTSADDWDAAIAFAAE KLGGLSVLVNNAGVGVRGNIETCTLEEWHRGFAINVDSVFLGCQKALPLLRDSQPASIVNISSIAGLIASDTMPGYNASK AAVWMLTKSVALYCAKRGWDIRCNSVHPTFVDTPILDGISANANLEKSVVMGKLARQIPLGRVGEPDDIAAGVLYLASDE SRFMTGAELKLDGGISAM
Specific function: Unknown
COG id: COG1028
COG function: function code IQR; Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Unknown [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]
Homologues:
Organism=Homo sapiens, GI66933014, Length=258, Percent_Identity=37.2093023255814, Blast_Score=107, Evalue=8e-24, Organism=Homo sapiens, GI15277342, Length=264, Percent_Identity=32.5757575757576, Blast_Score=105, Evalue=3e-23, Organism=Homo sapiens, GI31542939, Length=254, Percent_Identity=31.496062992126, Blast_Score=105, Evalue=5e-23, Organism=Homo sapiens, GI32483357, Length=250, Percent_Identity=31.2, Blast_Score=100, Evalue=1e-21, Organism=Homo sapiens, GI40254992, Length=247, Percent_Identity=31.9838056680162, Blast_Score=100, Evalue=1e-21, Organism=Homo sapiens, GI59889578, Length=228, Percent_Identity=32.4561403508772, Blast_Score=91, Evalue=8e-19, Organism=Homo sapiens, GI5031737, Length=254, Percent_Identity=30.7086614173228, Blast_Score=90, Evalue=2e-18, Organism=Homo sapiens, GI4758504, Length=266, Percent_Identity=31.9548872180451, Blast_Score=88, Evalue=7e-18, Organism=Homo sapiens, GI7705925, Length=252, Percent_Identity=29.7619047619048, Blast_Score=85, Evalue=8e-17, Organism=Homo sapiens, GI224922801, Length=173, Percent_Identity=34.1040462427746, Blast_Score=81, Evalue=1e-15, Organism=Homo sapiens, GI83715985, Length=266, Percent_Identity=30.8270676691729, Blast_Score=78, Evalue=7e-15, Organism=Homo sapiens, GI19923817, Length=260, Percent_Identity=26.9230769230769, Blast_Score=77, Evalue=1e-14, Organism=Homo sapiens, GI33667109, Length=194, Percent_Identity=32.9896907216495, Blast_Score=75, Evalue=8e-14, Organism=Homo sapiens, GI126723750, Length=254, Percent_Identity=27.5590551181102, Blast_Score=73, Evalue=2e-13, Organism=Homo sapiens, GI40807363, Length=199, Percent_Identity=29.1457286432161, Blast_Score=72, Evalue=7e-13, Organism=Homo sapiens, GI32455239, Length=164, Percent_Identity=32.9268292682927, Blast_Score=72, Evalue=7e-13, Organism=Homo sapiens, GI5031765, Length=164, Percent_Identity=32.9268292682927, Blast_Score=72, Evalue=7e-13, Organism=Homo sapiens, GI126723191, Length=183, Percent_Identity=31.6939890710383, Blast_Score=71, Evalue=8e-13, Organism=Homo sapiens, GI310128830, Length=229, Percent_Identity=26.2008733624454, Blast_Score=69, Evalue=4e-12, Organism=Homo sapiens, GI310115468, Length=229, Percent_Identity=26.2008733624454, Blast_Score=69, Evalue=4e-12, Organism=Homo sapiens, GI142976729, Length=219, Percent_Identity=27.8538812785388, Blast_Score=69, Evalue=6e-12, Organism=Escherichia coli, GI87082100, Length=261, Percent_Identity=36.0153256704981, Blast_Score=124, Evalue=5e-30, Organism=Escherichia coli, GI1790717, Length=251, Percent_Identity=30.6772908366534, Blast_Score=119, Evalue=3e-28, Organism=Escherichia coli, GI1787335, Length=252, Percent_Identity=32.9365079365079, Blast_Score=107, Evalue=1e-24, Organism=Escherichia coli, GI1787905, Length=253, Percent_Identity=32.8063241106719, Blast_Score=102, Evalue=2e-23, Organism=Escherichia coli, GI1789378, Length=246, Percent_Identity=33.3333333333333, Blast_Score=100, Evalue=7e-23, Organism=Escherichia coli, GI2367175, Length=255, Percent_Identity=30.9803921568627, Blast_Score=97, Evalue=1e-21, Organism=Escherichia coli, GI1786812, Length=257, Percent_Identity=31.1284046692607, Blast_Score=94, Evalue=9e-21, Organism=Escherichia coli, GI87082160, Length=256, Percent_Identity=28.515625, Blast_Score=92, Evalue=4e-20, Organism=Escherichia coli, GI1788459, Length=252, Percent_Identity=29.3650793650794, Blast_Score=88, Evalue=5e-19, Organism=Escherichia coli, GI1789208, Length=254, Percent_Identity=28.3464566929134, Blast_Score=87, Evalue=1e-18, Organism=Escherichia coli, GI1789057, Length=254, Percent_Identity=28.740157480315, Blast_Score=86, Evalue=2e-18, Organism=Escherichia coli, GI2367365, Length=263, Percent_Identity=30.4182509505703, Blast_Score=81, Evalue=6e-17, Organism=Caenorhabditis elegans, GI25147288, Length=254, Percent_Identity=35.4330708661417, Blast_Score=129, Evalue=2e-30, Organism=Caenorhabditis elegans, GI17538486, Length=267, Percent_Identity=34.0823970037453, Blast_Score=120, Evalue=5e-28, Organism=Caenorhabditis elegans, GI17555706, Length=254, Percent_Identity=33.4645669291339, Blast_Score=113, Evalue=1e-25, Organism=Caenorhabditis elegans, GI17560332, Length=272, Percent_Identity=34.9264705882353, Blast_Score=112, Evalue=1e-25, Organism=Caenorhabditis elegans, GI17563726, Length=265, Percent_Identity=33.2075471698113, Blast_Score=111, Evalue=4e-25, Organism=Caenorhabditis elegans, GI17538480, Length=266, Percent_Identity=32.3308270676692, Blast_Score=110, Evalue=7e-25, Organism=Caenorhabditis elegans, GI17559104, Length=269, Percent_Identity=33.0855018587361, Blast_Score=109, Evalue=2e-24, Organism=Caenorhabditis elegans, GI72000259, Length=268, Percent_Identity=32.8358208955224, Blast_Score=104, Evalue=6e-23, Organism=Caenorhabditis elegans, GI17551412, Length=270, Percent_Identity=32.5925925925926, Blast_Score=103, Evalue=1e-22, Organism=Caenorhabditis elegans, GI17565030, Length=265, Percent_Identity=32.4528301886792, Blast_Score=102, Evalue=1e-22, Organism=Caenorhabditis elegans, GI17562904, Length=266, Percent_Identity=31.9548872180451, Blast_Score=102, Evalue=2e-22, Organism=Caenorhabditis elegans, GI17560150, Length=262, Percent_Identity=32.4427480916031, Blast_Score=100, Evalue=9e-22, Organism=Caenorhabditis elegans, GI17560676, Length=251, Percent_Identity=29.8804780876494, Blast_Score=99, Evalue=2e-21, Organism=Caenorhabditis elegans, GI17562906, Length=269, Percent_Identity=32.7137546468402, Blast_Score=99, Evalue=2e-21, Organism=Caenorhabditis elegans, GI17562990, Length=262, Percent_Identity=31.2977099236641, Blast_Score=99, Evalue=2e-21, Organism=Caenorhabditis elegans, GI193204405, Length=269, Percent_Identity=33.0855018587361, Blast_Score=98, Evalue=3e-21, Organism=Caenorhabditis elegans, GI17561402, Length=258, Percent_Identity=28.6821705426357, Blast_Score=98, Evalue=5e-21, Organism=Caenorhabditis elegans, GI17531453, Length=266, Percent_Identity=31.203007518797, Blast_Score=93, Evalue=1e-19, Organism=Caenorhabditis elegans, GI17508651, Length=258, Percent_Identity=34.4961240310078, Blast_Score=92, Evalue=2e-19, Organism=Caenorhabditis elegans, GI115534694, Length=252, Percent_Identity=32.9365079365079, Blast_Score=92, Evalue=4e-19, Organism=Caenorhabditis elegans, GI17544670, Length=271, Percent_Identity=30.6273062730627, Blast_Score=91, Evalue=5e-19, Organism=Caenorhabditis elegans, GI17562910, Length=266, Percent_Identity=29.6992481203008, Blast_Score=91, Evalue=5e-19, Organism=Caenorhabditis elegans, GI17562908, Length=266, Percent_Identity=31.203007518797, Blast_Score=90, Evalue=1e-18, Organism=Caenorhabditis elegans, GI71994600, Length=254, Percent_Identity=30.3149606299213, Blast_Score=90, Evalue=1e-18, Organism=Caenorhabditis elegans, GI17560220, Length=271, Percent_Identity=31.3653136531365, Blast_Score=89, Evalue=2e-18, Organism=Caenorhabditis elegans, GI71994604, Length=256, Percent_Identity=30.078125, Blast_Score=88, Evalue=4e-18, Organism=Caenorhabditis elegans, GI17564282, Length=202, Percent_Identity=27.2277227722772, Blast_Score=87, Evalue=8e-18, Organism=Caenorhabditis elegans, GI193203117, Length=203, Percent_Identity=28.0788177339901, Blast_Score=85, Evalue=3e-17, Organism=Caenorhabditis elegans, GI193203115, Length=202, Percent_Identity=28.2178217821782, Blast_Score=84, Evalue=6e-17, Organism=Caenorhabditis elegans, GI17538182, Length=265, Percent_Identity=29.0566037735849, Blast_Score=75, Evalue=3e-14, Organism=Caenorhabditis elegans, GI17568967, Length=244, Percent_Identity=27.4590163934426, Blast_Score=74, Evalue=6e-14, Organism=Caenorhabditis elegans, GI17508895, Length=201, Percent_Identity=30.3482587064677, Blast_Score=70, Evalue=1e-12, Organism=Caenorhabditis elegans, GI17536025, Length=265, Percent_Identity=29.811320754717, Blast_Score=64, Evalue=8e-11, Organism=Saccharomyces cerevisiae, GI6322861, Length=243, Percent_Identity=26.7489711934156, Blast_Score=65, Evalue=8e-12, Organism=Drosophila melanogaster, GI21357041, Length=264, Percent_Identity=35.6060606060606, Blast_Score=122, Evalue=3e-28, Organism=Drosophila melanogaster, GI28571526, Length=264, Percent_Identity=35.2272727272727, Blast_Score=120, Evalue=1e-27, Organism=Drosophila melanogaster, GI23397609, Length=252, Percent_Identity=38.0952380952381, Blast_Score=119, Evalue=3e-27, Organism=Drosophila melanogaster, GI24639444, Length=260, Percent_Identity=31.5384615384615, Blast_Score=115, Evalue=3e-26, Organism=Drosophila melanogaster, GI24644339, Length=259, Percent_Identity=33.976833976834, Blast_Score=112, Evalue=2e-25, Organism=Drosophila melanogaster, GI21355319, Length=262, Percent_Identity=31.2977099236641, Blast_Score=112, Evalue=3e-25, Organism=Drosophila melanogaster, GI24643142, Length=252, Percent_Identity=36.1111111111111, Blast_Score=100, Evalue=7e-22, Organism=Drosophila melanogaster, GI24644337, Length=260, Percent_Identity=34.2307692307692, Blast_Score=90, Evalue=2e-18, Organism=Drosophila melanogaster, GI17737361, Length=266, Percent_Identity=32.7067669172932, Blast_Score=88, Evalue=5e-18, Organism=Drosophila melanogaster, GI281364892, Length=216, Percent_Identity=29.6296296296296, Blast_Score=78, Evalue=6e-15, Organism=Drosophila melanogaster, GI24649181, Length=193, Percent_Identity=31.6062176165803, Blast_Score=77, Evalue=1e-14, Organism=Drosophila melanogaster, GI18859837, Length=195, Percent_Identity=29.2307692307692, Blast_Score=74, Evalue=1e-13, Organism=Drosophila melanogaster, GI24640492, Length=193, Percent_Identity=29.0155440414508, Blast_Score=69, Evalue=3e-12, Organism=Drosophila melanogaster, GI21355631, Length=164, Percent_Identity=28.0487804878049, Blast_Score=68, Evalue=6e-12,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR002198 - InterPro: IPR002347 - InterPro: IPR016040 - InterPro: IPR020904 [H]
Pfam domain/function: PF00106 adh_short [H]
EC number: =1.1.1.51 [H]
Molecular weight: Translated: 26911; Mature: 26780
Theoretical pI: Translated: 5.68; Mature: 5.68
Prosite motif: PS00061 ADH_SHORT
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
1.5 %Cys (Translated Protein) 3.1 %Met (Translated Protein) 4.6 %Cys+Met (Translated Protein) 1.6 %Cys (Mature Protein) 2.7 %Met (Mature Protein) 4.3 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MGRVQGKKALVTGAAQGLGAAHAWMLAREGARVLLTDINGEGATATAAAINAELGAGTAF CCCCCCCCEEEECCHHCCCHHHHHHHHHCCCEEEEEECCCCCCEEEHEEEECCCCCCEEE AMRHDVTSADDWDAAIAFAAEKLGGLSVLVNNAGVGVRGNIETCTLEEWHRGFAINVDSV EEECCCCCCCCHHHHHHHHHHHCCCEEEEEECCCCCEECCCCEEEHHHHHCCEEEEHHHH FLGCQKALPLLRDSQPASIVNISSIAGLIASDTMPGYNASKAAVWMLTKSVALYCAKRGW HHHHHHHHHHHCCCCCCCEEEHHHHHHHHHCCCCCCCCCCCCEEEHHHHHHHHHHHHCCC DIRCNSVHPTFVDTPILDGISANANLEKSVVMGKLARQIPLGRVGEPDDIAAGVLYLASD CEEECCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEEECC ESRFMTGAELKLDGGISAM CCCEEECCEEEECCCCCCC >Mature Secondary Structure GRVQGKKALVTGAAQGLGAAHAWMLAREGARVLLTDINGEGATATAAAINAELGAGTAF CCCCCCCEEEECCHHCCCHHHHHHHHHCCCEEEEEECCCCCCEEEHEEEECCCCCCEEE AMRHDVTSADDWDAAIAFAAEKLGGLSVLVNNAGVGVRGNIETCTLEEWHRGFAINVDSV EEECCCCCCCCHHHHHHHHHHHCCCEEEEEECCCCCEECCCCEEEHHHHHCCEEEEHHHH FLGCQKALPLLRDSQPASIVNISSIAGLIASDTMPGYNASKAAVWMLTKSVALYCAKRGW HHHHHHHHHHHCCCCCCCEEEHHHHHHHHHCCCCCCCCCCCCEEEHHHHHHHHHHHHCCC DIRCNSVHPTFVDTPILDGISANANLEKSVVMGKLARQIPLGRVGEPDDIAAGVLYLASD CEEECCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEEECC ESRFMTGAELKLDGGISAM CCCEEECCEEEECCCCCCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 10.0
TargetDB status: NA
Availability: NA
References: 8382516; 2026158; 8617258 [H]