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The map label for this gene is yafC [C]

Identifier: 87198895

GI number: 87198895

Start: 928492

End: 929379

Strand: Reverse

Name: yafC [C]

Synonym: Saro_0873

Alternate gene names: 87198895

Gene position: 929379-928492 (Counterclockwise)

Preceding gene: 87198897

Following gene: 87198894

Centisome position: 26.09

GC content: 69.48

Gene sequence:

>888_bases
ATGAGCAATCGCTGGGACGGGATAGACGAGGTCGTGGCAGTGGCCGATACCGGCACTTTCGTGGCCGGGGCCAAACGGCT
CGGAACCTCCACATCGCACGTCAGCCGGGCGGTCGCGCGGCTCGAACAGAGCCTCGGCGCGCAGTTGTTCCACCGCACCA
CCCGCGCCGTCAGCATGACCGATACCGGGCGCATGCTGGTCGACCAGTTCCGCCGCCTGATCGCAGAGCGCGACGAGGCC
ATCGCGATGCTCGATCTCCAGGGCGAGCCGCAGGGGCAGCTTCGCATCACCTGCCCCACCGCGCTGGGCGAGCGGTTCGT
CGCGCCCATCGTGCGGGCCTATGTGCAGGAATATCCCAAGCTCTCGGTCGACCTCGACATGTCGAACCGCGTGGTCGAAC
TGGTCTCCGAAGGCTACGACCTTGCCATCCGCACCGGCACCCTGCCCGACAGCCGCCTGATCCGCACGCAGATCGCGACG
CGCGGCATCGTCACCTGCGCCGCGCCTTCCTATCTGGAAGAGCGCGGGACGCCGCAGACGGTGGACGACCTGCTTGGCCA
CGAGTGCATCCCCGCGACGTCCGACGTGTGGCGCTACCGCGTGGACGGCGAGCAGCGGACCATCCGGCCCCGGGGACGCT
GGCGTTGCAGCAACGGCGCGGCGGTGTTCGACGCGGCGGTGGCCGGCATGGGCCTGTGCCAGCTGCCCGCCTTCTACGTG
AACAGGGCCATCGCCGCCGGTCAGCTCGTCCCGGTGCTGGACGAGTTCCGGCCCGAGGACGACCCGATCTGGGCAGTCTA
CCCGCAGCGCCGCCATCTCCTCCCCAAGGTGCAGCGGCTGATCGAGAAGCTGCGCCGCGAGTTGCCGACCGCGCTTCTGG
CAGGCTGA

Upstream 100 bases:

>100_bases
ATTTCGTGCGGTCTCCCTTTGACGTGGCGGTCCGATAGCATAATTGCTACAGCCCTGTTAAATTGCGCAATACGCGAAAC
ACTGTTGCAAGACGAGAATA

Downstream 100 bases:

>100_bases
ACCGCTCCGGACGAAATACCTATGCACGCGGCATGACATCGCTGACACGGACAGCTAGACCCTGTCGCGCAATGGCCCGT
CGAGTGGCCGGTTGAGGAGA

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: ORF2 [H]

Number of amino acids: Translated: 295; Mature: 294

Protein sequence:

>295_residues
MSNRWDGIDEVVAVADTGTFVAGAKRLGTSTSHVSRAVARLEQSLGAQLFHRTTRAVSMTDTGRMLVDQFRRLIAERDEA
IAMLDLQGEPQGQLRITCPTALGERFVAPIVRAYVQEYPKLSVDLDMSNRVVELVSEGYDLAIRTGTLPDSRLIRTQIAT
RGIVTCAAPSYLEERGTPQTVDDLLGHECIPATSDVWRYRVDGEQRTIRPRGRWRCSNGAAVFDAAVAGMGLCQLPAFYV
NRAIAAGQLVPVLDEFRPEDDPIWAVYPQRRHLLPKVQRLIEKLRRELPTALLAG

Sequences:

>Translated_295_residues
MSNRWDGIDEVVAVADTGTFVAGAKRLGTSTSHVSRAVARLEQSLGAQLFHRTTRAVSMTDTGRMLVDQFRRLIAERDEA
IAMLDLQGEPQGQLRITCPTALGERFVAPIVRAYVQEYPKLSVDLDMSNRVVELVSEGYDLAIRTGTLPDSRLIRTQIAT
RGIVTCAAPSYLEERGTPQTVDDLLGHECIPATSDVWRYRVDGEQRTIRPRGRWRCSNGAAVFDAAVAGMGLCQLPAFYV
NRAIAAGQLVPVLDEFRPEDDPIWAVYPQRRHLLPKVQRLIEKLRRELPTALLAG
>Mature_294_residues
SNRWDGIDEVVAVADTGTFVAGAKRLGTSTSHVSRAVARLEQSLGAQLFHRTTRAVSMTDTGRMLVDQFRRLIAERDEAI
AMLDLQGEPQGQLRITCPTALGERFVAPIVRAYVQEYPKLSVDLDMSNRVVELVSEGYDLAIRTGTLPDSRLIRTQIATR
GIVTCAAPSYLEERGTPQTVDDLLGHECIPATSDVWRYRVDGEQRTIRPRGRWRCSNGAAVFDAAVAGMGLCQLPAFYVN
RAIAAGQLVPVLDEFRPEDDPIWAVYPQRRHLLPKVQRLIEKLRRELPTALLAG

Specific function: Unknown

COG id: COG0583

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1786401, Length=287, Percent_Identity=30.3135888501742, Blast_Score=142, Evalue=3e-35,
Organism=Escherichia coli, GI1789639, Length=281, Percent_Identity=30.2491103202847, Blast_Score=139, Evalue=2e-34,
Organism=Escherichia coli, GI1787589, Length=282, Percent_Identity=30.8510638297872, Blast_Score=138, Evalue=4e-34,
Organism=Escherichia coli, GI87081978, Length=280, Percent_Identity=33.5714285714286, Blast_Score=134, Evalue=5e-33,
Organism=Escherichia coli, GI145693193, Length=289, Percent_Identity=27.681660899654, Blast_Score=130, Evalue=8e-32,
Organism=Escherichia coli, GI1789440, Length=283, Percent_Identity=27.208480565371, Blast_Score=126, Evalue=2e-30,
Organism=Escherichia coli, GI1787128, Length=271, Percent_Identity=28.0442804428044, Blast_Score=108, Evalue=3e-25,
Organism=Escherichia coli, GI1786448, Length=267, Percent_Identity=25.0936329588015, Blast_Score=83, Evalue=2e-17,
Organism=Escherichia coli, GI1790011, Length=294, Percent_Identity=23.469387755102, Blast_Score=79, Evalue=4e-16,
Organism=Escherichia coli, GI1788706, Length=167, Percent_Identity=26.9461077844311, Blast_Score=66, Evalue=2e-12,
Organism=Escherichia coli, GI1788481, Length=286, Percent_Identity=24.1258741258741, Blast_Score=65, Evalue=7e-12,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 32752; Mature: 32621

Theoretical pI: Translated: 7.88; Mature: 7.88

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNRWDGIDEVVAVADTGTFVAGAKRLGTSTSHVSRAVARLEQSLGAQLFHRTTRAVSMT
CCCCCCCHHHHHHHHCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHEEEEC
DTGRMLVDQFRRLIAERDEAIAMLDLQGEPQGQLRITCPTALGERFVAPIVRAYVQEYPK
CCHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCEEEECCHHHHHHHHHHHHHHHHHHCCC
LSVDLDMSNRVVELVSEGYDLAIRTGTLPDSRLIRTQIATRGIVTCAAPSYLEERGTPQT
EEEEECCHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHCCEEEECCCHHHHHCCCCCH
VDDLLGHECIPATSDVWRYRVDGEQRTIRPRGRWRCSNGAAVFDAAVAGMGLCQLPAFYV
HHHHHCCCCCCCCHHHEEEEECCCCCEECCCCCEEECCCCHHHHHHHHCCCHHHHHHHHH
NRAIAAGQLVPVLDEFRPEDDPIWAVYPQRRHLLPKVQRLIEKLRRELPTALLAG
HHHHHCCCHHHHHHHCCCCCCCEEEECCHHHHHHHHHHHHHHHHHHHCCHHHHCC
>Mature Secondary Structure 
SNRWDGIDEVVAVADTGTFVAGAKRLGTSTSHVSRAVARLEQSLGAQLFHRTTRAVSMT
CCCCCCHHHHHHHHCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHEEEEC
DTGRMLVDQFRRLIAERDEAIAMLDLQGEPQGQLRITCPTALGERFVAPIVRAYVQEYPK
CCHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCEEEECCHHHHHHHHHHHHHHHHHHCCC
LSVDLDMSNRVVELVSEGYDLAIRTGTLPDSRLIRTQIATRGIVTCAAPSYLEERGTPQT
EEEEECCHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHCCEEEECCCHHHHHCCCCCH
VDDLLGHECIPATSDVWRYRVDGEQRTIRPRGRWRCSNGAAVFDAAVAGMGLCQLPAFYV
HHHHHCCCCCCCCHHHEEEEECCCCCEECCCCCEEECCCCHHHHHHHHCCCHHHHHHHHH
NRAIAAGQLVPVLDEFRPEDDPIWAVYPQRRHLLPKVQRLIEKLRRELPTALLAG
HHHHHCCCHHHHHHHCCCCCCCEEEECCHHHHHHHHHHHHHHHHHHHCCHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8635745; 7542800 [H]