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The map label for this gene is cdd [H]

Identifier: 87198171

GI number: 87198171

Start: 146720

End: 147157

Strand: Direct

Name: cdd [H]

Synonym: Saro_0145

Alternate gene names: 87198171

Gene position: 146720-147157 (Clockwise)

Preceding gene: 87198170

Following gene: 87198172

Centisome position: 4.12

GC content: 67.81

Gene sequence:

>438_bases
ATGAGTATCGATCTTGTCGCGGAACGCCGGGAAGCGCTGGTCGCCGCTGCACGCACGGCGATGGGCACTGCCTATGCGCC
CTATTCCGGTTTCCATGTGGGCGCGGCGCTGCTGTTCGAGGACGGCGCGATCGTTACGGGAGCGAACGTCGAGAACGCCA
GCTACGGCCTCTCGCTTTGCGCCGAGACGGTCGCCTGTTCAATCGCGGCCCACGCGGGGCGCCGCGGCGGACTTCTGGCG
GTGGCGGTGTCCGGAGGCGCTGGCGGGCGGGCGGATGCGGCAATCAGCCCTTGCGGACGCTGCCGGCAGGTGTTGAACGA
ACTGGCCGCGCTTGGCGGGACTGACCCGCTGGTGATCTGCACCAGCGCCAAGGAAACCGTGGAAATGCGGCTGTCTGCGC
TCTTGCCCAATGCCTTCGGTCCGGCCAATCTGGCGTGA

Upstream 100 bases:

>100_bases
AGCCCGGCTACGCCGGCAGGCCGTGGGTCATGTGGACAGCGACCAAGCGCCTGCGTCTGCATGGCGCAAGCGGCCCCCTG
CGCTGGGTCGTCGTGCAGCC

Downstream 100 bases:

>100_bases
AGGTTCAGGGGTAGGCATTCCTGCACGACGTTTCTCAGGGAGAGCCAGTTGGCCATTCTTTCCGACAAGTGGATCCGCGA
CAAGGCGCTGAACGAGGGCA

Product: cytidine deaminase

Products: NA

Alternate protein names: CDA; Cytidine aminohydrolase [H]

Number of amino acids: Translated: 145; Mature: 144

Protein sequence:

>145_residues
MSIDLVAERREALVAAARTAMGTAYAPYSGFHVGAALLFEDGAIVTGANVENASYGLSLCAETVACSIAAHAGRRGGLLA
VAVSGGAGGRADAAISPCGRCRQVLNELAALGGTDPLVICTSAKETVEMRLSALLPNAFGPANLA

Sequences:

>Translated_145_residues
MSIDLVAERREALVAAARTAMGTAYAPYSGFHVGAALLFEDGAIVTGANVENASYGLSLCAETVACSIAAHAGRRGGLLA
VAVSGGAGGRADAAISPCGRCRQVLNELAALGGTDPLVICTSAKETVEMRLSALLPNAFGPANLA
>Mature_144_residues
SIDLVAERREALVAAARTAMGTAYAPYSGFHVGAALLFEDGAIVTGANVENASYGLSLCAETVACSIAAHAGRRGGLLAV
AVSGGAGGRADAAISPCGRCRQVLNELAALGGTDPLVICTSAKETVEMRLSALLPNAFGPANLA

Specific function: This enzyme scavenge exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis [H]

COG id: COG0295

COG function: function code F; Cytidine deaminase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cytidine and deoxycytidylate deaminase family [H]

Homologues:

Organism=Homo sapiens, GI11386157, Length=140, Percent_Identity=39.2857142857143, Blast_Score=95, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI17551074, Length=139, Percent_Identity=40.2877697841727, Blast_Score=90, Evalue=5e-19,
Organism=Caenorhabditis elegans, GI17540514, Length=140, Percent_Identity=41.4285714285714, Blast_Score=83, Evalue=5e-17,
Organism=Saccharomyces cerevisiae, GI6323274, Length=145, Percent_Identity=39.3103448275862, Blast_Score=96, Evalue=3e-21,
Organism=Drosophila melanogaster, GI24582741, Length=145, Percent_Identity=37.2413793103448, Blast_Score=77, Evalue=4e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016192
- InterPro:   IPR002125
- InterPro:   IPR006262
- InterPro:   IPR016193 [H]

Pfam domain/function: PF00383 dCMP_cyt_deam_1 [H]

EC number: =3.5.4.5 [H]

Molecular weight: Translated: 14476; Mature: 14344

Theoretical pI: Translated: 5.68; Mature: 5.68

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.4 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
5.5 %Cys+Met (Translated Protein)
3.5 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSIDLVAERREALVAAARTAMGTAYAPYSGFHVGAALLFEDGAIVTGANVENASYGLSLC
CCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHEEEEEECCCEEECCCCCCCHHHHHHH
AETVACSIAAHAGRRGGLLAVAVSGGAGGRADAAISPCGRCRQVLNELAALGGTDPLVIC
HHHHHHHHHHHCCCCCCEEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCEEEE
TSAKETVEMRLSALLPNAFGPANLA
CCCHHHHHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure 
SIDLVAERREALVAAARTAMGTAYAPYSGFHVGAALLFEDGAIVTGANVENASYGLSLC
CCCHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHEEEEEECCCEEECCCCCCCHHHHHHH
AETVACSIAAHAGRRGGLLAVAVSGGAGGRADAAISPCGRCRQVLNELAALGGTDPLVIC
HHHHHHHHHHHCCCCCCEEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCEEEE
TSAKETVEMRLSALLPNAFGPANLA
CCCHHHHHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11058132 [H]