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The map label for this gene is rnz [H]

Identifier: 86751719

GI number: 86751719

Start: 5222494

End: 5223228

Strand: Direct

Name: rnz [H]

Synonym: RPB_4621

Alternate gene names: 86751719

Gene position: 5222494-5223228 (Clockwise)

Preceding gene: 86751718

Following gene: 86751722

Centisome position: 97.95

GC content: 64.63

Gene sequence:

>735_bases
ATGCAACTGCGATTTGTCGGCTGTGGCGATGCGCTCGGCTCCGGCGGCCGGCTCAACACCTGCTTCCACGTCGCGGGAGA
GCGCGTCAACTTCCTGATCGACTGCGGCGCGACATCGTTGCCCGCGCTGAAGCGCTACGGCATTTCGCGCGATGCGCTCG
ACCTGGTGCTGATCACCCACTTTCACGGCGACCATTTCGGTGGCCTGCCGTTTCTGCTGCTCGATGCGAAATCCGCCAAG
CGCAAGCGACCGCTGGTGATCGCCGGGCCGCCCGGCATCGACATCCGCCTGACGCGGGTGATGGAGGCGCTGTTCGAACA
TTCCTCGGCGACCCAGCCGACGTTCGATCTGCAGGTGATCGCGCTCGACCCGACCGTGCCGCGGACCTTCGGCGCAGTGA
CGGCGACGCCGTTTCCGGTGATCCACGGCGATTCCGGCGGGCCATTCTATGCCTATCGCATCGAAGCCGAAGGCCGCACG
CTGGCCTATAGCGGCGACACGCAATGGACCGATACGCTGGTCGCCGCGGCGCACGACGCCGATCTGTTCATCGCCGAGGC
CTACACCTACGACCGCAATGTGAAGAACCATCTCAGCCTGAAGGCGCTCGAGACCCACCTGCCCGAGATCAATCCGAAGC
GGCTGATCCTCACCCATATGGGCGACGATGTGCTGCACAAGCTCGACACCGTCCCGCATATGGCCGCGAGCGACGGACTG
ATCGTGGAGTTGTAG

Upstream 100 bases:

>100_bases
TCGGGGCGCGTGCAATCCGGCGATGGTTGGGCTTCCGCTCGCCTTCGCCCCAGCGTAGAGGTGCCCTGGCCCGGCAACTG
CCGTGGCCGAGGGATCAGCG

Downstream 100 bases:

>100_bases
TCATTCCGGGGCGCGCCGCAGGCGCGAACCCGGAATCTCGAGATGCTCTGCTCGTATCAGACTCCGGGTTCGCCGCTCCG
CGGCGCCCCGGAATGACGAC

Product: Beta-lactamase-like

Products: NA

Alternate protein names: RNase Z; tRNA 3 endonuclease; tRNase Z [H]

Number of amino acids: Translated: 244; Mature: 244

Protein sequence:

>244_residues
MQLRFVGCGDALGSGGRLNTCFHVAGERVNFLIDCGATSLPALKRYGISRDALDLVLITHFHGDHFGGLPFLLLDAKSAK
RKRPLVIAGPPGIDIRLTRVMEALFEHSSATQPTFDLQVIALDPTVPRTFGAVTATPFPVIHGDSGGPFYAYRIEAEGRT
LAYSGDTQWTDTLVAAAHDADLFIAEAYTYDRNVKNHLSLKALETHLPEINPKRLILTHMGDDVLHKLDTVPHMAASDGL
IVEL

Sequences:

>Translated_244_residues
MQLRFVGCGDALGSGGRLNTCFHVAGERVNFLIDCGATSLPALKRYGISRDALDLVLITHFHGDHFGGLPFLLLDAKSAK
RKRPLVIAGPPGIDIRLTRVMEALFEHSSATQPTFDLQVIALDPTVPRTFGAVTATPFPVIHGDSGGPFYAYRIEAEGRT
LAYSGDTQWTDTLVAAAHDADLFIAEAYTYDRNVKNHLSLKALETHLPEINPKRLILTHMGDDVLHKLDTVPHMAASDGL
IVEL
>Mature_244_residues
MQLRFVGCGDALGSGGRLNTCFHVAGERVNFLIDCGATSLPALKRYGISRDALDLVLITHFHGDHFGGLPFLLLDAKSAK
RKRPLVIAGPPGIDIRLTRVMEALFEHSSATQPTFDLQVIALDPTVPRTFGAVTATPFPVIHGDSGGPFYAYRIEAEGRT
LAYSGDTQWTDTLVAAAHDADLFIAEAYTYDRNVKNHLSLKALETHLPEINPKRLILTHMGDDVLHKLDTVPHMAASDGL
IVEL

Specific function: Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA [H]

COG id: COG1234

COG function: function code R; Metal-dependent hydrolases of the beta-lactamase superfamily III

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RNase Z family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001279
- InterPro:   IPR013471 [H]

Pfam domain/function: PF00753 Lactamase_B [H]

EC number: =3.1.26.11 [H]

Molecular weight: Translated: 26565; Mature: 26565

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQLRFVGCGDALGSGGRLNTCFHVAGERVNFLIDCGATSLPALKRYGISRDALDLVLITH
CEEEEEECCHHCCCCCCEEEEEEECCCEEEEEEECCCCCCCHHHHCCCCCCCEEEEEEEE
FHGDHFGGLPFLLLDAKSAKRKRPLVIAGPPGIDIRLTRVMEALFEHSSATQPTFDLQVI
ECCCCCCCCCEEEEECCCHHCCCCEEEECCCCCCEEHHHHHHHHHHCCCCCCCCEEEEEE
ALDPTVPRTFGAVTATPFPVIHGDSGGPFYAYRIEAEGRTLAYSGDTQWTDTLVAAAHDA
EECCCCCCCCCCEECCCCEEEECCCCCCEEEEEEECCCCEEEECCCCCHHHHEEEEECCC
DLFIAEAYTYDRNVKNHLSLKALETHLPEINPKRLILTHMGDDVLHKLDTVPHMAASDGL
CEEEEEEEECCCCCCHHHHHHHHHHHCCCCCCCEEEEEECCHHHHHHHHCCCCCCCCCCE
IVEL
EEEC
>Mature Secondary Structure
MQLRFVGCGDALGSGGRLNTCFHVAGERVNFLIDCGATSLPALKRYGISRDALDLVLITH
CEEEEEECCHHCCCCCCEEEEEEECCCEEEEEEECCCCCCCHHHHCCCCCCCEEEEEEEE
FHGDHFGGLPFLLLDAKSAKRKRPLVIAGPPGIDIRLTRVMEALFEHSSATQPTFDLQVI
ECCCCCCCCCEEEEECCCHHCCCCEEEECCCCCCEEHHHHHHHHHHCCCCCCCCEEEEEE
ALDPTVPRTFGAVTATPFPVIHGDSGGPFYAYRIEAEGRTLAYSGDTQWTDTLVAAAHDA
EECCCCCCCCCCEECCCCEEEECCCCCCEEEEEEECCCCEEEECCCCCHHHHEEEEECCC
DLFIAEAYTYDRNVKNHLSLKALETHLPEINPKRLILTHMGDDVLHKLDTVPHMAASDGL
CEEEEEEEECCCCCCHHHHHHHHHHHCCCCCCCEEEEEECCHHHHHHHHCCCCCCCCCCE
IVEL
EEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA