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The map label for this gene is atpE [H]

Identifier: 86751670

GI number: 86751670

Start: 5170336

End: 5170563

Strand: Direct

Name: atpE [H]

Synonym: RPB_4572

Alternate gene names: 86751670

Gene position: 5170336-5170563 (Clockwise)

Preceding gene: 86751669

Following gene: 86751671

Centisome position: 96.97

GC content: 62.72

Gene sequence:

>228_bases
ATGGATCCGATTGCCGCGAAGTACATTGGCGCTGGTATTGCCTGCATTGGCATGGGCGGCGCGGGCGCCGGCGTGGGCAT
CATCTTCGGCAACTATCTCGCCGCTGCGGTGCGCAATCCTTCGGCTGCTCAGGGCCAGTTCGGCAACCTGATTTTCGGCT
TCGCGGTGACGGAAGCGCTCGGCATCTTCTCGCTGCTGATCGCGCTGCTGCTGCTGTTCGCCCTCTAA

Upstream 100 bases:

>100_bases
CCATCCTGACTTGCATCTATCTCAACGATGCGATTCACCCGGGCCACTGAGGCCCGGTCTCCGACCTCTCGACAACCAAA
CCCCAACAGGAGTTCGTTAC

Downstream 100 bases:

>100_bases
GAAGTCCAATCCGGTCGTGACGCTGTGGTCGTGACCGGCCGAACAGGAGAAGCCCGTGGCTGAAGGTCATGGCGATGCGA
AGGGCGCAACCGCCCACACG

Product: F0F1 ATP synthase subunit C

Products: ADP; phosphate; H+

Alternate protein names: ATP synthase F(0) sector subunit c; F-type ATPase subunit c; F-ATPase subunit c; Lipid-binding protein [H]

Number of amino acids: Translated: 75; Mature: 75

Protein sequence:

>75_residues
MDPIAAKYIGAGIACIGMGGAGAGVGIIFGNYLAAAVRNPSAAQGQFGNLIFGFAVTEALGIFSLLIALLLLFAL

Sequences:

>Translated_75_residues
MDPIAAKYIGAGIACIGMGGAGAGVGIIFGNYLAAAVRNPSAAQGQFGNLIFGFAVTEALGIFSLLIALLLLFAL
>Mature_75_residues
MDPIAAKYIGAGIACIGMGGAGAGVGIIFGNYLAAAVRNPSAAQGQFGNLIFGFAVTEALGIFSLLIALLLLFAL

Specific function: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits [H]

COG id: COG0636

COG function: function code C; F0F1-type ATP synthase, subunit c/Archaeal/vacuolar-type H+-ATPase, subunit K

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATPase C chain family [H]

Homologues:

Organism=Homo sapiens, GI50593533, Length=71, Percent_Identity=50.7042253521127, Blast_Score=74, Evalue=3e-14,
Organism=Homo sapiens, GI85794840, Length=71, Percent_Identity=50.7042253521127, Blast_Score=74, Evalue=3e-14,
Organism=Homo sapiens, GI50659069, Length=71, Percent_Identity=50.7042253521127, Blast_Score=73, Evalue=6e-14,
Organism=Homo sapiens, GI4885081, Length=71, Percent_Identity=50.7042253521127, Blast_Score=73, Evalue=6e-14,
Organism=Homo sapiens, GI4502301, Length=71, Percent_Identity=50.7042253521127, Blast_Score=72, Evalue=7e-14,
Organism=Homo sapiens, GI50659074, Length=71, Percent_Identity=50.7042253521127, Blast_Score=72, Evalue=7e-14,
Organism=Caenorhabditis elegans, GI71996409, Length=71, Percent_Identity=50.7042253521127, Blast_Score=68, Evalue=8e-13,
Organism=Saccharomyces cerevisiae, GI6226533, Length=70, Percent_Identity=50, Blast_Score=65, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24651601, Length=70, Percent_Identity=52.8571428571429, Blast_Score=73, Evalue=4e-14,
Organism=Drosophila melanogaster, GI24651603, Length=70, Percent_Identity=52.8571428571429, Blast_Score=73, Evalue=4e-14,
Organism=Drosophila melanogaster, GI24651599, Length=70, Percent_Identity=52.8571428571429, Blast_Score=73, Evalue=4e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000454
- InterPro:   IPR002379 [H]

Pfam domain/function: PF00137 ATP-synt_C [H]

EC number: 3.6.3.14

Molecular weight: Translated: 7445; Mature: 7445

Theoretical pI: Translated: 6.23; Mature: 6.23

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDPIAAKYIGAGIACIGMGGAGAGVGIIFGNYLAAAVRNPSAAQGQFGNLIFGFAVTEAL
CCCHHHHHHCCCEEEEECCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHH
GIFSLLIALLLLFAL
HHHHHHHHHHHHHHC
>Mature Secondary Structure
MDPIAAKYIGAGIACIGMGGAGAGVGIIFGNYLAAAVRNPSAAQGQFGNLIFGFAVTEAL
CCCHHHHHHCCCEEEEECCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHH
GIFSLLIALLLLFAL
HHHHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; H2O; H+

Specific reaction: ATP + H2O + H+(in) = ADP + phosphate + H+(out)

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA