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The map label for this gene is ltrA [H]

Identifier: 86751608

GI number: 86751608

Start: 5096552

End: 5097478

Strand: Direct

Name: ltrA [H]

Synonym: RPB_4510

Alternate gene names: 86751608

Gene position: 5096552-5097478 (Clockwise)

Preceding gene: 86751604

Following gene: 86751612

Centisome position: 95.59

GC content: 65.37

Gene sequence:

>927_bases
ATGGATCGTCTCGATTGCCTCAGAGCGTTCGTGAAGACGATGGAAGGCGGCAGTTTCTCCGGCGCCGCCAAAGAGCTCGG
TCTCGGCCAGCCGGCTGTCAGCAAGCGGATCGCATTGCTCGAGAAGGAATTCGGCTCGCAGCTATTCATGCGCAACACCC
GCAAGCTGACGCCGACCCGGGAGGCCCACCGCATCTACGACCTGGCACGGCAGGCGCTGAGCTGTATCGAGATGGCGCGG
GCGAGCATCGCGGAGGCGCCGGCGGTGCCGACCGGGATGTTGCGGCTGGGCGTGCCGTCGTCGTTCGGCCGGCACTACAT
CATGCCGGTGATCGAGCAATATCTGCGCGACTATCCGCAGGTGAAGGTCGACATCCGGTTCAGCGAACAGACCGTCAATC
TGGTCGAGGACGGCATCGAACTGGCGTTGCGGATCGGTGATCTGGAGTCCAGCTCACTCAAGGCGCGGCGGATCGGCCTG
GTGCGGCGTTTCCTGGTGGCGACGCCGGCCTATCTGCGCCGGCAGCCGCAGCCGCAGCTCCCCGGCGATCTGAAGAACCT
GCATTGCATCGCCTACGCGCGGCTGTCGCCGGCCAACCAATGGGCCTTCGACTCCGAGCTGGGGCGCCATGTCGTGCAAA
TCTCCGCCTCCATTATGGTCGACGACGCCGATGCGATGAAGCAGGCGGTGCTGCAGAATCTCGGCGTCGCCATTCTGCCG
GCGTGGAGTGCCGCCGATGCGGTGCGAAGTGGCGAGATGGAGATCGTGCTGCCGGAATTCGCCGTTCCGGCGCTGCCGTT
GAATGCGGTCTATGCCGACACGCAATGGATGTCGCTGCGGGCCCGATGCTTTCTCGACCTGCTGATCGCCCGGTCGCACC
GGTTCAGCGAGGATGTCGACGGCGCCGGGCCGCCCCGCCGCTTTTAA

Upstream 100 bases:

>100_bases
TTGGATGAGTTGTTGTTCTGGTTGATCGCAGCGTAGGAGCGGCCTTGACGGGCGTCTACGGAATGAACAGGATATGATTT
ATTCCACTCAGGAATGATCG

Downstream 100 bases:

>100_bases
TGCAGATGCATCTAATTCTGCATGGCAGCTCCGCCGCCTGCGGCACTTCTACGCACCCCCCGCCGCCCCCATCTCCGAAC
GACCTTCGGAGATGGACGAA

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 308; Mature: 308

Protein sequence:

>308_residues
MDRLDCLRAFVKTMEGGSFSGAAKELGLGQPAVSKRIALLEKEFGSQLFMRNTRKLTPTREAHRIYDLARQALSCIEMAR
ASIAEAPAVPTGMLRLGVPSSFGRHYIMPVIEQYLRDYPQVKVDIRFSEQTVNLVEDGIELALRIGDLESSSLKARRIGL
VRRFLVATPAYLRRQPQPQLPGDLKNLHCIAYARLSPANQWAFDSELGRHVVQISASIMVDDADAMKQAVLQNLGVAILP
AWSAADAVRSGEMEIVLPEFAVPALPLNAVYADTQWMSLRARCFLDLLIARSHRFSEDVDGAGPPRRF

Sequences:

>Translated_308_residues
MDRLDCLRAFVKTMEGGSFSGAAKELGLGQPAVSKRIALLEKEFGSQLFMRNTRKLTPTREAHRIYDLARQALSCIEMAR
ASIAEAPAVPTGMLRLGVPSSFGRHYIMPVIEQYLRDYPQVKVDIRFSEQTVNLVEDGIELALRIGDLESSSLKARRIGL
VRRFLVATPAYLRRQPQPQLPGDLKNLHCIAYARLSPANQWAFDSELGRHVVQISASIMVDDADAMKQAVLQNLGVAILP
AWSAADAVRSGEMEIVLPEFAVPALPLNAVYADTQWMSLRARCFLDLLIARSHRFSEDVDGAGPPRRF
>Mature_308_residues
MDRLDCLRAFVKTMEGGSFSGAAKELGLGQPAVSKRIALLEKEFGSQLFMRNTRKLTPTREAHRIYDLARQALSCIEMAR
ASIAEAPAVPTGMLRLGVPSSFGRHYIMPVIEQYLRDYPQVKVDIRFSEQTVNLVEDGIELALRIGDLESSSLKARRIGL
VRRFLVATPAYLRRQPQPQLPGDLKNLHCIAYARLSPANQWAFDSELGRHVVQISASIMVDDADAMKQAVLQNLGVAILP
AWSAADAVRSGEMEIVLPEFAVPALPLNAVYADTQWMSLRARCFLDLLIARSHRFSEDVDGAGPPRRF

Specific function: Unknown

COG id: COG0583

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1786401, Length=283, Percent_Identity=30.7420494699647, Blast_Score=150, Evalue=9e-38,
Organism=Escherichia coli, GI87081978, Length=286, Percent_Identity=30.7692307692308, Blast_Score=144, Evalue=7e-36,
Organism=Escherichia coli, GI1789440, Length=285, Percent_Identity=29.1228070175439, Blast_Score=137, Evalue=6e-34,
Organism=Escherichia coli, GI1787128, Length=292, Percent_Identity=28.0821917808219, Blast_Score=127, Evalue=7e-31,
Organism=Escherichia coli, GI145693193, Length=290, Percent_Identity=26.8965517241379, Blast_Score=120, Evalue=9e-29,
Organism=Escherichia coli, GI1789639, Length=289, Percent_Identity=25.2595155709343, Blast_Score=120, Evalue=1e-28,
Organism=Escherichia coli, GI1787589, Length=269, Percent_Identity=25.6505576208178, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI1788706, Length=243, Percent_Identity=27.9835390946502, Blast_Score=84, Evalue=8e-18,
Organism=Escherichia coli, GI145693105, Length=157, Percent_Identity=30.5732484076433, Blast_Score=72, Evalue=6e-14,
Organism=Escherichia coli, GI1787601, Length=147, Percent_Identity=31.2925170068027, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI1788297, Length=118, Percent_Identity=30.5084745762712, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1789173, Length=273, Percent_Identity=23.0769230769231, Blast_Score=65, Evalue=7e-12,
Organism=Escherichia coli, GI1786448, Length=144, Percent_Identity=27.0833333333333, Blast_Score=63, Evalue=2e-11,
Organism=Escherichia coli, GI157672245, Length=151, Percent_Identity=29.1390728476821, Blast_Score=62, Evalue=4e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 34217; Mature: 34217

Theoretical pI: Translated: 8.89; Mature: 8.89

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDRLDCLRAFVKTMEGGSFSGAAKELGLGQPAVSKRIALLEKEFGSQLFMRNTRKLTPTR
CCHHHHHHHHHHHHCCCCCCCHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCH
EAHRIYDLARQALSCIEMARASIAEAPAVPTGMLRLGVPSSFGRHYIMPVIEQYLRDYPQ
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEECCCCCCCHHHHHHHHHHHHHCCCC
VKVDIRFSEQTVNLVEDGIELALRIGDLESSSLKARRIGLVRRFLVATPAYLRRQPQPQL
EEEEEEECHHHHHHHHHHHHHHHEECCCCCCHHHHHHHHHHHHHHHHCCHHHHCCCCCCC
PGDLKNLHCIAYARLSPANQWAFDSELGRHVVQISASIMVDDADAMKQAVLQNLGVAILP
CCCCCCEEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHEECCHHHHHHHHHHHCCEEEEE
AWSAADAVRSGEMEIVLPEFAVPALPLNAVYADTQWMSLRARCFLDLLIARSHRFSEDVD
CCHHHHHHHCCCEEEEECCCCCCCCCCHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCCC
GAGPPRRF
CCCCCCCC
>Mature Secondary Structure
MDRLDCLRAFVKTMEGGSFSGAAKELGLGQPAVSKRIALLEKEFGSQLFMRNTRKLTPTR
CCHHHHHHHHHHHHCCCCCCCHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCH
EAHRIYDLARQALSCIEMARASIAEAPAVPTGMLRLGVPSSFGRHYIMPVIEQYLRDYPQ
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEECCCCCCCHHHHHHHHHHHHHCCCC
VKVDIRFSEQTVNLVEDGIELALRIGDLESSSLKARRIGLVRRFLVATPAYLRRQPQPQL
EEEEEEECHHHHHHHHHHHHHHHEECCCCCCHHHHHHHHHHHHHHHHCCHHHHCCCCCCC
PGDLKNLHCIAYARLSPANQWAFDSELGRHVVQISASIMVDDADAMKQAVLQNLGVAILP
CCCCCCEEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHEECCHHHHHHHHHHHCCEEEEE
AWSAADAVRSGEMEIVLPEFAVPALPLNAVYADTQWMSLRARCFLDLLIARSHRFSEDVD
CCHHHHHHHCCCEEEEECCCCCCCCCCHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCCC
GAGPPRRF
CCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8748036 [H]