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The map label for this gene is wrbA

Identifier: 86751604

GI number: 86751604

Start: 5093620

End: 5094219

Strand: Direct

Name: wrbA

Synonym: RPB_4506

Alternate gene names: 86751604

Gene position: 5093620-5094219 (Clockwise)

Preceding gene: 86751603

Following gene: 86751608

Centisome position: 95.54

GC content: 67.33

Gene sequence:

>600_bases
ATGGCGAAGGTTCTGGTTCTTTACTACTCGGCTTACGGCCACATCGAGACGATGGCCAATGCGGTCGCGGAAGGCGCGCG
CGAGGCCGGCGCGACGGTCGATATCAAGCGCGTCCCCGAGCTGGTGCCGCCGGACGTCGCCAAGGCGTCGTACTACAAGC
TCGACCAGGCCGCGCCGGTCGCGACCATCGACGATCTCGCCAATTACGACGCGATCATCGTCGGCACCGGCACCCGGTTC
GGCCGGATGGCGTCGCAGATGGCGAACTTCCTCGATCAGGCCGGCGGGCTGTGGGCGAAGGGCGCGCTGAACGGCAAGGT
CGGTGGCGCCTTCACCTCGACCGCGACCCAGCACGGCGGCCAGGAAACCACACTGTTCTCGATCATCACCAACCTGCTGC
ATTTCGGCATGGTGGTGGTCGGCCTCAATTACGGCTTCCAGGGCCAGATGACGCTCGGCGAAATCACCGGCGGCGCCCCT
TACGGCGCGACCACGCTGACCGGCGGCGACGGCGCGCGGCAGCCGAGCGCCAACGAACTCGCCGGCGCGCGCTATCAGGG
CAAGACCATCGCCGAGACCGCGATCAAGCTGCACGGCTGA

Upstream 100 bases:

>100_bases
GTCCTGACGAAGGAGATGGATGGCCGGGTCAAGCCCGGCCATGACGGCTGACTAACAACTCGACGACTCCCCACCCATCC
CCACCCCAACGGAGACTCCC

Downstream 100 bases:

>100_bases
TCGGCCGCGACGGGCGCGGTGCGCGATCCCGCGCGCCGCACCCAGCCGGGCCGGTCAGGCGTCGAGCGCCGGCACACCGG
CGCCGGCGTGATAGCGGCTG

Product: TrpR binding protein WrbA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 199; Mature: 198

Protein sequence:

>199_residues
MAKVLVLYYSAYGHIETMANAVAEGAREAGATVDIKRVPELVPPDVAKASYYKLDQAAPVATIDDLANYDAIIVGTGTRF
GRMASQMANFLDQAGGLWAKGALNGKVGGAFTSTATQHGGQETTLFSIITNLLHFGMVVVGLNYGFQGQMTLGEITGGAP
YGATTLTGGDGARQPSANELAGARYQGKTIAETAIKLHG

Sequences:

>Translated_199_residues
MAKVLVLYYSAYGHIETMANAVAEGAREAGATVDIKRVPELVPPDVAKASYYKLDQAAPVATIDDLANYDAIIVGTGTRF
GRMASQMANFLDQAGGLWAKGALNGKVGGAFTSTATQHGGQETTLFSIITNLLHFGMVVVGLNYGFQGQMTLGEITGGAP
YGATTLTGGDGARQPSANELAGARYQGKTIAETAIKLHG
>Mature_198_residues
AKVLVLYYSAYGHIETMANAVAEGAREAGATVDIKRVPELVPPDVAKASYYKLDQAAPVATIDDLANYDAIIVGTGTRFG
RMASQMANFLDQAGGLWAKGALNGKVGGAFTSTATQHGGQETTLFSIITNLLHFGMVVVGLNYGFQGQMTLGEITGGAPY
GATTLTGGDGARQPSANELAGARYQGKTIAETAIKLHG

Specific function: Seems To Enhance The Formation And/Or Stability Of Noncovalent Complexes Between The Trp Repressor Protein And Operator-Bearing DNA. However, Wrba Does Not Specifically Influence The Affinity Or Mode Of Binding Of Trpr To Its Operator. It Seems Possible T

COG id: COG0655

COG function: function code R; Multimeric flavodoxin WrbA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 flavodoxin-like domain

Homologues:

Organism=Escherichia coli, GI1787239, Length=200, Percent_Identity=59, Blast_Score=218, Evalue=3e-58,
Organism=Saccharomyces cerevisiae, GI6319849, Length=200, Percent_Identity=44.5, Blast_Score=163, Evalue=2e-41,
Organism=Saccharomyces cerevisiae, GI6320235, Length=199, Percent_Identity=43.21608040201, Blast_Score=154, Evalue=9e-39,
Organism=Saccharomyces cerevisiae, GI6319526, Length=201, Percent_Identity=31.8407960199005, Blast_Score=98, Evalue=1e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): WRBA_RHOP2 (Q2IRH1)

Other databases:

- EMBL:   CP000250
- RefSeq:   YP_488100.1
- ProteinModelPortal:   Q2IRH1
- SMR:   Q2IRH1
- STRING:   Q2IRH1
- GeneID:   3912322
- GenomeReviews:   CP000250_GR
- KEGG:   rpb:RPB_4506
- eggNOG:   COG0655
- HOGENOM:   HBG686708
- OMA:   TITSFHT
- ProtClustDB:   PRK03767
- BioCyc:   RPAL316058:RPB_4506-MONOMER
- HAMAP:   MF_01017
- InterPro:   IPR008254
- InterPro:   IPR010089
- InterPro:   IPR005025
- TIGRFAMs:   TIGR01755

Pfam domain/function: PF03358 FMN_red

EC number: NA

Molecular weight: Translated: 20646; Mature: 20514

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: PS50902 FLAVODOXIN_LIKE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKVLVLYYSAYGHIETMANAVAEGAREAGATVDIKRVPELVPPDVAKASYYKLDQAAPV
CCEEEEEEEEHHCHHHHHHHHHHHHHHHCCCEEEHHHCCCCCCCCCCHHHHHHHCCCCCC
ATIDDLANYDAIIVGTGTRFGRMASQMANFLDQAGGLWAKGALNGKVGGAFTSTATQHGG
HHHHHHCCCCEEEEECCCHHHHHHHHHHHHHHHHCCEEECCCCCCCCCCCCCCHHHHCCC
QETTLFSIITNLLHFGMVVVGLNYGFQGQMTLGEITGGAPYGATTLTGGDGARQPSANEL
CHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCCCCEEEECCCCCCCCCCHHH
AGARYQGKTIAETAIKLHG
CCCCCCCCHHHHHHHEECC
>Mature Secondary Structure 
AKVLVLYYSAYGHIETMANAVAEGAREAGATVDIKRVPELVPPDVAKASYYKLDQAAPV
CEEEEEEEEHHCHHHHHHHHHHHHHHHCCCEEEHHHCCCCCCCCCCHHHHHHHCCCCCC
ATIDDLANYDAIIVGTGTRFGRMASQMANFLDQAGGLWAKGALNGKVGGAFTSTATQHGG
HHHHHHCCCCEEEEECCCHHHHHHHHHHHHHHHHCCEEECCCCCCCCCCCCCCHHHHCCC
QETTLFSIITNLLHFGMVVVGLNYGFQGQMTLGEITGGAPYGATTLTGGDGARQPSANEL
CHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCCCCEEEECCCCCCCCCCHHH
AGARYQGKTIAETAIKLHG
CCCCCCCCHHHHHHHEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA