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The map label for this gene is 86751569

Identifier: 86751569

GI number: 86751569

Start: 5061218

End: 5062258

Strand: Direct

Name: 86751569

Synonym: RPB_4471

Alternate gene names: NA

Gene position: 5061218-5062258 (Clockwise)

Preceding gene: 86751568

Following gene: 86751570

Centisome position: 94.93

GC content: 65.03

Gene sequence:

>1041_bases
ATGAATCTCGCCGACCTGAACACGATCGCCCGCGCCATGGTCGCGCCCGGCAAGGGCATTCTCGCCGCCGACGAATCCTC
GGGAACCATCAAGAAGCGGTTCGACGTGATCGGCGTCGAATCGACCGAGACCAGCCGCCGCGACTATCGCGAGATGATGT
TCCGCTCCAAAGAGGCGATGAACGACTACATCTCCGGCGTGATCCTGTACGACGAGACGATCTGGCAGAACGCCGCCGAC
GGTACGCCCTTGGTGAAGCTGATCGAGCAGGCCGGCAGCATCCCCGGCATCAAGGTCGACGAAGGCACCCAGCCACTGCC
GAACTGCCCGGGCGAAACCATCACCGTCGGTCTCGACAAGCTCGCCGAGCGGCTGGCGAAATATTACAAGCAGGGCGCGC
GCTTCGCGAAATGGCGCGCGGTGATCGATATCGGCGCCGGCATTCCGAGCTACGCCGCGATCCACACCAACGCGCATGCG
CTGGCGCGCTATGCGGCGCTGTGCCAGCAGGCGCAGATCGTGCCGATCGTCGAGCCCGAGGTGCTGATGGACGGCGACCA
CGACATCGACCGCTGCTACGAGGTCACCGAATTCGTGCTCAAGGAGACCTTCCAGGAGCTGTACTACCAGAAGGTCGCGC
TCGAAGGCATGGTGCTGAAGCCGAACATGGCGGTCGCCGGCAAGAAGTCGGCCAAGTCGGCCGGCGTGCAGGAAGTCGCG
GAGAAGACCGTGAAGCTGTTGAAGGCCTGCGTGCCGTCGGCGGTGCCGGGCATCGCGTTCCTGTCGGGCGGCCAGTCCGA
CGAGGACGCCACCGCGCATCTCGACGCCATGAACAAAATCGGCGGCCTGACTTCGGGCCTTCCTTGGGGCCTCACCTTCT
CCTACGGCCGTGCCCTGCAGGCCGCGCCGCAGAAGGCGTGGTCCGGCAAGGCCGACAACGTCGCGGCCGGCCAGGCCGCA
TTCACCCACCGGGCGAAAATGAACTCGCTCGCCAGCAAGGGCGAGTGGTCATCCGACCTCGAAAGCAAGAAGGCCGCATA
A

Upstream 100 bases:

>100_bases
GCCCTCGCCATTTTCCTGGGCATTGTCTAAGACGGTCTGGACGTTCGAGACCCTTGCGGACCGCAAAACCAACCAAGAAA
ACAGCCCAACGGAGAAGCCG

Downstream 100 bases:

>100_bases
CGCCGATGGCCAAGCCTGCCCCGCCGCGCCCGGCGCCGCGCCTCTATCTCGCGACGCCGGTCGTGGACGATCCCGCACAG
TTGCTGGCAGCGTTGCCGCA

Product: fructose-bisphosphate aldolase

Products: NA

Alternate protein names: Fructose-biphosphate aldolase class I; FBP aldolase [H]

Number of amino acids: Translated: 346; Mature: 346

Protein sequence:

>346_residues
MNLADLNTIARAMVAPGKGILAADESSGTIKKRFDVIGVESTETSRRDYREMMFRSKEAMNDYISGVILYDETIWQNAAD
GTPLVKLIEQAGSIPGIKVDEGTQPLPNCPGETITVGLDKLAERLAKYYKQGARFAKWRAVIDIGAGIPSYAAIHTNAHA
LARYAALCQQAQIVPIVEPEVLMDGDHDIDRCYEVTEFVLKETFQELYYQKVALEGMVLKPNMAVAGKKSAKSAGVQEVA
EKTVKLLKACVPSAVPGIAFLSGGQSDEDATAHLDAMNKIGGLTSGLPWGLTFSYGRALQAAPQKAWSGKADNVAAGQAA
FTHRAKMNSLASKGEWSSDLESKKAA

Sequences:

>Translated_346_residues
MNLADLNTIARAMVAPGKGILAADESSGTIKKRFDVIGVESTETSRRDYREMMFRSKEAMNDYISGVILYDETIWQNAAD
GTPLVKLIEQAGSIPGIKVDEGTQPLPNCPGETITVGLDKLAERLAKYYKQGARFAKWRAVIDIGAGIPSYAAIHTNAHA
LARYAALCQQAQIVPIVEPEVLMDGDHDIDRCYEVTEFVLKETFQELYYQKVALEGMVLKPNMAVAGKKSAKSAGVQEVA
EKTVKLLKACVPSAVPGIAFLSGGQSDEDATAHLDAMNKIGGLTSGLPWGLTFSYGRALQAAPQKAWSGKADNVAAGQAA
FTHRAKMNSLASKGEWSSDLESKKAA
>Mature_346_residues
MNLADLNTIARAMVAPGKGILAADESSGTIKKRFDVIGVESTETSRRDYREMMFRSKEAMNDYISGVILYDETIWQNAAD
GTPLVKLIEQAGSIPGIKVDEGTQPLPNCPGETITVGLDKLAERLAKYYKQGARFAKWRAVIDIGAGIPSYAAIHTNAHA
LARYAALCQQAQIVPIVEPEVLMDGDHDIDRCYEVTEFVLKETFQELYYQKVALEGMVLKPNMAVAGKKSAKSAGVQEVA
EKTVKLLKACVPSAVPGIAFLSGGQSDEDATAHLDAMNKIGGLTSGLPWGLTFSYGRALQAAPQKAWSGKADNVAAGQAA
FTHRAKMNSLASKGEWSSDLESKKAA

Specific function: Unknown

COG id: COG3588

COG function: function code G; Fructose-1,6-bisphosphate aldolase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class I fructose-bisphosphate aldolase family [H]

Homologues:

Organism=Homo sapiens, GI34577112, Length=342, Percent_Identity=51.1695906432749, Blast_Score=340, Evalue=9e-94,
Organism=Homo sapiens, GI34577110, Length=342, Percent_Identity=51.1695906432749, Blast_Score=340, Evalue=9e-94,
Organism=Homo sapiens, GI4557305, Length=342, Percent_Identity=51.1695906432749, Blast_Score=340, Evalue=9e-94,
Organism=Homo sapiens, GI193794814, Length=342, Percent_Identity=51.1695906432749, Blast_Score=340, Evalue=9e-94,
Organism=Homo sapiens, GI4885063, Length=342, Percent_Identity=49.7076023391813, Blast_Score=327, Evalue=1e-89,
Organism=Homo sapiens, GI40354205, Length=332, Percent_Identity=50, Blast_Score=314, Evalue=9e-86,
Organism=Caenorhabditis elegans, GI25150450, Length=334, Percent_Identity=49.7005988023952, Blast_Score=334, Evalue=3e-92,
Organism=Caenorhabditis elegans, GI71983985, Length=332, Percent_Identity=51.2048192771084, Blast_Score=328, Evalue=3e-90,
Organism=Caenorhabditis elegans, GI71983990, Length=230, Percent_Identity=50.4347826086956, Blast_Score=228, Evalue=4e-60,
Organism=Drosophila melanogaster, GI45553577, Length=330, Percent_Identity=53.3333333333333, Blast_Score=342, Evalue=3e-94,
Organism=Drosophila melanogaster, GI24650282, Length=332, Percent_Identity=52.710843373494, Blast_Score=341, Evalue=4e-94,
Organism=Drosophila melanogaster, GI24650280, Length=332, Percent_Identity=52.710843373494, Blast_Score=341, Evalue=4e-94,
Organism=Drosophila melanogaster, GI24650278, Length=332, Percent_Identity=52.710843373494, Blast_Score=341, Evalue=4e-94,
Organism=Drosophila melanogaster, GI221459619, Length=334, Percent_Identity=52.3952095808383, Blast_Score=340, Evalue=7e-94,
Organism=Drosophila melanogaster, GI24650288, Length=334, Percent_Identity=52.3952095808383, Blast_Score=340, Evalue=7e-94,
Organism=Drosophila melanogaster, GI24650304, Length=332, Percent_Identity=44.578313253012, Blast_Score=298, Evalue=3e-81,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000741
- InterPro:   IPR013785 [H]

Pfam domain/function: PF00274 Glycolytic [H]

EC number: =4.1.2.13 [H]

Molecular weight: Translated: 37201; Mature: 37201

Theoretical pI: Translated: 6.68; Mature: 6.68

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNLADLNTIARAMVAPGKGILAADESSGTIKKRFDVIGVESTETSRRDYREMMFRSKEAM
CCCHHHHHHHHHHHCCCCCEEEECCCCCCHHHHHEEECCCCCCHHHHHHHHHHHHHHHHH
NDYISGVILYDETIWQNAADGTPLVKLIEQAGSIPGIKVDEGTQPLPNCPGETITVGLDK
HHHHCEEEEECHHHHCCCCCCCHHHHHHHHHCCCCCEEECCCCCCCCCCCCCEEEECHHH
LAERLAKYYKQGARFAKWRAVIDIGAGIPSYAAIHTNAHALARYAALCQQAQIVPIVEPE
HHHHHHHHHHHCCHHHHHHHHEEECCCCCCCCEECCCHHHHHHHHHHHHCCCCCEECCCH
VLMDGDHDIDRCYEVTEFVLKETFQELYYQKVALEGMVLKPNMAVAGKKSAKSAGVQEVA
HEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEECCCCCCCCCCHHHHCCHHHHH
EKTVKLLKACVPSAVPGIAFLSGGQSDEDATAHLDAMNKIGGLTSGLPWGLTFSYGRALQ
HHHHHHHHHHHHHCCCCHHEECCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHH
AAPQKAWSGKADNVAAGQAAFTHRAKMNSLASKGEWSSDLESKKAA
HCHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHCCC
>Mature Secondary Structure
MNLADLNTIARAMVAPGKGILAADESSGTIKKRFDVIGVESTETSRRDYREMMFRSKEAM
CCCHHHHHHHHHHHCCCCCEEEECCCCCCHHHHHEEECCCCCCHHHHHHHHHHHHHHHHH
NDYISGVILYDETIWQNAADGTPLVKLIEQAGSIPGIKVDEGTQPLPNCPGETITVGLDK
HHHHCEEEEECHHHHCCCCCCCHHHHHHHHHCCCCCEEECCCCCCCCCCCCCEEEECHHH
LAERLAKYYKQGARFAKWRAVIDIGAGIPSYAAIHTNAHALARYAALCQQAQIVPIVEPE
HHHHHHHHHHHCCHHHHHHHHEEECCCCCCCCEECCCHHHHHHHHHHHHCCCCCEECCCH
VLMDGDHDIDRCYEVTEFVLKETFQELYYQKVALEGMVLKPNMAVAGKKSAKSAGVQEVA
HEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEECCCCCCCCCCHHHHCCHHHHH
EKTVKLLKACVPSAVPGIAFLSGGQSDEDATAHLDAMNKIGGLTSGLPWGLTFSYGRALQ
HHHHHHHHHHHHHCCCCHHEECCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHH
AAPQKAWSGKADNVAAGQAAFTHRAKMNSLASKGEWSSDLESKKAA
HCHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12024217 [H]