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The map label for this gene is dsbD [H]

Identifier: 86751462

GI number: 86751462

Start: 4943741

End: 4945552

Strand: Direct

Name: dsbD [H]

Synonym: RPB_4360

Alternate gene names: 86751462

Gene position: 4943741-4945552 (Clockwise)

Preceding gene: 86751459

Following gene: 86751463

Centisome position: 92.72

GC content: 72.46

Gene sequence:

>1812_bases
ATGACAGACCGACTTTTCCGCGCGCTCATCCTGCTCGTCGCGATCGCAGCCGGCGTCCACGGCGCGCTCGCCGCCGGTCC
GGCGCAGGCCGCGCCGTTCGAACTCAGCGTACAGCCCGGCGCCGACGGCGTCGATCTGACCTGGCGGATCGCCCCGGACG
ATTATCTCTATCGCGACAAGATCGTCGTCACCACCGCCGACGGCGCGCGCGTCGCGCTGCGGACGCCGGCCGGCGAGATC
AAGGACGATCCGAATTTCGGCATGACCGAAATCTATCACCGCAGCCTGACCGCGACGATCCCCGCCGACGCGGTGAACGG
CGCGAGCCGGCTGACGGTGAGCTATCAGGGCTGCGCCGAGCGCGGCATCTGCTATCCGCCGGTGACGGCGAGCGTCGATC
TCGGCACCTATCAGGTGTCGATCGCCGGCGGCGCGACGCCGAGTGCGAGCCCGGCCTGGCCCTCGGACATGCCGGCGCTG
CCGGACCTCGCCGCGCCCGCGGAGACGCCCGCACCCTTCGCGGCTTCGGTGCTGCCGTCGATGACGCAAGGCTGGTTGCC
GCTGCTGCTGGCGTTCGCCGGGTTCGGGCTGCTGCTGGCGTTCACGCCCTGCGTGCTGCCGATGATGCCGATCGTCGCCG
GCATGCTGACGCGCTCCGGCCCCAACCTCTCGCCGGCGCGCGGCTTCGCACTGGCCTCGATCTACACGCTGGCGATGGCC
GCGGCCTATGCGACGCTCGGCGTCGCGGCGGCGTGGTCCGGGCAGAATCTGCAGAGCGCGTTGCAGGCGCCGCTGGCGCT
GGCGGTGATGGCGGCGATCTATGTCGCGCTGGCGCTGTCGAGCTTCGGCCTGTTCGAGCTGCAACTGCCGGCGCGGTTCG
GCGGCGATCTCGCCGGCCGCCTGCACGGCCGCGCCGGACCGTTGCTCGGCGCCGCCGCGCTCGGCTTCACCTCGGCGCTG
ATCGTCGGGCCGTGCGTGACCCCACCGCTCGCCGCGGCGCTGCTCTACGTCGCACAGACCGGTGACATGCTGCGCGGCGC
GGCGGCGCTGTTCGCGCTCGGCCTCGGCATGGGCTTTCCGCTGATCCTGGTCGGGCTGTTCGGCGCCGGCGTGCTGCCGC
GCTCGGGGCCGTGGCTGGTGACGATCCGCCAATTGTTCGGCTTCGCCTTTCTCGGCCTCGCGGTGGCGTTGATTGCGCGG
GTGCTGCCGGGATCGGTGGCGCTGCTGCTGTGGGCCGGCCTCGCCATCGGCCTCGCGGCGTTTCTCGGCGCGTTCGACCG
GCTCGCGCCGCAGGGCGGCGCGACGCGGCGTTTCGGCAAGGCGGCGGGCGTCGCCGTGTTCGTCTATGGCGCGACGCTGA
TCGTCGGCGCCGCCGGCGGCAGCGACGATCCGCTGCGGCCGCTCGCGGTGTTCGGCGCCGACCAGCCAGCGGCGGCCGCG
ATGTTCGCCGCGCCGGTGACGTCGATCCGCGCGCTGGATCAGGCGATCAGCGACGGCCGCGCGCGCGGCAAGCCGATCAT
GATCGACTTCTCCGCCGACTGGTGCACCTCGTGCAAGACCATGGAGCGCGAGGTGTTCGGCGATCCCGCGATCCGGCAGC
GGCTGCAGGATCTCACGCTGATCCGCGCCGACGTCACCCGGTCCGACGCCGAGACCGCGGCGCTGATGAAGCGCTTCGAC
GTCGTCGGGCCACCGACGGTGGTGTTTCTCGATCGGCGCGACGGCCGCGAAATCACCGCCGCCCGCACCGTCGGCGAAGT
GACCGCCGACAGCTTCGTCAAGACGCTGCAGCGCGTCGGCGCGGCGTCCTGA

Upstream 100 bases:

>100_bases
GCGAGCTGTTCTCCACGTGCCTGCTCTCGGCCGCCAGCCTTAAGGCTGGCTTAAGCTGGGCGTCGACATTGCCGGTGCTC
AAGTCAGGCATCGGGGAACC

Downstream 100 bases:

>100_bases
CCCACACTCTTTCAACCGGAGTCGACCATGAACCGCAGACAATCCCTGATGATCCTCGGCGCGCTCGCGACCGTGCCGCT
GGTGAAGTTCTTCGGCGCAC

Product: thiol:disulfide interchange protein

Products: NA

Alternate protein names: Protein-disulfide reductase; Disulfide reductase [H]

Number of amino acids: Translated: 603; Mature: 602

Protein sequence:

>603_residues
MTDRLFRALILLVAIAAGVHGALAAGPAQAAPFELSVQPGADGVDLTWRIAPDDYLYRDKIVVTTADGARVALRTPAGEI
KDDPNFGMTEIYHRSLTATIPADAVNGASRLTVSYQGCAERGICYPPVTASVDLGTYQVSIAGGATPSASPAWPSDMPAL
PDLAAPAETPAPFAASVLPSMTQGWLPLLLAFAGFGLLLAFTPCVLPMMPIVAGMLTRSGPNLSPARGFALASIYTLAMA
AAYATLGVAAAWSGQNLQSALQAPLALAVMAAIYVALALSSFGLFELQLPARFGGDLAGRLHGRAGPLLGAAALGFTSAL
IVGPCVTPPLAAALLYVAQTGDMLRGAAALFALGLGMGFPLILVGLFGAGVLPRSGPWLVTIRQLFGFAFLGLAVALIAR
VLPGSVALLLWAGLAIGLAAFLGAFDRLAPQGGATRRFGKAAGVAVFVYGATLIVGAAGGSDDPLRPLAVFGADQPAAAA
MFAAPVTSIRALDQAISDGRARGKPIMIDFSADWCTSCKTMEREVFGDPAIRQRLQDLTLIRADVTRSDAETAALMKRFD
VVGPPTVVFLDRRDGREITAARTVGEVTADSFVKTLQRVGAAS

Sequences:

>Translated_603_residues
MTDRLFRALILLVAIAAGVHGALAAGPAQAAPFELSVQPGADGVDLTWRIAPDDYLYRDKIVVTTADGARVALRTPAGEI
KDDPNFGMTEIYHRSLTATIPADAVNGASRLTVSYQGCAERGICYPPVTASVDLGTYQVSIAGGATPSASPAWPSDMPAL
PDLAAPAETPAPFAASVLPSMTQGWLPLLLAFAGFGLLLAFTPCVLPMMPIVAGMLTRSGPNLSPARGFALASIYTLAMA
AAYATLGVAAAWSGQNLQSALQAPLALAVMAAIYVALALSSFGLFELQLPARFGGDLAGRLHGRAGPLLGAAALGFTSAL
IVGPCVTPPLAAALLYVAQTGDMLRGAAALFALGLGMGFPLILVGLFGAGVLPRSGPWLVTIRQLFGFAFLGLAVALIAR
VLPGSVALLLWAGLAIGLAAFLGAFDRLAPQGGATRRFGKAAGVAVFVYGATLIVGAAGGSDDPLRPLAVFGADQPAAAA
MFAAPVTSIRALDQAISDGRARGKPIMIDFSADWCTSCKTMEREVFGDPAIRQRLQDLTLIRADVTRSDAETAALMKRFD
VVGPPTVVFLDRRDGREITAARTVGEVTADSFVKTLQRVGAAS
>Mature_602_residues
TDRLFRALILLVAIAAGVHGALAAGPAQAAPFELSVQPGADGVDLTWRIAPDDYLYRDKIVVTTADGARVALRTPAGEIK
DDPNFGMTEIYHRSLTATIPADAVNGASRLTVSYQGCAERGICYPPVTASVDLGTYQVSIAGGATPSASPAWPSDMPALP
DLAAPAETPAPFAASVLPSMTQGWLPLLLAFAGFGLLLAFTPCVLPMMPIVAGMLTRSGPNLSPARGFALASIYTLAMAA
AYATLGVAAAWSGQNLQSALQAPLALAVMAAIYVALALSSFGLFELQLPARFGGDLAGRLHGRAGPLLGAAALGFTSALI
VGPCVTPPLAAALLYVAQTGDMLRGAAALFALGLGMGFPLILVGLFGAGVLPRSGPWLVTIRQLFGFAFLGLAVALIARV
LPGSVALLLWAGLAIGLAAFLGAFDRLAPQGGATRRFGKAAGVAVFVYGATLIVGAAGGSDDPLRPLAVFGADQPAAAAM
FAAPVTSIRALDQAISDGRARGKPIMIDFSADWCTSCKTMEREVFGDPAIRQRLQDLTLIRADVTRSDAETAALMKRFDV
VGPPTVVFLDRRDGREITAARTVGEVTADSFVKTLQRVGAAS

Specific function: Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a

COG id: COG4232

COG function: function code OC; Thiol:disulfide interchange protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thioredoxin domain [H]

Homologues:

Organism=Escherichia coli, GI1790578, Length=610, Percent_Identity=35.4098360655738, Blast_Score=324, Evalue=1e-89,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003834
- InterPro:   IPR022910
- InterPro:   IPR017936
- InterPro:   IPR012336
- InterPro:   IPR017937
- InterPro:   IPR013766
- InterPro:   IPR012335 [H]

Pfam domain/function: PF02683 DsbD; PF00085 Thioredoxin [H]

EC number: =1.8.1.8 [H]

Molecular weight: Translated: 62069; Mature: 61938

Theoretical pI: Translated: 7.78; Mature: 7.78

Prosite motif: PS00194 THIOREDOXIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDRLFRALILLVAIAAGVHGALAAGPAQAAPFELSVQPGADGVDLTWRIAPDDYLYRDK
CCHHHHHHHHHHHHHHHCCCHHHHCCCCCCCCEEEEECCCCCCCEEEEEECCCCEEEECE
IVVTTADGARVALRTPAGEIKDDPNFGMTEIYHRSLTATIPADAVNGASRLTVSYQGCAE
EEEEECCCCEEEEECCCCCCCCCCCCCHHHHHHHHHCEECCHHHCCCCCEEEEEECCHHH
RGICYPPVTASVDLGTYQVSIAGGATPSASPAWPSDMPALPDLAAPAETPAPFAASVLPS
CCCCCCCCCCEEECCEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHH
MTQGWLPLLLAFAGFGLLLAFTPCVLPMMPIVAGMLTRSGPNLSPARGFALASIYTLAMA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHH
AAYATLGVAAAWSGQNLQSALQAPLALAVMAAIYVALALSSFGLFELQLPARFGGDLAGR
HHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECHHHCCCHHHH
LHGRAGPLLGAAALGFTSALIVGPCVTPPLAAALLYVAQTGDMLRGAAALFALGLGMGFP
CCCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCHH
LILVGLFGAGVLPRSGPWLVTIRQLFGFAFLGLAVALIARVLPGSVALLLWAGLAIGLAA
HHHHHHHCCCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHH
FLGAFDRLAPQGGATRRFGKAAGVAVFVYGATLIVGAAGGSDDPLRPLAVFGADQPAAAA
HHHHHHHHCCCCCCCHHHHHHCCEEEEEEEEEHEEECCCCCCCCCCCEEEECCCCCHHHH
MFAAPVTSIRALDQAISDGRARGKPIMIDFSADWCTSCKTMEREVFGDPAIRQRLQDLTL
HHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCHHHHHHHHHHHHHCCCHHHHHHHHHHHH
IRADVTRSDAETAALMKRFDVVGPPTVVFLDRRDGREITAARTVGEVTADSFVKTLQRVG
HHHHCCCCHHHHHHHHHHHCCCCCCEEEEEECCCCCEEHHHHHHHHHHHHHHHHHHHHHC
AAS
CCC
>Mature Secondary Structure 
TDRLFRALILLVAIAAGVHGALAAGPAQAAPFELSVQPGADGVDLTWRIAPDDYLYRDK
CHHHHHHHHHHHHHHHCCCHHHHCCCCCCCCEEEEECCCCCCCEEEEEECCCCEEEECE
IVVTTADGARVALRTPAGEIKDDPNFGMTEIYHRSLTATIPADAVNGASRLTVSYQGCAE
EEEEECCCCEEEEECCCCCCCCCCCCCHHHHHHHHHCEECCHHHCCCCCEEEEEECCHHH
RGICYPPVTASVDLGTYQVSIAGGATPSASPAWPSDMPALPDLAAPAETPAPFAASVLPS
CCCCCCCCCCEEECCEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHH
MTQGWLPLLLAFAGFGLLLAFTPCVLPMMPIVAGMLTRSGPNLSPARGFALASIYTLAMA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHH
AAYATLGVAAAWSGQNLQSALQAPLALAVMAAIYVALALSSFGLFELQLPARFGGDLAGR
HHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECHHHCCCHHHH
LHGRAGPLLGAAALGFTSALIVGPCVTPPLAAALLYVAQTGDMLRGAAALFALGLGMGFP
CCCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCHH
LILVGLFGAGVLPRSGPWLVTIRQLFGFAFLGLAVALIARVLPGSVALLLWAGLAIGLAA
HHHHHHHCCCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHH
FLGAFDRLAPQGGATRRFGKAAGVAVFVYGATLIVGAAGGSDDPLRPLAVFGADQPAAAA
HHHHHHHHCCCCCCCHHHHHHCCEEEEEEEEEHEEECCCCCCCCCCCEEEECCCCCHHHH
MFAAPVTSIRALDQAISDGRARGKPIMIDFSADWCTSCKTMEREVFGDPAIRQRLQDLTL
HHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCHHHHHHHHHHHHHCCCHHHHHHHHHHHH
IRADVTRSDAETAALMKRFDVVGPPTVVFLDRRDGREITAARTVGEVTADSFVKTLQRVG
HHHHCCCCHHHHHHHHHHHCCCCCCEEEEEECCCCCEEHHHHHHHHHHHHHHHHHHHHHC
AAS
CCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA