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The map label for this gene is qseB [H]

Identifier: 86751461

GI number: 86751461

Start: 4942980

End: 4943639

Strand: Reverse

Name: qseB [H]

Synonym: RPB_4359

Alternate gene names: 86751461

Gene position: 4943639-4942980 (Counterclockwise)

Preceding gene: 86751465

Following gene: 86751460

Centisome position: 92.72

GC content: 70.0

Gene sequence:

>660_bases
ATGAGAATCCTGGTGGTCGAAGACGACGCGATGATCGCGGACGGCATTCGTGCCGGGCTGACGCTGGCCGGCGCCAGTAT
CGATTGCGTCGCCAATTGCGAGGATGCGGCGGCCGCGCTCGCCGCCAATACGTTCTCGGCGGTGGTGCTCGACGTCATGC
TGCCGGACGGCAGCGGCCTCGATCTGTTGCGCAGATTGCGCGCCGGCGGAGACGCCACGCCGGTGCTGCTGCTGACCGCG
CTCGACGAGGTCGGCGACCGGATCGCCGGGCTCGACTCCGGTGCCGACGATCATCTCGGCAAGCCGTTCGACCTCGACGA
ACTCGGCGCGCGGTTGCGCGCGATCATCCGCCGCCGCGACGGCCGCGCCGCGACCTGCCTCGAACACGGCGCGATCCGGC
TGTTTCCGGCGGAGAGCAACGCGACGCTCGACGGCGCGCCGGTGCCGCTGTCGCGCCGCGAATTCGCGGTGCTGCACGCG
CTGATGGAGCGGCCCGGCGTGATCCGCTCGCGCGGCGAACTCGAAGAGCGGCTGTACGGCTGGGGCGACGAGGTCGACAG
CAACGCCGTCGAAGTTCACATCCACAATCTGCGCGCCAAGCTCGGTCGCGCCGCGATCGAGACCGTGCGCGGCGTCGGCT
ATCGGATCAAACCGCGATGA

Upstream 100 bases:

>100_bases
GTTCCCCGATGCCTGACTTGAGCACCGGCAATGTCGACGCCCAGCTTAAGCCAGCCTTAAGGCTGGCGGCCGAGAGCAGG
CACGTGGAGAACAGCTCGCG

Downstream 100 bases:

>100_bases
TCGGCTCGCTGCGCCTTCGGCTGTTTCTGGTGCTGTTCGGCGCCACCGGCATCGTCTGGATCGCCGCGGTGATGTGGATC
TACACGAGCAGCCAGCGCGA

Product: two component transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 219; Mature: 219

Protein sequence:

>219_residues
MRILVVEDDAMIADGIRAGLTLAGASIDCVANCEDAAAALAANTFSAVVLDVMLPDGSGLDLLRRLRAGGDATPVLLLTA
LDEVGDRIAGLDSGADDHLGKPFDLDELGARLRAIIRRRDGRAATCLEHGAIRLFPAESNATLDGAPVPLSRREFAVLHA
LMERPGVIRSRGELEERLYGWGDEVDSNAVEVHIHNLRAKLGRAAIETVRGVGYRIKPR

Sequences:

>Translated_219_residues
MRILVVEDDAMIADGIRAGLTLAGASIDCVANCEDAAAALAANTFSAVVLDVMLPDGSGLDLLRRLRAGGDATPVLLLTA
LDEVGDRIAGLDSGADDHLGKPFDLDELGARLRAIIRRRDGRAATCLEHGAIRLFPAESNATLDGAPVPLSRREFAVLHA
LMERPGVIRSRGELEERLYGWGDEVDSNAVEVHIHNLRAKLGRAAIETVRGVGYRIKPR
>Mature_219_residues
MRILVVEDDAMIADGIRAGLTLAGASIDCVANCEDAAAALAANTFSAVVLDVMLPDGSGLDLLRRLRAGGDATPVLLLTA
LDEVGDRIAGLDSGADDHLGKPFDLDELGARLRAIIRRRDGRAATCLEHGAIRLFPAESNATLDGAPVPLSRREFAVLHA
LMERPGVIRSRGELEERLYGWGDEVDSNAVEVHIHNLRAKLGRAAIETVRGVGYRIKPR

Specific function: Member of a two-component regulatory system qseB/qseC. Activates the flagella regulon by activating transcription of flhDC [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1789402, Length=216, Percent_Identity=48.1481481481481, Blast_Score=199, Evalue=9e-53,
Organism=Escherichia coli, GI1790552, Length=216, Percent_Identity=42.5925925925926, Blast_Score=167, Evalue=6e-43,
Organism=Escherichia coli, GI87082012, Length=218, Percent_Identity=37.1559633027523, Blast_Score=137, Evalue=8e-34,
Organism=Escherichia coli, GI1786784, Length=225, Percent_Identity=32.8888888888889, Blast_Score=124, Evalue=4e-30,
Organism=Escherichia coli, GI1789809, Length=229, Percent_Identity=34.4978165938865, Blast_Score=118, Evalue=3e-28,
Organism=Escherichia coli, GI1786599, Length=225, Percent_Identity=34.2222222222222, Blast_Score=116, Evalue=9e-28,
Organism=Escherichia coli, GI1787375, Length=223, Percent_Identity=29.5964125560538, Blast_Score=115, Evalue=2e-27,
Organism=Escherichia coli, GI1790860, Length=222, Percent_Identity=32.8828828828829, Blast_Score=112, Evalue=3e-26,
Organism=Escherichia coli, GI2367329, Length=226, Percent_Identity=35.3982300884956, Blast_Score=108, Evalue=2e-25,
Organism=Escherichia coli, GI1788394, Length=228, Percent_Identity=31.5789473684211, Blast_Score=96, Evalue=1e-21,
Organism=Escherichia coli, GI1786911, Length=235, Percent_Identity=32.7659574468085, Blast_Score=93, Evalue=1e-20,
Organism=Escherichia coli, GI1787229, Length=220, Percent_Identity=31.3636363636364, Blast_Score=89, Evalue=3e-19,
Organism=Escherichia coli, GI1790863, Length=228, Percent_Identity=27.6315789473684, Blast_Score=84, Evalue=5e-18,
Organism=Escherichia coli, GI1788550, Length=161, Percent_Identity=29.8136645962733, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI145693140, Length=234, Percent_Identity=28.2051282051282, Blast_Score=64, Evalue=6e-12,
Organism=Escherichia coli, GI1790299, Length=105, Percent_Identity=31.4285714285714, Blast_Score=60, Evalue=9e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 23389; Mature: 23389

Theoretical pI: Translated: 5.15; Mature: 5.15

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRILVVEDDAMIADGIRAGLTLAGASIDCVANCEDAAAALAANTFSAVVLDVMLPDGSGL
CEEEEEECCCHHHHHHHHCEEEECCCEEEECCCHHHHHHHHHHHHHHEEEEEECCCCCCH
DLLRRLRAGGDATPVLLLTALDEVGDRIAGLDSGADDHLGKPFDLDELGARLRAIIRRRD
HHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCC
GRAATCLEHGAIRLFPAESNATLDGAPVPLSRREFAVLHALMERPGVIRSRGELEERLYG
CCEEHHHHCCCEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHC
WGDEVDSNAVEVHIHNLRAKLGRAAIETVRGVGYRIKPR
CCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHCCEEECCC
>Mature Secondary Structure
MRILVVEDDAMIADGIRAGLTLAGASIDCVANCEDAAAALAANTFSAVVLDVMLPDGSGL
CEEEEEECCCHHHHHHHHCEEEECCCEEEECCCHHHHHHHHHHHHHHEEEEEECCCCCCH
DLLRRLRAGGDATPVLLLTALDEVGDRIAGLDSGADDHLGKPFDLDELGARLRAIIRRRD
HHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCC
GRAATCLEHGAIRLFPAESNATLDGAPVPLSRREFAVLHALMERPGVIRSRGELEERLYG
CCEEHHHHCCCEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHC
WGDEVDSNAVEVHIHNLRAKLGRAAIETVRGVGYRIKPR
CCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHCCEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11677608; 12644504 [H]