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The map label for this gene is qseC [H]

Identifier: 86751460

GI number: 86751460

Start: 4941643

End: 4942983

Strand: Reverse

Name: qseC [H]

Synonym: RPB_4358

Alternate gene names: 86751460

Gene position: 4942983-4941643 (Counterclockwise)

Preceding gene: 86751461

Following gene: 86751458

Centisome position: 92.71

GC content: 71.14

Gene sequence:

>1341_bases
ATGATCGGCTCGCTGCGCCTTCGGCTGTTTCTGGTGCTGTTCGGCGCCACCGGCATCGTCTGGATCGCCGCGGTGATGTG
GATCTACACGAGCAGCCAGCGCGAGCTCGAACACGTGCTCGACGCGCGGCTGCAGGAGGCGGCCCGCATGGTGGTGTCGC
TGGTCGGCAACATGGAGGGCCGTGTTCCGGAAGCGCTGCCGGATGTGCCGGCGGCGCCGGCGACGCCAGGCAATTACGAG
CGGCAATTGTCCTGCCAGGTGTGGTCGGTGCAGGGCCGGCTGATCGCGCGCTCGGGCGGTGCGCCGGAGCAGAGTCTCAG
CGATCAGGGGGCGGGATTTTCCGAGCGGCAGATCGACGGCGAAACCTGGCGGATCTATGCGACGGAGGACGCCGCCCGCG
GCTTTCGCGTGCTGGTCGGCGACCGGCTCGGCTTGCGCGAGCGGCTCGTCGCCGATCTGATCAAGGGATTGCTGTGGCCG
GCGCTGCTGATCGCGCCGCTGCTCGGCCTGCTGATCTGGATCAGCGTCGGCCGCGGGCTGCGACCGCTGCAGGCGATTGC
GTCGGATCTGGTCGGGCGCGACGCCGACGACATGCGGCCGGTCGATGCCAGCCGCACCCCCTCCGAAGTGATGCCGCTCG
CCCGCGCGCTGAACGCGCTGTTCGACAAGGTCGCGCTGGCGCGGCGTCACGAGCGCGAGATCACCGCCTTCGCGGCGCAC
GAGCTGCGCAGTCCGCTCACCGGCCTCAAGACCCAGGCGCAAGTCGCGCTGGCGACCACCGATCCGGCGGTGGCGCGGGC
GGCGCTGCAGCAGATCCTGGTCGCGGTCGATCGCGCCACCCGGCTGGTGCGCCAGTTGCTGACGCTGGCGCGGCTCGACG
CCCAGGCCGGGACCGACGATCACGGCAGCGTCGCGATCCGGCCGCTGATCGACGAGGTGGCGCGGATGACGCCGCGCCCG
GCCGGCGTCGCGGTGGTGATCGACGACGATCTCGCCGGCGCCGACTGGCGCGGCAATCGCGAATGTCTCGAACTGGCGAT
CCGCAATCTGCACGAGAATGCGATCCAGCACATGCCGGGCGGCGGCGAGGTGCGCTGGCGCGCCGGCGCGTCGCCGCGAT
CGGTGGTGATCGAGGACAGCGGTCCCGGCGTGCCGGAGGACGAATTGCCGAAACTCGGTCAGCGCTTCTTCCGCGGGCGA
AACAAATCGGCGATCGGCAGCGGCCTCGGCCTGACCATCGCGGCGCTGGCGCTGGAGCGCACCGGCGCGGAGCTGCAGTT
CGGCAACCGCCCCGACCGCCGCGGTTTTCGCGCCGAAATCGTCCTGCGCCGAACGGTGTGA

Upstream 100 bases:

>100_bases
ACAGCAACGCCGTCGAAGTTCACATCCACAATCTGCGCGCCAAGCTCGGTCGCGCCGCGATCGAGACCGTGCGCGGCGTC
GGCTATCGGATCAAACCGCG

Downstream 100 bases:

>100_bases
TGCCGATCGATGACGGCGTCTGCGGCCTTGGGTCTTGCGGCAAGCCCTGCCACAGCTTTGCCACCGGTTTGCCGCATCCC
GGCAAGAGCCTGCCGGCGGC

Product: periplasmic sensor signal transduction histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 446; Mature: 446

Protein sequence:

>446_residues
MIGSLRLRLFLVLFGATGIVWIAAVMWIYTSSQRELEHVLDARLQEAARMVVSLVGNMEGRVPEALPDVPAAPATPGNYE
RQLSCQVWSVQGRLIARSGGAPEQSLSDQGAGFSERQIDGETWRIYATEDAARGFRVLVGDRLGLRERLVADLIKGLLWP
ALLIAPLLGLLIWISVGRGLRPLQAIASDLVGRDADDMRPVDASRTPSEVMPLARALNALFDKVALARRHEREITAFAAH
ELRSPLTGLKTQAQVALATTDPAVARAALQQILVAVDRATRLVRQLLTLARLDAQAGTDDHGSVAIRPLIDEVARMTPRP
AGVAVVIDDDLAGADWRGNRECLELAIRNLHENAIQHMPGGGEVRWRAGASPRSVVIEDSGPGVPEDELPKLGQRFFRGR
NKSAIGSGLGLTIAALALERTGAELQFGNRPDRRGFRAEIVLRRTV

Sequences:

>Translated_446_residues
MIGSLRLRLFLVLFGATGIVWIAAVMWIYTSSQRELEHVLDARLQEAARMVVSLVGNMEGRVPEALPDVPAAPATPGNYE
RQLSCQVWSVQGRLIARSGGAPEQSLSDQGAGFSERQIDGETWRIYATEDAARGFRVLVGDRLGLRERLVADLIKGLLWP
ALLIAPLLGLLIWISVGRGLRPLQAIASDLVGRDADDMRPVDASRTPSEVMPLARALNALFDKVALARRHEREITAFAAH
ELRSPLTGLKTQAQVALATTDPAVARAALQQILVAVDRATRLVRQLLTLARLDAQAGTDDHGSVAIRPLIDEVARMTPRP
AGVAVVIDDDLAGADWRGNRECLELAIRNLHENAIQHMPGGGEVRWRAGASPRSVVIEDSGPGVPEDELPKLGQRFFRGR
NKSAIGSGLGLTIAALALERTGAELQFGNRPDRRGFRAEIVLRRTV
>Mature_446_residues
MIGSLRLRLFLVLFGATGIVWIAAVMWIYTSSQRELEHVLDARLQEAARMVVSLVGNMEGRVPEALPDVPAAPATPGNYE
RQLSCQVWSVQGRLIARSGGAPEQSLSDQGAGFSERQIDGETWRIYATEDAARGFRVLVGDRLGLRERLVADLIKGLLWP
ALLIAPLLGLLIWISVGRGLRPLQAIASDLVGRDADDMRPVDASRTPSEVMPLARALNALFDKVALARRHEREITAFAAH
ELRSPLTGLKTQAQVALATTDPAVARAALQQILVAVDRATRLVRQLLTLARLDAQAGTDDHGSVAIRPLIDEVARMTPRP
AGVAVVIDDDLAGADWRGNRECLELAIRNLHENAIQHMPGGGEVRWRAGASPRSVVIEDSGPGVPEDELPKLGQRFFRGR
NKSAIGSGLGLTIAALALERTGAELQFGNRPDRRGFRAEIVLRRTV

Specific function: Member of a two-component regulatory system qseB/qseC. Activates the flagella regulon by activating transcription of flhDC. May activate qseB by phosphorylation [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1789403, Length=444, Percent_Identity=31.7567567567568, Blast_Score=192, Evalue=4e-50,
Organism=Escherichia coli, GI1790551, Length=333, Percent_Identity=27.6276276276276, Blast_Score=105, Evalue=4e-24,
Organism=Escherichia coli, GI1786600, Length=207, Percent_Identity=31.8840579710145, Blast_Score=88, Evalue=1e-18,
Organism=Escherichia coli, GI1786783, Length=370, Percent_Identity=21.6216216216216, Blast_Score=84, Evalue=2e-17,
Organism=Escherichia coli, GI1788279, Length=286, Percent_Identity=27.2727272727273, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1788393, Length=225, Percent_Identity=29.3333333333333, Blast_Score=72, Evalue=6e-14,
Organism=Escherichia coli, GI1788549, Length=189, Percent_Identity=26.984126984127, Blast_Score=66, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 48447; Mature: 48447

Theoretical pI: Translated: 9.23; Mature: 9.23

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIGSLRLRLFLVLFGATGIVWIAAVMWIYTSSQRELEHVLDARLQEAARMVVSLVGNMEG
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCC
RVPEALPDVPAAPATPGNYERQLSCQVWSVQGRLIARSGGAPEQSLSDQGAGFSERQIDG
CCCCCCCCCCCCCCCCCCCCCEEEEEEEEECCEEEECCCCCCHHHHCCCCCCCCHHCCCC
ETWRIYATEDAARGFRVLVGDRLGLRERLVADLIKGLLWPALLIAPLLGLLIWISVGRGL
CEEEEEECCHHHCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
RPLQAIASDLVGRDADDMRPVDASRTPSEVMPLARALNALFDKVALARRHEREITAFAAH
HHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ELRSPLTGLKTQAQVALATTDPAVARAALQQILVAVDRATRLVRQLLTLARLDAQAGTDD
HHHCCHHCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
HGSVAIRPLIDEVARMTPRPAGVAVVIDDDLAGADWRGNRECLELAIRNLHENAIQHMPG
CCCEEHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCC
GGEVRWRAGASPRSVVIEDSGPGVPEDELPKLGQRFFRGRNKSAIGSGLGLTIAALALER
CCCEEEECCCCCCEEEEECCCCCCCHHHHHHHHHHHHCCCCCCHHCCCHHHHHHHHHHHH
TGAELQFGNRPDRRGFRAEIVLRRTV
CCCCEECCCCCCCCCCEEEEEEEECC
>Mature Secondary Structure
MIGSLRLRLFLVLFGATGIVWIAAVMWIYTSSQRELEHVLDARLQEAARMVVSLVGNMEG
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCC
RVPEALPDVPAAPATPGNYERQLSCQVWSVQGRLIARSGGAPEQSLSDQGAGFSERQIDG
CCCCCCCCCCCCCCCCCCCCCEEEEEEEEECCEEEECCCCCCHHHHCCCCCCCCHHCCCC
ETWRIYATEDAARGFRVLVGDRLGLRERLVADLIKGLLWPALLIAPLLGLLIWISVGRGL
CEEEEEECCHHHCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
RPLQAIASDLVGRDADDMRPVDASRTPSEVMPLARALNALFDKVALARRHEREITAFAAH
HHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ELRSPLTGLKTQAQVALATTDPAVARAALQQILVAVDRATRLVRQLLTLARLDAQAGTDD
HHHCCHHCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
HGSVAIRPLIDEVARMTPRPAGVAVVIDDDLAGADWRGNRECLELAIRNLHENAIQHMPG
CCCEEHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCC
GGEVRWRAGASPRSVVIEDSGPGVPEDELPKLGQRFFRGRNKSAIGSGLGLTIAALALER
CCCEEEECCCCCCEEEEECCCCCCCHHHHHHHHHHHHCCCCCCHHCCCHHHHHHHHHHHH
TGAELQFGNRPDRRGFRAEIVLRRTV
CCCCEECCCCCCCCCCEEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796; 11929534 [H]