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The map label for this gene is glpD [H]

Identifier: 86751323

GI number: 86751323

Start: 4789888

End: 4791429

Strand: Reverse

Name: glpD [H]

Synonym: RPB_4217

Alternate gene names: 86751323

Gene position: 4791429-4789888 (Counterclockwise)

Preceding gene: 86751324

Following gene: 86751322

Centisome position: 89.87

GC content: 67.83

Gene sequence:

>1542_bases
GTGGACAGGGTTTTCGATCTCGCAATTATCGGCGGCGGGATCAACGGCTGTGGCATCGCGCGCGACGCGGCCGGCCGTGG
CAACTCCGTTTTCCTGTGCGAGATGAACGATCTGGCCAGCGGCACCTCGTCCTGGTCGACCAAGCTGATCCATGGCGGTC
TGCGCTATCTCGAATATTTCGAGTTTCGCCTGGTCCGCGAGGCGCTGATCGAGCGCGAGCGGCTGTGGCAGATCGCGCCG
CACATCATCGGTCCGCTGCGTTTCGTGTTGCCGCATCATTCCGGGTTGCGGCCGGCCTGGCGGCTGCGGCTCGGCCTGTT
TCTCTACGACTATATCGGCGGGCGTCGACTGCTGCCGCCGACGCGCTCCGTCGATCTCGCCCATGACGAGGTCGGCAAGC
CGCTGATCCCCGGGCGCTTCACCCGTGGTTTCGAATACTCCGATTGCTTCGTCGACGACGCGCGCCTCGTCGTGCTCACC
GCGCGCGACGCCGCCGAGCGCGGCGCCGAGATCCGCACCCGCACCCGCGCGGCGCAGGTTCGGCAGAGCGGCGGCATCTG
GGAGGTGACGCTCGAAGACACGCAGAGCGGCGTGCGCAACACGATCCGGGCGCGCGCGCTGGTCAATGCAGCGGGCCCAT
GGGTCGAGGCGGTGCTGGCTTCGGGCGCCGGCGTCAACGCCGCCTCCAAGGTGCGGCTGGTGCAAGGCTCGCACATCGTG
GTGCCGAAGCTGTACGATCACGACCGTGCCTATATCTTTCAGAATGCCGACGGCCGCATCGTGTTCGCGATTCCCTATCA
GGGCGACTTCACCCTGATCGGCACCACCGACCGCGACTATGACGGCGATCCCTCGCAGGTGAAGGCGACGCCGGACGAGA
TCAGCTATCTGTGCGACGCCGTCAGCGCGTATTTCGCCGGGCCGGTGAAGCCGGCTGACGTCGTCTGGACGTTCTCCGGC
GTGCGCCCGCTGTACGACGACGGCGCCAGCGAGGCCAAGGCCGCGACCCGCGACTACGTGTTCGAATTGGATACGCCGGG
CGGCGCACCGCTGCTGTCGATCTACGGCGGCAAGATCACCACCTATCGCCGACTGTCCGAAGAGGCGCTGGAGAAGCTCG
CGCCCTATCTGAAGGGCAAGACCGCCAAGGAGGGCTGGACCGCGCACCAGCCGTTGCCGGGCGGCGACTTTCCGGTCGAC
GGCGCACCCGCGCTGATCACTGAACTGACCCGCGACTATCCGTTCCTTTCCGCAGCGCACGCGCACCGCCTGGTGCACGC
CTACGGCACCCGCGCGCGCGATCTGCTCGGTGCGGCGCGGTCGATGGCCGACCTCGGCTGCGACTTCGGTGCCACATTGA
CGGAGGCGGAGGTCCGCTATCTGATCAACCGCGAATGGGCTTGCAGCGCGGACGACATCGTCTGGCGGCGATCCAAGCTC
GGCCTGCGGCTGCCGCCGTCCGCGCTCGCCGCCATCGACCAATGGATCGCCGCGTTCCGCGCGTCCGAAAAGCCGCAGCA
GCACGCGGGAGGCCGGGCATGA

Upstream 100 bases:

>100_bases
TCGTGCTTGCTTTCGTTTTTGATTGTGTTTTATTTCATCGCGAAAGAAATACGACAAAAGCGAAAGCTGCAGTGCAGCAA
TTTCGCAACAGGGAGGTGTC

Downstream 100 bases:

>100_bases
GCGTGAGCCTGGACAACGTCACCCGGACGATCGACGGGCTGCCGGCGATCTGCGACGTGTCGCTGACGCTGGAGCGCGGC
ACGCTGAGCGTGCTGCTCGG

Product: glycerol-3-phosphate dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 513; Mature: 513

Protein sequence:

>513_residues
MDRVFDLAIIGGGINGCGIARDAAGRGNSVFLCEMNDLASGTSSWSTKLIHGGLRYLEYFEFRLVREALIERERLWQIAP
HIIGPLRFVLPHHSGLRPAWRLRLGLFLYDYIGGRRLLPPTRSVDLAHDEVGKPLIPGRFTRGFEYSDCFVDDARLVVLT
ARDAAERGAEIRTRTRAAQVRQSGGIWEVTLEDTQSGVRNTIRARALVNAAGPWVEAVLASGAGVNAASKVRLVQGSHIV
VPKLYDHDRAYIFQNADGRIVFAIPYQGDFTLIGTTDRDYDGDPSQVKATPDEISYLCDAVSAYFAGPVKPADVVWTFSG
VRPLYDDGASEAKAATRDYVFELDTPGGAPLLSIYGGKITTYRRLSEEALEKLAPYLKGKTAKEGWTAHQPLPGGDFPVD
GAPALITELTRDYPFLSAAHAHRLVHAYGTRARDLLGAARSMADLGCDFGATLTEAEVRYLINREWACSADDIVWRRSKL
GLRLPPSALAAIDQWIAAFRASEKPQQHAGGRA

Sequences:

>Translated_513_residues
MDRVFDLAIIGGGINGCGIARDAAGRGNSVFLCEMNDLASGTSSWSTKLIHGGLRYLEYFEFRLVREALIERERLWQIAP
HIIGPLRFVLPHHSGLRPAWRLRLGLFLYDYIGGRRLLPPTRSVDLAHDEVGKPLIPGRFTRGFEYSDCFVDDARLVVLT
ARDAAERGAEIRTRTRAAQVRQSGGIWEVTLEDTQSGVRNTIRARALVNAAGPWVEAVLASGAGVNAASKVRLVQGSHIV
VPKLYDHDRAYIFQNADGRIVFAIPYQGDFTLIGTTDRDYDGDPSQVKATPDEISYLCDAVSAYFAGPVKPADVVWTFSG
VRPLYDDGASEAKAATRDYVFELDTPGGAPLLSIYGGKITTYRRLSEEALEKLAPYLKGKTAKEGWTAHQPLPGGDFPVD
GAPALITELTRDYPFLSAAHAHRLVHAYGTRARDLLGAARSMADLGCDFGATLTEAEVRYLINREWACSADDIVWRRSKL
GLRLPPSALAAIDQWIAAFRASEKPQQHAGGRA
>Mature_513_residues
MDRVFDLAIIGGGINGCGIARDAAGRGNSVFLCEMNDLASGTSSWSTKLIHGGLRYLEYFEFRLVREALIERERLWQIAP
HIIGPLRFVLPHHSGLRPAWRLRLGLFLYDYIGGRRLLPPTRSVDLAHDEVGKPLIPGRFTRGFEYSDCFVDDARLVVLT
ARDAAERGAEIRTRTRAAQVRQSGGIWEVTLEDTQSGVRNTIRARALVNAAGPWVEAVLASGAGVNAASKVRLVQGSHIV
VPKLYDHDRAYIFQNADGRIVFAIPYQGDFTLIGTTDRDYDGDPSQVKATPDEISYLCDAVSAYFAGPVKPADVVWTFSG
VRPLYDDGASEAKAATRDYVFELDTPGGAPLLSIYGGKITTYRRLSEEALEKLAPYLKGKTAKEGWTAHQPLPGGDFPVD
GAPALITELTRDYPFLSAAHAHRLVHAYGTRARDLLGAARSMADLGCDFGATLTEAEVRYLINREWACSADDIVWRRSKL
GLRLPPSALAAIDQWIAAFRASEKPQQHAGGRA

Specific function: Conversion Of Glycerol 3-Phosphate To Dihydroxyacetone. Uses Molecular Oxygen Or Nitrate As Electron Acceptor. [C]

COG id: COG0578

COG function: function code C; Glycerol-3-phosphate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI285002233, Length=513, Percent_Identity=31.9688109161793, Blast_Score=197, Evalue=2e-50,
Organism=Homo sapiens, GI285002231, Length=513, Percent_Identity=31.9688109161793, Blast_Score=197, Evalue=2e-50,
Organism=Escherichia coli, GI2367226, Length=472, Percent_Identity=47.8813559322034, Blast_Score=445, Evalue=1e-126,
Organism=Caenorhabditis elegans, GI17509253, Length=506, Percent_Identity=30.6324110671937, Blast_Score=182, Evalue=3e-46,
Organism=Caenorhabditis elegans, GI115534726, Length=516, Percent_Identity=28.4883720930233, Blast_Score=152, Evalue=5e-37,
Organism=Saccharomyces cerevisiae, GI6322036, Length=560, Percent_Identity=28.3928571428571, Blast_Score=160, Evalue=6e-40,
Organism=Drosophila melanogaster, GI161077125, Length=513, Percent_Identity=31.1890838206628, Blast_Score=174, Evalue=2e-43,
Organism=Drosophila melanogaster, GI24653942, Length=513, Percent_Identity=31.1890838206628, Blast_Score=174, Evalue=2e-43,
Organism=Drosophila melanogaster, GI24653944, Length=513, Percent_Identity=31.1890838206628, Blast_Score=174, Evalue=2e-43,
Organism=Drosophila melanogaster, GI20130025, Length=513, Percent_Identity=31.1890838206628, Blast_Score=174, Evalue=2e-43,
Organism=Drosophila melanogaster, GI24586295, Length=510, Percent_Identity=30, Blast_Score=141, Evalue=8e-34,
Organism=Drosophila melanogaster, GI19921278, Length=493, Percent_Identity=24.9492900608519, Blast_Score=97, Evalue=3e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006076
- InterPro:   IPR000447 [H]

Pfam domain/function: PF01266 DAO [H]

EC number: =1.1.5.3 [H]

Molecular weight: Translated: 56250; Mature: 56250

Theoretical pI: Translated: 7.62; Mature: 7.62

Prosite motif: PS00977 FAD_G3PDH_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
0.6 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDRVFDLAIIGGGINGCGIARDAAGRGNSVFLCEMNDLASGTSSWSTKLIHGGLRYLEYF
CCCEEEEEEECCCCCCCCCCCCCCCCCCEEEEEECHHHCCCCCHHHHHHHHHHHHHHHHH
EFRLVREALIERERLWQIAPHIIGPLRFVLPHHSGLRPAWRLRLGLFLYDYIGGRRLLPP
HHHHHHHHHHHHHHHHHHHHHHHCCHHHCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCC
TRSVDLAHDEVGKPLIPGRFTRGFEYSDCFVDDARLVVLTARDAAERGAEIRTRTRAAQV
CCCCCCCHHHCCCCCCCCCCCCCCCCCCEEECCCEEEEEEECCHHHCCCHHHHHHHHHHH
RQSGGIWEVTLEDTQSGVRNTIRARALVNAAGPWVEAVLASGAGVNAASKVRLVQGSHIV
HHCCCEEEEEEHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCHHEEEEEECCEEE
VPKLYDHDRAYIFQNADGRIVFAIPYQGDFTLIGTTDRDYDGDPSQVKATPDEISYLCDA
ECEEECCCCEEEEECCCCEEEEEEECCCCEEEEECCCCCCCCCCCCEECCHHHHHHHHHH
VSAYFAGPVKPADVVWTFSGVRPLYDDGASEAKAATRDYVFELDTPGGAPLLSIYGGKIT
HHHHHCCCCCCCEEEEEECCCCCHHCCCCHHHHHHCCCEEEEECCCCCCCEEEEECCCCH
TYRRLSEEALEKLAPYLKGKTAKEGWTAHQPLPGGDFPVDGAPALITELTRDYPFLSAAH
HHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCHHHHH
AHRLVHAYGTRARDLLGAARSMADLGCDFGATLTEAEVRYLINREWACSADDIVWRRSKL
HHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCCCCHHHHHHHHHC
GLRLPPSALAAIDQWIAAFRASEKPQQHAGGRA
CCCCCHHHHHHHHHHHHHHHCCCCCHHHCCCCC
>Mature Secondary Structure
MDRVFDLAIIGGGINGCGIARDAAGRGNSVFLCEMNDLASGTSSWSTKLIHGGLRYLEYF
CCCEEEEEEECCCCCCCCCCCCCCCCCCEEEEEECHHHCCCCCHHHHHHHHHHHHHHHHH
EFRLVREALIERERLWQIAPHIIGPLRFVLPHHSGLRPAWRLRLGLFLYDYIGGRRLLPP
HHHHHHHHHHHHHHHHHHHHHHHCCHHHCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCC
TRSVDLAHDEVGKPLIPGRFTRGFEYSDCFVDDARLVVLTARDAAERGAEIRTRTRAAQV
CCCCCCCHHHCCCCCCCCCCCCCCCCCCEEECCCEEEEEEECCHHHCCCHHHHHHHHHHH
RQSGGIWEVTLEDTQSGVRNTIRARALVNAAGPWVEAVLASGAGVNAASKVRLVQGSHIV
HHCCCEEEEEEHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCHHEEEEEECCEEE
VPKLYDHDRAYIFQNADGRIVFAIPYQGDFTLIGTTDRDYDGDPSQVKATPDEISYLCDA
ECEEECCCCEEEEECCCCEEEEEEECCCCEEEEECCCCCCCCCCCCEECCHHHHHHHHHH
VSAYFAGPVKPADVVWTFSGVRPLYDDGASEAKAATRDYVFELDTPGGAPLLSIYGGKIT
HHHHHCCCCCCCEEEEEECCCCCHHCCCCHHHHHHCCCEEEEECCCCCCCEEEEECCCCH
TYRRLSEEALEKLAPYLKGKTAKEGWTAHQPLPGGDFPVDGAPALITELTRDYPFLSAAH
HHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCHHHHH
AHRLVHAYGTRARDLLGAARSMADLGCDFGATLTEAEVRYLINREWACSADDIVWRRSKL
HHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCCCCHHHHHHHHHC
GLRLPPSALAAIDQWIAAFRASEKPQQHAGGRA
CCCCCHHHHHHHHHHHHHHHCCCCCHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8157588; 10984043 [H]