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The map label for this gene is clcB [H]

Identifier: 86751172

GI number: 86751172

Start: 4635572

End: 4637380

Strand: Reverse

Name: clcB [H]

Synonym: RPB_4064

Alternate gene names: 86751172

Gene position: 4637380-4635572 (Counterclockwise)

Preceding gene: 86751174

Following gene: 86751168

Centisome position: 86.98

GC content: 67.44

Gene sequence:

>1809_bases
GTGAGCGCTGCATCACGGCCCGATCCAAGGGCGGCCGCGTCGGCGGGGTCTTCGTCGGCGTCGGGCCGTTGGTTGTTCCC
GGCTGGCTTGCGCAACTTCGTCCGCAATCGCGAAATCGGCCTGGTGATCGTGGCGATGGTGATCGGGCTGCTGTCGGGGC
TGTTGGTTGCGACGATCTCGATGCTGAGCGAGCTCGCGCACGCCATCCTGTTCGATATTCCATTCGACACCAAGCTGAGC
GCGTCCGGCGTGATTTCATGGCAGCGGACGCTGCTGGTGCCGATCGCCGGCGCGGTCATTCTGGCGCTGATCGCCATCTT
CTATGCGGGCCGTTTCAAGGGGCAATTGGCGGACGCGATCGAGGCCAATGCGCTGTATGGCGGCCGTGTCTCGATGCGCG
GCAGCCTGCTGATCTCGATTCAGACCCTGCTGTCGAACGGCTTCGGCGCTTCGGTCGGGCTCGAGGCCGGCTATACCCAG
ATCTGCGCGGCCTTCAGCTCGCAAATCGGGCAGCGGCTCGCGGCGCGGCGCGCCGACTTGCGTCTCCTGGTGGCGTGCGG
CGCCGCGGGGGCGATCAGCGCCGCGTTCTCGGCGCCGCTGGCGGGCGCCTTCTTCGCCTTCGAGGTCGTGCTCGGCGCCT
ATACGTCCGCGGCCCTGGTGCCGGTGATCGCCAGCGCGGTGGCGGCGTGGCTGGTGACGCGCCATCTGGCGCATCAGCAG
TTCCTGATGGTGCCGGGCGTGCCGACGCCGGTGTCGGTGGAGATGATCGGCCAGGTCATGGCTGTCGGGATTCTATGTGC
ATTCTTCAGCATCCTGGTGATGCTGGCGGTGGCGTTCGCCGAGCGGACCTTGCAGCGGGTCACCTGGCTGCGCGGCGGGC
TGCGCTTCGTCATCGGGGCGGCCATGCTCGGCTGTCTCGGGCTGCTGACGCCGACCGTGCTCGGCTCCGGCCACGGCGCG
ATGCAGATCCTGCTGGTGAGCAATCCGACCTGGCTGATGCTGGCGACCACGATCCTGCTCAAGACCGCCGCGTCGGCGAT
CTCGCTCGGCGCCGGCTTTCGCGGCGGCCTGTTCTTCGCTTCGCTGATGCTGGGTTCGATGATCGGCCAGCTCTACAGCA
CGGTGCTGAGCGGGCCGTTTCCGGAACTGGCGCTGCAGCCGGGAACGGCGGCCGTCGCCGGGATGGTCGCGCTCGGCACC
GGCGTGCTCGGCGCTCCGTTCAGCATGGTGTGCCTCGCGCTCGAACTCACCGGCGACTTTTCGATCACGGCGGGCGCGGT
TGTCGCGGCGTCGATCAGCGCGATGATCGTGCGCGAATTGTTCGGCTACAGCTTCGCCACCTGGCGCTTTCATTTGCGCG
GCGAAGCCATTCGCGGGCCGCAGGACGTCGGCTGGGTCAGGCAGATCAGCGCGGCGACGTTGATGCGGTCGGATTTCGAA
ACCGCGCAGGCCGGCCTGTCGATCGCCGAGGCGCAGACGCTGTTTCCGCCGGGGCGCATCAAGCAGATCGTGCTGAGGAA
AACCGACGGCTCCTATGGCGGCATCGTGGAAGCGCCCGAACTGCACGGGCATGTCCATGCCGAGGACGAGACGCTCGACA
CGCTGGCGCATCAGCGCGACGAGTTCCTGCTGCCGGACATCACCGTGCGCGACATCGTGACGGCGTTCGACCGCAGCGAA
GCCGACGTGCTGGTGGTGGTGAACAATGCCGAGGAGCGGGTGACGATCGGCCTCGTCAGCGAGGCGCATGTGCTGCGCAC
TTTCGCCACCGAGCTCGAGCGGCGCAATCAGGAAGTGTTCTTTCGCTGA

Upstream 100 bases:

>100_bases
CAGTGACGCCGCGAGGGCTTTCTCGACTGCGCGGGGCCTCGCCCCAACTGGTCGGTGCGGCCGTCGCCGTTGGCAAGGTC
AATTCACCCCGGATCGGCCG

Downstream 100 bases:

>100_bases
TCGGCTCGGCTCAGGGGCGAAGGTCCATGTCGATCCGGACGAAGTCGCCGCGGTAAGTCACTTCGCCGAGATAGATCACG
GTGCGGTCGGCGGCGGTGAA

Product: Cl- channel, voltage gated

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 602; Mature: 601

Protein sequence:

>602_residues
MSAASRPDPRAAASAGSSSASGRWLFPAGLRNFVRNREIGLVIVAMVIGLLSGLLVATISMLSELAHAILFDIPFDTKLS
ASGVISWQRTLLVPIAGAVILALIAIFYAGRFKGQLADAIEANALYGGRVSMRGSLLISIQTLLSNGFGASVGLEAGYTQ
ICAAFSSQIGQRLAARRADLRLLVACGAAGAISAAFSAPLAGAFFAFEVVLGAYTSAALVPVIASAVAAWLVTRHLAHQQ
FLMVPGVPTPVSVEMIGQVMAVGILCAFFSILVMLAVAFAERTLQRVTWLRGGLRFVIGAAMLGCLGLLTPTVLGSGHGA
MQILLVSNPTWLMLATTILLKTAASAISLGAGFRGGLFFASLMLGSMIGQLYSTVLSGPFPELALQPGTAAVAGMVALGT
GVLGAPFSMVCLALELTGDFSITAGAVVAASISAMIVRELFGYSFATWRFHLRGEAIRGPQDVGWVRQISAATLMRSDFE
TAQAGLSIAEAQTLFPPGRIKQIVLRKTDGSYGGIVEAPELHGHVHAEDETLDTLAHQRDEFLLPDITVRDIVTAFDRSE
ADVLVVVNNAEERVTIGLVSEAHVLRTFATELERRNQEVFFR

Sequences:

>Translated_602_residues
MSAASRPDPRAAASAGSSSASGRWLFPAGLRNFVRNREIGLVIVAMVIGLLSGLLVATISMLSELAHAILFDIPFDTKLS
ASGVISWQRTLLVPIAGAVILALIAIFYAGRFKGQLADAIEANALYGGRVSMRGSLLISIQTLLSNGFGASVGLEAGYTQ
ICAAFSSQIGQRLAARRADLRLLVACGAAGAISAAFSAPLAGAFFAFEVVLGAYTSAALVPVIASAVAAWLVTRHLAHQQ
FLMVPGVPTPVSVEMIGQVMAVGILCAFFSILVMLAVAFAERTLQRVTWLRGGLRFVIGAAMLGCLGLLTPTVLGSGHGA
MQILLVSNPTWLMLATTILLKTAASAISLGAGFRGGLFFASLMLGSMIGQLYSTVLSGPFPELALQPGTAAVAGMVALGT
GVLGAPFSMVCLALELTGDFSITAGAVVAASISAMIVRELFGYSFATWRFHLRGEAIRGPQDVGWVRQISAATLMRSDFE
TAQAGLSIAEAQTLFPPGRIKQIVLRKTDGSYGGIVEAPELHGHVHAEDETLDTLAHQRDEFLLPDITVRDIVTAFDRSE
ADVLVVVNNAEERVTIGLVSEAHVLRTFATELERRNQEVFFR
>Mature_601_residues
SAASRPDPRAAASAGSSSASGRWLFPAGLRNFVRNREIGLVIVAMVIGLLSGLLVATISMLSELAHAILFDIPFDTKLSA
SGVISWQRTLLVPIAGAVILALIAIFYAGRFKGQLADAIEANALYGGRVSMRGSLLISIQTLLSNGFGASVGLEAGYTQI
CAAFSSQIGQRLAARRADLRLLVACGAAGAISAAFSAPLAGAFFAFEVVLGAYTSAALVPVIASAVAAWLVTRHLAHQQF
LMVPGVPTPVSVEMIGQVMAVGILCAFFSILVMLAVAFAERTLQRVTWLRGGLRFVIGAAMLGCLGLLTPTVLGSGHGAM
QILLVSNPTWLMLATTILLKTAASAISLGAGFRGGLFFASLMLGSMIGQLYSTVLSGPFPELALQPGTAAVAGMVALGTG
VLGAPFSMVCLALELTGDFSITAGAVVAASISAMIVRELFGYSFATWRFHLRGEAIRGPQDVGWVRQISAATLMRSDFET
AQAGLSIAEAQTLFPPGRIKQIVLRKTDGSYGGIVEAPELHGHVHAEDETLDTLAHQRDEFLLPDITVRDIVTAFDRSEA
DVLVVVNNAEERVTIGLVSEAHVLRTFATELERRNQEVFFR

Specific function: Probably acts as an electrical shunt for an outwardly- directed proton pump that is linked to amino acid decarboxylation, as part of the extreme acid resistance (XAR) response [H]

COG id: COG0038

COG function: function code P; Chloride channel protein EriC

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the chloride channel (TC 2.A.49) family. ClcB subfamily [H]

Homologues:

Organism=Escherichia coli, GI87081943, Length=408, Percent_Identity=29.4117647058824, Blast_Score=98, Evalue=2e-21,
Organism=Escherichia coli, GI1786350, Length=236, Percent_Identity=27.1186440677966, Blast_Score=64, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014743
- InterPro:   IPR001807 [H]

Pfam domain/function: PF00654 Voltage_CLC [H]

EC number: NA

Molecular weight: Translated: 63345; Mature: 63214

Theoretical pI: Translated: 7.62; Mature: 7.62

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSAASRPDPRAAASAGSSSASGRWLFPAGLRNFVRNREIGLVIVAMVIGLLSGLLVATIS
CCCCCCCCCCHHHCCCCCCCCCCEEEHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHH
MLSELAHAILFDIPFDTKLSASGVISWQRTLLVPIAGAVILALIAIFYAGRFKGQLADAI
HHHHHHHHHHEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHH
EANALYGGRVSMRGSLLISIQTLLSNGFGASVGLEAGYTQICAAFSSQIGQRLAARRADL
HHCCEECCCEEECCHHEEEHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCE
RLLVACGAAGAISAAFSAPLAGAFFAFEVVLGAYTSAALVPVIASAVAAWLVTRHLAHQQ
EEEEEECCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
FLMVPGVPTPVSVEMIGQVMAVGILCAFFSILVMLAVAFAERTLQRVTWLRGGLRFVIGA
EEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AMLGCLGLLTPTVLGSGHGAMQILLVSNPTWLMLATTILLKTAASAISLGAGFRGGLFFA
HHHHHHHHHHHHHHCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHH
SLMLGSMIGQLYSTVLSGPFPELALQPGTAAVAGMVALGTGVLGAPFSMVCLALELTGDF
HHHHHHHHHHHHHHHHCCCCCHHEECCCHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCCC
SITAGAVVAASISAMIVRELFGYSFATWRFHLRGEAIRGPQDVGWVRQISAATLMRSDFE
CCHHHHHHHHHHHHHHHHHHHCCCEEEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHH
TAQAGLSIAEAQTLFPPGRIKQIVLRKTDGSYGGIVEAPELHGHVHAEDETLDTLAHQRD
HHHHCCHHHHHHHCCCCHHHHEEEEEECCCCCCCCCCCCHHCCCCCCCHHHHHHHHHCCC
EFLLPDITVRDIVTAFDRSEADVLVVVNNAEERVTIGLVSEAHVLRTFATELERRNQEVF
CCCCCCCHHHHHHHHHCCCCCCEEEEEECCCCEEEEEEHHHHHHHHHHHHHHHHCCCCCC
FR
CC
>Mature Secondary Structure 
SAASRPDPRAAASAGSSSASGRWLFPAGLRNFVRNREIGLVIVAMVIGLLSGLLVATIS
CCCCCCCCCHHHCCCCCCCCCCEEEHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHH
MLSELAHAILFDIPFDTKLSASGVISWQRTLLVPIAGAVILALIAIFYAGRFKGQLADAI
HHHHHHHHHHEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHH
EANALYGGRVSMRGSLLISIQTLLSNGFGASVGLEAGYTQICAAFSSQIGQRLAARRADL
HHCCEECCCEEECCHHEEEHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCE
RLLVACGAAGAISAAFSAPLAGAFFAFEVVLGAYTSAALVPVIASAVAAWLVTRHLAHQQ
EEEEEECCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
FLMVPGVPTPVSVEMIGQVMAVGILCAFFSILVMLAVAFAERTLQRVTWLRGGLRFVIGA
EEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AMLGCLGLLTPTVLGSGHGAMQILLVSNPTWLMLATTILLKTAASAISLGAGFRGGLFFA
HHHHHHHHHHHHHHCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHH
SLMLGSMIGQLYSTVLSGPFPELALQPGTAAVAGMVALGTGVLGAPFSMVCLALELTGDF
HHHHHHHHHHHHHHHHCCCCCHHEECCCHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCCC
SITAGAVVAASISAMIVRELFGYSFATWRFHLRGEAIRGPQDVGWVRQISAATLMRSDFE
CCHHHHHHHHHHHHHHHHHHHCCCEEEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHH
TAQAGLSIAEAQTLFPPGRIKQIVLRKTDGSYGGIVEAPELHGHVHAEDETLDTLAHQRD
HHHHCCHHHHHHHCCCCHHHHEEEEEECCCCCCCCCCCCHHCCCCCCCHHHHHHHHHCCC
EFLLPDITVRDIVTAFDRSEADVLVVVNNAEERVTIGLVSEAHVLRTFATELERRNQEVF
CCCCCCCHHHHHHHHHCCCCCCEEEEEECCCCEEEEEEHHHHHHHHHHHHHHHHCCCCCC
FR
CC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA