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The map label for this gene is ptrB [H]

Identifier: 86751067

GI number: 86751067

Start: 4519260

End: 4521386

Strand: Direct

Name: ptrB [H]

Synonym: RPB_3959

Alternate gene names: 86751067

Gene position: 4519260-4521386 (Clockwise)

Preceding gene: 86751061

Following gene: 86751068

Centisome position: 84.76

GC content: 66.67

Gene sequence:

>2127_bases
ATGCAACGAGACCCGCTCATGACCCTGTCCCCGCCCCGCGACGCCACGCCTCCCGTCGCGCCGCGCCGTCCGCACGCCTT
CACCACCCACGGCATCACCATCAACGACGACTATGCCTGGCTGAAGGACCCGAACTGGCAGGAGGTGCTGCGCGATCCGG
CGCTGCTCGATCCCGATATCCGCGCCTATCTCGAAGCCGAGAACGGCTACACCGACAGCGTGCTCGGCCACACCGAGGCG
TTGCAGAAGACGCTGGTTGCGGAAATGCGCGGGCGGATCAAGGAAGACGATTCCAGCGTGCCGCAGCCGGACGGGCCCTA
CGCTTACTTGCGCAAATTCCGCGAAGGCGGCCAGCATCCGCTGTATGGCCGCACGCCGCGCGACGGCGGCGAACTCGACA
TCATCCTCGACGGCGACGAACTGGCGAAGGGCACCGAGTACTTCCAGTTCGGCGGACGGCGGCATTCGCTCGACCACAAG
CTGGAAGCCTGGAGCGCTGACGCCAAGGGCTCGGAATACTACACCATCCGCGTGCGCGACTGGACGACGAAGCAGGATTT
GCCCGACCTCGTCGAGGAGACCGACGGCGGCGTGGTCTGGACCGCGGACTCGAGCGCGTTCTTCTACGTCAAGCTCGACG
ACAATCATCGGCCGATGCAGATCTGGCTGCACAAGCTCGGCACCGCGCAGGCCGACGACCTGCTGGTGTACGAGGAGAAA
GACGCCGGCTGGTTCACCCACATCCACGAGAGCAGCAGCGGACGGTTCTGCGTGATCGCCGGCGGCGACCACGAGACGTC
GGAGCAGCGGCTGATCGACGTCTCCGATCCGACCGCGCCGCCGCGGCTCGTCGCCGCGCGCGAACTCGGCGTGCAATATT
CGCTCGCAGATCGCGGCGACGAGCTGTTCATCCTCACCAATGCGGACGGCGCGATCGACTTCAAGATCGTCACCGCGCCG
CTGGCTTCGCCTGTGCGCGACAATTGGCGCGATCTGATCCCGCATCGCGAAGGCATCTATATCATCGACTTCGACCTGTT
CTCCGGCCACATGATGCGGCTGGAGCGCGCCAACGCGCTGCCGTCGGTGACGATCCGCGATCTCGCGAGCGGCGATGAGC
ATGCCATCGCCTTCGACGAGGCGGCCTACTCGCTGTCCGCCTCCGGCGGCTGGGAATTCGACACCACGGTGATGCGGTTC
TCCTACTCGTCGATGACGACGCCGTCGGAAGTCTACGATTACGACATGGCGACGCGCGAGCGGAGCTTGCGCAAGCGCCA
GGAAATTCCCTCGGGCCAAAATCCGGCAGACTACGTCACCACCCGGATCATGGCGAAGGCCGACGACGGCGCCGAGGTGC
CGGTGTCGCTGCTGCATCGCAAGGGGCTCGCGCTCGACGGCGCGGCGCCGCTGCTTCTGTACGGCTACGGCTCCTACGGC
CACGCGATGCCGGCGGGCTTCTCCGCCAACGCGCTGTCGCTGGTCGATCGCGGCTTCGTTTACGCGATCGCGCATATCCG
CGGCGGCGCCGACAAGGGCTGGGGCTGGTATCTCGACGGCAAGCGCGAGAAGAAGACCAACTCGTTCGACGATTTCGCCG
CCTGCGCGCAGGCGTTGATCGACGCCAAGTACACGTCGGCGAAACGCATTGTCGCCCATGGCGGCAGTGCCGGCGGCATG
CTGATGGGCGCGGTCGCCAACCGCTCGGGCGAGTTGTTCGCCGGCATCGTCGCCGAAGTGCCGTTCGTCGACGTGCTCAA
CACCATGCTCGACGATACGCTGCCGCTGACGCCGCCGGAATGGCCTGAATGGGGAAATCCGATCAGCAGCGAAGCCGACT
TCAAAACCATCCTGTCCTACTCGCCCTACGACAACGTCGCGGCGACGACCTATCCGGCCATCCTCGCGATGGGCGGCCTC
ACCGATCCGCGCGTCACCTATTGGGAGCCGGCGAAATGGGTGGCGCGGCTGCGCGCGACCATGACCGGCGGCGGCCCCGT
GCTGCTCCGCATCAACATGGGCGCCGGCCACGGCGGCGCGTCCGGCCGGTTCAGCCGGCTCGACGAGGTCGCGATCGTCT
ACGCCTTCGCCTTGTGGGCGGTCGGCCTCGCGGATTCCGCTGCCTGA

Upstream 100 bases:

>100_bases
ACATGCTGTCTCTGGCGGAAGCCGGAACCGGCCGCGGCCTATCGACATCAATCCGGCGCGCGCCGCAAGCGCCAAACTCT
GCTAAGCCAACCGCATCCGC

Downstream 100 bases:

>100_bases
ACTTCGCCACCAGTTTGCCGCAACCCTCCTTCAGCCGCAGAGATGCTCATGGCCGCTCCAAAACCGCCCGGATTCGAGAC
ACTTAGCCTGCACGCCGGGC

Product: oligopeptidase B

Products: NA

Alternate protein names: Oligopeptidase B; Protease II [H]

Number of amino acids: Translated: 708; Mature: 708

Protein sequence:

>708_residues
MQRDPLMTLSPPRDATPPVAPRRPHAFTTHGITINDDYAWLKDPNWQEVLRDPALLDPDIRAYLEAENGYTDSVLGHTEA
LQKTLVAEMRGRIKEDDSSVPQPDGPYAYLRKFREGGQHPLYGRTPRDGGELDIILDGDELAKGTEYFQFGGRRHSLDHK
LEAWSADAKGSEYYTIRVRDWTTKQDLPDLVEETDGGVVWTADSSAFFYVKLDDNHRPMQIWLHKLGTAQADDLLVYEEK
DAGWFTHIHESSSGRFCVIAGGDHETSEQRLIDVSDPTAPPRLVAARELGVQYSLADRGDELFILTNADGAIDFKIVTAP
LASPVRDNWRDLIPHREGIYIIDFDLFSGHMMRLERANALPSVTIRDLASGDEHAIAFDEAAYSLSASGGWEFDTTVMRF
SYSSMTTPSEVYDYDMATRERSLRKRQEIPSGQNPADYVTTRIMAKADDGAEVPVSLLHRKGLALDGAAPLLLYGYGSYG
HAMPAGFSANALSLVDRGFVYAIAHIRGGADKGWGWYLDGKREKKTNSFDDFAACAQALIDAKYTSAKRIVAHGGSAGGM
LMGAVANRSGELFAGIVAEVPFVDVLNTMLDDTLPLTPPEWPEWGNPISSEADFKTILSYSPYDNVAATTYPAILAMGGL
TDPRVTYWEPAKWVARLRATMTGGGPVLLRINMGAGHGGASGRFSRLDEVAIVYAFALWAVGLADSAA

Sequences:

>Translated_708_residues
MQRDPLMTLSPPRDATPPVAPRRPHAFTTHGITINDDYAWLKDPNWQEVLRDPALLDPDIRAYLEAENGYTDSVLGHTEA
LQKTLVAEMRGRIKEDDSSVPQPDGPYAYLRKFREGGQHPLYGRTPRDGGELDIILDGDELAKGTEYFQFGGRRHSLDHK
LEAWSADAKGSEYYTIRVRDWTTKQDLPDLVEETDGGVVWTADSSAFFYVKLDDNHRPMQIWLHKLGTAQADDLLVYEEK
DAGWFTHIHESSSGRFCVIAGGDHETSEQRLIDVSDPTAPPRLVAARELGVQYSLADRGDELFILTNADGAIDFKIVTAP
LASPVRDNWRDLIPHREGIYIIDFDLFSGHMMRLERANALPSVTIRDLASGDEHAIAFDEAAYSLSASGGWEFDTTVMRF
SYSSMTTPSEVYDYDMATRERSLRKRQEIPSGQNPADYVTTRIMAKADDGAEVPVSLLHRKGLALDGAAPLLLYGYGSYG
HAMPAGFSANALSLVDRGFVYAIAHIRGGADKGWGWYLDGKREKKTNSFDDFAACAQALIDAKYTSAKRIVAHGGSAGGM
LMGAVANRSGELFAGIVAEVPFVDVLNTMLDDTLPLTPPEWPEWGNPISSEADFKTILSYSPYDNVAATTYPAILAMGGL
TDPRVTYWEPAKWVARLRATMTGGGPVLLRINMGAGHGGASGRFSRLDEVAIVYAFALWAVGLADSAA
>Mature_708_residues
MQRDPLMTLSPPRDATPPVAPRRPHAFTTHGITINDDYAWLKDPNWQEVLRDPALLDPDIRAYLEAENGYTDSVLGHTEA
LQKTLVAEMRGRIKEDDSSVPQPDGPYAYLRKFREGGQHPLYGRTPRDGGELDIILDGDELAKGTEYFQFGGRRHSLDHK
LEAWSADAKGSEYYTIRVRDWTTKQDLPDLVEETDGGVVWTADSSAFFYVKLDDNHRPMQIWLHKLGTAQADDLLVYEEK
DAGWFTHIHESSSGRFCVIAGGDHETSEQRLIDVSDPTAPPRLVAARELGVQYSLADRGDELFILTNADGAIDFKIVTAP
LASPVRDNWRDLIPHREGIYIIDFDLFSGHMMRLERANALPSVTIRDLASGDEHAIAFDEAAYSLSASGGWEFDTTVMRF
SYSSMTTPSEVYDYDMATRERSLRKRQEIPSGQNPADYVTTRIMAKADDGAEVPVSLLHRKGLALDGAAPLLLYGYGSYG
HAMPAGFSANALSLVDRGFVYAIAHIRGGADKGWGWYLDGKREKKTNSFDDFAACAQALIDAKYTSAKRIVAHGGSAGGM
LMGAVANRSGELFAGIVAEVPFVDVLNTMLDDTLPLTPPEWPEWGNPISSEADFKTILSYSPYDNVAATTYPAILAMGGL
TDPRVTYWEPAKWVARLRATMTGGGPVLLRINMGAGHGGASGRFSRLDEVAIVYAFALWAVGLADSAA

Specific function: Cleaves peptide bonds on the C-terminal side of lysyl and argininyl residues [H]

COG id: COG1770

COG function: function code E; Protease II

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S9A family [H]

Homologues:

Organism=Homo sapiens, GI41349456, Length=709, Percent_Identity=26.0930888575458, Blast_Score=207, Evalue=2e-53,
Organism=Homo sapiens, GI284172438, Length=492, Percent_Identity=31.5040650406504, Blast_Score=207, Evalue=2e-53,
Organism=Homo sapiens, GI284172431, Length=492, Percent_Identity=31.5040650406504, Blast_Score=207, Evalue=2e-53,
Organism=Homo sapiens, GI284172420, Length=492, Percent_Identity=31.5040650406504, Blast_Score=207, Evalue=2e-53,
Organism=Homo sapiens, GI284172413, Length=492, Percent_Identity=31.5040650406504, Blast_Score=207, Evalue=2e-53,
Organism=Homo sapiens, GI70778815, Length=492, Percent_Identity=31.5040650406504, Blast_Score=207, Evalue=2e-53,
Organism=Homo sapiens, GI108860692, Length=485, Percent_Identity=29.2783505154639, Blast_Score=169, Evalue=1e-41,
Organism=Homo sapiens, GI108860686, Length=288, Percent_Identity=34.375, Blast_Score=144, Evalue=4e-34,
Organism=Escherichia coli, GI1788150, Length=685, Percent_Identity=38.978102189781, Blast_Score=461, Evalue=1e-131,
Organism=Drosophila melanogaster, GI24583414, Length=710, Percent_Identity=26.3380281690141, Blast_Score=205, Evalue=1e-52,
Organism=Drosophila melanogaster, GI221510989, Length=712, Percent_Identity=24.1573033707865, Blast_Score=177, Evalue=3e-44,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002471
- InterPro:   IPR001375
- InterPro:   IPR002470
- InterPro:   IPR004106 [H]

Pfam domain/function: PF00326 Peptidase_S9; PF02897 Peptidase_S9_N [H]

EC number: =3.4.21.83 [H]

Molecular weight: Translated: 77882; Mature: 77882

Theoretical pI: Translated: 4.80; Mature: 4.80

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQRDPLMTLSPPRDATPPVAPRRPHAFTTHGITINDDYAWLKDPNWQEVLRDPALLDPDI
CCCCCCEEECCCCCCCCCCCCCCCCCEEECCEEECCCCCCCCCCCHHHHHCCCCCCCCCC
RAYLEAENGYTDSVLGHTEALQKTLVAEMRGRIKEDDSSVPQPDGPYAYLRKFREGGQHP
EEEEECCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHCCCCC
LYGRTPRDGGELDIILDGDELAKGTEYFQFGGRRHSLDHKLEAWSADAKGSEYYTIRVRD
CCCCCCCCCCCEEEEECCHHHCCCCHHHHCCCCCCCCCHHHHHCCCCCCCCEEEEEEEEC
WTTKQDLPDLVEETDGGVVWTADSSAFFYVKLDDNHRPMQIWLHKLGTAQADDLLVYEEK
CCCCCCCHHHHHHCCCCEEEEECCCEEEEEEECCCCCHHHHHHHHHCCCCCCCEEEEEEC
DAGWFTHIHESSSGRFCVIAGGDHETSEQRLIDVSDPTAPPRLVAARELGVQYSLADRGD
CCCEEEEEEECCCCCEEEEECCCCCCCCCEEEECCCCCCCCHHHHHHHHCCEEEECCCCC
ELFILTNADGAIDFKIVTAPLASPVRDNWRDLIPHREGIYIIDFDLFSGHMMRLERANAL
EEEEEECCCCEEEEEEEECCCCCCHHHHHHHHCCCCCCEEEEEECCCCCHHHHHHHHCCC
PSVTIRDLASGDEHAIAFDEAAYSLSASGGWEFDTTVMRFSYSSMTTPSEVYDYDMATRE
CCEEHHHHCCCCCCEEEECCHHEEEECCCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHH
RSLRKRQEIPSGQNPADYVTTRIMAKADDGAEVPVSLLHRKGLALDGAAPLLLYGYGSYG
HHHHHHHCCCCCCCCHHHHHHEEEEECCCCCCCCHHHHHHCCCEECCCCCEEEEECCCCC
HAMPAGFSANALSLVDRGFVYAIAHIRGGADKGWGWYLDGKREKKTNSFDDFAACAQALI
CCCCCCCCCCHHHHHHCCCEEEEEECCCCCCCCCEEEECCCCCCCCCCHHHHHHHHHHHH
DAKYTSAKRIVAHGGSAGGMLMGAVANRSGELFAGIVAEVPFVDVLNTMLDDTLPLTPPE
HHHHCCCCCCEECCCCCCCEEEEEHHCCCCCEEEHHHHHCCHHHHHHHHHHCCCCCCCCC
WPEWGNPISSEADFKTILSYSPYDNVAATTYPAILAMGGLTDPRVTYWEPAKWVARLRAT
CCCCCCCCCCCCCHHHHEECCCCCCCHHHHHHHHHHCCCCCCCCEEEECHHHHHHHHHHH
MTGGGPVLLRINMGAGHGGASGRFSRLDEVAIVYAFALWAVGLADSAA
CCCCCEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MQRDPLMTLSPPRDATPPVAPRRPHAFTTHGITINDDYAWLKDPNWQEVLRDPALLDPDI
CCCCCCEEECCCCCCCCCCCCCCCCCEEECCEEECCCCCCCCCCCHHHHHCCCCCCCCCC
RAYLEAENGYTDSVLGHTEALQKTLVAEMRGRIKEDDSSVPQPDGPYAYLRKFREGGQHP
EEEEECCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHCCCCC
LYGRTPRDGGELDIILDGDELAKGTEYFQFGGRRHSLDHKLEAWSADAKGSEYYTIRVRD
CCCCCCCCCCCEEEEECCHHHCCCCHHHHCCCCCCCCCHHHHHCCCCCCCCEEEEEEEEC
WTTKQDLPDLVEETDGGVVWTADSSAFFYVKLDDNHRPMQIWLHKLGTAQADDLLVYEEK
CCCCCCCHHHHHHCCCCEEEEECCCEEEEEEECCCCCHHHHHHHHHCCCCCCCEEEEEEC
DAGWFTHIHESSSGRFCVIAGGDHETSEQRLIDVSDPTAPPRLVAARELGVQYSLADRGD
CCCEEEEEEECCCCCEEEEECCCCCCCCCEEEECCCCCCCCHHHHHHHHCCEEEECCCCC
ELFILTNADGAIDFKIVTAPLASPVRDNWRDLIPHREGIYIIDFDLFSGHMMRLERANAL
EEEEEECCCCEEEEEEEECCCCCCHHHHHHHHCCCCCCEEEEEECCCCCHHHHHHHHCCC
PSVTIRDLASGDEHAIAFDEAAYSLSASGGWEFDTTVMRFSYSSMTTPSEVYDYDMATRE
CCEEHHHHCCCCCCEEEECCHHEEEECCCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHH
RSLRKRQEIPSGQNPADYVTTRIMAKADDGAEVPVSLLHRKGLALDGAAPLLLYGYGSYG
HHHHHHHCCCCCCCCHHHHHHEEEEECCCCCCCCHHHHHHCCCEECCCCCEEEEECCCCC
HAMPAGFSANALSLVDRGFVYAIAHIRGGADKGWGWYLDGKREKKTNSFDDFAACAQALI
CCCCCCCCCCHHHHHHCCCEEEEEECCCCCCCCCEEEECCCCCCCCCCHHHHHHHHHHHH
DAKYTSAKRIVAHGGSAGGMLMGAVANRSGELFAGIVAEVPFVDVLNTMLDDTLPLTPPE
HHHHCCCCCCEECCCCCCCEEEEEHHCCCCCEEEHHHHHCCHHHHHHHHHHCCCCCCCCC
WPEWGNPISSEADFKTILSYSPYDNVAATTYPAILAMGGLTDPRVTYWEPAKWVARLRAT
CCCCCCCCCCCCCHHHHEECCCCCCCHHHHHHHHHHCCCCCCCCEEEECHHHHHHHHHHH
MTGGGPVLLRINMGAGHGGASGRFSRLDEVAIVYAFALWAVGLADSAA
CCCCCEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1769955; 9097040; 9278503 [H]