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The map label for this gene is putA [H]

Identifier: 86751054

GI number: 86751054

Start: 4503337

End: 4506348

Strand: Direct

Name: putA [H]

Synonym: RPB_3946

Alternate gene names: 86751054

Gene position: 4503337-4506348 (Clockwise)

Preceding gene: 86751052

Following gene: 86751055

Centisome position: 84.46

GC content: 70.82

Gene sequence:

>3012_bases
ATGCCGCCTGATTCGCCGCATCCGGAATTCGACGCTGCCTACGCGCCCGACGACGCCACGCTCGCGGCGGCGCTGATCGC
GGTGATGCCGCGCGACCCCGCGCGCGAGGCGCCGATCGACACGACCGCCACCGGACTGATCGCAGCGATCCGTGCCGGCG
ATCATCATCTCGGCAGCGTCGAGGCGATGCTGCGCGAATACGCGCTATCCAGCAAAGAGGGGCTTGCGCTGATGGTGCTG
GCCGAGGCGCTGCTGCGGGTGCCGGACGCGGCGACCGCCGACGCCTTCATCGAGGACCGGCTGGGCCAGGGCGATTTCGC
GCATCACCGCATCAAGTCCGATGCGCTGCTGGTCAACGCCTCGGCCTGGGCGCTCGGCCTGTCGGCGCGCGTGGTGCATG
CCGGCGACACGCCGCAAAGCACGCTGGCAGCGCTGGCGAAGCGGATCGGCGCGCCGGCGGTGCGCGCGGCGACGCGGCAG
GCGATGCGGCTGCTCGGCAATCATTTCGTGCTCGGCGAGACCATCGACGATGCGCTCGCCCGCGCGCAGGCGGATGCCGC
CGATGGCGTGCGCTATTCCTACGACATGCTTGGCGAAGGTGCGCGCACCCGGGCCGACGCCGAGCGCTACTTCGCGTCCT
ACGCGCAGGCGATCGACGCGATCGGCCGCGCCGCCGGCAACGCGCGACTGCCGGCGCGGCCGGGCATCTCGGTGAAACTC
TCGGCGCTGCATCCACGCTTCGAGGCGGTGAGCCGCGACCGCGTGCTGCGCGAGCTGACGCCGCGCCTGATCGAGCTGGC
GCGCAAAGCCAAGGACCACGACCTCGGCTTCACCGTCGACGCCGAGGAGGCCGACCGGCTCGAACTCTCGCTCGAGGTGT
TCGCCGCCTGCCTCGCCGATCCTTCGCTCAAAGGCTGGGACGGCTACGGCCTCGCGGTGCAGGCCTATCAGAAACGCGCA
TCCGCGGTGATCGACTACGTCGATGCGCTGGCGCAGCGACACGATCGCCGGCTGATGCTGCGGCTGGTGAAGGGCGCCTA
TTGGGACACCGAGATCAAGCGCGCGCAGGAGCGCGGCCTTGCCGACTATCCGGTGTTCAGCCGCAAGGCGATGACCGACC
TCAACTACCTGCATTGCGTGCAGAAACTACTCGGGCTGCGGCAACGGATCTTCCCGCAATTCGCCAGCCACAACGCGCTG
ACGGTCGCGACCGTCCTCGACCTCGCCGGCGACAGCGACGGCTACGAATTCCAGCGGCTGCACGGCATGGGCGAGGCGCT
GTATGCGCGGCTGCGCGCCGAGCATCCCGAGCTCACCTGCCGGATCTACGCCCCGGTCGGCGGCCATCGCGATCTGCTCG
CCTATCTGGTGCGGCGGCTGCTGGAGAACGGCGCCAATTCGTCGTTCGTCGCGCAGGCCGGCGACGATACCGTGCCGGTA
GAGGAGTTGCTGCGACGGCCGGAGGCGATCATCGGGACGCCCGACAACGCCCGCCATCCGCACATCCCGCTGCCGCGAGA
CTTGTATCGGCCGCAGCGCGAAAACTCGCGCGGCGTCGAATTCGGCGACCGCGCCGCGCTGCGACGGCTGCTCAGTGAGA
TCGACGCCGCGCGCCGGCCGCTGCCGCGCGTCACTCCCGTAACGCCGGAGGATGCGGCGGCGGCGGCGGTGGCCGCCGCG
CGCGATGGCTTCGCCGCATGGAGCCGCACGCCTGCCGAGACCCGCGCCGCCGCGCTGGAGCGCGCCGCTGATCTGTTGGA
GCAGCGCCGCGCGAACTTCGTCGCGCTGCTGCAGGACGAAGCCGGCAAGACGCTCGACGACTGCATCTCCGAGGTCCGCG
AAGCGATCGATTATTGCCGCTACTACGCGGCCGAAGGTCGCCGGCTATTCGGCGACGGCGTCGCGCTGCCCGGCCCGACC
GGCGAGCGCAACAGTCTGCGGCTGCGTGGCCGCGGCGTCTTCGTCGCGATCTCGCCGTGGAATTTTCCGCTGGCGATTTT
CCTCGGCCAGATCACCGCGGCGCTGATGGCCGGCAACGCCGTGATCGCCAAGCCGGCGGAGCAGACGCCGGTGATCGGCG
ACGCCGCCGTGGGGCTTTTGCACGAGGCCGGCGTGCCGCGCGCGGCGCTGCAACTCGTGCAAGGCGACGGCGCGATCGGC
GCGGCGCTGGTGGCGCATCGCGACGTCGCCGGGGTCGTCTTCACCGGCTCGACAGACGTGGCGCGCGCGATCAACCGCGC
GCTCGCCGCGAAGGACGGCCCGATCGTGCCCCTGATCGCCGAGACCGGCGGCATCAATACGATGATCGTCGACGCCACCG
CGCTGCCCGAGCAGGTCGCCGACGACGTCGTGACCTCGGCGTTCCGCTCCGCCGGCCAGCGCTGCTCGGCGCTGCGGCTG
TTGTTCGTGCAGGACGACGTCGCCGAGAGGATGATCGAGATGATCGCCGGCAGCGCCCGCGAATTGAAGCTCGGCGACCC
GCGCGATCCGGCGACGCATCTCGGCCCGGTGATCGACGCCGAGGCCAAGGTCAGGCTCGACGCGCATATTGCGGCGATGA
CGCGCGAGGCGCGGCTGCATTTCGCAGGCGCCGCGCCGTCCACCGGCAACTACGTGGCACCGCACATCTTCGAACTGCGC
GACGCCGCGCAACTGACCGAGGAAGTGTTCGGCCCGATCCTGCACGTCGTGCGCTACAAGGCCGCCCACCTCGACGCCGT
GCTCGCTGGCATCGCGGCGAGCGGCTACGCGCTGACGCTCGGCGTGCAGTCGCGGATCGACGACACGGTGGCGTGCATCG
TCGACCGGCTCGCGATCGGCAACGTCTACGTCAACCGCAACATGATCGGCGCCGTCGTCGGCACGCAGCCGTTCGGCGGC
TCGGGCCTGTCCGGCACCGGGCCGAAGGCCGGCGGCCCGCATTATCTGCCGCGCTTCACGCTGGAACAGACGGTGTCGAT
CAACACCGCGGCGGCCGGCGGCAACGCTGCGTTGCTGGCCGGCGACGAGTGA

Upstream 100 bases:

>100_bases
CGCGGTGCCAATATTGGAGTCGGGCGGCGGCGTATTTGCGGGGCGGCTGATGCGTCCCGCACACACCGCCCGCACCGCGG
ATTCTTCGCAAGGAGCGATC

Downstream 100 bases:

>100_bases
TACGTCATCCTGAGGCGCCGTCGCGCAGCGATGGCCTCGAAGGATGGGCCGCCGTCACCGTCGCTGTCATCCTTCGAGGC
TCGCTACGCTCGCGCCTCAG

Product: bifunctional proline dehydrogenase/pyrroline-5-carboxylate dehydrogenase

Products: NA

Alternate protein names: Proline dehydrogenase; Proline oxidase; Delta-1-pyrroline-5-carboxylate dehydrogenase; P5C dehydrogenase [H]

Number of amino acids: Translated: 1003; Mature: 1002

Protein sequence:

>1003_residues
MPPDSPHPEFDAAYAPDDATLAAALIAVMPRDPAREAPIDTTATGLIAAIRAGDHHLGSVEAMLREYALSSKEGLALMVL
AEALLRVPDAATADAFIEDRLGQGDFAHHRIKSDALLVNASAWALGLSARVVHAGDTPQSTLAALAKRIGAPAVRAATRQ
AMRLLGNHFVLGETIDDALARAQADAADGVRYSYDMLGEGARTRADAERYFASYAQAIDAIGRAAGNARLPARPGISVKL
SALHPRFEAVSRDRVLRELTPRLIELARKAKDHDLGFTVDAEEADRLELSLEVFAACLADPSLKGWDGYGLAVQAYQKRA
SAVIDYVDALAQRHDRRLMLRLVKGAYWDTEIKRAQERGLADYPVFSRKAMTDLNYLHCVQKLLGLRQRIFPQFASHNAL
TVATVLDLAGDSDGYEFQRLHGMGEALYARLRAEHPELTCRIYAPVGGHRDLLAYLVRRLLENGANSSFVAQAGDDTVPV
EELLRRPEAIIGTPDNARHPHIPLPRDLYRPQRENSRGVEFGDRAALRRLLSEIDAARRPLPRVTPVTPEDAAAAAVAAA
RDGFAAWSRTPAETRAAALERAADLLEQRRANFVALLQDEAGKTLDDCISEVREAIDYCRYYAAEGRRLFGDGVALPGPT
GERNSLRLRGRGVFVAISPWNFPLAIFLGQITAALMAGNAVIAKPAEQTPVIGDAAVGLLHEAGVPRAALQLVQGDGAIG
AALVAHRDVAGVVFTGSTDVARAINRALAAKDGPIVPLIAETGGINTMIVDATALPEQVADDVVTSAFRSAGQRCSALRL
LFVQDDVAERMIEMIAGSARELKLGDPRDPATHLGPVIDAEAKVRLDAHIAAMTREARLHFAGAAPSTGNYVAPHIFELR
DAAQLTEEVFGPILHVVRYKAAHLDAVLAGIAASGYALTLGVQSRIDDTVACIVDRLAIGNVYVNRNMIGAVVGTQPFGG
SGLSGTGPKAGGPHYLPRFTLEQTVSINTAAAGGNAALLAGDE

Sequences:

>Translated_1003_residues
MPPDSPHPEFDAAYAPDDATLAAALIAVMPRDPAREAPIDTTATGLIAAIRAGDHHLGSVEAMLREYALSSKEGLALMVL
AEALLRVPDAATADAFIEDRLGQGDFAHHRIKSDALLVNASAWALGLSARVVHAGDTPQSTLAALAKRIGAPAVRAATRQ
AMRLLGNHFVLGETIDDALARAQADAADGVRYSYDMLGEGARTRADAERYFASYAQAIDAIGRAAGNARLPARPGISVKL
SALHPRFEAVSRDRVLRELTPRLIELARKAKDHDLGFTVDAEEADRLELSLEVFAACLADPSLKGWDGYGLAVQAYQKRA
SAVIDYVDALAQRHDRRLMLRLVKGAYWDTEIKRAQERGLADYPVFSRKAMTDLNYLHCVQKLLGLRQRIFPQFASHNAL
TVATVLDLAGDSDGYEFQRLHGMGEALYARLRAEHPELTCRIYAPVGGHRDLLAYLVRRLLENGANSSFVAQAGDDTVPV
EELLRRPEAIIGTPDNARHPHIPLPRDLYRPQRENSRGVEFGDRAALRRLLSEIDAARRPLPRVTPVTPEDAAAAAVAAA
RDGFAAWSRTPAETRAAALERAADLLEQRRANFVALLQDEAGKTLDDCISEVREAIDYCRYYAAEGRRLFGDGVALPGPT
GERNSLRLRGRGVFVAISPWNFPLAIFLGQITAALMAGNAVIAKPAEQTPVIGDAAVGLLHEAGVPRAALQLVQGDGAIG
AALVAHRDVAGVVFTGSTDVARAINRALAAKDGPIVPLIAETGGINTMIVDATALPEQVADDVVTSAFRSAGQRCSALRL
LFVQDDVAERMIEMIAGSARELKLGDPRDPATHLGPVIDAEAKVRLDAHIAAMTREARLHFAGAAPSTGNYVAPHIFELR
DAAQLTEEVFGPILHVVRYKAAHLDAVLAGIAASGYALTLGVQSRIDDTVACIVDRLAIGNVYVNRNMIGAVVGTQPFGG
SGLSGTGPKAGGPHYLPRFTLEQTVSINTAAAGGNAALLAGDE
>Mature_1002_residues
PPDSPHPEFDAAYAPDDATLAAALIAVMPRDPAREAPIDTTATGLIAAIRAGDHHLGSVEAMLREYALSSKEGLALMVLA
EALLRVPDAATADAFIEDRLGQGDFAHHRIKSDALLVNASAWALGLSARVVHAGDTPQSTLAALAKRIGAPAVRAATRQA
MRLLGNHFVLGETIDDALARAQADAADGVRYSYDMLGEGARTRADAERYFASYAQAIDAIGRAAGNARLPARPGISVKLS
ALHPRFEAVSRDRVLRELTPRLIELARKAKDHDLGFTVDAEEADRLELSLEVFAACLADPSLKGWDGYGLAVQAYQKRAS
AVIDYVDALAQRHDRRLMLRLVKGAYWDTEIKRAQERGLADYPVFSRKAMTDLNYLHCVQKLLGLRQRIFPQFASHNALT
VATVLDLAGDSDGYEFQRLHGMGEALYARLRAEHPELTCRIYAPVGGHRDLLAYLVRRLLENGANSSFVAQAGDDTVPVE
ELLRRPEAIIGTPDNARHPHIPLPRDLYRPQRENSRGVEFGDRAALRRLLSEIDAARRPLPRVTPVTPEDAAAAAVAAAR
DGFAAWSRTPAETRAAALERAADLLEQRRANFVALLQDEAGKTLDDCISEVREAIDYCRYYAAEGRRLFGDGVALPGPTG
ERNSLRLRGRGVFVAISPWNFPLAIFLGQITAALMAGNAVIAKPAEQTPVIGDAAVGLLHEAGVPRAALQLVQGDGAIGA
ALVAHRDVAGVVFTGSTDVARAINRALAAKDGPIVPLIAETGGINTMIVDATALPEQVADDVVTSAFRSAGQRCSALRLL
FVQDDVAERMIEMIAGSARELKLGDPRDPATHLGPVIDAEAKVRLDAHIAAMTREARLHFAGAAPSTGNYVAPHIFELRD
AAQLTEEVFGPILHVVRYKAAHLDAVLAGIAASGYALTLGVQSRIDDTVACIVDRLAIGNVYVNRNMIGAVVGTQPFGGS
GLSGTGPKAGGPHYLPRFTLEQTVSINTAAAGGNAALLAGDE

Specific function: Oxidizes proline to glutamate for use as a carbon and nitrogen source and also function as a transcriptional repressor of the put operon [H]

COG id: COG4230

COG function: function code C; Delta 1-pyrroline-5-carboxylate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the aldehyde dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI153266822, Length=516, Percent_Identity=29.4573643410853, Blast_Score=178, Evalue=2e-44,
Organism=Homo sapiens, GI21361176, Length=474, Percent_Identity=29.957805907173, Blast_Score=177, Evalue=6e-44,
Organism=Homo sapiens, GI25777736, Length=451, Percent_Identity=33.2594235033259, Blast_Score=176, Evalue=8e-44,
Organism=Homo sapiens, GI25777734, Length=451, Percent_Identity=33.2594235033259, Blast_Score=176, Evalue=8e-44,
Organism=Homo sapiens, GI238859541, Length=451, Percent_Identity=33.2594235033259, Blast_Score=176, Evalue=1e-43,
Organism=Homo sapiens, GI25777732, Length=472, Percent_Identity=30.0847457627119, Blast_Score=176, Evalue=1e-43,
Organism=Homo sapiens, GI25777730, Length=471, Percent_Identity=30.5732484076433, Blast_Score=171, Evalue=3e-42,
Organism=Homo sapiens, GI25777724, Length=452, Percent_Identity=29.646017699115, Blast_Score=165, Evalue=2e-40,
Organism=Homo sapiens, GI21614513, Length=413, Percent_Identity=29.5399515738499, Blast_Score=164, Evalue=3e-40,
Organism=Homo sapiens, GI12007648, Length=461, Percent_Identity=28.4164859002169, Blast_Score=156, Evalue=9e-38,
Organism=Homo sapiens, GI25777728, Length=406, Percent_Identity=29.8029556650246, Blast_Score=155, Evalue=2e-37,
Organism=Homo sapiens, GI238814322, Length=429, Percent_Identity=26.8065268065268, Blast_Score=150, Evalue=9e-36,
Organism=Homo sapiens, GI115387104, Length=452, Percent_Identity=26.9911504424779, Blast_Score=145, Evalue=1e-34,
Organism=Homo sapiens, GI4507229, Length=426, Percent_Identity=27.2300469483568, Blast_Score=140, Evalue=4e-33,
Organism=Homo sapiens, GI25777721, Length=439, Percent_Identity=26.4236902050114, Blast_Score=131, Evalue=3e-30,
Organism=Homo sapiens, GI188035924, Length=491, Percent_Identity=26.0692464358452, Blast_Score=129, Evalue=1e-29,
Organism=Homo sapiens, GI310128093, Length=474, Percent_Identity=26.3713080168776, Blast_Score=127, Evalue=4e-29,
Organism=Homo sapiens, GI310128103, Length=487, Percent_Identity=26.2833675564682, Blast_Score=127, Evalue=6e-29,
Organism=Homo sapiens, GI25777726, Length=451, Percent_Identity=26.6075388026608, Blast_Score=127, Evalue=7e-29,
Organism=Homo sapiens, GI11095441, Length=356, Percent_Identity=27.5280898876405, Blast_Score=119, Evalue=1e-26,
Organism=Homo sapiens, GI4502043, Length=414, Percent_Identity=27.2946859903382, Blast_Score=118, Evalue=2e-26,
Organism=Homo sapiens, GI238814371, Length=414, Percent_Identity=27.2946859903382, Blast_Score=118, Evalue=2e-26,
Organism=Homo sapiens, GI25952152, Length=452, Percent_Identity=28.0973451327434, Blast_Score=115, Evalue=2e-25,
Organism=Homo sapiens, GI71773324, Length=320, Percent_Identity=28.4375, Blast_Score=113, Evalue=8e-25,
Organism=Homo sapiens, GI310128091, Length=386, Percent_Identity=27.2020725388601, Blast_Score=107, Evalue=6e-23,
Organism=Homo sapiens, GI73695881, Length=323, Percent_Identity=26.9349845201238, Blast_Score=104, Evalue=5e-22,
Organism=Homo sapiens, GI73695879, Length=323, Percent_Identity=26.9349845201238, Blast_Score=104, Evalue=5e-22,
Organism=Homo sapiens, GI206597441, Length=427, Percent_Identity=22.7166276346604, Blast_Score=102, Evalue=3e-21,
Organism=Homo sapiens, GI206597439, Length=427, Percent_Identity=22.7166276346604, Blast_Score=102, Evalue=3e-21,
Organism=Homo sapiens, GI22907049, Length=427, Percent_Identity=22.7166276346604, Blast_Score=102, Evalue=3e-21,
Organism=Homo sapiens, GI4557303, Length=322, Percent_Identity=24.223602484472, Blast_Score=90, Evalue=1e-17,
Organism=Homo sapiens, GI73466520, Length=322, Percent_Identity=24.223602484472, Blast_Score=89, Evalue=2e-17,
Organism=Homo sapiens, GI310128087, Length=297, Percent_Identity=26.9360269360269, Blast_Score=87, Evalue=9e-17,
Organism=Homo sapiens, GI310128089, Length=324, Percent_Identity=26.8518518518519, Blast_Score=83, Evalue=1e-15,
Organism=Homo sapiens, GI301500698, Length=295, Percent_Identity=25.7627118644068, Blast_Score=82, Evalue=3e-15,
Organism=Homo sapiens, GI310128095, Length=310, Percent_Identity=26.1290322580645, Blast_Score=78, Evalue=4e-14,
Organism=Homo sapiens, GI310128101, Length=237, Percent_Identity=26.5822784810127, Blast_Score=74, Evalue=5e-13,
Organism=Homo sapiens, GI310128099, Length=237, Percent_Identity=26.5822784810127, Blast_Score=74, Evalue=7e-13,
Organism=Homo sapiens, GI310128097, Length=247, Percent_Identity=27.1255060728745, Blast_Score=69, Evalue=2e-11,
Organism=Escherichia coli, GI1787250, Length=981, Percent_Identity=47.7064220183486, Blast_Score=847, Evalue=0.0,
Organism=Escherichia coli, GI1789015, Length=446, Percent_Identity=32.9596412556054, Blast_Score=179, Evalue=6e-46,
Organism=Escherichia coli, GI87081896, Length=447, Percent_Identity=31.7673378076063, Blast_Score=167, Evalue=4e-42,
Organism=Escherichia coli, GI1788042, Length=429, Percent_Identity=32.4009324009324, Blast_Score=164, Evalue=3e-41,
Organism=Escherichia coli, GI1787558, Length=449, Percent_Identity=32.0712694877506, Blast_Score=158, Evalue=2e-39,
Organism=Escherichia coli, GI1787684, Length=443, Percent_Identity=30.0225733634311, Blast_Score=152, Evalue=1e-37,
Organism=Escherichia coli, GI1787715, Length=418, Percent_Identity=29.4258373205742, Blast_Score=132, Evalue=1e-31,
Organism=Escherichia coli, GI1786504, Length=447, Percent_Identity=27.2930648769575, Blast_Score=126, Evalue=8e-30,
Organism=Escherichia coli, GI87081926, Length=451, Percent_Identity=25.7206208425721, Blast_Score=116, Evalue=6e-27,
Organism=Escherichia coli, GI87082295, Length=459, Percent_Identity=27.8867102396514, Blast_Score=114, Evalue=3e-26,
Organism=Escherichia coli, GI1787653, Length=375, Percent_Identity=25.3333333333333, Blast_Score=74, Evalue=5e-14,
Organism=Caenorhabditis elegans, GI17534447, Length=464, Percent_Identity=34.2672413793103, Blast_Score=191, Evalue=2e-48,
Organism=Caenorhabditis elegans, GI115532534, Length=357, Percent_Identity=36.1344537815126, Blast_Score=177, Evalue=3e-44,
Organism=Caenorhabditis elegans, GI115534176, Length=488, Percent_Identity=28.6885245901639, Blast_Score=157, Evalue=4e-38,
Organism=Caenorhabditis elegans, GI25144435, Length=441, Percent_Identity=30.1587301587302, Blast_Score=153, Evalue=4e-37,
Organism=Caenorhabditis elegans, GI133930964, Length=442, Percent_Identity=28.5067873303167, Blast_Score=150, Evalue=5e-36,
Organism=Caenorhabditis elegans, GI17534119, Length=453, Percent_Identity=29.3598233995585, Blast_Score=148, Evalue=1e-35,
Organism=Caenorhabditis elegans, GI17562198, Length=446, Percent_Identity=29.372197309417, Blast_Score=148, Evalue=1e-35,
Organism=Caenorhabditis elegans, GI25143874, Length=451, Percent_Identity=26.3858093126386, Blast_Score=148, Evalue=2e-35,
Organism=Caenorhabditis elegans, GI25143876, Length=451, Percent_Identity=26.1640798226164, Blast_Score=147, Evalue=3e-35,
Organism=Caenorhabditis elegans, GI17551164, Length=447, Percent_Identity=27.5167785234899, Blast_Score=145, Evalue=1e-34,
Organism=Caenorhabditis elegans, GI32564736, Length=422, Percent_Identity=29.8578199052133, Blast_Score=144, Evalue=2e-34,
Organism=Caenorhabditis elegans, GI32564151, Length=402, Percent_Identity=31.8407960199005, Blast_Score=139, Evalue=5e-33,
Organism=Caenorhabditis elegans, GI71995606, Length=450, Percent_Identity=28.6666666666667, Blast_Score=132, Evalue=1e-30,
Organism=Caenorhabditis elegans, GI71995613, Length=407, Percent_Identity=28.5012285012285, Blast_Score=125, Evalue=1e-28,
Organism=Caenorhabditis elegans, GI71986308, Length=400, Percent_Identity=26, Blast_Score=122, Evalue=1e-27,
Organism=Caenorhabditis elegans, GI71990744, Length=296, Percent_Identity=31.0810810810811, Blast_Score=99, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI25146391, Length=451, Percent_Identity=23.9467849223947, Blast_Score=89, Evalue=9e-18,
Organism=Caenorhabditis elegans, GI32566756, Length=451, Percent_Identity=23.9467849223947, Blast_Score=89, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI25146394, Length=451, Percent_Identity=23.9467849223947, Blast_Score=89, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI17564084, Length=450, Percent_Identity=23.1111111111111, Blast_Score=85, Evalue=2e-16,
Organism=Saccharomyces cerevisiae, GI6320917, Length=446, Percent_Identity=32.2869955156951, Blast_Score=174, Evalue=5e-44,
Organism=Saccharomyces cerevisiae, GI6324950, Length=427, Percent_Identity=28.1030444964871, Blast_Score=156, Evalue=1e-38,
Organism=Saccharomyces cerevisiae, GI6323822, Length=448, Percent_Identity=29.2410714285714, Blast_Score=152, Evalue=2e-37,
Organism=Saccharomyces cerevisiae, GI6321826, Length=444, Percent_Identity=28.3783783783784, Blast_Score=151, Evalue=4e-37,
Organism=Saccharomyces cerevisiae, GI6323821, Length=447, Percent_Identity=28.8590604026846, Blast_Score=147, Evalue=6e-36,
Organism=Saccharomyces cerevisiae, GI6319478, Length=450, Percent_Identity=25.7777777777778, Blast_Score=144, Evalue=7e-35,
Organism=Saccharomyces cerevisiae, GI6325196, Length=449, Percent_Identity=26.9487750556793, Blast_Score=132, Evalue=3e-31,
Organism=Drosophila melanogaster, GI24668425, Length=450, Percent_Identity=32, Blast_Score=191, Evalue=2e-48,
Organism=Drosophila melanogaster, GI24668417, Length=450, Percent_Identity=32, Blast_Score=191, Evalue=2e-48,
Organism=Drosophila melanogaster, GI24668413, Length=450, Percent_Identity=32, Blast_Score=191, Evalue=2e-48,
Organism=Drosophila melanogaster, GI20129399, Length=445, Percent_Identity=31.2359550561798, Blast_Score=174, Evalue=2e-43,
Organism=Drosophila melanogaster, GI281362580, Length=436, Percent_Identity=30.5045871559633, Blast_Score=174, Evalue=3e-43,
Organism=Drosophila melanogaster, GI62472918, Length=436, Percent_Identity=30.5045871559633, Blast_Score=174, Evalue=3e-43,
Organism=Drosophila melanogaster, GI62472926, Length=436, Percent_Identity=30.5045871559633, Blast_Score=174, Evalue=3e-43,
Organism=Drosophila melanogaster, GI62472936, Length=436, Percent_Identity=30.5045871559633, Blast_Score=174, Evalue=3e-43,
Organism=Drosophila melanogaster, GI21356737, Length=436, Percent_Identity=30.5045871559633, Blast_Score=174, Evalue=3e-43,
Organism=Drosophila melanogaster, GI24650465, Length=425, Percent_Identity=28.7058823529412, Blast_Score=153, Evalue=7e-37,
Organism=Drosophila melanogaster, GI28571806, Length=455, Percent_Identity=30.1098901098901, Blast_Score=149, Evalue=1e-35,
Organism=Drosophila melanogaster, GI28571798, Length=455, Percent_Identity=30.1098901098901, Blast_Score=149, Evalue=1e-35,
Organism=Drosophila melanogaster, GI28571796, Length=455, Percent_Identity=30.1098901098901, Blast_Score=149, Evalue=1e-35,
Organism=Drosophila melanogaster, GI28571794, Length=455, Percent_Identity=30.1098901098901, Blast_Score=149, Evalue=1e-35,
Organism=Drosophila melanogaster, GI28571802, Length=455, Percent_Identity=30.1098901098901, Blast_Score=149, Evalue=1e-35,
Organism=Drosophila melanogaster, GI28571800, Length=455, Percent_Identity=30.1098901098901, Blast_Score=149, Evalue=1e-35,
Organism=Drosophila melanogaster, GI24585660, Length=463, Percent_Identity=26.3498920086393, Blast_Score=142, Evalue=1e-33,
Organism=Drosophila melanogaster, GI28574525, Length=464, Percent_Identity=26.0775862068966, Blast_Score=124, Evalue=4e-28,
Organism=Drosophila melanogaster, GI24666674, Length=454, Percent_Identity=25.7709251101322, Blast_Score=123, Evalue=6e-28,
Organism=Drosophila melanogaster, GI24638878, Length=400, Percent_Identity=27.5, Blast_Score=105, Evalue=2e-22,
Organism=Drosophila melanogaster, GI24638876, Length=400, Percent_Identity=27.5, Blast_Score=105, Evalue=2e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016161
- InterPro:   IPR016163
- InterPro:   IPR016160
- InterPro:   IPR016162
- InterPro:   IPR015590
- InterPro:   IPR005933
- InterPro:   IPR002872 [H]

Pfam domain/function: PF00171 Aldedh; PF01619 Pro_dh [H]

EC number: =1.5.99.8; =1.5.1.12 [H]

Molecular weight: Translated: 107187; Mature: 107056

Theoretical pI: Translated: 6.39; Mature: 6.39

Prosite motif: PS00070 ALDEHYDE_DEHYDR_CYS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPPDSPHPEFDAAYAPDDATLAAALIAVMPRDPAREAPIDTTATGLIAAIRAGDHHLGSV
CCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHCCCCCCHHH
EAMLREYALSSKEGLALMVLAEALLRVPDAATADAFIEDRLGQGDFAHHRIKSDALLVNA
HHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCHHHHHHCCCEEEEEC
SAWALGLSARVVHAGDTPQSTLAALAKRIGAPAVRAATRQAMRLLGNHFVLGETIDDALA
CHHHCCCEEEEEECCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCEEECCHHHHHHH
RAQADAADGVRYSYDMLGEGARTRADAERYFASYAQAIDAIGRAAGNARLPARPGISVKL
HHHCCHHCCCEEEHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEE
SALHPRFEAVSRDRVLRELTPRLIELARKAKDHDLGFTVDAEEADRLELSLEVFAACLAD
ECCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEECCCCCHHHHHHHHHHHHHHCC
PSLKGWDGYGLAVQAYQKRASAVIDYVDALAQRHDRRLMLRLVKGAYWDTEIKRAQERGL
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCC
ADYPVFSRKAMTDLNYLHCVQKLLGLRQRIFPQFASHNALTVATVLDLAGDSDGYEFQRL
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEHHHHHHHCCCCCCCHHHHH
HGMGEALYARLRAEHPELTCRIYAPVGGHRDLLAYLVRRLLENGANSSFVAQAGDDTVPV
HCCHHHHHHHHHCCCCCEEEEEEECCCCCHHHHHHHHHHHHHCCCCCCEEEECCCCCCCH
EELLRRPEAIIGTPDNARHPHIPLPRDLYRPQRENSRGVEFGDRAALRRLLSEIDAARRP
HHHHCCCCEEECCCCCCCCCCCCCCHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCC
LPRVTPVTPEDAAAAAVAAARDGFAAWSRTPAETRAAALERAADLLEQRRANFVALLQDE
CCCCCCCCCCHHHHHHHHHHHCCHHHHCCCCHHHHHHHHHHHHHHHHHHCCCEEEEEECC
AGKTLDDCISEVREAIDYCRYYAAEGRRLFGDGVALPGPTGERNSLRLRGRGVFVAISPW
CCCCHHHHHHHHHHHHHHHHHHHHCCCEEECCCEECCCCCCCCCCEEEECCEEEEEECCC
NFPLAIFLGQITAALMAGNAVIAKPAEQTPVIGDAAVGLLHEAGVPRAALQLVQGDGAIG
CCHHHHHHHHHHHHHHCCCEEEECCCCCCCCCCHHHHHHHHHCCCCHHHHHHHCCCCCHH
AALVAHRDVAGVVFTGSTDVARAINRALAAKDGPIVPLIAETGGINTMIVDATALPEQVA
HHHHHHCCCCEEEEECCHHHHHHHHHHHHCCCCCEEEEEECCCCCCEEEEECHHCHHHHH
DDVVTSAFRSAGQRCSALRLLFVQDDVAERMIEMIAGSARELKLGDPRDPATHLGPVIDA
HHHHHHHHHHHHHHHHHHEEEEEHHHHHHHHHHHHCCCCCEECCCCCCCCHHHCCCCCCC
EAKVRLDAHIAAMTREARLHFAGAAPSTGNYVAPHIFELRDAAQLTEEVFGPILHVVRYK
CCEEEEHHHHHHHHHHHHEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
AAHLDAVLAGIAASGYALTLGVQSRIDDTVACIVDRLAIGNVYVNRNMIGAVVGTQPFGG
HHHHHHHHHHHHCCCEEEEEECHHHHHHHHHHHHHHHHHCCEEECCCEEEEEECCCCCCC
SGLSGTGPKAGGPHYLPRFTLEQTVSINTAAAGGNAALLAGDE
CCCCCCCCCCCCCCCCCCCCHHHEEEEEEECCCCCEEEEECCC
>Mature Secondary Structure 
PPDSPHPEFDAAYAPDDATLAAALIAVMPRDPAREAPIDTTATGLIAAIRAGDHHLGSV
CCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHCCCCCCHHH
EAMLREYALSSKEGLALMVLAEALLRVPDAATADAFIEDRLGQGDFAHHRIKSDALLVNA
HHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCHHHHHHCCCEEEEEC
SAWALGLSARVVHAGDTPQSTLAALAKRIGAPAVRAATRQAMRLLGNHFVLGETIDDALA
CHHHCCCEEEEEECCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCEEECCHHHHHHH
RAQADAADGVRYSYDMLGEGARTRADAERYFASYAQAIDAIGRAAGNARLPARPGISVKL
HHHCCHHCCCEEEHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEE
SALHPRFEAVSRDRVLRELTPRLIELARKAKDHDLGFTVDAEEADRLELSLEVFAACLAD
ECCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEECCCCCHHHHHHHHHHHHHHCC
PSLKGWDGYGLAVQAYQKRASAVIDYVDALAQRHDRRLMLRLVKGAYWDTEIKRAQERGL
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCC
ADYPVFSRKAMTDLNYLHCVQKLLGLRQRIFPQFASHNALTVATVLDLAGDSDGYEFQRL
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEHHHHHHHCCCCCCCHHHHH
HGMGEALYARLRAEHPELTCRIYAPVGGHRDLLAYLVRRLLENGANSSFVAQAGDDTVPV
HCCHHHHHHHHHCCCCCEEEEEEECCCCCHHHHHHHHHHHHHCCCCCCEEEECCCCCCCH
EELLRRPEAIIGTPDNARHPHIPLPRDLYRPQRENSRGVEFGDRAALRRLLSEIDAARRP
HHHHCCCCEEECCCCCCCCCCCCCCHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCC
LPRVTPVTPEDAAAAAVAAARDGFAAWSRTPAETRAAALERAADLLEQRRANFVALLQDE
CCCCCCCCCCHHHHHHHHHHHCCHHHHCCCCHHHHHHHHHHHHHHHHHHCCCEEEEEECC
AGKTLDDCISEVREAIDYCRYYAAEGRRLFGDGVALPGPTGERNSLRLRGRGVFVAISPW
CCCCHHHHHHHHHHHHHHHHHHHHCCCEEECCCEECCCCCCCCCCEEEECCEEEEEECCC
NFPLAIFLGQITAALMAGNAVIAKPAEQTPVIGDAAVGLLHEAGVPRAALQLVQGDGAIG
CCHHHHHHHHHHHHHHCCCEEEECCCCCCCCCCHHHHHHHHHCCCCHHHHHHHCCCCCHH
AALVAHRDVAGVVFTGSTDVARAINRALAAKDGPIVPLIAETGGINTMIVDATALPEQVA
HHHHHHCCCCEEEEECCHHHHHHHHHHHHCCCCCEEEEEECCCCCCEEEEECHHCHHHHH
DDVVTSAFRSAGQRCSALRLLFVQDDVAERMIEMIAGSARELKLGDPRDPATHLGPVIDA
HHHHHHHHHHHHHHHHHHEEEEEHHHHHHHHHHHHCCCCCEECCCCCCCCHHHCCCCCCC
EAKVRLDAHIAAMTREARLHFAGAAPSTGNYVAPHIFELRDAAQLTEEVFGPILHVVRYK
CCEEEEHHHHHHHHHHHHEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
AAHLDAVLAGIAASGYALTLGVQSRIDDTVACIVDRLAIGNVYVNRNMIGAVVGTQPFGG
HHHHHHHHHHHHCCCEEEEEECHHHHHHHHHHHHHHHHHCCEEECCCEEEEEECCCCCCC
SGLSGTGPKAGGPHYLPRFTLEQTVSINTAAAGGNAALLAGDE
CCCCCCCCCCCCCCCCCCCCHHHEEEEEEECCCCCEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7966312; 8905232; 9278503; 3325781; 12514740 [H]