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The map label for this gene is yadA [H]

Identifier: 86750771

GI number: 86750771

Start: 4202981

End: 4204237

Strand: Direct

Name: yadA [H]

Synonym: RPB_3661

Alternate gene names: 86750771

Gene position: 4202981-4204237 (Clockwise)

Preceding gene: 86750769

Following gene: 86750772

Centisome position: 78.83

GC content: 68.26

Gene sequence:

>1257_bases
ATGACAGCCCGGATGAACGACAGAGTTGGCGCGGCGTGGATTGGCGCATCTCTCATTCTCGCGGCGTTTCTGCTGCAGCC
GGGCCGCGCGATGGCGCAAACCACCGACCCGGTTCAGGTCGTGTCGGGTTGCGTCGCCAATGTCGCAGACCGGCAATTGG
CCTGCGGCCCGGGCGCCAGCACTGCCGGAAGCAATGATCGGTCGACGGCCATCGGCAGCAACGCTCAATCCGACGGCAGC
TCTGTCGCCATCGGTAGCAGTTCCATAGCAACCGGCAATAACTCGACCGCTATCGGCGACAACGCCAACGCGGTTGGATT
TGGGGATTCGACAGTGATCGGCTCCGGCGCCGGATCTGGAGGAGCCCGCAGCACGGTTATCGGCAGCGGGGCGGCCACCG
GCAACGAAGGAGCCATCGCCGTGGGACATCGCGCCGGCGTCGGACTGGGCTCGGGTCAGTACAGCATCGCGATGGGCGCG
GGCGGCGATACCGCGCAGTCCGCGTCGCATGCAATCGGCAATTTCAGCATCGCGATCGGCGGCGGCGACGGCCTATCGGC
CAACGGTGCCATTTCCAATGCGGCGTTCGGCACCGCGGTCGGCGCATCCAGCATCGCGGCGAACCAGTTCGACGCGGCGT
TTGGCGCCTTCTCGATCGCCAGCGGGGCGCGTAGCGCCGCATTCGGCGCCAACAGCGTCGCCGCCGGCGCGTCGTCGGTG
GCGCTGGGAGACGGCTCGTTTGCCCAAGGGACCCACGCTGTGTCCACCGGCTTCAATTCAGCGGCCACCGGTGTCAACAG
CGTGGCGCTCGGTGCCGAGGCTTCGGCGACGGCTTCCAACTCGGTGGCGATCGGCTCGCGTTCGGTCACGAGCGCGCCCA
ACACGGCATCGTTCGGGACGCCCGGCAATGAGCGCCGGCTCACCAACGTGGCCGCCGGCATCAGCCAGACCGACGCGGTC
AATGTCGGGCAGCTCGCGGCAGTCACCAGCGGCCTTCAGTCGCAGATCACCAACAACCGCTCCGAAGCGCGGCGCGGCAT
CGCCGCGGCGGTCGCCACCGCCAGCGCGCCGATGCCCTCGGCGCCAGGCAAGACGACGTGGCAGATCCGCGGCTCCACCT
TCCAGAACGAATATGGCATCGGCGTCGGTTTTGCCCACCAACTGCGGACGGCGATGCCGCTCAACATCGTCGGCGGCTAC
GGCAATGGCGGCGGCGCCGAGCACACCGCCTATGTCGGCGTCGGCGGCGAGTTCTGA

Upstream 100 bases:

>100_bases
GCGCTCCAACCCAACTCGGCTGCGGTCCGCCCCAAGACGACGCCGTCCAATCCGGTGAGGTTGACGACGAAACCTCAATC
AGCGGGGAGCGGAGCGCATC

Downstream 100 bases:

>100_bases
GCCCGCCGCCGACCGCGCCTGCCGGTCGCTTGCGCGGGATCAATCCTGCGACACGGATCGCTTGCTAGGGTCGCGCAAAC
GAACACAACAGGTGGTGTCA

Product: hemagluttinin-like protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 418; Mature: 417

Protein sequence:

>418_residues
MTARMNDRVGAAWIGASLILAAFLLQPGRAMAQTTDPVQVVSGCVANVADRQLACGPGASTAGSNDRSTAIGSNAQSDGS
SVAIGSSSIATGNNSTAIGDNANAVGFGDSTVIGSGAGSGGARSTVIGSGAATGNEGAIAVGHRAGVGLGSGQYSIAMGA
GGDTAQSASHAIGNFSIAIGGGDGLSANGAISNAAFGTAVGASSIAANQFDAAFGAFSIASGARSAAFGANSVAAGASSV
ALGDGSFAQGTHAVSTGFNSAATGVNSVALGAEASATASNSVAIGSRSVTSAPNTASFGTPGNERRLTNVAAGISQTDAV
NVGQLAAVTSGLQSQITNNRSEARRGIAAAVATASAPMPSAPGKTTWQIRGSTFQNEYGIGVGFAHQLRTAMPLNIVGGY
GNGGGAEHTAYVGVGGEF

Sequences:

>Translated_418_residues
MTARMNDRVGAAWIGASLILAAFLLQPGRAMAQTTDPVQVVSGCVANVADRQLACGPGASTAGSNDRSTAIGSNAQSDGS
SVAIGSSSIATGNNSTAIGDNANAVGFGDSTVIGSGAGSGGARSTVIGSGAATGNEGAIAVGHRAGVGLGSGQYSIAMGA
GGDTAQSASHAIGNFSIAIGGGDGLSANGAISNAAFGTAVGASSIAANQFDAAFGAFSIASGARSAAFGANSVAAGASSV
ALGDGSFAQGTHAVSTGFNSAATGVNSVALGAEASATASNSVAIGSRSVTSAPNTASFGTPGNERRLTNVAAGISQTDAV
NVGQLAAVTSGLQSQITNNRSEARRGIAAAVATASAPMPSAPGKTTWQIRGSTFQNEYGIGVGFAHQLRTAMPLNIVGGY
GNGGGAEHTAYVGVGGEF
>Mature_417_residues
TARMNDRVGAAWIGASLILAAFLLQPGRAMAQTTDPVQVVSGCVANVADRQLACGPGASTAGSNDRSTAIGSNAQSDGSS
VAIGSSSIATGNNSTAIGDNANAVGFGDSTVIGSGAGSGGARSTVIGSGAATGNEGAIAVGHRAGVGLGSGQYSIAMGAG
GDTAQSASHAIGNFSIAIGGGDGLSANGAISNAAFGTAVGASSIAANQFDAAFGAFSIASGARSAAFGANSVAAGASSVA
LGDGSFAQGTHAVSTGFNSAATGVNSVALGAEASATASNSVAIGSRSVTSAPNTASFGTPGNERRLTNVAAGISQTDAVN
VGQLAAVTSGLQSQITNNRSEARRGIAAAVATASAPMPSAPGKTTWQIRGSTFQNEYGIGVGFAHQLRTAMPLNIVGGYG
NGGGAEHTAYVGVGGEF

Specific function: Collagen-binding outer membrane protein forming a fibrillar matrix on the bacterial cell surface. Promotes initial attachment and invasion of eukaryotic cells. Also protects the bacteria by being responsible for agglutination, serum resistance, complement

COG id: COG5295

COG function: function code UW; Autotransporter adhesin

Gene ontology:

Cell location: Cell outer membrane [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the autotransporter-2 (TC 1.B.40) / oligomeric coiled-coil adhesin (Oca) family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008640
- InterPro:   IPR008635
- InterPro:   IPR008126
- InterPro:   IPR005594 [H]

Pfam domain/function: PF05658 Hep_Hag; PF05662 HIM; PF03895 YadA [H]

EC number: NA

Molecular weight: Translated: 39843; Mature: 39712

Theoretical pI: Translated: 6.67; Mature: 6.67

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTARMNDRVGAAWIGASLILAAFLLQPGRAMAQTTDPVQVVSGCVANVADRQLACGPGAS
CCCCCCCCCCHHHHHHHHHHHHHHHCCCCHHHCCCCHHHHHHHHHHHHHCCEEECCCCCC
TAGSNDRSTAIGSNAQSDGSSVAIGSSSIATGNNSTAIGDNANAVGFGDSTVIGSGAGSG
CCCCCCCCCCCCCCCCCCCCEEEECCCCEECCCCCCEECCCCCEEECCCCEEEECCCCCC
GARSTVIGSGAATGNEGAIAVGHRAGVGLGSGQYSIAMGAGGDTAQSASHAIGNFSIAIG
CCCEEEEECCCCCCCCCCEEEECCCCCCCCCCCEEEEECCCCCCHHHHHHCCCEEEEEEE
GGDGLSANGAISNAAFGTAVGASSIAANQFDAAFGAFSIASGARSAAFGANSVAAGASSV
CCCCCCCCCCCCCCCHHHHHCCHHHHHHHHHHHHHHHHHHCCCCHHHCCCCHHHCCCCEE
ALGDGSFAQGTHAVSTGFNSAATGVNSVALGAEASATASNSVAIGSRSVTSAPNTASFGT
EECCCCCCCCCHHHHCCCCHHHCCCCCEEECCCCCCCCCCEEEECCCCCCCCCCCCCCCC
PGNERRLTNVAAGISQTDAVNVGQLAAVTSGLQSQITNNRSEARRGIAAAVATASAPMPS
CCCCCHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCC
APGKTTWQIRGSTFQNEYGIGVGFAHQLRTAMPLNIVGGYGNGGGAEHTAYVGVGGEF
CCCCEEEEEECCCCCCCCCCCCCHHHHHHHCCCEEEEECCCCCCCCCCEEEEECCCCC
>Mature Secondary Structure 
TARMNDRVGAAWIGASLILAAFLLQPGRAMAQTTDPVQVVSGCVANVADRQLACGPGAS
CCCCCCCCCHHHHHHHHHHHHHHHCCCCHHHCCCCHHHHHHHHHHHHHCCEEECCCCCC
TAGSNDRSTAIGSNAQSDGSSVAIGSSSIATGNNSTAIGDNANAVGFGDSTVIGSGAGSG
CCCCCCCCCCCCCCCCCCCCEEEECCCCEECCCCCCEECCCCCEEECCCCEEEECCCCCC
GARSTVIGSGAATGNEGAIAVGHRAGVGLGSGQYSIAMGAGGDTAQSASHAIGNFSIAIG
CCCEEEEECCCCCCCCCCEEEECCCCCCCCCCCEEEEECCCCCCHHHHHHCCCEEEEEEE
GGDGLSANGAISNAAFGTAVGASSIAANQFDAAFGAFSIASGARSAAFGANSVAAGASSV
CCCCCCCCCCCCCCCHHHHHCCHHHHHHHHHHHHHHHHHHCCCCHHHCCCCHHHCCCCEE
ALGDGSFAQGTHAVSTGFNSAATGVNSVALGAEASATASNSVAIGSRSVTSAPNTASFGT
EECCCCCCCCCHHHHCCCCHHHCCCCCEEECCCCCCCCCCEEEECCCCCCCCCCCCCCCC
PGNERRLTNVAAGISQTDAVNVGQLAAVTSGLQSQITNNRSEARRGIAAAVATASAPMPS
CCCCCHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCC
APGKTTWQIRGSTFQNEYGIGVGFAHQLRTAMPLNIVGGYGNGGGAEHTAYVGVGGEF
CCCCEEEEEECCCCCCCCCCCCCHHHHHHHCCCEEEEECCCCCCCCCCEEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 2761389; 7934875; 2592347; 1548243 [H]