| Definition | Rhodopseudomonas palustris HaA2, complete genome. |
|---|---|
| Accession | NC_007778 |
| Length | 5,331,656 |
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The map label for this gene is caiD [H]
Identifier: 86750712
GI number: 86750712
Start: 4134625
End: 4135404
Strand: Direct
Name: caiD [H]
Synonym: RPB_3602
Alternate gene names: 86750712
Gene position: 4134625-4135404 (Clockwise)
Preceding gene: 86750710
Following gene: 86750716
Centisome position: 77.55
GC content: 68.33
Gene sequence:
>780_bases ATGGCGCTGCAATTCTCCACCGTGACCCGCAAGGGCCCGATCACCATCGTCACGCTGTCGCGACCTGAGGTCTACAACGC GCTGCACACCGACGCGCATTACGAACTCGAAGGCGTGTTCAACGACTTCTCCGCCGACCCCGAGCAATGGGTCGCGATCA TCACCGGCGCCGGCGACAAGGCGTTTTGCGCCGGCAATGATCTGAAGTGGCAGGCCTCGGGCGGCAAGCGCGGCTGGGGC GAGACCGGCTTCGCCGGGCTGACCTCGCGGTTCGATTGCGACAAGCCGATCATCGCCGCGGTCAACGGCGTGGCGATGGG CGGCGGTTTCGAAATCGCACTCGCCTGCGACTTGATCATCGCCGCGGAGAACGCCACATTCGCGCTGCCGGAGCCGCGCG TCGGCCTCGCCGCGCTGGCCGGCGGCCTGCACCGCCTGCCCCGCCAGATCGGGCTGAAGCGCGCGATGGGCATGATCCTC ACCGCCCGCCACGTCCCCGCCCGGGAGGGGCTGGAACTCGGCTTCGTCAACGAAGTCGTCCCCCCGGGGGAGGCCCTCGC CGCCGCCGAGCGCTGGGCCGAAGCGATCTGCGCCGTCTCTCCGATGTCGATCCGCGCCTCGAAGCAGGCCCTGATGCGCG GCCTCGAAGTCTCCTTGCCGCAAGCGATCGCCGAGCAGCGCGACTATCCGGCGGTCAAAGCCATGGTCGCCTCGCAGGAC TACATCGAAGGCCCGAAGGCGTTCTCGGAGAAGCGCAAGCCGAACTGGGTTGGGAAGTAG
Upstream 100 bases:
>100_bases TTGTTGATCTTGTTAAGCGAGTGATTAACATGCGCCGCGAACGACAAGTCAAGCGCGCTTCAGCCGCACCAATTCTGCCC AACGAAAAGAGGAAACGTCG
Downstream 100 bases:
>100_bases TTCGTCGGCCCGAAGTAGTTCGTCGGCCCGCCTCTCCGCGTCATTGCGAGCGAAGCGACGCAATCCAGAAGCTCCGAGCG CAGCGCTGGATTGCTTCGTC
Product: enoyl-CoA hydratase
Products: L-Carnitine.; L-carnitinyl-CoA [C]
Alternate protein names: Crotonobetainyl-CoA hydratase [H]
Number of amino acids: Translated: 259; Mature: 258
Protein sequence:
>259_residues MALQFSTVTRKGPITIVTLSRPEVYNALHTDAHYELEGVFNDFSADPEQWVAIITGAGDKAFCAGNDLKWQASGGKRGWG ETGFAGLTSRFDCDKPIIAAVNGVAMGGGFEIALACDLIIAAENATFALPEPRVGLAALAGGLHRLPRQIGLKRAMGMIL TARHVPAREGLELGFVNEVVPPGEALAAAERWAEAICAVSPMSIRASKQALMRGLEVSLPQAIAEQRDYPAVKAMVASQD YIEGPKAFSEKRKPNWVGK
Sequences:
>Translated_259_residues MALQFSTVTRKGPITIVTLSRPEVYNALHTDAHYELEGVFNDFSADPEQWVAIITGAGDKAFCAGNDLKWQASGGKRGWG ETGFAGLTSRFDCDKPIIAAVNGVAMGGGFEIALACDLIIAAENATFALPEPRVGLAALAGGLHRLPRQIGLKRAMGMIL TARHVPAREGLELGFVNEVVPPGEALAAAERWAEAICAVSPMSIRASKQALMRGLEVSLPQAIAEQRDYPAVKAMVASQD YIEGPKAFSEKRKPNWVGK >Mature_258_residues ALQFSTVTRKGPITIVTLSRPEVYNALHTDAHYELEGVFNDFSADPEQWVAIITGAGDKAFCAGNDLKWQASGGKRGWGE TGFAGLTSRFDCDKPIIAAVNGVAMGGGFEIALACDLIIAAENATFALPEPRVGLAALAGGLHRLPRQIGLKRAMGMILT ARHVPAREGLELGFVNEVVPPGEALAAAERWAEAICAVSPMSIRASKQALMRGLEVSLPQAIAEQRDYPAVKAMVASQDY IEGPKAFSEKRKPNWVGK
Specific function: Catalyzes the reversible dehydration of L-carnitinyl-CoA to crotonobetainyl-CoA [H]
COG id: COG1024
COG function: function code I; Enoyl-CoA hydratase/carnithine racemase
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the enoyl-CoA hydratase/isomerase family [H]
Homologues:
Organism=Homo sapiens, GI194097323, Length=248, Percent_Identity=33.4677419354839, Blast_Score=130, Evalue=1e-30, Organism=Homo sapiens, GI70995211, Length=255, Percent_Identity=33.3333333333333, Blast_Score=107, Evalue=1e-23, Organism=Homo sapiens, GI20127408, Length=180, Percent_Identity=32.2222222222222, Blast_Score=89, Evalue=3e-18, Organism=Homo sapiens, GI37594469, Length=189, Percent_Identity=32.2751322751323, Blast_Score=87, Evalue=2e-17, Organism=Homo sapiens, GI37594471, Length=203, Percent_Identity=31.5270935960591, Blast_Score=86, Evalue=2e-17, Organism=Homo sapiens, GI31542718, Length=251, Percent_Identity=29.8804780876494, Blast_Score=86, Evalue=2e-17, Organism=Homo sapiens, GI4502327, Length=257, Percent_Identity=31.1284046692607, Blast_Score=85, Evalue=6e-17, Organism=Homo sapiens, GI68989263, Length=190, Percent_Identity=33.1578947368421, Blast_Score=78, Evalue=8e-15, Organism=Homo sapiens, GI150378541, Length=252, Percent_Identity=29.3650793650794, Blast_Score=78, Evalue=1e-14, Organism=Homo sapiens, GI45643119, Length=229, Percent_Identity=27.0742358078603, Blast_Score=72, Evalue=6e-13, Organism=Homo sapiens, GI260275230, Length=229, Percent_Identity=27.0742358078603, Blast_Score=72, Evalue=6e-13, Organism=Homo sapiens, GI260274832, Length=229, Percent_Identity=27.0742358078603, Blast_Score=72, Evalue=7e-13, Organism=Homo sapiens, GI213417737, Length=227, Percent_Identity=28.6343612334802, Blast_Score=69, Evalue=6e-12, Organism=Homo sapiens, GI157694516, Length=227, Percent_Identity=28.6343612334802, Blast_Score=68, Evalue=6e-12, Organism=Homo sapiens, GI25453481, Length=248, Percent_Identity=25, Blast_Score=67, Evalue=1e-11, Organism=Homo sapiens, GI51538573, Length=248, Percent_Identity=25, Blast_Score=67, Evalue=1e-11, Organism=Homo sapiens, GI4757966, Length=240, Percent_Identity=25.4166666666667, Blast_Score=67, Evalue=2e-11, Organism=Homo sapiens, GI51538581, Length=240, Percent_Identity=25.4166666666667, Blast_Score=67, Evalue=2e-11, Organism=Escherichia coli, GI221142681, Length=259, Percent_Identity=43.6293436293436, Blast_Score=188, Evalue=3e-49, Organism=Escherichia coli, GI1787659, Length=253, Percent_Identity=34.7826086956522, Blast_Score=141, Evalue=3e-35, Organism=Escherichia coli, GI1788597, Length=250, Percent_Identity=32.4, Blast_Score=123, Evalue=2e-29, Organism=Escherichia coli, GI87082183, Length=260, Percent_Identity=29.2307692307692, Blast_Score=106, Evalue=2e-24, Organism=Escherichia coli, GI1787660, Length=256, Percent_Identity=33.203125, Blast_Score=89, Evalue=2e-19, Organism=Escherichia coli, GI1788682, Length=201, Percent_Identity=28.8557213930348, Blast_Score=85, Evalue=5e-18, Organism=Escherichia coli, GI1790281, Length=153, Percent_Identity=33.3333333333333, Blast_Score=67, Evalue=1e-12, Organism=Caenorhabditis elegans, GI17554946, Length=258, Percent_Identity=34.1085271317829, Blast_Score=144, Evalue=4e-35, Organism=Caenorhabditis elegans, GI25145438, Length=255, Percent_Identity=34.1176470588235, Blast_Score=133, Evalue=1e-31, Organism=Caenorhabditis elegans, GI17560910, Length=255, Percent_Identity=30.5882352941176, Blast_Score=115, Evalue=2e-26, Organism=Caenorhabditis elegans, GI17540714, Length=226, Percent_Identity=32.7433628318584, Blast_Score=108, Evalue=3e-24, Organism=Caenorhabditis elegans, GI17534483, Length=210, Percent_Identity=32.3809523809524, Blast_Score=98, Evalue=4e-21, Organism=Caenorhabditis elegans, GI17535521, Length=219, Percent_Identity=28.7671232876712, Blast_Score=96, Evalue=2e-20, Organism=Caenorhabditis elegans, GI17549921, Length=236, Percent_Identity=28.3898305084746, Blast_Score=92, Evalue=2e-19, Organism=Caenorhabditis elegans, GI17536985, Length=259, Percent_Identity=27.4131274131274, Blast_Score=91, Evalue=4e-19, Organism=Caenorhabditis elegans, GI17558304, Length=218, Percent_Identity=24.7706422018349, Blast_Score=79, Evalue=3e-15, Organism=Caenorhabditis elegans, GI17508951, Length=218, Percent_Identity=25.6880733944954, Blast_Score=74, Evalue=1e-13, Organism=Caenorhabditis elegans, GI25144276, Length=218, Percent_Identity=25.6880733944954, Blast_Score=74, Evalue=1e-13, Organism=Caenorhabditis elegans, GI17508953, Length=218, Percent_Identity=25.6880733944954, Blast_Score=73, Evalue=1e-13, Organism=Caenorhabditis elegans, GI17540306, Length=153, Percent_Identity=30.0653594771242, Blast_Score=64, Evalue=8e-11, Organism=Saccharomyces cerevisiae, GI6320241, Length=192, Percent_Identity=25, Blast_Score=68, Evalue=2e-12, Organism=Drosophila melanogaster, GI20129971, Length=241, Percent_Identity=35.6846473029046, Blast_Score=132, Evalue=2e-31, Organism=Drosophila melanogaster, GI24653477, Length=241, Percent_Identity=35.6846473029046, Blast_Score=132, Evalue=2e-31, Organism=Drosophila melanogaster, GI24653139, Length=260, Percent_Identity=34.2307692307692, Blast_Score=120, Evalue=1e-27, Organism=Drosophila melanogaster, GI21357171, Length=263, Percent_Identity=30.0380228136882, Blast_Score=107, Evalue=7e-24, Organism=Drosophila melanogaster, GI24650670, Length=210, Percent_Identity=29.5238095238095, Blast_Score=93, Evalue=2e-19, Organism=Drosophila melanogaster, GI19920382, Length=217, Percent_Identity=29.0322580645161, Blast_Score=89, Evalue=3e-18, Organism=Drosophila melanogaster, GI24654903, Length=182, Percent_Identity=26.3736263736264, Blast_Score=76, Evalue=2e-14, Organism=Drosophila melanogaster, GI19922422, Length=244, Percent_Identity=25.4098360655738, Blast_Score=70, Evalue=2e-12, Organism=Drosophila melanogaster, GI19921000, Length=186, Percent_Identity=31.1827956989247, Blast_Score=70, Evalue=2e-12, Organism=Drosophila melanogaster, GI24583077, Length=186, Percent_Identity=31.1827956989247, Blast_Score=69, Evalue=2e-12, Organism=Drosophila melanogaster, GI24583079, Length=186, Percent_Identity=31.1827956989247, Blast_Score=69, Evalue=2e-12, Organism=Drosophila melanogaster, GI28571730, Length=150, Percent_Identity=28.6666666666667, Blast_Score=67, Evalue=9e-12, Organism=Drosophila melanogaster, GI28571729, Length=150, Percent_Identity=28.6666666666667, Blast_Score=67, Evalue=1e-11,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR022852 - InterPro: IPR014748 - InterPro: IPR001753 - InterPro: IPR018376 [H]
Pfam domain/function: PF00378 ECH [H]
EC number: 4.2.1.- [C]
Molecular weight: Translated: 27644; Mature: 27513
Theoretical pI: Translated: 6.93; Mature: 6.93
Prosite motif: PS00166 ENOYL_COA_HYDRATASE
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
1.5 %Cys (Translated Protein) 2.7 %Met (Translated Protein) 4.2 %Cys+Met (Translated Protein) 1.6 %Cys (Mature Protein) 2.3 %Met (Mature Protein) 3.9 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MALQFSTVTRKGPITIVTLSRPEVYNALHTDAHYELEGVFNDFSADPEQWVAIITGAGDK CCEEECCCCCCCCEEEEEECCCHHHHHHHCCCCEEEEEHHCCCCCCCCCEEEEEECCCCC AFCAGNDLKWQASGGKRGWGETGFAGLTSRFDCDKPIIAAVNGVAMGGGFEIALACDLII EEECCCCEEEEECCCCCCCCCCCCHHCCCCCCCCCCHHHHHCCEEECCCEEEEEEEEEEE AAENATFALPEPRVGLAALAGGLHRLPRQIGLKRAMGMILTARHVPAREGLELGFVNEVV EECCCEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHCC PPGEALAAAERWAEAICAVSPMSIRASKQALMRGLEVSLPQAIAEQRDYPAVKAMVASQD CCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCHHHHHHHHCCCCHHHHHHHHCCH YIEGPKAFSEKRKPNWVGK HHCCCHHHHHCCCCCCCCC >Mature Secondary Structure ALQFSTVTRKGPITIVTLSRPEVYNALHTDAHYELEGVFNDFSADPEQWVAIITGAGDK CEEECCCCCCCCEEEEEECCCHHHHHHHCCCCEEEEEHHCCCCCCCCCEEEEEECCCCC AFCAGNDLKWQASGGKRGWGETGFAGLTSRFDCDKPIIAAVNGVAMGGGFEIALACDLII EEECCCCEEEEECCCCCCCCCCCCHHCCCCCCCCCCHHHHHCCEEECCCEEEEEEEEEEE AAENATFALPEPRVGLAALAGGLHRLPRQIGLKRAMGMILTARHVPAREGLELGFVNEVV EECCCEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHCC PPGEALAAAERWAEAICAVSPMSIRASKQALMRGLEVSLPQAIAEQRDYPAVKAMVASQD CCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCHHHHHHHHCCCCHHHHHHHHCCH YIEGPKAFSEKRKPNWVGK HHCCCHHHHHCCCCCCCCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: D-Carnitine; D-carnitinyl-CoA [C]
Specific reaction: D-Carnitine = L-Carnitine. D-carnitinyl-CoA = L-carnitinyl-CoA [C]
General reaction: Isomerases [C]
Inhibitor: NA
Structure determination priority: 10.0
TargetDB status: NA
Availability: NA
References: NA