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The map label for this gene is czcB [H]

Identifier: 86750671

GI number: 86750671

Start: 4076950

End: 4078191

Strand: Reverse

Name: czcB [H]

Synonym: RPB_3561

Alternate gene names: 86750671

Gene position: 4078191-4076950 (Counterclockwise)

Preceding gene: 86750672

Following gene: 86750670

Centisome position: 76.49

GC content: 66.67

Gene sequence:

>1242_bases
ATGTGGAAACACGTTACGCGAAGGCTGCGACGTGTGACGCGGAAGCGGCTGGTGCTGACCGGCTGCCTGGTCGTCGGCGT
CGCCGTGGCCGGCTCCATCGTCGCGGACCGCTACGCAGCCACCGAGGTCCATTCGGAGATCTCCAGCCAGTCGCGTCGCA
GCGCCGATCGCTACACCCCGAGCGCGGCGGAATGGGCGAGCCTGACCATCGAGAAGGTGAGCGATTTCAGCTTCCGCGCC
GAGCACGTCACCGAAGGCAAGATCGCCATCGACGAGGATCGCTCGACGCCTGTGTTCTCGCCTTATGCGGGTCGGGTGAC
GAAACTGCTGGCGCGCCCCGGCGATCATGTCGTGCAGGGTCAGCCGCTGTTCACGATCGAGGCGCCGGACACGGTGCAGG
CGCAGAACGATTTCATCGTCGCCTCCACCGCGCTGAACAAGGCGAAGTCGCAGCTCGAACTGGCGCAGTTTCAGGACAAG
CGTGCGCGCGATCTGTTCGACGGCAAGGCGGTGCCGCTGAAGGACTATCAGCAGGCCCAGGCGACGCTGACGAGCGCGCA
GAACGACATGCAGTCGGCGACCACGGCGCTCGAAGCCGCGCGCAACCGTTTGCGGATCCTCGGATTGACCGAGAGCGCGA
TCACGGCGTTTCAGGACAAGGGCAGGATCAATCCGGAGACGACGATCTACGCGCCGATCGCCGGCACGGTGGTGCAGCGC
AAGATCGGCCCCGGGCAATACGTCAATGCCGGCGCCAGCGATCCGGTGTTCGTGATCGGTGACCTGTCGACGGTGTGGCT
CACCGCCTTCGTCCGCGAGTCCGAGGCTGCCGACGTCGAGGTCGGCCAGGACATCAGCTTCCAGGTGCTGGCACTGCCCG
GCCGCACGCTGACCGGCCGCATCAACTACGTCGCCGCCGCGATCGACCCCGCCACGCGCCGGCTGATGGTTCGCGCCACC
ATGGACAATCCCGACGGCGCGCTGAAGCCGGAAATGTTCGCCAATGTCACGATCTACTCGGCGTCCGACCACCCCGCAGT
CGGCGTGCCGCGCACGGCGCTGATCTACGAGGGCGACCAGGTCCGGGTCTGGGTCGCGCGCGACGACCGCTCGATCGAGC
TGCGCACCATCAAGCCGGGGCTCACCGCGGGCAATCTGGTCGAAGTGATCGGCAATCTGCAGCCGGGCGAAAAGATCGTC
ACCAAGGGCGCCCTGTTCATCGATCGCGCGGCGACCGGTTGA

Upstream 100 bases:

>100_bases
CCGCAGAAACTCATCCCGGCTGACGCCGGTCCGCCTTTGTGGTTAGCGTGTCATGGTTCGGCACTATCAGTCGCCCGGAG
GCAATGCGGTGATCAAGCCC

Downstream 100 bases:

>100_bases
GGTTCGCAGGCGCTGCCCGCGTGAAGATACGCCGCCGCCTTCCTTCTACTCCTTCCTTGCCCGTTCTCTCCGATTTCTCG
CCTGCGACGTGATCTTCCGG

Product: secretion protein HlyD

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 413; Mature: 413

Protein sequence:

>413_residues
MWKHVTRRLRRVTRKRLVLTGCLVVGVAVAGSIVADRYAATEVHSEISSQSRRSADRYTPSAAEWASLTIEKVSDFSFRA
EHVTEGKIAIDEDRSTPVFSPYAGRVTKLLARPGDHVVQGQPLFTIEAPDTVQAQNDFIVASTALNKAKSQLELAQFQDK
RARDLFDGKAVPLKDYQQAQATLTSAQNDMQSATTALEAARNRLRILGLTESAITAFQDKGRINPETTIYAPIAGTVVQR
KIGPGQYVNAGASDPVFVIGDLSTVWLTAFVRESEAADVEVGQDISFQVLALPGRTLTGRINYVAAAIDPATRRLMVRAT
MDNPDGALKPEMFANVTIYSASDHPAVGVPRTALIYEGDQVRVWVARDDRSIELRTIKPGLTAGNLVEVIGNLQPGEKIV
TKGALFIDRAATG

Sequences:

>Translated_413_residues
MWKHVTRRLRRVTRKRLVLTGCLVVGVAVAGSIVADRYAATEVHSEISSQSRRSADRYTPSAAEWASLTIEKVSDFSFRA
EHVTEGKIAIDEDRSTPVFSPYAGRVTKLLARPGDHVVQGQPLFTIEAPDTVQAQNDFIVASTALNKAKSQLELAQFQDK
RARDLFDGKAVPLKDYQQAQATLTSAQNDMQSATTALEAARNRLRILGLTESAITAFQDKGRINPETTIYAPIAGTVVQR
KIGPGQYVNAGASDPVFVIGDLSTVWLTAFVRESEAADVEVGQDISFQVLALPGRTLTGRINYVAAAIDPATRRLMVRAT
MDNPDGALKPEMFANVTIYSASDHPAVGVPRTALIYEGDQVRVWVARDDRSIELRTIKPGLTAGNLVEVIGNLQPGEKIV
TKGALFIDRAATG
>Mature_413_residues
MWKHVTRRLRRVTRKRLVLTGCLVVGVAVAGSIVADRYAATEVHSEISSQSRRSADRYTPSAAEWASLTIEKVSDFSFRA
EHVTEGKIAIDEDRSTPVFSPYAGRVTKLLARPGDHVVQGQPLFTIEAPDTVQAQNDFIVASTALNKAKSQLELAQFQDK
RARDLFDGKAVPLKDYQQAQATLTSAQNDMQSATTALEAARNRLRILGLTESAITAFQDKGRINPETTIYAPIAGTVVQR
KIGPGQYVNAGASDPVFVIGDLSTVWLTAFVRESEAADVEVGQDISFQVLALPGRTLTGRINYVAAAIDPATRRLMVRAT
MDNPDGALKPEMFANVTIYSASDHPAVGVPRTALIYEGDQVRVWVARDDRSIELRTIKPGLTAGNLVEVIGNLQPGEKIV
TKGALFIDRAATG

Specific function: CzcA and CzcB together would act in zinc efflux nearly as effectively as the complete czc efflux system (CzcABC). The CzcB protein is thought to funnel zinc cations to the CzcA transport protein [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family [H]

Homologues:

Organism=Escherichia coli, GI1786787, Length=298, Percent_Identity=26.510067114094, Blast_Score=84, Evalue=2e-17,
Organism=Escherichia coli, GI87081796, Length=320, Percent_Identity=25.9375, Blast_Score=64, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005695
- InterPro:   IPR006143 [H]

Pfam domain/function: PF00529 HlyD [H]

EC number: NA

Molecular weight: Translated: 44856; Mature: 44856

Theoretical pI: Translated: 9.19; Mature: 9.19

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MWKHVTRRLRRVTRKRLVLTGCLVVGVAVAGSIVADRYAATEVHSEISSQSRRSADRYTP
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
SAAEWASLTIEKVSDFSFRAEHVTEGKIAIDEDRSTPVFSPYAGRVTKLLARPGDHVVQG
CCHHHHHEEHHHHCCCCEECCEECCCCEEEECCCCCCCCCCHHHHHHHHHHCCCCCEECC
QPLFTIEAPDTVQAQNDFIVASTALNKAKSQLELAQFQDKRARDLFDGKAVPLKDYQQAQ
CEEEEEECCCCEECCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHH
ATLTSAQNDMQSATTALEAARNRLRILGLTESAITAFQDKGRINPETTIYAPIAGTVVQR
HHHHHHHHHHHHHHHHHHHHHCCEEEEEECHHHHHHHHHCCCCCCCCEEEECCCCHHHHH
KIGPGQYVNAGASDPVFVIGDLSTVWLTAFVRESEAADVEVGQDISFQVLALPGRTLTGR
CCCCCCEECCCCCCCEEEEECHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEECCCEEEEE
INYVAAAIDPATRRLMVRATMDNPDGALKPEMFANVTIYSASDHPAVGVPRTALIYEGDQ
EEEEEEECCCCCEEEEEEEECCCCCCCCCCCCEEEEEEEECCCCCCCCCCCEEEEEECCE
VRVWVARDDRSIELRTIKPGLTAGNLVEVIGNLQPGEKIVTKGALFIDRAATG
EEEEEEECCCEEEEEEECCCCCCCHHHHHHCCCCCCHHHHHCCCEEEECCCCC
>Mature Secondary Structure
MWKHVTRRLRRVTRKRLVLTGCLVVGVAVAGSIVADRYAATEVHSEISSQSRRSADRYTP
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
SAAEWASLTIEKVSDFSFRAEHVTEGKIAIDEDRSTPVFSPYAGRVTKLLARPGDHVVQG
CCHHHHHEEHHHHCCCCEECCEECCCCEEEECCCCCCCCCCHHHHHHHHHHCCCCCEECC
QPLFTIEAPDTVQAQNDFIVASTALNKAKSQLELAQFQDKRARDLFDGKAVPLKDYQQAQ
CEEEEEECCCCEECCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHH
ATLTSAQNDMQSATTALEAARNRLRILGLTESAITAFQDKGRINPETTIYAPIAGTVVQR
HHHHHHHHHHHHHHHHHHHHHCCEEEEEECHHHHHHHHHCCCCCCCCEEEECCCCHHHHH
KIGPGQYVNAGASDPVFVIGDLSTVWLTAFVRESEAADVEVGQDISFQVLALPGRTLTGR
CCCCCCEECCCCCCCEEEEECHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEECCCEEEEE
INYVAAAIDPATRRLMVRATMDNPDGALKPEMFANVTIYSASDHPAVGVPRTALIYEGDQ
EEEEEEECCCCCEEEEEEEECCCCCCCCCCCCEEEEEEEECCCCCCCCCCCEEEEEECCE
VRVWVARDDRSIELRTIKPGLTAGNLVEVIGNLQPGEKIVTKGALFIDRAATG
EEEEEEECCCEEEEEEECCCCCCCHHHHHHCCCCCCHHHHHCCCEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8829543 [H]