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The map label for this gene is sgbE [C]

Identifier: 86750631

GI number: 86750631

Start: 4029350

End: 4030129

Strand: Direct

Name: sgbE [C]

Synonym: RPB_3521

Alternate gene names: 86750631

Gene position: 4029350-4030129 (Clockwise)

Preceding gene: 86750627

Following gene: 86750632

Centisome position: 75.57

GC content: 64.74

Gene sequence:

>780_bases
ATGTCGCCAGCGGAAGCACGCCTGAGAGAAGTCCCGTCGGATATGACCGAGGCCGAATGGGAGCAGCGGGTCAATCTCGC
CGCCTGCTATCGCCTCGTCGCCTATTACGGCTGGGACGATCTGGTCGACACCCACATTTCGGCGCGGGTGCCCGGGCCGG
AGCATCACTTCCTGATCAATCCCTACGGCCTGATGTTCGACGAGATCACGGCGTCGAGCCTGGTCAAGGTCGACCTCGAC
GGCAACCAGCTCACCCAGAGCCAGTACAAGATCAACCCGGCCGGCTTCACCATCCATTCGGCGGTCCACGAAGTCCGCGA
GGACGCCGGCTGCGTGATGCATCTGCATACGCCGGACGGCACCGCGGTGGCGAGCTGTCAGGAGGGCCTGCTGCCGCTGA
ACCAGACCGCGCATTTCGTCACCGGCGACCTCGCCTATCACGACTACGAAGGCGTCGCGCTGGATCACGACGAGCGCCCG
CGGCTGCAGCGCGACCTCGGCAAGAAGAACCACATGCTGCTGCGCAATCACGGCACACTGACGGTGGGCCGTTCGGTCGC
CTCCGCCTTCGAGCGGATGTACCACCTCGAGCGCGCCTGCACGATGCAGGTCCGCACAAGGATGCTGGGCCCGACCGCCT
ATCCGGTCGAGAACGTGGTGATCGACAAGAACCACAATCTGATCGCCAACCAGGACGCGATGGAGCTGCGCTCCACCAAG
CTGGTCTGGCCGCCGCTGCTGCGCAAGCTCGACCGCATCGACCCGAGCTATCGCAACTGA

Upstream 100 bases:

>100_bases
CTGCGCGTGCTGCGACTTGCTGCGACGCATTCGCACGACTAACCTCAGCCCCAATCATCGCGCCATCGAGCAACAGCAAC
GCGCAATCAGAGGGAACGCC

Downstream 100 bases:

>100_bases
GAACGCGCGGAGCGGTTGAAAACCCGCCGCGGCCGATGTAGACTTAAGTCACACCCCTCTACGCGATCGACGACAAACGC
CGCCCAATTCCGGGCGGCGT

Product: aldolase II superfamily protein

Products: xylulose-5-phosphate [C]

Alternate protein names: NA

Number of amino acids: Translated: 259; Mature: 258

Protein sequence:

>259_residues
MSPAEARLREVPSDMTEAEWEQRVNLAACYRLVAYYGWDDLVDTHISARVPGPEHHFLINPYGLMFDEITASSLVKVDLD
GNQLTQSQYKINPAGFTIHSAVHEVREDAGCVMHLHTPDGTAVASCQEGLLPLNQTAHFVTGDLAYHDYEGVALDHDERP
RLQRDLGKKNHMLLRNHGTLTVGRSVASAFERMYHLERACTMQVRTRMLGPTAYPVENVVIDKNHNLIANQDAMELRSTK
LVWPPLLRKLDRIDPSYRN

Sequences:

>Translated_259_residues
MSPAEARLREVPSDMTEAEWEQRVNLAACYRLVAYYGWDDLVDTHISARVPGPEHHFLINPYGLMFDEITASSLVKVDLD
GNQLTQSQYKINPAGFTIHSAVHEVREDAGCVMHLHTPDGTAVASCQEGLLPLNQTAHFVTGDLAYHDYEGVALDHDERP
RLQRDLGKKNHMLLRNHGTLTVGRSVASAFERMYHLERACTMQVRTRMLGPTAYPVENVVIDKNHNLIANQDAMELRSTK
LVWPPLLRKLDRIDPSYRN
>Mature_258_residues
SPAEARLREVPSDMTEAEWEQRVNLAACYRLVAYYGWDDLVDTHISARVPGPEHHFLINPYGLMFDEITASSLVKVDLDG
NQLTQSQYKINPAGFTIHSAVHEVREDAGCVMHLHTPDGTAVASCQEGLLPLNQTAHFVTGDLAYHDYEGVALDHDERPR
LQRDLGKKNHMLLRNHGTLTVGRSVASAFERMYHLERACTMQVRTRMLGPTAYPVENVVIDKNHNLIANQDAMELRSTKL
VWPPLLRKLDRIDPSYRN

Specific function: Probable Pentulose-5-Phosphate-4-Epimerase. [C]

COG id: COG0235

COG function: function code G; Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aldolase class II family [H]

Homologues:

Organism=Homo sapiens, GI29826323, Length=187, Percent_Identity=46.524064171123, Blast_Score=179, Evalue=3e-45,
Organism=Homo sapiens, GI29826325, Length=187, Percent_Identity=46.524064171123, Blast_Score=179, Evalue=3e-45,
Organism=Homo sapiens, GI29826321, Length=187, Percent_Identity=46.524064171123, Blast_Score=179, Evalue=3e-45,
Organism=Homo sapiens, GI29826319, Length=187, Percent_Identity=46.524064171123, Blast_Score=178, Evalue=3e-45,
Organism=Homo sapiens, GI9257190, Length=211, Percent_Identity=38.3886255924171, Blast_Score=156, Evalue=1e-38,
Organism=Homo sapiens, GI297307160, Length=211, Percent_Identity=38.3886255924171, Blast_Score=156, Evalue=1e-38,
Organism=Homo sapiens, GI89276787, Length=211, Percent_Identity=38.3886255924171, Blast_Score=156, Evalue=1e-38,
Organism=Homo sapiens, GI297307158, Length=211, Percent_Identity=38.3886255924171, Blast_Score=156, Evalue=2e-38,
Organism=Homo sapiens, GI9257192, Length=211, Percent_Identity=38.3886255924171, Blast_Score=156, Evalue=2e-38,
Organism=Homo sapiens, GI9951927, Length=196, Percent_Identity=39.7959183673469, Blast_Score=152, Evalue=4e-37,
Organism=Homo sapiens, GI62912453, Length=196, Percent_Identity=39.7959183673469, Blast_Score=152, Evalue=4e-37,
Organism=Homo sapiens, GI9943848, Length=196, Percent_Identity=39.7959183673469, Blast_Score=152, Evalue=4e-37,
Organism=Caenorhabditis elegans, GI115533216, Length=250, Percent_Identity=37.6, Blast_Score=172, Evalue=1e-43,
Organism=Caenorhabditis elegans, GI115533218, Length=250, Percent_Identity=37.6, Blast_Score=172, Evalue=2e-43,
Organism=Caenorhabditis elegans, GI71989560, Length=250, Percent_Identity=32.8, Blast_Score=131, Evalue=3e-31,
Organism=Caenorhabditis elegans, GI71989541, Length=250, Percent_Identity=32.8, Blast_Score=131, Evalue=3e-31,
Organism=Caenorhabditis elegans, GI71989544, Length=250, Percent_Identity=32.8, Blast_Score=131, Evalue=3e-31,
Organism=Caenorhabditis elegans, GI71989550, Length=250, Percent_Identity=32.8, Blast_Score=131, Evalue=3e-31,
Organism=Caenorhabditis elegans, GI71989555, Length=250, Percent_Identity=32.8, Blast_Score=131, Evalue=3e-31,
Organism=Drosophila melanogaster, GI281363755, Length=191, Percent_Identity=38.7434554973822, Blast_Score=136, Evalue=2e-32,
Organism=Drosophila melanogaster, GI281363751, Length=191, Percent_Identity=38.7434554973822, Blast_Score=136, Evalue=2e-32,
Organism=Drosophila melanogaster, GI24655690, Length=191, Percent_Identity=38.7434554973822, Blast_Score=136, Evalue=2e-32,
Organism=Drosophila melanogaster, GI281363763, Length=191, Percent_Identity=38.7434554973822, Blast_Score=136, Evalue=2e-32,
Organism=Drosophila melanogaster, GI281363757, Length=191, Percent_Identity=38.7434554973822, Blast_Score=136, Evalue=2e-32,
Organism=Drosophila melanogaster, GI17136738, Length=191, Percent_Identity=38.7434554973822, Blast_Score=136, Evalue=2e-32,
Organism=Drosophila melanogaster, GI24655685, Length=191, Percent_Identity=38.7434554973822, Blast_Score=135, Evalue=2e-32,
Organism=Drosophila melanogaster, GI281363761, Length=191, Percent_Identity=38.7434554973822, Blast_Score=135, Evalue=3e-32,
Organism=Drosophila melanogaster, GI281363759, Length=191, Percent_Identity=38.7434554973822, Blast_Score=135, Evalue=3e-32,
Organism=Drosophila melanogaster, GI281363753, Length=191, Percent_Identity=38.7434554973822, Blast_Score=135, Evalue=3e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001303 [H]

Pfam domain/function: PF00596 Aldolase_II [H]

EC number: 5.1.-.- [C]

Molecular weight: Translated: 29323; Mature: 29191

Theoretical pI: Translated: 6.39; Mature: 6.39

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSPAEARLREVPSDMTEAEWEQRVNLAACYRLVAYYGWDDLVDTHISARVPGPEHHFLIN
CCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHEECCCCCCCEEEEC
PYGLMFDEITASSLVKVDLDGNQLTQSQYKINPAGFTIHSAVHEVREDAGCVMHLHTPDG
CHHHHHHHHCCCCEEEEECCCCCEECCCEEECCCCCHHHHHHHHHHHCCCEEEEEECCCC
TAVASCQEGLLPLNQTAHFVTGDLAYHDYEGVALDHDERPRLQRDLGKKNHMLLRNHGTL
CCHHHHHHCCCCCCCCCCEEECCEEEECCCCEEECCCCCCHHHHHCCCCCCEEEECCCCE
TVGRSVASAFERMYHLERACTMQVRTRMLGPTAYPVENVVIDKNHNLIANQDAMELRSTK
EEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCCEEECCHHHHHHHCC
LVWPPLLRKLDRIDPSYRN
CCCHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
SPAEARLREVPSDMTEAEWEQRVNLAACYRLVAYYGWDDLVDTHISARVPGPEHHFLIN
CCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHEECCCCCCCEEEEC
PYGLMFDEITASSLVKVDLDGNQLTQSQYKINPAGFTIHSAVHEVREDAGCVMHLHTPDG
CHHHHHHHHCCCCEEEEECCCCCEECCCEEECCCCCHHHHHHHHHHHCCCEEEEEECCCC
TAVASCQEGLLPLNQTAHFVTGDLAYHDYEGVALDHDERPRLQRDLGKKNHMLLRNHGTL
CCHHHHHHCCCCCCCCCCEEECCEEEECCCCEEECCCCCCHHHHHCCCCCCEEEECCCCE
TVGRSVASAFERMYHLERACTMQVRTRMLGPTAYPVENVVIDKNHNLIANQDAMELRSTK
EEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCCEEECCHHHHHHHCC
LVWPPLLRKLDRIDPSYRN
CCCHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: L-ribulose-5-phosphate [C]

Specific reaction: L-ribulose-5-phosphate = xylulose-5-phosphate [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]