Click here to switch to the map view.

The map label for this gene is degP [H]

Identifier: 86750554

GI number: 86750554

Start: 3948654

End: 3950240

Strand: Reverse

Name: degP [H]

Synonym: RPB_3443

Alternate gene names: 86750554

Gene position: 3950240-3948654 (Counterclockwise)

Preceding gene: 86750557

Following gene: 86750553

Centisome position: 74.09

GC content: 67.99

Gene sequence:

>1587_bases
ATGACCGACCGTTCTTCCGATCTCACCTCGCAGCCGACCAGCCCGGTGCGCCGTTCGCTGTTCTCGGCGCGCAAATTCGC
GCTGATGGCGTCGGTGGTGGCCGGCCTCGGCGCGGGCGCGTTCGGCCTGTCGCAGGTCCCGGCGTCGGGCGATCTGTTCA
GCACGGCGGCGCAGGCGCAGGTCGGCAACGAGGTCCACAAGGCGCAGCAGCCCGTCGGCTTCGCCGACATCGTCGAGAAG
GTGAAGCCCTCGGTGATCTCGGTGAAGGTCAACATCGCCGAAAAAGTTGCGAAGACCGACGAGCGCAGCGAGCGCAGCGA
AGAATCGCCGTTCGCGCCCGGCTCGCCGATGGAGCGCTTCTTCCGCCGCTTCGGCGGTGAAATGCCGCCCGGCATGCGCG
GCCATCGCGGCGGCGGCATGATGACGGGGCAGGGCTCGGGCTTCTTCATCACCGCCGACGGCTACGCCGTCACCAACAAT
CACGTCGTCGACGGCGCCGACAAGGTCGAAGTCACCACCGACGACGGCAAGACCTACAAGGCCAAGGTGATCGGCACCGA
CCAGCGCACCGATCTGGCGCTGATCAAAGCCGAAGGCCGCACCGACTTCCCGTTCGCCAAGCTGTCCGAAGGCAAGCCGC
GGATCGGCGACTGGGTGCTCGCGGTCGGCAATCCGTTCGGCCTCGGCGGCACCGTCACCGCCGGCATCGTCTCGGCCTCC
GGCCGCGACCTCGGCAACGGTCCGTATGACGATTTCATCCAGATCGACGCGCCGGTGAACAAAGGCAATTCCGGCGGTCC
GGCGTTCGACGTCAATGGCGAAGTGATGGGTGTCAACACGGCGATCTACTCGCCGTCGGGCGGCAGCGTCGGCATCGCGT
TCTCGATCCCGGCCTCGACCGTCAAGGCGGTGGTGCAGCAGCTCAAGGACAAGGGCTCCGTCAGCCGTGGCTGGATCGGC
GTCCAGATCCAGCCGGTGACGCCGGAGATCGCCGACAGCCTCGGGCTGAAGAAGCCGGACGGCGCGTTGGTGGCCGAGCC
GCAGCCCAACGGCCCGGCCGCCAAGGCCGGCATCGAATCCGGCGACGTCATCACCGCGGTCAACGGCGCGCCGGTGAAGG
ACGCGCGCGAGCTCGCCCGCACCATCGGCGGCTTCGCGCCGGGCAATACGGTGAAGCTCACCGTGTTCCACAAGGGCGCG
GATCGGGAACTCAGCCTGACGCTCGGCCAATTGCCGAACCAGGTCGAGGCCAAGGCCAATCTCGACGGCGACAACGGTCG
CCAATCCAGCCGCGGCACCGAAGTGCCGAGGCTCGGCCTGACGGTCGCGCCGGCCAGTTCGGTCGCCGGTGCCGGCAAGG
ATGGCGTGGTGGTCACCGACGTCGATCCGAAGAGCGCCGCAGCCGATCGCGGCTTCAAGGAAGGCGACGTGATCCTCGAG
GTCGCGGGCAAGAACGTGGCGAGCCCGGGTGACGTCCGCGACGCCATCAACACCGCCAAGAACGACAACAAGAACAGCGT
GCTGATCCGGGTCCGCTCGGGTGGTTCGTCACGTTTCGTCGCGGTGCCGATCTCGGCCAAGGGCTGA

Upstream 100 bases:

>100_bases
AATGCCTCATCCAGCGCGCCGTAAGGCGGCAGCCCCCATCTTCAGGCCATCCGGTGCGATCGTCCGCACCCCTGACATTC
GATGGTTCTGGAGACCCTGT

Downstream 100 bases:

>100_bases
TCGGCCACCTGACGCCAAGTTGGAGAGTGTCGCCGGCAATGTCGCCCCCGCTGACGGCGCTTTCCGGGGGACGGGTGAAC
AGCTCGTCCCCACCTTCTAC

Product: peptidase S1C, Do

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 528; Mature: 527

Protein sequence:

>528_residues
MTDRSSDLTSQPTSPVRRSLFSARKFALMASVVAGLGAGAFGLSQVPASGDLFSTAAQAQVGNEVHKAQQPVGFADIVEK
VKPSVISVKVNIAEKVAKTDERSERSEESPFAPGSPMERFFRRFGGEMPPGMRGHRGGGMMTGQGSGFFITADGYAVTNN
HVVDGADKVEVTTDDGKTYKAKVIGTDQRTDLALIKAEGRTDFPFAKLSEGKPRIGDWVLAVGNPFGLGGTVTAGIVSAS
GRDLGNGPYDDFIQIDAPVNKGNSGGPAFDVNGEVMGVNTAIYSPSGGSVGIAFSIPASTVKAVVQQLKDKGSVSRGWIG
VQIQPVTPEIADSLGLKKPDGALVAEPQPNGPAAKAGIESGDVITAVNGAPVKDARELARTIGGFAPGNTVKLTVFHKGA
DRELSLTLGQLPNQVEAKANLDGDNGRQSSRGTEVPRLGLTVAPASSVAGAGKDGVVVTDVDPKSAAADRGFKEGDVILE
VAGKNVASPGDVRDAINTAKNDNKNSVLIRVRSGGSSRFVAVPISAKG

Sequences:

>Translated_528_residues
MTDRSSDLTSQPTSPVRRSLFSARKFALMASVVAGLGAGAFGLSQVPASGDLFSTAAQAQVGNEVHKAQQPVGFADIVEK
VKPSVISVKVNIAEKVAKTDERSERSEESPFAPGSPMERFFRRFGGEMPPGMRGHRGGGMMTGQGSGFFITADGYAVTNN
HVVDGADKVEVTTDDGKTYKAKVIGTDQRTDLALIKAEGRTDFPFAKLSEGKPRIGDWVLAVGNPFGLGGTVTAGIVSAS
GRDLGNGPYDDFIQIDAPVNKGNSGGPAFDVNGEVMGVNTAIYSPSGGSVGIAFSIPASTVKAVVQQLKDKGSVSRGWIG
VQIQPVTPEIADSLGLKKPDGALVAEPQPNGPAAKAGIESGDVITAVNGAPVKDARELARTIGGFAPGNTVKLTVFHKGA
DRELSLTLGQLPNQVEAKANLDGDNGRQSSRGTEVPRLGLTVAPASSVAGAGKDGVVVTDVDPKSAAADRGFKEGDVILE
VAGKNVASPGDVRDAINTAKNDNKNSVLIRVRSGGSSRFVAVPISAKG
>Mature_527_residues
TDRSSDLTSQPTSPVRRSLFSARKFALMASVVAGLGAGAFGLSQVPASGDLFSTAAQAQVGNEVHKAQQPVGFADIVEKV
KPSVISVKVNIAEKVAKTDERSERSEESPFAPGSPMERFFRRFGGEMPPGMRGHRGGGMMTGQGSGFFITADGYAVTNNH
VVDGADKVEVTTDDGKTYKAKVIGTDQRTDLALIKAEGRTDFPFAKLSEGKPRIGDWVLAVGNPFGLGGTVTAGIVSASG
RDLGNGPYDDFIQIDAPVNKGNSGGPAFDVNGEVMGVNTAIYSPSGGSVGIAFSIPASTVKAVVQQLKDKGSVSRGWIGV
QIQPVTPEIADSLGLKKPDGALVAEPQPNGPAAKAGIESGDVITAVNGAPVKDARELARTIGGFAPGNTVKLTVFHKGAD
RELSLTLGQLPNQVEAKANLDGDNGRQSSRGTEVPRLGLTVAPASSVAGAGKDGVVVTDVDPKSAAADRGFKEGDVILEV
AGKNVASPGDVRDAINTAKNDNKNSVLIRVRSGGSSRFVAVPISAKG

Specific function: Serine Protease That Is Required At High Temperature. Involved In The Degradation Of Damaged Proteins. It Can Degrade Icia, Ada, Casein And Globin. Shared Specificity With Degq. [C]

COG id: COG0265

COG function: function code O; Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain

Gene ontology:

Cell location: Periplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 PDZ (DHR) domains [H]

Homologues:

Organism=Homo sapiens, GI22129776, Length=335, Percent_Identity=31.9402985074627, Blast_Score=160, Evalue=3e-39,
Organism=Homo sapiens, GI4506141, Length=256, Percent_Identity=37.5, Blast_Score=155, Evalue=1e-37,
Organism=Homo sapiens, GI24308541, Length=254, Percent_Identity=34.251968503937, Blast_Score=144, Evalue=1e-34,
Organism=Homo sapiens, GI7019477, Length=326, Percent_Identity=31.2883435582822, Blast_Score=130, Evalue=2e-30,
Organism=Escherichia coli, GI1786356, Length=468, Percent_Identity=36.965811965812, Blast_Score=253, Evalue=3e-68,
Organism=Escherichia coli, GI1789629, Length=429, Percent_Identity=35.8974358974359, Blast_Score=232, Evalue=5e-62,
Organism=Escherichia coli, GI1789630, Length=274, Percent_Identity=36.4963503649635, Blast_Score=175, Evalue=7e-45,
Organism=Drosophila melanogaster, GI24646839, Length=265, Percent_Identity=30.5660377358491, Blast_Score=120, Evalue=2e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001478
- InterPro:   IPR009003
- InterPro:   IPR011782
- InterPro:   IPR001254
- InterPro:   IPR001940 [H]

Pfam domain/function: PF00595 PDZ; PF00089 Trypsin [H]

EC number: 3.4.21.- [C]

Molecular weight: Translated: 54359; Mature: 54227

Theoretical pI: Translated: 9.19; Mature: 9.19

Prosite motif: PS50106 PDZ

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDRSSDLTSQPTSPVRRSLFSARKFALMASVVAGLGAGAFGLSQVPASGDLFSTAAQAQ
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHH
VGNEVHKAQQPVGFADIVEKVKPSVISVKVNIAEKVAKTDERSERSEESPFAPGSPMERF
HHHHHHHHHCCCCHHHHHHHHCCCEEEEEEEHHHHHHHHHHHHHHCCCCCCCCCCHHHHH
FRRFGGEMPPGMRGHRGGGMMTGQGSGFFITADGYAVTNNHVVDGADKVEVTTDDGKTYK
HHHHCCCCCCCCCCCCCCCEEECCCCEEEEEECCEEEECCEEECCCCEEEEECCCCCEEE
AKVIGTDQRTDLALIKAEGRTDFPFAKLSEGKPRIGDWVLAVGNPFGLGGTVTAGIVSAS
EEEEECCCCCCEEEEEECCCCCCCCHHCCCCCCCCCCEEEEECCCCCCCCCCEEEEEECC
GRDLGNGPYDDFIQIDAPVNKGNSGGPAFDVNGEVMGVNTAIYSPSGGSVGIAFSIPAST
CCCCCCCCCCCEEEEECCCCCCCCCCCEEECCCEEEEEEEEEECCCCCCEEEEEECCHHH
VKAVVQQLKDKGSVSRGWIGVQIQPVTPEIADSLGLKKPDGALVAEPQPNGPAAKAGIES
HHHHHHHHHHCCCCCCCEEEEEEEECCHHHHHHCCCCCCCCCEEECCCCCCCHHHCCCCC
GDVITAVNGAPVKDARELARTIGGFAPGNTVKLTVFHKGADRELSLTLGQLPNQVEAKAN
CCEEEEECCCCCHHHHHHHHHHCCCCCCCEEEEEEEECCCCCEEEEEHHCCCCCEEHEEC
LDGDNGRQSSRGTEVPRLGLTVAPASSVAGAGKDGVVVTDVDPKSAAADRGFKEGDVILE
CCCCCCCCCCCCCCCCCCCEEECCCHHHCCCCCCCEEEEECCCCHHHHHCCCCCCCEEEE
VAGKNVASPGDVRDAINTAKNDNKNSVLIRVRSGGSSRFVAVPISAKG
ECCCCCCCCCHHHHHHHHHCCCCCCEEEEEEECCCCCEEEEEEECCCC
>Mature Secondary Structure 
TDRSSDLTSQPTSPVRRSLFSARKFALMASVVAGLGAGAFGLSQVPASGDLFSTAAQAQ
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHH
VGNEVHKAQQPVGFADIVEKVKPSVISVKVNIAEKVAKTDERSERSEESPFAPGSPMERF
HHHHHHHHHCCCCHHHHHHHHCCCEEEEEEEHHHHHHHHHHHHHHCCCCCCCCCCHHHHH
FRRFGGEMPPGMRGHRGGGMMTGQGSGFFITADGYAVTNNHVVDGADKVEVTTDDGKTYK
HHHHCCCCCCCCCCCCCCCEEECCCCEEEEEECCEEEECCEEECCCCEEEEECCCCCEEE
AKVIGTDQRTDLALIKAEGRTDFPFAKLSEGKPRIGDWVLAVGNPFGLGGTVTAGIVSAS
EEEEECCCCCCEEEEEECCCCCCCCHHCCCCCCCCCCEEEEECCCCCCCCCCEEEEEECC
GRDLGNGPYDDFIQIDAPVNKGNSGGPAFDVNGEVMGVNTAIYSPSGGSVGIAFSIPAST
CCCCCCCCCCCEEEEECCCCCCCCCCCEEECCCEEEEEEEEEECCCCCCEEEEEECCHHH
VKAVVQQLKDKGSVSRGWIGVQIQPVTPEIADSLGLKKPDGALVAEPQPNGPAAKAGIES
HHHHHHHHHHCCCCCCCEEEEEEEECCHHHHHHCCCCCCCCCEEECCCCCCCHHHCCCCC
GDVITAVNGAPVKDARELARTIGGFAPGNTVKLTVFHKGADRELSLTLGQLPNQVEAKAN
CCEEEEECCCCCHHHHHHHHHHCCCCCCCEEEEEEEECCCCCEEEEEHHCCCCCEEHEEC
LDGDNGRQSSRGTEVPRLGLTVAPASSVAGAGKDGVVVTDVDPKSAAADRGFKEGDVILE
CCCCCCCCCCCCCCCCCCCEEECCCHHHCCCCCCCEEEEECCCCHHHHHCCCCCCCEEEE
VAGKNVASPGDVRDAINTAKNDNKNSVLIRVRSGGSSRFVAVPISAKG
ECCCCCCCCCHHHHHHHHHCCCCCCEEEEEEECCCCCEEEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: Serine endopeptidases [C]

General reaction: Hydrolase; Acting on peptide bonds (Peptidases) [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7861951 [H]