Click here to switch to the map view.

The map label for this gene is fprA [H]

Identifier: 86750525

GI number: 86750525

Start: 3901925

End: 3903262

Strand: Reverse

Name: fprA [H]

Synonym: RPB_3414

Alternate gene names: 86750525

Gene position: 3903262-3901925 (Counterclockwise)

Preceding gene: 86750526

Following gene: 86750522

Centisome position: 73.21

GC content: 66.37

Gene sequence:

>1338_bases
ATGACGGCAGCGGCGCGCGACCCTGCGCCCGCGGCTGCCTTTCGGATCGCGGTGGTCGGCAGCGGACCGAGCGGGTTCTA
CGCGACGGAGGCCTTGTTCCGGTCGGGCACGCCGGTCGCGGTCGATATGTTCGAGCAACTTCCGGTGCCCTATGGGCTGG
TGCGGTTCGGCGTCGCGCCCGACCATCCCAAGCTCAAACAGGTGACCGTCGCATTCGACCGGATCGCAACGATGCCGGGC
TTTCGATTCGTAGGCGGGGTCACCGTGGGGAGGGACGTGACGATCGATGAACTCCGCGCCAGCTACGACGCGGTGATCCT
CGCCACCGGTGCCGACGTCAGCCGTGCGCTGGGGATTCCGGGCGAAACGCTGGCTGGCTGTCATCACGCCGGTGATTTCG
TCGCCTGGTACAACGGTCATCCCGACTACCGCGATTGCTCGTTCGATCTCGCCCATGACGCGGTGACCATCGTCGGCCAT
GGCAACGTCGCCCTCGACGTCGCACGCATTCTGGCCCGCACTGTCGATGAGCTGCGCCTCACCGATATCGCCAGCCATGC
GCTCGAGGTGCTGGCTGAGAGCCGGGTCCGCGAGATCCATCTGGTCGGTCGCAGCGGGCCGCGGCAGGCGAAGTTCGGCG
CCAAGGAATTGCGGGATTTTCTCGCGCTGGCGCAGTGCGACGCTGTCGTCGATCCGCGTGATGTCGCCGCCGCTTCGGTA
GGTGAGACCTCGAACGATCCGGAGATGAGCGAGAAGCTGGAACTGCTCGGTGCAGTCTCGCAACGGCCTGTCGGCAAGCA
ACGGCGCTGCGTGTTTCGGTTCGGCCTCTCGCCTGTGGCGATCAATGGACGCGGCAGGGTCGAAGAGATCGCGTTTGCAG
ACCCGTCGCGGTCGATCGAAGCGATCCCGTGCGGTGTTGTTTTCAGCAGCATCGGCCGACGCACCGCGCCGTTGCCGGGC
GTGCCGTTCGATGCGCAACGCGGCGTGCACGCCAATGTCGACGGCCGCGTTGTGGACACTCACGGCGTCGTCCCCGGTCT
CTATGTCTGCGGCTGGAGCAAGCGCGGCCCGAGCGGTACGATCGGGACCAACCGGGCTTGTGGCATGGCCACCGCCGAGG
CGGTACTGACGGATTTGCCCGCGCGAGCGGGCTCTCGTTTGCGCGATCCCGATATTTTGCTGGCGCAGCTACGCGGTCGC
GTGTCTCGCATCGTCAGCTTCGACGATTGGAGCGCGATCGACGCGGCCGAGAAGAGCAGGGGCGTCGCTCAGGGCAGGCC
CCGCGAAAAATTCGTGTCCGTTCCCGAGATGATGGCGGTGCTGGCTTCAACGCCGTGA

Upstream 100 bases:

>100_bases
GGATCGACGTCAACCGCAAGCGTGCCGCTGAAACGCCGGTGCTCACCGCGCGGCTGCCGCCGCTGCCCGGCGCCGACGAC
CGCAGGCAGGCGCTGGGCCG

Downstream 100 bases:

>100_bases
ATGCCGCAGGCCTCGCGAACTACGCGCTGATGGCGTCCTCGGACGGCAGCTCTTCCGCCGCATTCGGATCGCCCGGCGCG
GTCGCCCAGGCGAGCTCGAC

Product: FAD-dependent pyridine nucleotide-disulphide oxidoreductase

Products: NA

Alternate protein names: NFR [H]

Number of amino acids: Translated: 445; Mature: 444

Protein sequence:

>445_residues
MTAAARDPAPAAAFRIAVVGSGPSGFYATEALFRSGTPVAVDMFEQLPVPYGLVRFGVAPDHPKLKQVTVAFDRIATMPG
FRFVGGVTVGRDVTIDELRASYDAVILATGADVSRALGIPGETLAGCHHAGDFVAWYNGHPDYRDCSFDLAHDAVTIVGH
GNVALDVARILARTVDELRLTDIASHALEVLAESRVREIHLVGRSGPRQAKFGAKELRDFLALAQCDAVVDPRDVAAASV
GETSNDPEMSEKLELLGAVSQRPVGKQRRCVFRFGLSPVAINGRGRVEEIAFADPSRSIEAIPCGVVFSSIGRRTAPLPG
VPFDAQRGVHANVDGRVVDTHGVVPGLYVCGWSKRGPSGTIGTNRACGMATAEAVLTDLPARAGSRLRDPDILLAQLRGR
VSRIVSFDDWSAIDAAEKSRGVAQGRPREKFVSVPEMMAVLASTP

Sequences:

>Translated_445_residues
MTAAARDPAPAAAFRIAVVGSGPSGFYATEALFRSGTPVAVDMFEQLPVPYGLVRFGVAPDHPKLKQVTVAFDRIATMPG
FRFVGGVTVGRDVTIDELRASYDAVILATGADVSRALGIPGETLAGCHHAGDFVAWYNGHPDYRDCSFDLAHDAVTIVGH
GNVALDVARILARTVDELRLTDIASHALEVLAESRVREIHLVGRSGPRQAKFGAKELRDFLALAQCDAVVDPRDVAAASV
GETSNDPEMSEKLELLGAVSQRPVGKQRRCVFRFGLSPVAINGRGRVEEIAFADPSRSIEAIPCGVVFSSIGRRTAPLPG
VPFDAQRGVHANVDGRVVDTHGVVPGLYVCGWSKRGPSGTIGTNRACGMATAEAVLTDLPARAGSRLRDPDILLAQLRGR
VSRIVSFDDWSAIDAAEKSRGVAQGRPREKFVSVPEMMAVLASTP
>Mature_444_residues
TAAARDPAPAAAFRIAVVGSGPSGFYATEALFRSGTPVAVDMFEQLPVPYGLVRFGVAPDHPKLKQVTVAFDRIATMPGF
RFVGGVTVGRDVTIDELRASYDAVILATGADVSRALGIPGETLAGCHHAGDFVAWYNGHPDYRDCSFDLAHDAVTIVGHG
NVALDVARILARTVDELRLTDIASHALEVLAESRVREIHLVGRSGPRQAKFGAKELRDFLALAQCDAVVDPRDVAAASVG
ETSNDPEMSEKLELLGAVSQRPVGKQRRCVFRFGLSPVAINGRGRVEEIAFADPSRSIEAIPCGVVFSSIGRRTAPLPGV
PFDAQRGVHANVDGRVVDTHGVVPGLYVCGWSKRGPSGTIGTNRACGMATAEAVLTDLPARAGSRLRDPDILLAQLRGRV
SRIVSFDDWSAIDAAEKSRGVAQGRPREKFVSVPEMMAVLASTP

Specific function: May serve as electron transfer protein and supply electrons to P450 systems [H]

COG id: COG0493

COG function: function code ER; NADPH-dependent glutamate synthase beta chain and related oxidoreductases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ferredoxin--NADP reductase type 1 family [H]

Homologues:

Organism=Homo sapiens, GI111118981, Length=458, Percent_Identity=41.9213973799127, Blast_Score=304, Evalue=9e-83,
Organism=Homo sapiens, GI111118983, Length=464, Percent_Identity=41.3793103448276, Blast_Score=298, Evalue=6e-81,
Organism=Escherichia coli, GI1789606, Length=164, Percent_Identity=31.7073170731707, Blast_Score=69, Evalue=8e-13,
Organism=Escherichia coli, GI87082180, Length=165, Percent_Identity=29.6969696969697, Blast_Score=64, Evalue=2e-11,
Organism=Escherichia coli, GI1788811, Length=164, Percent_Identity=29.8780487804878, Blast_Score=63, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI17543860, Length=436, Percent_Identity=34.4036697247706, Blast_Score=242, Evalue=4e-64,
Organism=Caenorhabditis elegans, GI17570289, Length=174, Percent_Identity=31.0344827586207, Blast_Score=67, Evalue=3e-11,
Organism=Saccharomyces cerevisiae, GI6320584, Length=479, Percent_Identity=30.062630480167, Blast_Score=208, Evalue=1e-54,
Organism=Drosophila melanogaster, GI17137178, Length=438, Percent_Identity=38.3561643835616, Blast_Score=279, Evalue=3e-75,
Organism=Drosophila melanogaster, GI24665547, Length=153, Percent_Identity=33.3333333333333, Blast_Score=69, Evalue=8e-12,
Organism=Drosophila melanogaster, GI24665543, Length=153, Percent_Identity=33.3333333333333, Blast_Score=69, Evalue=8e-12,
Organism=Drosophila melanogaster, GI28574881, Length=153, Percent_Identity=33.3333333333333, Blast_Score=69, Evalue=9e-12,
Organism=Drosophila melanogaster, GI24665539, Length=153, Percent_Identity=33.3333333333333, Blast_Score=69, Evalue=9e-12,

Paralogues:

None

Copy number: 620 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 180 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013027
- InterPro:   IPR021163
- InterPro:   IPR016040 [H]

Pfam domain/function: PF07992 Pyr_redox_2 [H]

EC number: =1.18.1.2 [H]

Molecular weight: Translated: 47263; Mature: 47132

Theoretical pI: Translated: 7.28; Mature: 7.28

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTAAARDPAPAAAFRIAVVGSGPSGFYATEALFRSGTPVAVDMFEQLPVPYGLVRFGVAP
CCCCCCCCCCCCEEEEEEEECCCCCHHHHHHHHHCCCCCEEHHHHHCCCCHHHHEECCCC
DHPKLKQVTVAFDRIATMPGFRFVGGVTVGRDVTIDELRASYDAVILATGADVSRALGIP
CCCCHHHHHHHHHHHHCCCCCEEECCEECCCCCCHHHHHCCCCEEEEEECCCHHHHCCCC
GETLAGCHHAGDFVAWYNGHPDYRDCSFDLAHDAVTIVGHGNVALDVARILARTVDELRL
CHHHHCCCCCCCEEEEECCCCCCCCCCEEECCCEEEEEECCCHHHHHHHHHHHHHHHHHH
TDIASHALEVLAESRVREIHLVGRSGPRQAKFGAKELRDFLALAQCDAVVDPRDVAAASV
HHHHHHHHHHHHHHHHEEEEEECCCCCCCHHCCHHHHHHHHHHHHHCCCCCCHHHHHHHC
GETSNDPEMSEKLELLGAVSQRPVGKQRRCVFRFGLSPVAINGRGRVEEIAFADPSRSIE
CCCCCCHHHHHHHHHHHHHHCCCCCCHHCEEEEECCCEEEECCCCCEEEEEECCCCCCCC
AIPCGVVFSSIGRRTAPLPGVPFDAQRGVHANVDGRVVDTHGVVPGLYVCGWSKRGPSGT
CCCHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCCCCEEEECCCCCCCCCC
IGTNRACGMATAEAVLTDLPARAGSRLRDPDILLAQLRGRVSRIVSFDDWSAIDAAEKSR
CCCCCCCCHHHHHHHHHHCCHHCCCCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHC
GVAQGRPREKFVSVPEMMAVLASTP
CCCCCCCHHHHHCHHHHHHHHHCCC
>Mature Secondary Structure 
TAAARDPAPAAAFRIAVVGSGPSGFYATEALFRSGTPVAVDMFEQLPVPYGLVRFGVAP
CCCCCCCCCCCEEEEEEEECCCCCHHHHHHHHHCCCCCEEHHHHHCCCCHHHHEECCCC
DHPKLKQVTVAFDRIATMPGFRFVGGVTVGRDVTIDELRASYDAVILATGADVSRALGIP
CCCCHHHHHHHHHHHHCCCCCEEECCEECCCCCCHHHHHCCCCEEEEEECCCHHHHCCCC
GETLAGCHHAGDFVAWYNGHPDYRDCSFDLAHDAVTIVGHGNVALDVARILARTVDELRL
CHHHHCCCCCCCEEEEECCCCCCCCCCEEECCCEEEEEECCCHHHHHHHHHHHHHHHHHH
TDIASHALEVLAESRVREIHLVGRSGPRQAKFGAKELRDFLALAQCDAVVDPRDVAAASV
HHHHHHHHHHHHHHHHEEEEEECCCCCCCHHCCHHHHHHHHHHHHHCCCCCCHHHHHHHC
GETSNDPEMSEKLELLGAVSQRPVGKQRRCVFRFGLSPVAINGRGRVEEIAFADPSRSIE
CCCCCCHHHHHHHHHHHHHHCCCCCCHHCEEEEECCCEEEECCCCCEEEEEECCCCCCCC
AIPCGVVFSSIGRRTAPLPGVPFDAQRGVHANVDGRVVDTHGVVPGLYVCGWSKRGPSGT
CCCHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCCCCEEEECCCCCCCCCC
IGTNRACGMATAEAVLTDLPARAGSRLRDPDILLAQLRGRVSRIVSFDDWSAIDAAEKSR
CCCCCCCCHHHHHHHHHHCCHHCCCCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHC
GVAQGRPREKFVSVPEMMAVLASTP
CCCCCCCHHHHHCHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036; 12071965; 12614197; 12102623 [H]