| Definition | Rhodopseudomonas palustris HaA2, complete genome. |
|---|---|
| Accession | NC_007778 |
| Length | 5,331,656 |
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The map label for this gene is fabG [C]
Identifier: 86750316
GI number: 86750316
Start: 3667108
End: 3668025
Strand: Reverse
Name: fabG [C]
Synonym: RPB_3205
Alternate gene names: 86750316
Gene position: 3668025-3667108 (Counterclockwise)
Preceding gene: 86750317
Following gene: 86750315
Centisome position: 68.8
GC content: 67.32
Gene sequence:
>918_bases ATGGCTATCAGGTTCGACGGACGCGTCGCCATCGTCACCGGCGCGGGCAACGGTTTGGGGCGCGCGCATGCGCTGGGCCT CGCGGCGCGCGGCGCCAAGGTGGTGGTCAACGATTTCGGCGGCGCGCGCGACGGCACCGGCGGCTCGATGACCGCGGCCG AGACGGTGGTCGAGGAGATCCGCAAGGCCGGCGGCACCGCGATGGCCGACGGCGCCGATGTCTCCAACTACGAGCAGGTG AAGGCGATGGTCGCGAAAGCGACCAAGGAGTGGGGCAGCGTCGATCTGATGGTGGCGAATGCCGGCATCCTGCGCGACAA ATCCTTCGGCAAGATGGAGCTCTCCGATTTCCAGAAGGTGATCGACGTGCATCTCGCCGGCACGTTCTACTGCTGCAAGG CGGTGTGGGACGGCATGAAGGAGCGCAACTACGGCCGCATCGTGCTGACCACCTCGTCGTCGGGCATGTTCGGCAATTTC GGCCAGGCCAATTACGGCGCGGCCAAAGCCGGCATCGTCGGGCTGATGAACGTGCTGGCGCAGGAGGGCCGCAAGACCGA CATCCGCGTCAACACCGTGTCGCCGACGGCCGCGACCCGGATGACCGAAGAGCTGCTGCCGCCGCAGGCGCTGCAATTGA TGAAGCCGGAGGCGATCACCCCGGCGGTGCTGTTCCTGCTCAGCGACAACGCGCCCACCCGCACCACGCTCGGCGCCGGC GCCGGCTCGTTCGCGCAGATCAAGATCATCGAGACCGAAGGCATCAACCTGCCGGAGGAGGAGTGGACCCCCGACGCGAT CGCCGCGCACTTCGCCGAGATCAGCGACGACTCCAAGGCGCAGGCGCTGGAAGGCGCATTCCAGCAGACGCAGAAATACG TCGCGCAGGCCGCGGCGAGGCTCGGCCTCAAGATGTGA
Upstream 100 bases:
>100_bases CCAGCGTCAACATCGAAATCGAGGGCGAGAAGCGCTCGGCGCTGGTCGCCGACTGGCTCGGCCTGATCTACTTCGAACAA TAATCCGGGAAACAACACAC
Downstream 100 bases:
>100_bases GGCCGACCTCTGTCGTCATTCCGGGGCGCGCGCAGCGCGAACCCGGAATCTCCGGTTGCAGAACATCTCGGGATTCCGGG TTCGCTCGCTGCGCGAGCGC
Product: short-chain dehydrogenase/reductase SDR
Products: (3R)-hydroxyacyl-[acyl-carrier-protein]; NADP; NADPH; Proton; beta-ketoacyl-ACP [C]
Alternate protein names: NA
Number of amino acids: Translated: 305; Mature: 304
Protein sequence:
>305_residues MAIRFDGRVAIVTGAGNGLGRAHALGLAARGAKVVVNDFGGARDGTGGSMTAAETVVEEIRKAGGTAMADGADVSNYEQV KAMVAKATKEWGSVDLMVANAGILRDKSFGKMELSDFQKVIDVHLAGTFYCCKAVWDGMKERNYGRIVLTTSSSGMFGNF GQANYGAAKAGIVGLMNVLAQEGRKTDIRVNTVSPTAATRMTEELLPPQALQLMKPEAITPAVLFLLSDNAPTRTTLGAG AGSFAQIKIIETEGINLPEEEWTPDAIAAHFAEISDDSKAQALEGAFQQTQKYVAQAAARLGLKM
Sequences:
>Translated_305_residues MAIRFDGRVAIVTGAGNGLGRAHALGLAARGAKVVVNDFGGARDGTGGSMTAAETVVEEIRKAGGTAMADGADVSNYEQV KAMVAKATKEWGSVDLMVANAGILRDKSFGKMELSDFQKVIDVHLAGTFYCCKAVWDGMKERNYGRIVLTTSSSGMFGNF GQANYGAAKAGIVGLMNVLAQEGRKTDIRVNTVSPTAATRMTEELLPPQALQLMKPEAITPAVLFLLSDNAPTRTTLGAG AGSFAQIKIIETEGINLPEEEWTPDAIAAHFAEISDDSKAQALEGAFQQTQKYVAQAAARLGLKM >Mature_304_residues AIRFDGRVAIVTGAGNGLGRAHALGLAARGAKVVVNDFGGARDGTGGSMTAAETVVEEIRKAGGTAMADGADVSNYEQVK AMVAKATKEWGSVDLMVANAGILRDKSFGKMELSDFQKVIDVHLAGTFYCCKAVWDGMKERNYGRIVLTTSSSGMFGNFG QANYGAAKAGIVGLMNVLAQEGRKTDIRVNTVSPTAATRMTEELLPPQALQLMKPEAITPAVLFLLSDNAPTRTTLGAGA GSFAQIKIIETEGINLPEEEWTPDAIAAHFAEISDDSKAQALEGAFQQTQKYVAQAAARLGLKM
Specific function: Fatty acid biosynthesis pathway; first reduction step. [C]
COG id: NA
COG function: NA
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]
Homologues:
Organism=Homo sapiens, GI4504505, Length=288, Percent_Identity=45.1388888888889, Blast_Score=242, Evalue=3e-64, Organism=Homo sapiens, GI15277342, Length=258, Percent_Identity=32.9457364341085, Blast_Score=94, Evalue=2e-19, Organism=Homo sapiens, GI4503817, Length=225, Percent_Identity=27.1111111111111, Blast_Score=87, Evalue=2e-17, Organism=Homo sapiens, GI4758504, Length=201, Percent_Identity=33.8308457711443, Blast_Score=84, Evalue=2e-16, Organism=Homo sapiens, GI40254992, Length=228, Percent_Identity=31.5789473684211, Blast_Score=84, Evalue=2e-16, Organism=Homo sapiens, GI109715829, Length=250, Percent_Identity=30.8, Blast_Score=83, Evalue=4e-16, Organism=Homo sapiens, GI210032110, Length=192, Percent_Identity=31.7708333333333, Blast_Score=82, Evalue=4e-16, Organism=Homo sapiens, GI25282469, Length=262, Percent_Identity=27.0992366412214, Blast_Score=79, Evalue=8e-15, Organism=Homo sapiens, GI83715985, Length=188, Percent_Identity=33.5106382978723, Blast_Score=76, Evalue=4e-14, Organism=Homo sapiens, GI40807363, Length=229, Percent_Identity=29.6943231441048, Blast_Score=75, Evalue=9e-14, Organism=Homo sapiens, GI310128830, Length=199, Percent_Identity=28.1407035175879, Blast_Score=69, Evalue=4e-12, Organism=Homo sapiens, GI310115468, Length=199, Percent_Identity=28.1407035175879, Blast_Score=69, Evalue=4e-12, Organism=Homo sapiens, GI32483357, Length=257, Percent_Identity=27.6264591439689, Blast_Score=68, Evalue=1e-11, Organism=Homo sapiens, GI19923817, Length=246, Percent_Identity=26.8292682926829, Blast_Score=66, Evalue=3e-11, Organism=Homo sapiens, GI142976729, Length=176, Percent_Identity=27.2727272727273, Blast_Score=66, Evalue=3e-11, Organism=Escherichia coli, GI1787335, Length=239, Percent_Identity=37.6569037656904, Blast_Score=126, Evalue=2e-30, Organism=Escherichia coli, GI1787905, Length=238, Percent_Identity=32.3529411764706, Blast_Score=94, Evalue=1e-20, Organism=Escherichia coli, GI87082100, Length=193, Percent_Identity=33.160621761658, Blast_Score=94, Evalue=1e-20, Organism=Escherichia coli, GI1789208, Length=206, Percent_Identity=27.6699029126214, Blast_Score=88, Evalue=5e-19, Organism=Escherichia coli, GI1790717, Length=206, Percent_Identity=28.6407766990291, Blast_Score=87, Evalue=1e-18, Organism=Escherichia coli, GI1789057, Length=237, Percent_Identity=31.2236286919831, Blast_Score=87, Evalue=2e-18, Organism=Escherichia coli, GI2367175, Length=243, Percent_Identity=30.8641975308642, Blast_Score=77, Evalue=1e-15, Organism=Escherichia coli, GI1787526, Length=234, Percent_Identity=26.9230769230769, Blast_Score=70, Evalue=1e-13, Organism=Escherichia coli, GI1787820, Length=188, Percent_Identity=28.7234042553192, Blast_Score=70, Evalue=1e-13, Organism=Escherichia coli, GI87082160, Length=206, Percent_Identity=28.6407766990291, Blast_Score=69, Evalue=3e-13, Organism=Escherichia coli, GI1788459, Length=200, Percent_Identity=30.5, Blast_Score=65, Evalue=4e-12, Organism=Escherichia coli, GI1786812, Length=247, Percent_Identity=25.9109311740891, Blast_Score=63, Evalue=2e-11, Organism=Caenorhabditis elegans, GI17568967, Length=299, Percent_Identity=42.4749163879599, Blast_Score=239, Evalue=1e-63, Organism=Caenorhabditis elegans, GI25147288, Length=241, Percent_Identity=32.3651452282158, Blast_Score=106, Evalue=2e-23, Organism=Caenorhabditis elegans, GI17555706, Length=236, Percent_Identity=31.7796610169492, Blast_Score=95, Evalue=5e-20, Organism=Caenorhabditis elegans, GI17564282, Length=196, Percent_Identity=33.1632653061224, Blast_Score=87, Evalue=1e-17, Organism=Caenorhabditis elegans, GI193203117, Length=237, Percent_Identity=29.1139240506329, Blast_Score=87, Evalue=1e-17, Organism=Caenorhabditis elegans, GI193203115, Length=274, Percent_Identity=28.4671532846715, Blast_Score=85, Evalue=5e-17, Organism=Caenorhabditis elegans, GI17567345, Length=197, Percent_Identity=31.9796954314721, Blast_Score=81, Evalue=6e-16, Organism=Caenorhabditis elegans, GI17538182, Length=201, Percent_Identity=34.3283582089552, Blast_Score=76, Evalue=2e-14, Organism=Caenorhabditis elegans, GI17561402, Length=251, Percent_Identity=29.4820717131474, Blast_Score=75, Evalue=3e-14, Organism=Caenorhabditis elegans, GI17508895, Length=189, Percent_Identity=27.5132275132275, Blast_Score=75, Evalue=4e-14, Organism=Caenorhabditis elegans, GI71982365, Length=199, Percent_Identity=31.6582914572864, Blast_Score=72, Evalue=4e-13, Organism=Caenorhabditis elegans, GI193204405, Length=225, Percent_Identity=29.3333333333333, Blast_Score=69, Evalue=4e-12, Organism=Caenorhabditis elegans, GI17562910, Length=200, Percent_Identity=30, Blast_Score=67, Evalue=2e-11, Organism=Saccharomyces cerevisiae, GI6322861, Length=277, Percent_Identity=45.8483754512635, Blast_Score=247, Evalue=2e-66, Organism=Saccharomyces cerevisiae, GI6324126, Length=193, Percent_Identity=29.0155440414508, Blast_Score=73, Evalue=6e-14, Organism=Drosophila melanogaster, GI18859837, Length=285, Percent_Identity=44.9122807017544, Blast_Score=236, Evalue=1e-62, Organism=Drosophila melanogaster, GI24639444, Length=235, Percent_Identity=34.8936170212766, Blast_Score=102, Evalue=4e-22, Organism=Drosophila melanogaster, GI24649181, Length=194, Percent_Identity=33.5051546391753, Blast_Score=94, Evalue=8e-20, Organism=Drosophila melanogaster, GI281364892, Length=193, Percent_Identity=28.4974093264249, Blast_Score=86, Evalue=2e-17, Organism=Drosophila melanogaster, GI24640492, Length=194, Percent_Identity=27.8350515463918, Blast_Score=85, Evalue=7e-17, Organism=Drosophila melanogaster, GI21355631, Length=181, Percent_Identity=32.5966850828729, Blast_Score=80, Evalue=2e-15, Organism=Drosophila melanogaster, GI17737361, Length=199, Percent_Identity=32.1608040201005, Blast_Score=80, Evalue=2e-15, Organism=Drosophila melanogaster, GI21356301, Length=230, Percent_Identity=27.3913043478261, Blast_Score=77, Evalue=1e-14, Organism=Drosophila melanogaster, GI116007236, Length=240, Percent_Identity=27.9166666666667, Blast_Score=77, Evalue=1e-14, Organism=Drosophila melanogaster, GI24581726, Length=217, Percent_Identity=25.8064516129032, Blast_Score=77, Evalue=2e-14, Organism=Drosophila melanogaster, GI24648693, Length=241, Percent_Identity=29.4605809128631, Blast_Score=75, Evalue=5e-14, Organism=Drosophila melanogaster, GI21355889, Length=241, Percent_Identity=29.4605809128631, Blast_Score=75, Evalue=5e-14, Organism=Drosophila melanogaster, GI21357673, Length=258, Percent_Identity=27.5193798449612, Blast_Score=72, Evalue=4e-13, Organism=Drosophila melanogaster, GI116007234, Length=241, Percent_Identity=28.2157676348548, Blast_Score=71, Evalue=1e-12, Organism=Drosophila melanogaster, GI21357041, Length=192, Percent_Identity=27.6041666666667, Blast_Score=67, Evalue=1e-11, Organism=Drosophila melanogaster, GI23397609, Length=196, Percent_Identity=28.5714285714286, Blast_Score=66, Evalue=4e-11,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR002198 - InterPro: IPR002347 - InterPro: IPR016040 - InterPro: IPR020904 [H]
Pfam domain/function: PF00106 adh_short [H]
EC number: 1.1.1.100 [C]
Molecular weight: Translated: 32093; Mature: 31962
Theoretical pI: Translated: 6.30; Mature: 6.30
Prosite motif: PS00061 ADH_SHORT
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.7 %Cys (Translated Protein) 3.9 %Met (Translated Protein) 4.6 %Cys+Met (Translated Protein) 0.7 %Cys (Mature Protein) 3.6 %Met (Mature Protein) 4.3 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MAIRFDGRVAIVTGAGNGLGRAHALGLAARGAKVVVNDFGGARDGTGGSMTAAETVVEEI CEEEECCEEEEEEECCCCCCHHHHHHHHCCCCEEEEECCCCCCCCCCCCHHHHHHHHHHH RKAGGTAMADGADVSNYEQVKAMVAKATKEWGSVDLMVANAGILRDKSFGKMELSDFQKV HHCCCCEECCCCCCCHHHHHHHHHHHHHHCCCCEEEEEECCCEEECCCCCCCCHHHHHHH IDVHLAGTFYCCKAVWDGMKERNYGRIVLTTSSSGMFGNFGQANYGAAKAGIVGLMNVLA HHHHHHHHHHHHHHHHCCHHHCCCCEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHH QEGRKTDIRVNTVSPTAATRMTEELLPPQALQLMKPEAITPAVLFLLSDNAPTRTTLGAG HCCCCCEEEEEECCCHHHHHHHHHHCCHHHHHHCCCCCCCCEEEEEECCCCCCCEEECCC AGSFAQIKIIETEGINLPEEEWTPDAIAAHFAEISDDSKAQALEGAFQQTQKYVAQAAAR CCCEEEEEEEEECCCCCCHHCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHH LGLKM HCCCC >Mature Secondary Structure AIRFDGRVAIVTGAGNGLGRAHALGLAARGAKVVVNDFGGARDGTGGSMTAAETVVEEI EEEECCEEEEEEECCCCCCHHHHHHHHCCCCEEEEECCCCCCCCCCCCHHHHHHHHHHH RKAGGTAMADGADVSNYEQVKAMVAKATKEWGSVDLMVANAGILRDKSFGKMELSDFQKV HHCCCCEECCCCCCCHHHHHHHHHHHHHHCCCCEEEEEECCCEEECCCCCCCCHHHHHHH IDVHLAGTFYCCKAVWDGMKERNYGRIVLTTSSSGMFGNFGQANYGAAKAGIVGLMNVLA HHHHHHHHHHHHHHHHCCHHHCCCCEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHH QEGRKTDIRVNTVSPTAATRMTEELLPPQALQLMKPEAITPAVLFLLSDNAPTRTTLGAG HCCCCCEEEEEECCCHHHHHHHHHHCCHHHHHHCCCCCCCCEEEEEECCCCCCCEEECCC AGSFAQIKIIETEGINLPEEEWTPDAIAAHFAEISDDSKAQALEGAFQQTQKYVAQAAAR CCCEEEEEEEEECCCCCCHHCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHH LGLKM HCCCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NADPH [C]
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: Oxoacyl-[acyl-carrier-protein]; NADPH; D-3-hydroxy-acyl-ACP; NADP [C]
Specific reaction: Oxoacyl-[acyl-carrier-protein] + NADPH = (3R)-hydroxyacyl-[acyl-carrier-protein] + NADP+ D-3-hydroxy-acyl-ACP + NADP = NADPH + Proton + beta-ketoacyl-ACP [C]
General reaction: Redox reaction [C]
Inhibitor: NA
Structure determination priority: 10.0
TargetDB status: NA
Availability: NA
References: 9634230 [H]