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The map label for this gene is coxS [H]

Identifier: 86750225

GI number: 86750225

Start: 3546825

End: 3547313

Strand: Reverse

Name: coxS [H]

Synonym: RPB_3112

Alternate gene names: 86750225

Gene position: 3547313-3546825 (Counterclockwise)

Preceding gene: 86750226

Following gene: 86750224

Centisome position: 66.53

GC content: 64.62

Gene sequence:

>489_bases
TTGAAAACGCGGGTTGAATTCGAGCTGAACGGCGCGCCGGTCGCCGCCGAAATCGAGCCGAGGCTGACGCTCGGCGACTG
CATCCGCCACGAACTCGGCAAGACCGGGACGCATATCGGCTGCGAGCACGGCGTCTGCGGCGCCTGCACCATCATCATCG
ACGGCGAAGCGGTGCGGTCGTGCTTGACACTCGGCGTGCAGGTCGCTGGCAAATCGGTGATGACGATCGAAGGCCTTGCC
GACGGCGACAATCTCGGACCGTTACAGGCCTCGTTCCAGAAGCACCACGGCCTGCAATGCGGCTTCTGCACGCCGGGCTT
TCTGATGACCGCGCATGCGCTGCTGACGCGCGAGCCCGACGCCGATGAAGAGCGCATCCGCGATGTGCTGTCCGGCAATG
TCTGCCGCTGCACCGGCTATCTGTCGATTGTGAAAGCCGTGATGGAAGCGCGACCGGCCTATCAGCGTGAGCAGGGAGTG
GGGGCGTGA

Upstream 100 bases:

>100_bases
CGTCCGACATCCATGCGTCCGGCGACTATCGCAAATCCCTGGTCGGGACGCTGACTGCGCGTGCGCTGCGCGACGCCGGC
GCGCGTAAAGGAGAGCTTCG

Downstream 100 bases:

>100_bases
ACGAGCGCGTGCCGCTGGTTGGACAGCCGATCGAGCGTGTCGAGGATCCAAAGCTGCTGCGCGGACTCGGCAGCTTCGTC
GACGACGTGCATCGCGACGG

Product: (2Fe-2S)-binding protein

Products: NA

Alternate protein names: CO dehydrogenase subunit S; CO-DH S [H]

Number of amino acids: Translated: 162; Mature: 162

Protein sequence:

>162_residues
MKTRVEFELNGAPVAAEIEPRLTLGDCIRHELGKTGTHIGCEHGVCGACTIIIDGEAVRSCLTLGVQVAGKSVMTIEGLA
DGDNLGPLQASFQKHHGLQCGFCTPGFLMTAHALLTREPDADEERIRDVLSGNVCRCTGYLSIVKAVMEARPAYQREQGV
GA

Sequences:

>Translated_162_residues
MKTRVEFELNGAPVAAEIEPRLTLGDCIRHELGKTGTHIGCEHGVCGACTIIIDGEAVRSCLTLGVQVAGKSVMTIEGLA
DGDNLGPLQASFQKHHGLQCGFCTPGFLMTAHALLTREPDADEERIRDVLSGNVCRCTGYLSIVKAVMEARPAYQREQGV
GA
>Mature_162_residues
MKTRVEFELNGAPVAAEIEPRLTLGDCIRHELGKTGTHIGCEHGVCGACTIIIDGEAVRSCLTLGVQVAGKSVMTIEGLA
DGDNLGPLQASFQKHHGLQCGFCTPGFLMTAHALLTREPDADEERIRDVLSGNVCRCTGYLSIVKAVMEARPAYQREQGV
GA

Specific function: Catalyzes the oxidation of carbon monoxide to carbon dioxide [H]

COG id: COG2080

COG function: function code C; Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS/CutS homologs

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 2Fe-2S ferredoxin-type domain [H]

Homologues:

Organism=Homo sapiens, GI91823271, Length=154, Percent_Identity=35.7142857142857, Blast_Score=82, Evalue=2e-16,
Organism=Homo sapiens, GI71773480, Length=89, Percent_Identity=40.4494382022472, Blast_Score=75, Evalue=2e-14,
Organism=Escherichia coli, GI1786480, Length=159, Percent_Identity=39.622641509434, Blast_Score=125, Evalue=1e-30,
Organism=Escherichia coli, GI1789232, Length=147, Percent_Identity=41.4965986394558, Blast_Score=110, Evalue=3e-26,
Organism=Caenorhabditis elegans, GI32566215, Length=168, Percent_Identity=37.5, Blast_Score=128, Evalue=1e-30,
Organism=Caenorhabditis elegans, GI17539860, Length=156, Percent_Identity=39.1025641025641, Blast_Score=128, Evalue=1e-30,
Organism=Caenorhabditis elegans, GI17540638, Length=155, Percent_Identity=43.8709677419355, Blast_Score=117, Evalue=2e-27,
Organism=Drosophila melanogaster, GI24647199, Length=151, Percent_Identity=37.7483443708609, Blast_Score=101, Evalue=3e-22,
Organism=Drosophila melanogaster, GI24647201, Length=150, Percent_Identity=36.6666666666667, Blast_Score=94, Evalue=3e-20,
Organism=Drosophila melanogaster, GI17737937, Length=170, Percent_Identity=36.4705882352941, Blast_Score=94, Evalue=4e-20,
Organism=Drosophila melanogaster, GI24647197, Length=160, Percent_Identity=35, Blast_Score=90, Evalue=6e-19,
Organism=Drosophila melanogaster, GI24647195, Length=160, Percent_Identity=35, Blast_Score=90, Evalue=6e-19,
Organism=Drosophila melanogaster, GI24647193, Length=152, Percent_Identity=34.8684210526316, Blast_Score=80, Evalue=8e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002888
- InterPro:   IPR012675
- InterPro:   IPR001041 [H]

Pfam domain/function: PF00111 Fer2; PF01799 Fer2_2 [H]

EC number: =1.2.99.2 [H]

Molecular weight: Translated: 17250; Mature: 17250

Theoretical pI: Translated: 5.91; Mature: 5.91

Prosite motif: PS00197 2FE2S_FER_1 ; PS51085 2FE2S_FER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

5.6 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
8.0 %Cys+Met (Translated Protein)
5.6 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
8.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTRVEFELNGAPVAAEIEPRLTLGDCIRHELGKTGTHIGCEHGVCGACTIIIDGEAVRS
CCCEEEEEECCCCEEEECCCCCCHHHHHHHHHCCCCCCCCCCCCCCEEEEEEECCHHHHH
CLTLGVQVAGKSVMTIEGLADGDNLGPLQASFQKHHGLQCGFCTPGFLMTAHALLTREPD
HHHHHHHHCCCEEEEEECCCCCCCCCHHHHHHHHHCCCEECCCCCHHHHHHHHHHHCCCC
ADEERIRDVLSGNVCRCTGYLSIVKAVMEARPAYQREQGVGA
CCHHHHHHHHCCCEEEEHHHHHHHHHHHHHCCHHHHHCCCCC
>Mature Secondary Structure
MKTRVEFELNGAPVAAEIEPRLTLGDCIRHELGKTGTHIGCEHGVCGACTIIIDGEAVRS
CCCEEEEEECCCCEEEECCCCCCHHHHHHHHHCCCCCCCCCCCCCCEEEEEEECCHHHHH
CLTLGVQVAGKSVMTIEGLADGDNLGPLQASFQKHHGLQCGFCTPGFLMTAHALLTREPD
HHHHHHHHCCCEEEEEECCCCCCCCCHHHHHHHHHCCCEECCCCCHHHHHHHHHHHCCCC
ADEERIRDVLSGNVCRCTGYLSIVKAVMEARPAYQREQGVGA
CCHHHHHHHHCCCEEEEHHHHHHHHHHHHHCCHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7721710; 2818128; 10430865; 12475995 [H]