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The map label for this gene is cutM [H]

Identifier: 86750226

GI number: 86750226

Start: 3547310

End: 3548182

Strand: Reverse

Name: cutM [H]

Synonym: RPB_3113

Alternate gene names: 86750226

Gene position: 3548182-3547310 (Counterclockwise)

Preceding gene: 86750227

Following gene: 86750225

Centisome position: 66.55

GC content: 68.27

Gene sequence:

>873_bases
ATGAAGATGCCGCCGTTCGACTATGCGTGCCCGGCGACGCTGGACGAGGCGGTGCGGCTGCTCGCCGCCAACGACGGCGC
CAAGGTGCTGTCCGGCGGCCAGAGCCTGCTGCCGCTGCTGGCGTTCCGGATGGCGTATCCGCCGCTCTTGGTCGACATCC
AGAAGTTGCCTGGCCTTGAAACCATCGACGTGACGGCCAATGGCCTGCGCGTCGGGGCGCGCGTTCGCTGGTGCCAGATC
GAACAGGATGCGCGGCTCGCGACCGCGCATCCGCTGTTCCAGGCGATGATCGATCACGTCGCGCACTACCAGATCCGCAA
CCGCGGCACCGTCGGCGGCAGTCTGGCGCATGCCGATCCCTCCGCCGAGATGCCCGGCGTGGCGCTGGTCTGCGATTGCG
AGATCGTCGCGATCGGACAGGCCGGCACGCGCGTGATCGAGGCCGCCGACTTCTTCGTCGCGGCGCTGGAGACGGCGCTC
GCGTCGGACGAGATCATCACCGAGGTCCGGTTCCCGCGGTGGCAGCCGGGGCGACGCTGGGCGTTTCATGAATTTGCCCG
GCGCAAGGGCGATTTCGCCATGGCCGGCGTTGCGGTGTTCTTCGATCTCGACGGCGACGGCCGGATCGTCGATCCGCATG
TCGGGGTGATCGGCGCCGGCGAAACGCCGCTGCGGCTCACCGCTGTGGAACAGCTACTTGCTGGCTGCAAGCTCGACGAT
GGCCTGATCGCGCGCGCGAAAACGCTGGCGTCGGATTCGGTGGCGCCGTCGTCCGACATCCATGCGTCCGGCGACTATCG
CAAATCCCTGGTCGGGACGCTGACTGCGCGTGCGCTGCGCGACGCCGGCGCGCGTAAAGGAGAGCTTCGTTGA

Upstream 100 bases:

>100_bases
CGCGCACCGAGTTCGACGGCCGCACCACGATCCTCACGGGACCCGGCCACGTGTCCTATCTGCTGCTGCCGCACATCCCG
TCGCAGTCCGGAGCCACGCC

Downstream 100 bases:

>100_bases
AAACGCGGGTTGAATTCGAGCTGAACGGCGCGCCGGTCGCCGCCGAAATCGAGCCGAGGCTGACGCTCGGCGACTGCATC
CGCCACGAACTCGGCAAGAC

Product: molybdopterin dehydrogenase, FAD-binding

Products: NA

Alternate protein names: CO dehydrogenase subunit M; CO-DH M [H]

Number of amino acids: Translated: 290; Mature: 290

Protein sequence:

>290_residues
MKMPPFDYACPATLDEAVRLLAANDGAKVLSGGQSLLPLLAFRMAYPPLLVDIQKLPGLETIDVTANGLRVGARVRWCQI
EQDARLATAHPLFQAMIDHVAHYQIRNRGTVGGSLAHADPSAEMPGVALVCDCEIVAIGQAGTRVIEAADFFVAALETAL
ASDEIITEVRFPRWQPGRRWAFHEFARRKGDFAMAGVAVFFDLDGDGRIVDPHVGVIGAGETPLRLTAVEQLLAGCKLDD
GLIARAKTLASDSVAPSSDIHASGDYRKSLVGTLTARALRDAGARKGELR

Sequences:

>Translated_290_residues
MKMPPFDYACPATLDEAVRLLAANDGAKVLSGGQSLLPLLAFRMAYPPLLVDIQKLPGLETIDVTANGLRVGARVRWCQI
EQDARLATAHPLFQAMIDHVAHYQIRNRGTVGGSLAHADPSAEMPGVALVCDCEIVAIGQAGTRVIEAADFFVAALETAL
ASDEIITEVRFPRWQPGRRWAFHEFARRKGDFAMAGVAVFFDLDGDGRIVDPHVGVIGAGETPLRLTAVEQLLAGCKLDD
GLIARAKTLASDSVAPSSDIHASGDYRKSLVGTLTARALRDAGARKGELR
>Mature_290_residues
MKMPPFDYACPATLDEAVRLLAANDGAKVLSGGQSLLPLLAFRMAYPPLLVDIQKLPGLETIDVTANGLRVGARVRWCQI
EQDARLATAHPLFQAMIDHVAHYQIRNRGTVGGSLAHADPSAEMPGVALVCDCEIVAIGQAGTRVIEAADFFVAALETAL
ASDEIITEVRFPRWQPGRRWAFHEFARRKGDFAMAGVAVFFDLDGDGRIVDPHVGVIGAGETPLRLTAVEQLLAGCKLDD
GLIARAKTLASDSVAPSSDIHASGDYRKSLVGTLTARALRDAGARKGELR

Specific function: Catalyzes the oxidation of carbon monoxide to carbon dioxide [H]

COG id: COG1319

COG function: function code C; Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM/CutM homologs

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FAD-binding PCMH-type domain [H]

Homologues:

Organism=Homo sapiens, GI71773480, Length=226, Percent_Identity=25.6637168141593, Blast_Score=70, Evalue=3e-12,
Organism=Escherichia coli, GI1789231, Length=290, Percent_Identity=30, Blast_Score=92, Evalue=5e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005107
- InterPro:   IPR016169
- InterPro:   IPR016166
- InterPro:   IPR016167
- InterPro:   IPR002346 [H]

Pfam domain/function: PF03450 CO_deh_flav_C; PF00941 FAD_binding_5 [H]

EC number: =1.2.99.2 [H]

Molecular weight: Translated: 31048; Mature: 31048

Theoretical pI: Translated: 6.40; Mature: 6.40

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKMPPFDYACPATLDEAVRLLAANDGAKVLSGGQSLLPLLAFRMAYPPLLVDIQKLPGLE
CCCCCCCCCCCCCHHHHHHHHHCCCCHHHHCCCHHHHHHHHHHHCCCCCEEEHHHCCCCE
TIDVTANGLRVGARVRWCQIEQDARLATAHPLFQAMIDHVAHYQIRNRGTVGGSLAHADP
EEEEECCCEEECCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCC
SAEMPGVALVCDCEIVAIGQAGTRVIEAADFFVAALETALASDEIITEVRFPRWQPGRRW
CCCCCCEEEEECCEEEEECCCCCHHHHHHHHHHHHHHHHHHCHHHHHHHCCCCCCCCCCH
AFHEFARRKGDFAMAGVAVFFDLDGDGRIVDPHVGVIGAGETPLRLTAVEQLLAGCKLDD
HHHHHHHCCCCEEEEEEEEEEEECCCCEEECCCCCEEECCCCCCHHHHHHHHHHCCCCCC
GLIARAKTLASDSVAPSSDIHASGDYRKSLVGTLTARALRDAGARKGELR
CHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure
MKMPPFDYACPATLDEAVRLLAANDGAKVLSGGQSLLPLLAFRMAYPPLLVDIQKLPGLE
CCCCCCCCCCCCCHHHHHHHHHCCCCHHHHCCCHHHHHHHHHHHCCCCCEEEHHHCCCCE
TIDVTANGLRVGARVRWCQIEQDARLATAHPLFQAMIDHVAHYQIRNRGTVGGSLAHADP
EEEEECCCEEECCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCC
SAEMPGVALVCDCEIVAIGQAGTRVIEAADFFVAALETALASDEIITEVRFPRWQPGRRW
CCCCCCEEEEECCEEEEECCCCCHHHHHHHHHHHHHHHHHHCHHHHHHHCCCCCCCCCCH
AFHEFARRKGDFAMAGVAVFFDLDGDGRIVDPHVGVIGAGETPLRLTAVEQLLAGCKLDD
HHHHHHHCCCCEEEEEEEEEEEECCCCEEECCCCCEEECCCCCCHHHHHHHHHHCCCCCC
GLIARAKTLASDSVAPSSDIHASGDYRKSLVGTLTARALRDAGARKGELR
CHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10482497; 2818128; 10966817; 11076018 [H]