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The map label for this gene is mdtA [H]

Identifier: 86750019

GI number: 86750019

Start: 3307639

End: 3309033

Strand: Reverse

Name: mdtA [H]

Synonym: RPB_2902

Alternate gene names: 86750019

Gene position: 3309033-3307639 (Counterclockwise)

Preceding gene: 86750020

Following gene: 86750018

Centisome position: 62.06

GC content: 69.03

Gene sequence:

>1395_bases
ATGCTCTTTAAGCCGGAGACCAACGACGCGTCCGGCACCGGGCCCGGCGCAAACAGTCTGGCGTCGCGCGCCCGGCGGCG
GACGGTGTCGTTGCTGGTGACCGCGATCATCCTCGCCGGGCTCGGCTACATCGCCTGGACCGCGTTCCAGACCAAGCCGG
CGGCCGTCACGGGGCGCGGTGGACCGCGTGGCGACATGGCGGTGCCGGTGCTGGCGGCGACGCCCAAGATTCAGGACGTG
CCGGTGTATCTCGACGGCGTCGGCTCGGTGAAGGCGCTCGCCAATGTCACCGTGCGCGCCCAGGTCGACGGCAAGCTGGT
CGCGGTGAACTTCACCGAAGGTCAGGACGTCAAGGCCGGGGATGTGCTGGCCGAGATCGATCCGGCGATCTATCAGGCGC
AATACGATCAGGCGGTGGCGAAAAAGGCGCAGGACGAGGCGCAGCTCGCCAACGCCAAGATCGATCTCGCCCGCTATCAG
CAACTCGCGGCGTCGAACGCCGGCTCGAAGCAGCAGGCCGACACCCAGAAGGCGACCGTGGCGCAGCTCGACGCGCTGGT
GCGCTCCGATCAGGCGGCGATCGACAACGCCGCGGCGACGCTGAGCTACACCAAGGTGGTGGCGCCGATCTCCGGCCGCG
CCGGCCTGCGCCAGGTCGACAAGGGCAATCTCGTCAAGTCGGCCGACACCACCGGCATCGTGGTGATCACGCAGTTGCAG
CCGATCGCGGTGCAGTTCAGCCTGCCGCAACAGCAGATCGTGCGCGTCAACGCCGCGTCGGCGAAGGGCGCGCTGGCGGT
CGACGTGTTCGGCAATGACGGCGTCACCGTCATCGATACCGGCGTGCTCAGGGGCATCGACAATCAGGTCGATCAAACCA
CCGGCACGGTGAAGCTGAAGGCGGAATTTCCGAACACCAGATTCCAGCTCTGGCCCGGGCAATTCGTCAATGTCCGACTC
AAGGTCGAGACGCTGAACCAGGTCGTGGTGGTGCCGACCTCGGCGGTGCAGCGCGGACCGGCCGGGACATTCAGCTACGT
CATCGACCAGGACAATGTGGTGCATGCGCAGCCCGTCAAGGTGACGCAGCAGAACGAAACCGAGGCGGTAATCGCCAGCG
GGCTGACGCCCGCGGATCGTGTCGTCACCACCGGATTCGCCAATCTGTCCGAGGGTGCCAAGGTCAGGATCGGCGACGGC
GGCCAGGCGCCGGCCGTCGATCTGGCGCCGCGCAAGCGCCGCGGCCCGCCCGGCGATCAGGCCAAGCCGGGCGAAGGTGG
CGCCGCCGAACAGGGCAAGCGCCGCCGCGGCGAGGGCGGCGCAGGGGCGCCGGGACAGACCGGGCAGGCGCCCGCGGCGG
GCGCCGAACCGGCGGGGGCTGCGAAGGCGCAGTGA

Upstream 100 bases:

>100_bases
GATGCGCTGATCCAGACGCAATTGGCGCGCTATCTGGCGATCGTCAGCCTGTTTCAGGCGCTCGGGGGCGGCTGGGAGCC
GAGGATGGAAAGACCGCTCA

Downstream 100 bases:

>100_bases
GCCTTCGCCGCCGCCGATGTGACGACATGAAGCCGCAGCGCTGAGGACAGAAGCATGAGCGTCTCCGAGCCGTTCATCCG
GCGCCCGATCGCAACCTCGC

Product: secretion protein HlyD

Products: NA

Alternate protein names: Multidrug transporter mdtA [H]

Number of amino acids: Translated: 464; Mature: 464

Protein sequence:

>464_residues
MLFKPETNDASGTGPGANSLASRARRRTVSLLVTAIILAGLGYIAWTAFQTKPAAVTGRGGPRGDMAVPVLAATPKIQDV
PVYLDGVGSVKALANVTVRAQVDGKLVAVNFTEGQDVKAGDVLAEIDPAIYQAQYDQAVAKKAQDEAQLANAKIDLARYQ
QLAASNAGSKQQADTQKATVAQLDALVRSDQAAIDNAAATLSYTKVVAPISGRAGLRQVDKGNLVKSADTTGIVVITQLQ
PIAVQFSLPQQQIVRVNAASAKGALAVDVFGNDGVTVIDTGVLRGIDNQVDQTTGTVKLKAEFPNTRFQLWPGQFVNVRL
KVETLNQVVVVPTSAVQRGPAGTFSYVIDQDNVVHAQPVKVTQQNETEAVIASGLTPADRVVTTGFANLSEGAKVRIGDG
GQAPAVDLAPRKRRGPPGDQAKPGEGGAAEQGKRRRGEGGAGAPGQTGQAPAAGAEPAGAAKAQ

Sequences:

>Translated_464_residues
MLFKPETNDASGTGPGANSLASRARRRTVSLLVTAIILAGLGYIAWTAFQTKPAAVTGRGGPRGDMAVPVLAATPKIQDV
PVYLDGVGSVKALANVTVRAQVDGKLVAVNFTEGQDVKAGDVLAEIDPAIYQAQYDQAVAKKAQDEAQLANAKIDLARYQ
QLAASNAGSKQQADTQKATVAQLDALVRSDQAAIDNAAATLSYTKVVAPISGRAGLRQVDKGNLVKSADTTGIVVITQLQ
PIAVQFSLPQQQIVRVNAASAKGALAVDVFGNDGVTVIDTGVLRGIDNQVDQTTGTVKLKAEFPNTRFQLWPGQFVNVRL
KVETLNQVVVVPTSAVQRGPAGTFSYVIDQDNVVHAQPVKVTQQNETEAVIASGLTPADRVVTTGFANLSEGAKVRIGDG
GQAPAVDLAPRKRRGPPGDQAKPGEGGAAEQGKRRRGEGGAGAPGQTGQAPAAGAEPAGAAKAQ
>Mature_464_residues
MLFKPETNDASGTGPGANSLASRARRRTVSLLVTAIILAGLGYIAWTAFQTKPAAVTGRGGPRGDMAVPVLAATPKIQDV
PVYLDGVGSVKALANVTVRAQVDGKLVAVNFTEGQDVKAGDVLAEIDPAIYQAQYDQAVAKKAQDEAQLANAKIDLARYQ
QLAASNAGSKQQADTQKATVAQLDALVRSDQAAIDNAAATLSYTKVVAPISGRAGLRQVDKGNLVKSADTTGIVVITQLQ
PIAVQFSLPQQQIVRVNAASAKGALAVDVFGNDGVTVIDTGVLRGIDNQVDQTTGTVKLKAEFPNTRFQLWPGQFVNVRL
KVETLNQVVVVPTSAVQRGPAGTFSYVIDQDNVVHAQPVKVTQQNETEAVIASGLTPADRVVTTGFANLSEGAKVRIGDG
GQAPAVDLAPRKRRGPPGDQAKPGEGGAAEQGKRRRGEGGAGAPGQTGQAPAAGAEPAGAAKAQ

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family [H]

Homologues:

Organism=Escherichia coli, GI87082036, Length=349, Percent_Identity=45.5587392550143, Blast_Score=288, Evalue=4e-79,
Organism=Escherichia coli, GI1786668, Length=371, Percent_Identity=34.7708894878706, Blast_Score=163, Evalue=3e-41,
Organism=Escherichia coli, GI1789665, Length=317, Percent_Identity=35.3312302839117, Blast_Score=156, Evalue=3e-39,
Organism=Escherichia coli, GI1789929, Length=307, Percent_Identity=31.2703583061889, Blast_Score=140, Evalue=1e-34,
Organism=Escherichia coli, GI87081796, Length=314, Percent_Identity=25.1592356687898, Blast_Score=71, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022824
- InterPro:   IPR006143 [H]

Pfam domain/function: PF00529 HlyD [H]

EC number: NA

Molecular weight: Translated: 47895; Mature: 47895

Theoretical pI: Translated: 9.96; Mature: 9.96

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.4 %Met     (Translated Protein)
0.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.4 %Met     (Mature Protein)
0.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLFKPETNDASGTGPGANSLASRARRRTVSLLVTAIILAGLGYIAWTAFQTKPAAVTGRG
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCCEEECCC
GPRGDMAVPVLAATPKIQDVPVYLDGVGSVKALANVTVRAQVDGKLVAVNFTEGQDVKAG
CCCCCCEEEEEECCCCCCCCCEEEECCCCCEEHHEEEEEEEECCEEEEEEECCCCCCCCC
DVLAEIDPAIYQAQYDQAVAKKAQDEAQLANAKIDLARYQQLAASNAGSKQQADTQKATV
CCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCEEHHHHHHHHHHCCCCCCHHHHHHHHHH
AQLDALVRSDQAAIDNAAATLSYTKVVAPISGRAGLRQVDKGNLVKSADTTGIVVITQLQ
HHHHHHHHCCHHHHHHHHHEEEEEEEEECCCCCCCCCCCCCCCEEECCCCCCEEEEEECC
PIAVQFSLPQQQIVRVNAASAKGALAVDVFGNDGVTVIDTGVLRGIDNQVDQTTGTVKLK
EEEEEEECCHHHEEEEECCCCCCEEEEEEECCCCEEEEECHHHHCCCCHHHCCCCEEEEE
AEFPNTRFQLWPGQFVNVRLKVETLNQVVVVPTSAVQRGPAGTFSYVIDQDNVVHAQPVK
EECCCCEEEECCCCEEEEEEEEEECCEEEEEECHHHCCCCCCCEEEEECCCCEEECCCEE
VTQQNETEAVIASGLTPADRVVTTGFANLSEGAKVRIGDGGQAPAVDLAPRKRRGPPGDQ
EECCCCCCEEEECCCCCHHHEEECCCCCCCCCCEEEECCCCCCCEECCCCCCCCCCCCCC
AKPGEGGAAEQGKRRRGEGGAGAPGQTGQAPAAGAEPAGAAKAQ
CCCCCCCCCHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MLFKPETNDASGTGPGANSLASRARRRTVSLLVTAIILAGLGYIAWTAFQTKPAAVTGRG
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCCEEECCC
GPRGDMAVPVLAATPKIQDVPVYLDGVGSVKALANVTVRAQVDGKLVAVNFTEGQDVKAG
CCCCCCEEEEEECCCCCCCCCEEEECCCCCEEHHEEEEEEEECCEEEEEEECCCCCCCCC
DVLAEIDPAIYQAQYDQAVAKKAQDEAQLANAKIDLARYQQLAASNAGSKQQADTQKATV
CCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCEEHHHHHHHHHHCCCCCCHHHHHHHHHH
AQLDALVRSDQAAIDNAAATLSYTKVVAPISGRAGLRQVDKGNLVKSADTTGIVVITQLQ
HHHHHHHHCCHHHHHHHHHEEEEEEEEECCCCCCCCCCCCCCCEEECCCCCCEEEEEECC
PIAVQFSLPQQQIVRVNAASAKGALAVDVFGNDGVTVIDTGVLRGIDNQVDQTTGTVKLK
EEEEEEECCHHHEEEEECCCCCCEEEEEEECCCCEEEEECHHHHCCCCHHHCCCCEEEEE
AEFPNTRFQLWPGQFVNVRLKVETLNQVVVVPTSAVQRGPAGTFSYVIDQDNVVHAQPVK
EECCCCEEEECCCCEEEEEEEEEECCEEEEEECHHHCCCCCCCEEEEECCCCEEECCCEE
VTQQNETEAVIASGLTPADRVVTTGFANLSEGAKVRIGDGGQAPAVDLAPRKRRGPPGDQ
EECCCCCCEEEECCCCCHHHEEECCCCCCCCCCEEEECCCCCCCEECCCCCCCCCCCCCC
AKPGEGGAAEQGKRRRGEGGAGAPGQTGQAPAAGAEPAGAAKAQ
CCCCCCCCCHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA