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The map label for this gene is hfq [H]

Identifier: 86749995

GI number: 86749995

Start: 3276456

End: 3276704

Strand: Reverse

Name: hfq [H]

Synonym: RPB_2878

Alternate gene names: 86749995

Gene position: 3276704-3276456 (Counterclockwise)

Preceding gene: 86749996

Following gene: 86749994

Centisome position: 61.46

GC content: 52.21

Gene sequence:

>249_bases
ATGGCGGCAGACCGCGCACAAAATCTACAAGACACCTTCCTGAACCACGTTCGAAAGACCAAGACTCCTTTGACGATTTT
CCTGGTGAACGGGGTCAAATTGCAAGGCATTGTCACTTGGTTCGATAATTTTTGCCTGTTGCTGCGGCGCGATGGTCATT
CGCAGCTGGTCTACAAGCATGCGATTTCGACGATTATGCCAGGCGCGCCGATCCAGTTGTTCGAAGGCGGCGAGGATTCT
CCAGCTTGA

Upstream 100 bases:

>100_bases
GCCTCCGGAGGGGGATCTCAGGGGGGCCGACAACCGAGGTGAAGCTCCGCAGAGAGACGCGCCGCGGCAAAAAAAGACAA
TTCCAATTGCGGGAATAAAA

Downstream 100 bases:

>100_bases
GAAGGTCCTGATTGGAACCCCGCAGCTTTGACGGGGGCGCCGACCGGCCGCGGTCGGCGACAGACGGCCAGACCGGGCGG
GTAATCGTCGTCGGGCCGTA

Product: RNA-binding protein Hfq

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 82; Mature: 81

Protein sequence:

>82_residues
MAADRAQNLQDTFLNHVRKTKTPLTIFLVNGVKLQGIVTWFDNFCLLLRRDGHSQLVYKHAISTIMPGAPIQLFEGGEDS
PA

Sequences:

>Translated_82_residues
MAADRAQNLQDTFLNHVRKTKTPLTIFLVNGVKLQGIVTWFDNFCLLLRRDGHSQLVYKHAISTIMPGAPIQLFEGGEDS
PA
>Mature_81_residues
AADRAQNLQDTFLNHVRKTKTPLTIFLVNGVKLQGIVTWFDNFCLLLRRDGHSQLVYKHAISTIMPGAPIQLFEGGEDSP
A

Specific function: RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs [H]

COG id: COG1923

COG function: function code R; Uncharacterized host factor I protein

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hfq family [H]

Homologues:

Organism=Escherichia coli, GI1790614, Length=67, Percent_Identity=52.2388059701493, Blast_Score=81, Evalue=2e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005001
- InterPro:   IPR010920
- InterPro:   IPR001163 [H]

Pfam domain/function: PF01423 LSM [H]

EC number: NA

Molecular weight: Translated: 9167; Mature: 9036

Theoretical pI: Translated: 8.53; Mature: 8.53

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAADRAQNLQDTFLNHVRKTKTPLTIFLVNGVKLQGIVTWFDNFCLLLRRDGHSQLVYKH
CCCCCCCCHHHHHHHHHHHCCCCEEEEEECCEEEEHHHHHHHHHEEEEECCCCCHHHHHH
AISTIMPGAPIQLFEGGEDSPA
HHHHHCCCCCEEEEECCCCCCC
>Mature Secondary Structure 
AADRAQNLQDTFLNHVRKTKTPLTIFLVNGVKLQGIVTWFDNFCLLLRRDGHSQLVYKH
CCCCCCCHHHHHHHHHHHCCCCEEEEEECCEEEEHHHHHHHHHEEEEECCCCCHHHHHH
AISTIMPGAPIQLFEGGEDSPA
HHHHHCCCCCEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12597275 [H]