Click here to switch to the map view.

The map label for this gene is hflX [H]

Identifier: 86749994

GI number: 86749994

Start: 3275071

End: 3276444

Strand: Reverse

Name: hflX [H]

Synonym: RPB_2877

Alternate gene names: 86749994

Gene position: 3276444-3275071 (Counterclockwise)

Preceding gene: 86749995

Following gene: 86749993

Centisome position: 61.45

GC content: 68.49

Gene sequence:

>1374_bases
TTGGAACCCCGCAGCTTTGACGGGGGCGCCGACCGGCCGCGGTCGGCGACAGACGGCCAGACCGGGCGGGTAATCGTCGT
CGGGCCGTATCTTCGTGTCCGCAAGACCGATCCCGATGCCGGCGGAATGAATGCCGTGCGCGACAGCGACGCCCGCCTCG
ACGAGGCGGCGGGGCTTGCGCGCGCCATCGATCTGGAGATCGCCGAGGCGGTGCTGACGCCGATCAGTCAGATCCGCCCG
GCGACCTATCTCGGCAAGGGCAAGGTCGAAGAGATCCTCGGCATCATCAAAGGCCACGAGGCCGATCTCGTGGTGATGGA
TTGCGCGCTGTCGCCGATCCAGCAGCGCAATCTGGAGAAGGCGTGGAGCGCCAAGGTGCTCGATCGTACCGGGCTGATCC
TGGAGATCTTCGGCCGCCGCGCCAAGACCAAGGAAGGCGCGCTGCAGGTCGAACTCGCGCATCTGAACTATCAACGCTCG
CGGCTGGTGCGATCCTGGACCCATCTCGAACGCCAGCGCGGCGGCTTCGGCTTCATGGGCGGCCCCGGCGAAACCCAGAT
CGAGGCCGACCGGCGGCTGATCGGCGATCGAATCTCGCGGCTCGAAAACGAACTGAAGAAGGTGCAGGCGACGCGGCGGC
TGCACCGCGCCGGCCGCCAGCGCGTGCCGTATCGCGTCGTCGCACTGGTCGGCTACACCAATGCCGGCAAGTCGACGCTG
TTCAACCGGCTGACCCGCGCCGACGTGCAGGCCGCCGACATGCTGTTCGCGACGCTGGACCCGACGCTGCGCGCCTTGAC
CTTGCCGCACGGCGGCAAGGCGATGCTGTCCGACACCGTGGGTTTCATTTCCAACCTCCCGACCCAACTCGTTGCGGCGT
TCCGCGCCACGCTGGAGGAGGTGCTGGAAGCCGATCTGATCCTGCACGTCCGCGACATCTCGCACGAAGATGCCGAGGCC
CAGGAGCGCGACGTCGACGCGGTGCTGCGCCAGCTCGGCGTCGAGGCCGACGGCGGGCGCATCCTCGAAATCTGGAACAA
GATCGACCGCTTCGAGCCGGAGCAGCGCGAAGAGCTGCGCAACATCGCGGCGCGGCGGTCCGAGGATCGCCCGTGCTTCA
TGGTGTCGGCGGTGAGCGGCGAGGGCGTCGACGAGCTGTTGCTGGCGATCGAGCAGCGGCTGGCGGCCTGGCGTTCGGTG
CTCGACCTGACCATCGACGCCGCCGACGGGGCCGGCGTGAGCTGGCTGCATCGCAACGCCGAGGTGCTGTCCAAGGAGCT
GCGCGACGGCCGCTACGCCATGACGGTGCGGGTCGACGAGACCAAGCGCGACGTCGTCGTCGAGCGCTTCGGCGCGGTGC
TGCGCGAGGACTGA

Upstream 100 bases:

>100_bases
CGCAGCTGGTCTACAAGCATGCGATTTCGACGATTATGCCAGGCGCGCCGATCCAGTTGTTCGAAGGCGGCGAGGATTCT
CCAGCTTGAGAAGGTCCTGA

Downstream 100 bases:

>100_bases
TCGGGGCGCGCCGCCGACGTTTCGGGGCGATCCGGGAAGGCGCTTCGGGCGCCCAGCCAAACTCCGGCTAAGTCATTGGA
AAATCGGCTGGAAAAAGCCG

Product: GTP-binding protein, HSR1-related

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 457; Mature: 457

Protein sequence:

>457_residues
MEPRSFDGGADRPRSATDGQTGRVIVVGPYLRVRKTDPDAGGMNAVRDSDARLDEAAGLARAIDLEIAEAVLTPISQIRP
ATYLGKGKVEEILGIIKGHEADLVVMDCALSPIQQRNLEKAWSAKVLDRTGLILEIFGRRAKTKEGALQVELAHLNYQRS
RLVRSWTHLERQRGGFGFMGGPGETQIEADRRLIGDRISRLENELKKVQATRRLHRAGRQRVPYRVVALVGYTNAGKSTL
FNRLTRADVQAADMLFATLDPTLRALTLPHGGKAMLSDTVGFISNLPTQLVAAFRATLEEVLEADLILHVRDISHEDAEA
QERDVDAVLRQLGVEADGGRILEIWNKIDRFEPEQREELRNIAARRSEDRPCFMVSAVSGEGVDELLLAIEQRLAAWRSV
LDLTIDAADGAGVSWLHRNAEVLSKELRDGRYAMTVRVDETKRDVVVERFGAVLRED

Sequences:

>Translated_457_residues
MEPRSFDGGADRPRSATDGQTGRVIVVGPYLRVRKTDPDAGGMNAVRDSDARLDEAAGLARAIDLEIAEAVLTPISQIRP
ATYLGKGKVEEILGIIKGHEADLVVMDCALSPIQQRNLEKAWSAKVLDRTGLILEIFGRRAKTKEGALQVELAHLNYQRS
RLVRSWTHLERQRGGFGFMGGPGETQIEADRRLIGDRISRLENELKKVQATRRLHRAGRQRVPYRVVALVGYTNAGKSTL
FNRLTRADVQAADMLFATLDPTLRALTLPHGGKAMLSDTVGFISNLPTQLVAAFRATLEEVLEADLILHVRDISHEDAEA
QERDVDAVLRQLGVEADGGRILEIWNKIDRFEPEQREELRNIAARRSEDRPCFMVSAVSGEGVDELLLAIEQRLAAWRSV
LDLTIDAADGAGVSWLHRNAEVLSKELRDGRYAMTVRVDETKRDVVVERFGAVLRED
>Mature_457_residues
MEPRSFDGGADRPRSATDGQTGRVIVVGPYLRVRKTDPDAGGMNAVRDSDARLDEAAGLARAIDLEIAEAVLTPISQIRP
ATYLGKGKVEEILGIIKGHEADLVVMDCALSPIQQRNLEKAWSAKVLDRTGLILEIFGRRAKTKEGALQVELAHLNYQRS
RLVRSWTHLERQRGGFGFMGGPGETQIEADRRLIGDRISRLENELKKVQATRRLHRAGRQRVPYRVVALVGYTNAGKSTL
FNRLTRADVQAADMLFATLDPTLRALTLPHGGKAMLSDTVGFISNLPTQLVAAFRATLEEVLEADLILHVRDISHEDAEA
QERDVDAVLRQLGVEADGGRILEIWNKIDRFEPEQREELRNIAARRSEDRPCFMVSAVSGEGVDELLLAIEQRLAAWRSV
LDLTIDAADGAGVSWLHRNAEVLSKELRDGRYAMTVRVDETKRDVVVERFGAVLRED

Specific function: Unknown

COG id: COG2262

COG function: function code R; GTPases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 G (guanine nucleotide-binding) domain [H]

Homologues:

Organism=Homo sapiens, GI310133118, Length=267, Percent_Identity=37.8277153558052, Blast_Score=144, Evalue=1e-34,
Organism=Homo sapiens, GI310133116, Length=265, Percent_Identity=37.7358490566038, Blast_Score=142, Evalue=7e-34,
Organism=Homo sapiens, GI310124269, Length=246, Percent_Identity=38.2113821138211, Blast_Score=140, Evalue=2e-33,
Organism=Homo sapiens, GI310124267, Length=246, Percent_Identity=38.2113821138211, Blast_Score=140, Evalue=2e-33,
Organism=Homo sapiens, GI310124171, Length=246, Percent_Identity=38.2113821138211, Blast_Score=140, Evalue=2e-33,
Organism=Homo sapiens, GI310124169, Length=246, Percent_Identity=38.2113821138211, Blast_Score=140, Evalue=2e-33,
Organism=Escherichia coli, GI1790615, Length=347, Percent_Identity=45.2449567723343, Blast_Score=265, Evalue=3e-72,
Organism=Caenorhabditis elegans, GI17561038, Length=421, Percent_Identity=30.8788598574822, Blast_Score=167, Evalue=1e-41,
Organism=Drosophila melanogaster, GI24650079, Length=447, Percent_Identity=32.4384787472036, Blast_Score=165, Evalue=5e-41,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009022
- InterPro:   IPR016496
- InterPro:   IPR006073
- InterPro:   IPR002917 [H]

Pfam domain/function: PF01926 MMR_HSR1 [H]

EC number: NA

Molecular weight: Translated: 50772; Mature: 50772

Theoretical pI: Translated: 6.54; Mature: 6.54

Prosite motif: PS00216 SUGAR_TRANSPORT_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEPRSFDGGADRPRSATDGQTGRVIVVGPYLRVRKTDPDAGGMNAVRDSDARLDEAAGLA
CCCCCCCCCCCCCCCCCCCCCCEEEEECCCEEEEECCCCCCCCCCCCCCCHHHHHHHHHH
RAIDLEIAEAVLTPISQIRPATYLGKGKVEEILGIIKGHEADLVVMDCALSPIQQRNLEK
HHHHHHHHHHHHHHHHHHCCCHHCCCCCHHHHHHHHCCCCCCEEEEECCCCHHHHHHHHH
AWSAKVLDRTGLILEIFGRRAKTKEGALQVELAHLNYQRSRLVRSWTHLERQRGGFGFMG
HHHHHHHHHCCHHHHHHCCCCCCCCCCEEEEEEHHCHHHHHHHHHHHHHHHHCCCCCCCC
GPGETQIEADRRLIGDRISRLENELKKVQATRRLHRAGRQRVPYRVVALVGYTNAGKSTL
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCCHHHH
FNRLTRADVQAADMLFATLDPTLRALTLPHGGKAMLSDTVGFISNLPTQLVAAFRATLEE
HHHHHHHHHHHHHHHHHHCCCHHHEEECCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHH
VLEADLILHVRDISHEDAEAQERDVDAVLRQLGVEADGGRILEIWNKIDRFEPEQREELR
HHHHHHEEEEECCCCCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCHHHHHHH
NIAARRSEDRPCFMVSAVSGEGVDELLLAIEQRLAAWRSVLDLTIDAADGAGVSWLHRNA
HHHHHCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHEEECCCCCCHHHHHHHH
EVLSKELRDGRYAMTVRVDETKRDVVVERFGAVLRED
HHHHHHHCCCCEEEEEEECCCHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MEPRSFDGGADRPRSATDGQTGRVIVVGPYLRVRKTDPDAGGMNAVRDSDARLDEAAGLA
CCCCCCCCCCCCCCCCCCCCCCEEEEECCCEEEEECCCCCCCCCCCCCCCHHHHHHHHHH
RAIDLEIAEAVLTPISQIRPATYLGKGKVEEILGIIKGHEADLVVMDCALSPIQQRNLEK
HHHHHHHHHHHHHHHHHHCCCHHCCCCCHHHHHHHHCCCCCCEEEEECCCCHHHHHHHHH
AWSAKVLDRTGLILEIFGRRAKTKEGALQVELAHLNYQRSRLVRSWTHLERQRGGFGFMG
HHHHHHHHHCCHHHHHHCCCCCCCCCCEEEEEEHHCHHHHHHHHHHHHHHHHCCCCCCCC
GPGETQIEADRRLIGDRISRLENELKKVQATRRLHRAGRQRVPYRVVALVGYTNAGKSTL
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCCHHHH
FNRLTRADVQAADMLFATLDPTLRALTLPHGGKAMLSDTVGFISNLPTQLVAAFRATLEE
HHHHHHHHHHHHHHHHHHCCCHHHEEECCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHH
VLEADLILHVRDISHEDAEAQERDVDAVLRQLGVEADGGRILEIWNKIDRFEPEQREELR
HHHHHHEEEEECCCCCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCHHHHHHH
NIAARRSEDRPCFMVSAVSGEGVDELLLAIEQRLAAWRSVLDLTIDAADGAGVSWLHRNA
HHHHHCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHEEECCCCCCHHHHHHHH
EVLSKELRDGRYAMTVRVDETKRDVVVERFGAVLRED
HHHHHHHCCCCEEEEEEECCCHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8248183; 7610040; 9278503; 2020545; 3040675 [H]