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The map label for this gene is cdsA [H]

Identifier: 86749940

GI number: 86749940

Start: 3217952

End: 3218800

Strand: Reverse

Name: cdsA [H]

Synonym: RPB_2823

Alternate gene names: 86749940

Gene position: 3218800-3217952 (Counterclockwise)

Preceding gene: 86749941

Following gene: 86749939

Centisome position: 60.37

GC content: 66.31

Gene sequence:

>849_bases
GTGAGCCAGGACAACGCGGCGCCAGCGCCGGCAGCCGAGCAGGGCTCCCGCAATTTCTGGCAGCGTGTCGGCGCCGCCCT
CGTGCTTGCGCCGGGCGCGATTGCGGTTGCATATTTCGGCGGCTGGGCGTGGGCCGTGCTGGTGACCGCCGTCGCCATCG
GCCTTTTCCTGGAGTGGCTCACGATCGTCGGAGCTGCGCGCGATTTCCGCGTGCTGGTGATCGGCTGCCTGACATTGCTG
GTCTGTGGCCTCGGGCTGATATTCGACAAGCCGGGGCCGGCGGTGCTGGCGGCCACGCTCGGCGTCGGCGGGCTGGCGGC
GCTGGGCGATCAACCGCGGCGCTGGACCACCTCCGGGCTCGGCTATGCCGCCCTGGCGCTGATCGCCTCGATCCTGCTGC
GGCGCGATCCCGACTACGGCTTCTCTGCGCTGGTCCTGATTTTTCTGATCGTCTGGGGTAGTGACATCGGCGGCTATTTC
GCCGGCCGCAGCATCGGCGGCCCGAAATTATGGCCGCGGGTCAGCCCGAAGAAGACTTGGGCGGGGGCGATTGGCGGCCT
TGTCCTCAGCCTGCTGGTCGGGCTCGTTTTCGCACTGTCGGGATTTGGAAAAATCATTCCGCTGCTGATCCTTGCGGCGG
TTCTTTCAACTAGTTCCCAACTCGGCGATTTGTTCGAATCCGCGGTGAAGCGCCGGTTCGGCGTCAAGGATTCGAGCCAC
ATCATTCCCGGCCATGGCGGGCTGCTCGACCGGCTCGACGGATATGTCGCGGCCGTGGCGGTGGCCGTGCTGATCGGGCT
GATGCGAGGATCGCCGGATGGTATTGGCCGCGGTCTTATGGTGTGGTGA

Upstream 100 bases:

>100_bases
CGGACTTCGACAAGGCCGCGCTGGAAGGCGCGATCGCCGAATATGCCCGACGCGAGCGCCGTTTCGGCGGCTTGGCCGCG
AAAACAGGATCGTGACGCGC

Downstream 100 bases:

>100_bases
TCCGATGAGTGCAGTCCCTTTGAAAAATACCGACGCCGCCCATGATGGTGTGCGCAGCATCAGCGTCCTCGGCGCCACCG
GGTCGATCGGCGACAGCACG

Product: phosphatidate cytidylyltransferase

Products: NA

Alternate protein names: CDP-DAG synthase; CDP-DG synthase; CDP-diacylglycerol synthase; CDS; CDP-diglyceride pyrophosphorylase; CDP-diglyceride synthase; CTP:phosphatidate cytidylyltransferase [H]

Number of amino acids: Translated: 282; Mature: 281

Protein sequence:

>282_residues
MSQDNAAPAPAAEQGSRNFWQRVGAALVLAPGAIAVAYFGGWAWAVLVTAVAIGLFLEWLTIVGAARDFRVLVIGCLTLL
VCGLGLIFDKPGPAVLAATLGVGGLAALGDQPRRWTTSGLGYAALALIASILLRRDPDYGFSALVLIFLIVWGSDIGGYF
AGRSIGGPKLWPRVSPKKTWAGAIGGLVLSLLVGLVFALSGFGKIIPLLILAAVLSTSSQLGDLFESAVKRRFGVKDSSH
IIPGHGGLLDRLDGYVAAVAVAVLIGLMRGSPDGIGRGLMVW

Sequences:

>Translated_282_residues
MSQDNAAPAPAAEQGSRNFWQRVGAALVLAPGAIAVAYFGGWAWAVLVTAVAIGLFLEWLTIVGAARDFRVLVIGCLTLL
VCGLGLIFDKPGPAVLAATLGVGGLAALGDQPRRWTTSGLGYAALALIASILLRRDPDYGFSALVLIFLIVWGSDIGGYF
AGRSIGGPKLWPRVSPKKTWAGAIGGLVLSLLVGLVFALSGFGKIIPLLILAAVLSTSSQLGDLFESAVKRRFGVKDSSH
IIPGHGGLLDRLDGYVAAVAVAVLIGLMRGSPDGIGRGLMVW
>Mature_281_residues
SQDNAAPAPAAEQGSRNFWQRVGAALVLAPGAIAVAYFGGWAWAVLVTAVAIGLFLEWLTIVGAARDFRVLVIGCLTLLV
CGLGLIFDKPGPAVLAATLGVGGLAALGDQPRRWTTSGLGYAALALIASILLRRDPDYGFSALVLIFLIVWGSDIGGYFA
GRSIGGPKLWPRVSPKKTWAGAIGGLVLSLLVGLVFALSGFGKIIPLLILAAVLSTSSQLGDLFESAVKRRFGVKDSSHI
IPGHGGLLDRLDGYVAAVAVAVLIGLMRGSPDGIGRGLMVW

Specific function: Phospholipid biosynthesis. [C]

COG id: COG0575

COG function: function code I; CDP-diglyceride synthetase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CDS family [H]

Homologues:

Organism=Escherichia coli, GI87081696, Length=120, Percent_Identity=46.6666666666667, Blast_Score=102, Evalue=4e-23,
Organism=Escherichia coli, GI1787677, Length=113, Percent_Identity=39.8230088495575, Blast_Score=74, Evalue=9e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000374 [H]

Pfam domain/function: PF01148 CTP_transf_1 [H]

EC number: =2.7.7.41 [H]

Molecular weight: Translated: 29213; Mature: 29082

Theoretical pI: Translated: 10.16; Mature: 10.16

Prosite motif: PS01315 CDS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSQDNAAPAPAAEQGSRNFWQRVGAALVLAPGAIAVAYFGGWAWAVLVTAVAIGLFLEWL
CCCCCCCCCCCHHHCHHHHHHHHCHHHEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TIVGAARDFRVLVIGCLTLLVCGLGLIFDKPGPAVLAATLGVGGLAALGDQPRRWTTSGL
HHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCCHHHHHCCCCCCCCCCCC
GYAALALIASILLRRDPDYGFSALVLIFLIVWGSDIGGYFAGRSIGGPKLWPRVSPKKTW
HHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCHHHCCCCCCCCCCCCCCCCCHHH
AGAIGGLVLSLLVGLVFALSGFGKIIPLLILAAVLSTSSQLGDLFESAVKRRFGVKDSSH
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHCCCCCCC
IIPGHGGLLDRLDGYVAAVAVAVLIGLMRGSPDGIGRGLMVW
CCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCC
>Mature Secondary Structure 
SQDNAAPAPAAEQGSRNFWQRVGAALVLAPGAIAVAYFGGWAWAVLVTAVAIGLFLEWL
CCCCCCCCCCHHHCHHHHHHHHCHHHEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TIVGAARDFRVLVIGCLTLLVCGLGLIFDKPGPAVLAATLGVGGLAALGDQPRRWTTSGL
HHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCCHHHHHCCCCCCCCCCCC
GYAALALIASILLRRDPDYGFSALVLIFLIVWGSDIGGYFAGRSIGGPKLWPRVSPKKTW
HHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCHHHCCCCCCCCCCCCCCCCCHHH
AGAIGGLVLSLLVGLVFALSGFGKIIPLLILAAVLSTSSQLGDLFESAVKRRFGVKDSSH
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHCCCCCCC
IIPGHGGLLDRLDGYVAAVAVAVLIGLMRGSPDGIGRGLMVW
CCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA