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The map label for this gene is siaT [H]

Identifier: 86749802

GI number: 86749802

Start: 3068033

End: 3069916

Strand: Reverse

Name: siaT [H]

Synonym: RPB_2685

Alternate gene names: 86749802

Gene position: 3069916-3068033 (Counterclockwise)

Preceding gene: 86749803

Following gene: 86749801

Centisome position: 57.58

GC content: 67.46

Gene sequence:

>1884_bases
ATGACCCACGCCGAGATCCCGCAACTGGCGGCTGGAAAGCCGCTCGACATTGCGACGCGCAGGTCGCTGATCGGCGCGTT
GGACTCCGGGCTGGGTCTGCTGGTCGAGATCCCCGCGGCGCTTTTGGTGGTCGCGGAGATCGTCGTGCTGTTCGCCGGCG
TGGTGTCGCGCTACGTGTTTCACAGCCCGCTGATCTGGTCGGACGAGCTCGCCTCGATCCTGTTCCTGTGGCTGGCGATG
TTCGGCGCCGCGGTGGCGTTCCGCCGTGGCGAGCACATGCGGATGACCGCGCTGGTGGCGAGCGCATCGCCCCGGCTGCG
CGCGTTTCTCGATCTGGTCGCGATCTGCGCGGCGCTGGCCTTCCTGCTGCTGATCGCGGCGCCGGCTTACGACTACGCCT
ACGAGGAAAGCTACATCACCACGCCGGCGCTGTCGCTGTCGAACGCCTGGCGCGCCGCGGCGCTACCGGTCGGCATCGTG
CTGATGACGCTGTTCGCGTTGCTGCGGCTGATCCGGTTCGGCGACTGGCGGCTGGTGGCGGGCGCCGCCCTCACCGTCGC
CGTGCTGATCGGCGCGTTCTGGCTGGCGCAGCCGCTGTTCAAGCCGCTCGGCAATCTCAATCTGGTGATTTTCTTCGTCG
GCGTGGTCGCTTGTTGCGTGTTCGCCGGCGTGCCGATCGCTTTCGGATTTGGCCTCGCGATCTACGGCTATCTGGCGCTG
ACCACCTCGACGCCGGTGATGGTGCTGGTCGGCCGCATGGACGAGGGCATGAGCCATCTGATCCTGCTGTCGGTGCCGCT
GTTCGTCTTCCTCGGCCTGCTGATCGAGATGACCGGGATGGCGCGGGCGATGGTGGCGTTCCTCGCCAGCCTGCTCGGCC
ATGTCCGCGGCGGCCTGCATTATGTGCTGGTCGGCGCGATGTATCTGGTCTCCGGCATCTCCGGCTCCAAGGCCGCCGAC
ATGGCGGCGGTGGCGCCGGTGCTGTTTCCCGAGATGAAAGAGCGCGGCGCCAAGCCGGGCGATCTGGTCGCCCTGCTCGC
CGCCACCGGCGCCCAGACGGAAACCATTCCGCCGAGCCTGGTGCTGATCACCATCGGCTCGGTGACCGGCGTGTCGATCG
CGGCGCTGTTCACCGGCGGCCTGCTGCCGGGTGTCGTGCTGGCGATCACGCTGTCGATGCTGGTGTGGTGGCGCTATCGC
GACGAGGATCTCAGCCACATCAGGCGCGCCAGCGGCGCCCAGATCGGCAAGACGCTGATCATTGCCCTGCCCGCATTGGC
GCTGCCCTTCGTGATCCGCGCCGCCGTGGTCGAAGGCGTCGCCACCGCCACCGAAGTCTCGACCATCGGCATCGTCTATG
CGGTGTTCGCGGGGCTTCTGATCTACCGGAAGTTCGATTTTCGGCGGCTGAGGCCGATGCTGGTCGACACCGCGGCGCTG
TCCGGCGCGATCCTGCTGATCATCGGCACCGCCACCGGCATGGCCTGGGGGCTGACGCAATCCGGCTTCTCGCGATCGCT
GGCCACCGCCATGACCGGCCTGCCCGGCGGCCCCGCGACCTTTCTCGCGGTGTCGATCGTGGCCTTCGTAATCCTCGGCA
GCGTGCTCGAAGGTATTCCGGCGATCGTGCTGTTCGGGCCGCTGCTGTTCCCGATCGCCCGCGCCGTCGGCATCCACGAG
GTGCACTACGCCATGGTGGTCATTCTGGCGATGGGCATCGGATTGTTCGCACCGCCGTTCGGGGTCGGCTATTATGCGGC
CTGCGCGATCGGCCGGGTCGATCCGGCCGAGGGCGTGCGTCCGATCCTGGGTTATCTGCTGGCGCTGATGGTCGGCTTGA
TCATCGTCGCCGCGGTGCCGTGGATTTCGATCGGATTTCTGTGA

Upstream 100 bases:

>100_bases
GCGCGCCGCCGGCTTCTACGCCGAATGGAAAGGCAAATACGGCGAGCAGGCCTGGTCGCTGCTGGAGAAATCCGTCGGCA
AGCTCGCCTGATCCGTCGCG

Downstream 100 bases:

>100_bases
GGCGTTGCGGGTCTTCGGACGCGCCGCCATCGTGAACTGAGAGGCAGGTCGTCATGAGCGTTCCGCAAGGTCACTACAGC
ATCGGGCTGGACAAGACGCC

Product: TrapT dctQ-M fusion permease, dicarboxylate transport

Products: NA

Alternate protein names: N-acetylneuraminic acid permease; N-acetylneuraminic acid transporter; Neu5Ac permease [H]

Number of amino acids: Translated: 627; Mature: 626

Protein sequence:

>627_residues
MTHAEIPQLAAGKPLDIATRRSLIGALDSGLGLLVEIPAALLVVAEIVVLFAGVVSRYVFHSPLIWSDELASILFLWLAM
FGAAVAFRRGEHMRMTALVASASPRLRAFLDLVAICAALAFLLLIAAPAYDYAYEESYITTPALSLSNAWRAAALPVGIV
LMTLFALLRLIRFGDWRLVAGAALTVAVLIGAFWLAQPLFKPLGNLNLVIFFVGVVACCVFAGVPIAFGFGLAIYGYLAL
TTSTPVMVLVGRMDEGMSHLILLSVPLFVFLGLLIEMTGMARAMVAFLASLLGHVRGGLHYVLVGAMYLVSGISGSKAAD
MAAVAPVLFPEMKERGAKPGDLVALLAATGAQTETIPPSLVLITIGSVTGVSIAALFTGGLLPGVVLAITLSMLVWWRYR
DEDLSHIRRASGAQIGKTLIIALPALALPFVIRAAVVEGVATATEVSTIGIVYAVFAGLLIYRKFDFRRLRPMLVDTAAL
SGAILLIIGTATGMAWGLTQSGFSRSLATAMTGLPGGPATFLAVSIVAFVILGSVLEGIPAIVLFGPLLFPIARAVGIHE
VHYAMVVILAMGIGLFAPPFGVGYYAACAIGRVDPAEGVRPILGYLLALMVGLIIVAAVPWISIGFL

Sequences:

>Translated_627_residues
MTHAEIPQLAAGKPLDIATRRSLIGALDSGLGLLVEIPAALLVVAEIVVLFAGVVSRYVFHSPLIWSDELASILFLWLAM
FGAAVAFRRGEHMRMTALVASASPRLRAFLDLVAICAALAFLLLIAAPAYDYAYEESYITTPALSLSNAWRAAALPVGIV
LMTLFALLRLIRFGDWRLVAGAALTVAVLIGAFWLAQPLFKPLGNLNLVIFFVGVVACCVFAGVPIAFGFGLAIYGYLAL
TTSTPVMVLVGRMDEGMSHLILLSVPLFVFLGLLIEMTGMARAMVAFLASLLGHVRGGLHYVLVGAMYLVSGISGSKAAD
MAAVAPVLFPEMKERGAKPGDLVALLAATGAQTETIPPSLVLITIGSVTGVSIAALFTGGLLPGVVLAITLSMLVWWRYR
DEDLSHIRRASGAQIGKTLIIALPALALPFVIRAAVVEGVATATEVSTIGIVYAVFAGLLIYRKFDFRRLRPMLVDTAAL
SGAILLIIGTATGMAWGLTQSGFSRSLATAMTGLPGGPATFLAVSIVAFVILGSVLEGIPAIVLFGPLLFPIARAVGIHE
VHYAMVVILAMGIGLFAPPFGVGYYAACAIGRVDPAEGVRPILGYLLALMVGLIIVAAVPWISIGFL
>Mature_626_residues
THAEIPQLAAGKPLDIATRRSLIGALDSGLGLLVEIPAALLVVAEIVVLFAGVVSRYVFHSPLIWSDELASILFLWLAMF
GAAVAFRRGEHMRMTALVASASPRLRAFLDLVAICAALAFLLLIAAPAYDYAYEESYITTPALSLSNAWRAAALPVGIVL
MTLFALLRLIRFGDWRLVAGAALTVAVLIGAFWLAQPLFKPLGNLNLVIFFVGVVACCVFAGVPIAFGFGLAIYGYLALT
TSTPVMVLVGRMDEGMSHLILLSVPLFVFLGLLIEMTGMARAMVAFLASLLGHVRGGLHYVLVGAMYLVSGISGSKAADM
AAVAPVLFPEMKERGAKPGDLVALLAATGAQTETIPPSLVLITIGSVTGVSIAALFTGGLLPGVVLAITLSMLVWWRYRD
EDLSHIRRASGAQIGKTLIIALPALALPFVIRAAVVEGVATATEVSTIGIVYAVFAGLLIYRKFDFRRLRPMLVDTAALS
GAILLIIGTATGMAWGLTQSGFSRSLATAMTGLPGGPATFLAVSIVAFVILGSVLEGIPAIVLFGPLLFPIARAVGIHEV
HYAMVVILAMGIGLFAPPFGVGYYAACAIGRVDPAEGVRPILGYLLALMVGLIIVAAVPWISIGFL

Specific function: Part of the tripartite ATP-independent periplasmic (TRAP) transport system siaPT involved in the uptake of sialic acid [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the TRAP transporter large permease family [H]

Homologues:

Organism=Escherichia coli, GI48994950, Length=392, Percent_Identity=28.0612244897959, Blast_Score=142, Evalue=6e-35,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010656
- InterPro:   IPR007387
- InterPro:   IPR004681 [H]

Pfam domain/function: PF06808 DctM; PF04290 DctQ [H]

EC number: NA

Molecular weight: Translated: 65834; Mature: 65703

Theoretical pI: Translated: 8.79; Mature: 8.79

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTHAEIPQLAAGKPLDIATRRSLIGALDSGLGLLVEIPAALLVVAEIVVLFAGVVSRYVF
CCCCCCCHHCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
HSPLIWSDELASILFLWLAMFGAAVAFRRGEHMRMTALVASASPRLRAFLDLVAICAALA
HCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHH
FLLLIAAPAYDYAYEESYITTPALSLSNAWRAAALPVGIVLMTLFALLRLIRFGDWRLVA
HHHHHHCCHHHHHHCCCCCCCCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHH
GAALTVAVLIGAFWLAQPLFKPLGNLNLVIFFVGVVACCVFAGVPIAFGFGLAIYGYLAL
HHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHH
TTSTPVMVLVGRMDEGMSHLILLSVPLFVFLGLLIEMTGMARAMVAFLASLLGHVRGGLH
HCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHH
YVLVGAMYLVSGISGSKAADMAAVAPVLFPEMKERGAKPGDLVALLAATGAQTETIPPSL
HHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCCCCCCCE
VLITIGSVTGVSIAALFTGGLLPGVVLAITLSMLVWWRYRDEDLSHIRRASGAQIGKTLI
EEEEECCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCHHHHHHHH
IALPALALPFVIRAAVVEGVATATEVSTIGIVYAVFAGLLIYRKFDFRRLRPMLVDTAAL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SGAILLIIGTATGMAWGLTQSGFSRSLATAMTGLPGGPATFLAVSIVAFVILGSVLEGIP
CCEEEEEEECCCCHHHCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
AIVLFGPLLFPIARAVGIHEVHYAMVVILAMGIGLFAPPFGVGYYAACAIGRVDPAEGVR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCCCCCHH
PILGYLLALMVGLIIVAAVPWISIGFL
HHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
THAEIPQLAAGKPLDIATRRSLIGALDSGLGLLVEIPAALLVVAEIVVLFAGVVSRYVF
CCCCCCHHCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
HSPLIWSDELASILFLWLAMFGAAVAFRRGEHMRMTALVASASPRLRAFLDLVAICAALA
HCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHH
FLLLIAAPAYDYAYEESYITTPALSLSNAWRAAALPVGIVLMTLFALLRLIRFGDWRLVA
HHHHHHCCHHHHHHCCCCCCCCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHH
GAALTVAVLIGAFWLAQPLFKPLGNLNLVIFFVGVVACCVFAGVPIAFGFGLAIYGYLAL
HHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHH
TTSTPVMVLVGRMDEGMSHLILLSVPLFVFLGLLIEMTGMARAMVAFLASLLGHVRGGLH
HCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHH
YVLVGAMYLVSGISGSKAADMAAVAPVLFPEMKERGAKPGDLVALLAATGAQTETIPPSL
HHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCCCCCCCE
VLITIGSVTGVSIAALFTGGLLPGVVLAITLSMLVWWRYRDEDLSHIRRASGAQIGKTLI
EEEEECCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCHHHHHHHH
IALPALALPFVIRAAVVEGVATATEVSTIGIVYAVFAGLLIYRKFDFRRLRPMLVDTAAL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SGAILLIIGTATGMAWGLTQSGFSRSLATAMTGLPGGPATFLAVSIVAFVILGSVLEGIP
CCEEEEEEECCCCHHHCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
AIVLFGPLLFPIARAVGIHEVHYAMVVILAMGIGLFAPPFGVGYYAACAIGRVDPAEGVR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCCCCCHH
PILGYLLALMVGLIIVAAVPWISIGFL
HHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]