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The map label for this gene is siaP [H]

Identifier: 86749803

GI number: 86749803

Start: 3069926

End: 3070945

Strand: Reverse

Name: siaP [H]

Synonym: RPB_2686

Alternate gene names: 86749803

Gene position: 3070945-3069926 (Counterclockwise)

Preceding gene: 86749804

Following gene: 86749802

Centisome position: 57.6

GC content: 64.9

Gene sequence:

>1020_bases
ATGAGCGTTTCGCGCAGGACATTGTTGCAGGCATCGGCGGCGGCGGTCGCGCTCGGCGGCATCGGGGCGCCGTTCGTGGC
GCGCGCGGCGGAGGCCGAGTTCGTCTACAAATACGCCAACAACCTGCCCGACACCCATCCGATGAACATCCGCGCCCGCG
AGATGGCGGCGGCGATCAAGGCCGAGACCAATGGCCGGGTCCAGATCGACATTTTCCCGAGCAACCAGCTCGGCTCCGAC
ACCGACATGCTGAGCCAGATCCGCTCCGGCGGCGTCGAGTTCTTCACACTGTCCGGCCTGATCCTGTCGACGCTGGTGCC
GGCGGCCTCGATCAACGGTATCGGCTTCGCATTCCCGGACTACGACACGGTCTGGAAAGCGATGGACGGCGAGCTCGGCG
GCTATGTGCGCGGCGAGATCGGCAAGGCCGGGCTGGTGGTGATGGACAAGATCTGGGACAACGGCTTCCGCCAGACCACG
ACCTCGACCCGGCCGATCACCGGCCCGGACGACTTCAAGGGCCTCAAGATCCGCGTGCCGGTGTCGCCGCTGTGGACCTC
GATGTTCAAGGCGTTCGACGCCTCGCCCGCCTCGATCAATTTCAGCGAGGTCTATTCGGCGCTGCAGACCAAGGTCGTCG
AAGGCCAGGAGAACCCGCTGGCGATCATTTCGACCGCGAAGCTCTATGAAGTGCAGAAATACTGCTCGCTGACCAATCAT
ATGTGGGACGGCTTCTGGTTCCTCGCCAACCGCCGCGCCTGGGAACGGCTGCCAGCCGATCTGCGCGACATCGTCGCCAG
GAACATCAACGCCGCCGGCGTCAATCAGCGCGCCGACGTCGCCAAGCTCAACGCCGGCCTGAAGGACGAACTCGCCACCA
AGGGCCTGACCTTCAACCAGCCGACCATCGGGCCGTTCCGCGACAAGCTGCGCGCCGCCGGCTTCTACGCCGAATGGAAA
GGCAAATACGGCGAGCAGGCCTGGTCGCTGCTGGAGAAATCCGTCGGCAAGCTCGCCTGA

Upstream 100 bases:

>100_bases
CGGAATTCGCTTGACCGCGCTGGGCCGAAATGATGACCAGAAGTCGGTCGACTCGACGGGTCGGCTCGCACAAGAAGACG
GCTTGGCTGGAGGATTCGAA

Downstream 100 bases:

>100_bases
TCCGTCGCGATGACCCACGCCGAGATCCCGCAACTGGCGGCTGGAAAGCCGCTCGACATTGCGACGCGCAGGTCGCTGAT
CGGCGCGTTGGACTCCGGGC

Product: TRAP dicarboxylate transporter, DctP subunit

Products: NA

Alternate protein names: Extracytoplasmic solute receptor protein siaP; N-acetylneuraminic-binding protein; Neu5Ac-binding protein [H]

Number of amino acids: Translated: 339; Mature: 338

Protein sequence:

>339_residues
MSVSRRTLLQASAAAVALGGIGAPFVARAAEAEFVYKYANNLPDTHPMNIRAREMAAAIKAETNGRVQIDIFPSNQLGSD
TDMLSQIRSGGVEFFTLSGLILSTLVPAASINGIGFAFPDYDTVWKAMDGELGGYVRGEIGKAGLVVMDKIWDNGFRQTT
TSTRPITGPDDFKGLKIRVPVSPLWTSMFKAFDASPASINFSEVYSALQTKVVEGQENPLAIISTAKLYEVQKYCSLTNH
MWDGFWFLANRRAWERLPADLRDIVARNINAAGVNQRADVAKLNAGLKDELATKGLTFNQPTIGPFRDKLRAAGFYAEWK
GKYGEQAWSLLEKSVGKLA

Sequences:

>Translated_339_residues
MSVSRRTLLQASAAAVALGGIGAPFVARAAEAEFVYKYANNLPDTHPMNIRAREMAAAIKAETNGRVQIDIFPSNQLGSD
TDMLSQIRSGGVEFFTLSGLILSTLVPAASINGIGFAFPDYDTVWKAMDGELGGYVRGEIGKAGLVVMDKIWDNGFRQTT
TSTRPITGPDDFKGLKIRVPVSPLWTSMFKAFDASPASINFSEVYSALQTKVVEGQENPLAIISTAKLYEVQKYCSLTNH
MWDGFWFLANRRAWERLPADLRDIVARNINAAGVNQRADVAKLNAGLKDELATKGLTFNQPTIGPFRDKLRAAGFYAEWK
GKYGEQAWSLLEKSVGKLA
>Mature_338_residues
SVSRRTLLQASAAAVALGGIGAPFVARAAEAEFVYKYANNLPDTHPMNIRAREMAAAIKAETNGRVQIDIFPSNQLGSDT
DMLSQIRSGGVEFFTLSGLILSTLVPAASINGIGFAFPDYDTVWKAMDGELGGYVRGEIGKAGLVVMDKIWDNGFRQTTT
STRPITGPDDFKGLKIRVPVSPLWTSMFKAFDASPASINFSEVYSALQTKVVEGQENPLAIISTAKLYEVQKYCSLTNHM
WDGFWFLANRRAWERLPADLRDIVARNINAAGVNQRADVAKLNAGLKDELATKGLTFNQPTIGPFRDKLRAAGFYAEWKG
KYGEQAWSLLEKSVGKLA

Specific function: Part of the tripartite ATP-independent periplasmic (TRAP) transport system siaPT involved in the uptake of sialic acid. This protein specifically binds sialic acid [H]

COG id: COG1638

COG function: function code G; TRAP-type C4-dicarboxylate transport system, periplasmic component

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial solute-binding protein 7 family [H]

Homologues:

Organism=Escherichia coli, GI1790004, Length=288, Percent_Identity=28.4722222222222, Blast_Score=145, Evalue=4e-36,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018389
- InterPro:   IPR004682 [H]

Pfam domain/function: PF03480 SBP_bac_7 [H]

EC number: NA

Molecular weight: Translated: 37041; Mature: 36909

Theoretical pI: Translated: 9.40; Mature: 9.40

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVSRRTLLQASAAAVALGGIGAPFVARAAEAEFVYKYANNLPDTHPMNIRAREMAAAIK
CCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHH
AETNGRVQIDIFPSNQLGSDTDMLSQIRSGGVEFFTLSGLILSTLVPAASINGIGFAFPD
CCCCCEEEEEEECCCCCCCHHHHHHHHHHCCCEEEEHHHHHHHHHHHHHCCCCCEECCCC
YDTVWKAMDGELGGYVRGEIGKAGLVVMDKIWDNGFRQTTTSTRPITGPDDFKGLKIRVP
HHHHHHHHCCCCCCEEECCCCCCCEEEEHHHHCCCCCCCCCCCCCCCCCCCCCCEEEEEC
VSPLWTSMFKAFDASPASINFSEVYSALQTKVVEGQENPLAIISTAKLYEVQKYCSLTNH
CCHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCCCCEEEEEHHHHHHHHHHHHHHHH
MWDGFWFLANRRAWERLPADLRDIVARNINAAGVNQRADVAKLNAGLKDELATKGLTFNQ
HCCCEEEECCCHHHHHCCHHHHHHHHHCCCCCCCCCCHHHHHHCCCCHHHHHHCCCCCCC
PTIGPFRDKLRAAGFYAEWKGKYGEQAWSLLEKSVGKLA
CCCCHHHHHHHHCCCHHHHCCCCHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SVSRRTLLQASAAAVALGGIGAPFVARAAEAEFVYKYANNLPDTHPMNIRAREMAAAIK
CCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHH
AETNGRVQIDIFPSNQLGSDTDMLSQIRSGGVEFFTLSGLILSTLVPAASINGIGFAFPD
CCCCCEEEEEEECCCCCCCHHHHHHHHHHCCCEEEEHHHHHHHHHHHHHCCCCCEECCCC
YDTVWKAMDGELGGYVRGEIGKAGLVVMDKIWDNGFRQTTTSTRPITGPDDFKGLKIRVP
HHHHHHHHCCCCCCEEECCCCCCCEEEEHHHHCCCCCCCCCCCCCCCCCCCCCCEEEEEC
VSPLWTSMFKAFDASPASINFSEVYSALQTKVVEGQENPLAIISTAKLYEVQKYCSLTNH
CCHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCCCCEEEEEHHHHHHHHHHHHHHHH
MWDGFWFLANRRAWERLPADLRDIVARNINAAGVNQRADVAKLNAGLKDELATKGLTFNQ
HCCCEEEECCCHHHHHCCHHHHHHHHHCCCCCCCCCCHHHHHHCCCCHHHHHHCCCCCCC
PTIGPFRDKLRAAGFYAEWKGKYGEQAWSLLEKSVGKLA
CCCCHHHHHHHHCCCHHHHCCCCHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA